개에서 결직장 연접부의 림프종 1례

이재일,이수진,김영석,김명진,조성환,신상태,이영원,김명철 충남대학교 수의과대학 동물의과학연구소 2003 動物醫科學硏究誌 Vol.11 No.-

A five years old female Shih-tzu was referred to the veterinary medical teaching hospital at Chungnam national university with soft bloody diarrhea and tenesmus. On rectal palpation, solid mass was palpated in colorectal region. In radiographs, small intestine was deviated cranially, descending colon and rectal junction were deviated caudoventrally in lateral projection of the abdomen. In ultrasonographs, hypoechoic nodulation of mesenteric lymph node in colorectal junction, mixed echoic thickening of colorectal wall and irregular margination were observed. Rectal endoscopy revealed that colorectal men was partially obstructed due to compression of the mass. Also, severe ulceration, inflammation and hemorrhage were also observed in descending colon. The mass was resected through the laparotomy. In histopathology, it was diagnosis of lymphoma in the colorectal junction.

서울의 Penicillinase Producing Neisseria Gonorrhoeae 발생빈도(1996)

김재홍,황동규,전재홍,김윤석,김중환,김용준,이창균,임동진,김현수,조창근,김경문,박상훈,전우형,김희성,이호정,차명수,김갑형,김형석,김석우,황지환,박병순,권오상,이민수,송기훈,성소영,이인섭,부태성 대한화학요법학회 1999 대한화학요법학회지 Vol.17 No.2

Background : In recent years, gonorrhea has been panedemic and remains one of the most commom STDs in the world, especially in developing countries. Objective & Methods: For the detection of a more effective therapeutic regimen and assessing the prevalence of PPNG, we have been trying to study the patients who have visited the VD Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results: In 1996, 139 strains of N. gonorrhoeae were isolated, among which 53(39.0%) were PPNG. Conclusion: Our results suggests that after a peak of 74.3% in 1993, the prevalence of PPNG in Seoul is gradually declining.

GC에 의한 사과주 발효중 알코올류 및 유기산류의 분석

이선현,이명환 서울여자대학교 자연과학연구소 1995 자연과학연구논문집 Vol.6 No.-

S. Cerevisiae와 K Lactis 균주를 설탕 농도가 7%, 13.5% 20%인 사과쥬스에 각각 접종하고 담금한 6종의 사과주 발효 과정중 alcohols 성분과 organic acids 성분등을 검토한 결과는 다음과 같다. 1. pH는 담금직후 1일에 4.02~4.33 이었으며 점차적으로 감소하여 발효 7일에 3.13~3.46의 낮은 값을 나타내고 9일 부터는 감소하는 정도가 작아지면서 12일에는 3.02~2.78의 최저값을 나타내었다. 각 시험구 간에는 SCⅡ가 가장 낮았고 SCⅢ, KLⅢ, KLⅠ, KLⅡ 그리고 SCⅠ의 순이었다. 2. 총산은 발효과정중의 증가를 보이며 담금 1일에 0.09~0.11%로 부터 담금 12일에 최대값인 0.72~2.44%의 값을 나타내었으며 각 시험구의 총산 변화는 pH 변화와 같은 경향을 보여주고 있다. 3. 각종 alcohol을 측정한 결과 각 시험구에서 3.12-11.63ml/l로 ethyl alcohol 함량이 다른 alcohol보다 현저하게 많았다. 각 시험구 간의 ethyl alcohol 생성량으로 보아 SCⅢ와 KLⅢ에서의 함량이 가장 높은 것을, SCⅡ와 KLⅠ은 가장 낮은 값을 나타내었다. 그 외에 methyl, n-propyl, i-amyl alcohol은 각각 2.84-26.46, 2.58-8.93, 9.18-50.98ppm으로 소량 함유되어 있었다. 4. 각종 organic acid를 측정한 결과 lactic acid, succinic acid, maleic acid, malonic acid, artaric acid의 함량(ppb)이 0.35-5.05, 6.50-22.09, 0.39-2.75, 0.46-0.96으로 전체적으로 증가하는 경향을 보였고 이 중에서는 lactic acid 와 succinic acid가 다소 높은 값을 나타내었다. 5. 무기금속 성분 함량(ppm)은 Ca가 SCⅢ와 KLⅢ에서 84.82, 95.36으로 가장 높은 값을, SCⅠ과 KLⅠ에서 67.29, 52.74로 가장 낮은 값을 보였으며 K는 SCⅡ와 KLⅠ이 156.87, 169.58로 가장 높은 값을 보이고 SCⅢ와 KLⅢ가 가장 낮은 154.56, 139.49의 값을 나타냈다. Apple wine was prepared by using apple juice which was inoculated with Saccharomyces cerevisiae and Kluyveromyces Lactis. Those chimical compositions such as alcohols and organic acids were determined with gas chromatographyt to investigate the variation of its content by the fermentation. Alcohols such as methyl, n-propyl, I-amyl alcohols were found in the most apple wine. Alcohol contents in teh groups SCⅢ and KLⅢ were slightly higher than SCⅡ KLⅠ group. Lactic acid and succinic acid were concentrated and organic acids such as malonic, succinic, maleic, tartaric acids were also detected in the most samples. The acid contents were increased whereas the pH were decreased as the duration of fermentation was prolonged. The value of pH was lowest in the SCⅡ group and was reduced in the order of SCⅠ, KLⅢ, KLⅠ, KLⅡ and SCⅠ group. The total acid content was highest in SCⅡ. The total acidities and pH values were showed almost the similar changing pattern. The metal contents were increased as the fermentation time was prolonged. The contents of Ca and K which were transferred from the raw material were found to be 52.74-95.36, and 139.49-169.58 ppm, respectively.

젖소 足皮膚炎에 대한 오존연고의 治療 效果

이수진,전무형,조성환,김덕환,박창식,김명철 충남대학교 형질전환복제돼지연구센터 2007 논문집 Vol. No.10

Thirty dairy cows with pododermatitis were selected and treatment effect of ozone ointment for bovine pododermatitis was investigated. In addition, bactericidal effect of ozone ointment on etiological agent of bovine pododermatitis was evaluated. The pathohistological examination for the pododermatitis, according to application with ozone ointment was investigated. Thirty dairy cows were divided two groups: control group(vaseline group: 15 cows), treatment group(ozone ointment group: 15 cows). Various parameters were evaluated in terms of the lameness score, swelling score, lesion score, WBC, neutrophil, pathohistological finding, and antimicrobial action. As compared with vaseline group, ozone ointment group revealed significant decrease of lameness (p<O.05), swelling (p<O.O1) and lesion score (p<O.05) were shown in hoof lesions on 14 days after application. In hematological findings, WBC count revealed slightly high values within normal range before treatment, however, this was I Corresponding author improved on 14 days after application of ozone ointment. The number of neutrophils was slightly higher than that of normal, however. this was improved on 14 days after application of ozone ointment. In pathohistological findings, normal dermal tissue was found in tissues with pododermatitis on 14 days after application of ozone ointment. In antimicobial action, marked decrease rate of bacteria was observed in feet of all cases treated with ozone ointment. The decreasing rate of bacteria in anaerobic culture was higher than that in aerobic culture.

젖소 足皮膚炎에 대한 오존수의 治療 效果

이수진,조성환,전무형,김덕환,박창식,한홍율,김명철 충남대학교 형질전환복제돼지연구센터 2007 논문집 Vol. No.10

This study was carried out to determine therapeutic the effect of ozonated water therapy on bovine pododermatitis. In addition, bactericidal effect of ozonated water on etiological agent of bovine pododermatitis was examined. The pathohistological examination for the pododermatitis, according to application with ozonated water and ozone ointment was investigated. Thirty healthy cattle were divided two groups(each of 15) : control group (povidone group), treatment group (ozone solution group). Various parameters were evaluated in terms of the lameness score, swelling score, lesion score, WBC count, neutrophil count, pathohistological finding, and antimicrobial action. The decrease of lameness and lesion score were shown in hoof lesions on 14 days after application of ozonated water. Significant decrease of swelling was shown in hoof lesions on 14 days 1 Corresponding author after application of ozonated water(p < 0.01). In hematological findings, WBC count revealed values within normal range. The number of neutrophils was slightly higher than that of normal, however, this was improved on 14 days after application of ozonated water. In pathohistological findings, recovery was rapid macroscopically and microscopically in the treatment with ozonated water on the hoof lesions and ozonated water was effective. In antimicobial action, bactericidal effect was observed in treatment with ozonated water on the hoof lesions and ozonated water was effective.

초등학교 과학교과 생활통지표의 실태

이수환, 송명섭 대구교육대학교 과학교육연구소 2003 과학·수학교육연구 Vol.26 No.-

GC와 GC-MS에 의한 어란의 지방산 분석

이주현,전명숙,이명환 서울여자대학교 자연과학연구소 1995 자연과학연구논문집 Vol.6 No.-

9종류의 어란에서 지방산을 추출하여 GC-MS로 분석한 결과 다음과 같은 결과를 얻었다. 1. 어란중 지방산을 GC와 GC-MS로 분석할 때 초기온도를 60°C로 하고 승온률을 9°C/min, 마지막 온도를 220°C로 하는 승온법이 목적 성분을 분리하는데 가장 좋은 결과를 얻었다. 2. 가자미, 날치, 대구, 명란, 농어, 성어, 오징어, 참치, 청어의 알에서 지방산을 추출하여 GC로 분석한 결과 포화 지방산은 myristic acid, palmitic acid, stearic acid, arachidic acid가 검출 되었고, 불포화 지방산은 oleic acid, linolenic acid 가 각각 확인 되었다. 3. 포화 지방산은 myristic acid가 명태알에 11.8㎍/g 으로 가장 많이 함유되어 있었고, palmitic acid는 오징어알에서 106.32㎍/g으로 가장 많이 함유되어 있었다. Stearic acid는 농어알에 53.03㎍/g, arachidic acid는 대구알에 8.5㎍/g으로 가장 많은 양이 함유되어 있었다. 4. 불포화 지방산인 oleic acid와 linolenic acid의 함량을 분석한 결과 oleic acid는 가자미 알에 linolenic acid는 명태알에 각각 109.12㎍/g, 62.48㎍/g으로 가장 많은 양이 함유되어 있었다. Fatty acids were extracted from the roe of flounder, flying fish, Pacific cod, Alaska Pollack, mero, shark, squid, tuna, and herring. They were methylated and analyzed by GC and GC-MS. Most of fatty acids found from 9 different roe were myristic acid, palmitic acid, stearic acid, arachidic acid, oleic acid, and linolenic acid. The roe of Alaska Pollack, squid, mero, and Pacific cod contained 11.8ug/g, 62.48 ug/g, of unsaturated fatty acids such as oleic acid and linolenic acid, respectively. The roe of flounder and shark had higher content unsaturated fatty acids than rest of the roe. The roe of Pacific cod, Alaska Pollack, mero, squid, tuna, and herring had larger amount of saturated fatty acids than the rest of the roe.

뇌실주위 백질연화증 발생 위험인자

이동환,서은숙,이우령,조명환,박재옥 순천향의학연구소 1998 Journal of Soonchunhyang Medical Science Vol.4 No.1

The twenty newborn infants with periventricular leukomalacia(PVL) who were admitted to the neonatal intensive care unit of SoonChunHyang University Hospital from May 1, 1993 to July 30, 1997, were investigated for risk factors. Control group were the age matched 20 neonates who were admitted at the same time of study period. The results were as follows: 1) Mean gestational age was 31 week and mean birth weight 1665gm. 2) PVL's were located in the parietal region in 10 cases, fronto-occipital in 7 cases and parieto-occipital region in 3 cases. 3) Multiple logistic regression analysis for the risk factors of PVL showed that low birth weight, intraventricular hemorrhage, bronchopulmonary dysplasia, necrotizong enterocolitis and ventilator apply were the most significant contributing factor(P<0.05). 4) In a follow-up ultrasonograptic findings, 11 among 14 neonates with localized PVL were normalized whereas, all of 6 extensive PVL had the sequale of ventriculomegaly or cerebral atrophy. 5) In a follow-up neurologic examination, the poorer sequale including spastic diplegia or quadriplegia was associated with the larger, the more extensive PVL.

Epichlorohydrin Polymer의 배합에 의한 성능변화 및 그 응용에 관한 연구

李明煥 서울여자대학교 1978 서울여자대학논문집 Vol.- No.7

The purpose of this study is to establish an effective way to utilize the application of Epichlorohydrin polymer compound. The results are shown as follow: 1. For the most effective heat-resisting compound of epichlorohydrin hose and tube either red lead or Dyphos/Dythal family is recommended to be used as acid acceptor, either NBC and Niclate as fire-fighting aid, and ethylene thiourea (NA-22, Thiate N or Pennac CRA) for crosslinking. Imidazol too appears to be the most effective for air aging, and especially the vulcanizer made under sufficient curing time turns out to have excellent heat-resisting effect. For the coulping agent Silane-189 was used, and when silica was charged in, long-range heat-proof quality was far better than that when in black compounding . 2. In long-range heat-proof air aging effect heat-resisting epichloro hydrin polymer compund was superior to CR, CSM or NBR, but in air aging effect was a little inferior heat-proof EPDM. In the meantime, epichlorohydrin only polymer compound shows a higher numerical value in long-range aging test than EPDM. The compound which showed the highest antioxidizing effect was ACM/ECO blend.

마늘의 Thiosulfinate 소장에 관한 연구

이명환,김주선 서울여자대학교 자연과학연구소 1990 자연과학연구논문집 Vol.1 No.-

마늘외 처리온도 및 시간에 따른 thiosulfinate 함량의 변화와 실온 및 고온추출시 황화합물의 성분 변화를 조사하기 위하여 N-ethylmaleimide 발색반응과 UV Spectrophotometer 및 gas chromatograph를 이용하여 분석한 결과 다음과 같은 결과를 얻었다. 처리온도 및 시간에 따른 thiosulfinate함량의 변화에 있어서 25℃, 50℃에서 5시간, 75℃에서 30분까지 존재하였으나, U.V spectrophotometer에 의한 검출에서는 75℃, 1시간과 100℃, 15분까지도 완전히 분해되지 않으며, 또한 diallyl disulfide의 양도 75℃, 15분보다 1시간에서 3배 정도 많았는데 이는 thiosulfinate가 분해되어 생성된 것으로 앞의 결과를 뒷받침해 주고 있다. 실온에서의 n-hexane 및 수증기 증류하여 얻은 추출물의 함량은 각각 0.10%, 0.12% 였으며 실온의 n-hexane추출물에서는 diallyl disulfide보다는 동정하지 못한 물질이 주물질이었으며 수증기 증류하여 얻은 정유에서는 diallyl disulfide가 주물질로 관찰되었다. The effects of heating time and temperature on the change of thiosulfinate content and the effects of n-hexane extraction and steam distillation on the change of sulfur compounds of garlic bulbs were investigated using N-ethylmaleimide color reaction, UV spectrophotometer and gas chromatograph. Thiosulfinate was detected in n-hexane extracts from garlic bulbs heated for 5 hours at 25℃ and 50℃ and for 30 minutes at 75℃ by the color reaction method. The UV spectrophotometer was more sensitive than the color reaction method to detect the thiosulfinate from even the extracts of samples heated for 1 hour at 75℃ and 15 minutes at l00℃.The quantity of diallyl disulfide which was formed from the decomposition of thiosulfinate increased to reach threefold values by 1 hour heating at 100℃ as compared with the samples heated for 15 minutes at 75℃, which well supported the above results. The steam distillation yielded extract of 0.12% which was mainly diallyl disulfide and the n-hexane extraction yielded extract of 0.10% at room temperature, however, the main compund was not diallyl disulfide but other unidentified compound.