Production and characterization of soluble human TNFRI-Fc and human HO-1(HMOX1) transgenic pigs by using the F2A peptide

Park, Sol Ji,Cho, Bumrae,Koo, Ok Jae,Kim, Hwajung,Kang, Jung Taek,Hurh, Sunghoon,Kim, Su Jin,Yeom, Hye Jung,Moon, Joonho,Lee, Eun Mi,Choi, Ji Yei,Hong, Ju Ho,Jang, Goo,Hwang, Joing-Ik,Yang, Jaeseok,Le Springer-Verlag 2014 Transgenic research Vol.23 No.3

서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)

김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1

In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.

변비 및 변실금 환자를 위한 휴대가 가능한 가정용 바이오피드백 치료기

지준근,차귀수,이문호 순천향대학교 부설 산업기술연구소 2001 순천향 산업기술연구소논문집 Vol.7 No.1

In this paper, biofeedback anal spincter control system is designed and implemented. This system is useful for training and cure anal spincter for idiopathic chronic constipation patient or idiopathic chronic and nerogenic fecal incontinence patient. This paper includes anal spincter EMG amplifier and signal processor in order to amplify and detect anal spincter EMG signal of several microvolts without distortion. It is also includes monitoring system to confirm anal spincter EMG signal using LED display and speaker sound output.

한국 정상인에서 연령에 따른 뇌혈류분포와 혈류예비능의 변화 : Tc-99m HMPAO SPECT 에 의한 연구

문대혁,이희경,송호천,이재태,범희승,손혜경,정환정,민정준,김지열 대한핵의학회 1999 핵의학 분자영상 Vol.33 No.3

Purpose: The aim of this study was to evaluate the normal values of regional cerebral blood flow (rCBF) and cerebrovascular reserve (CVR) in normal children to aged volunteers using Tc-99m HMPAO. Materials and Methods: Thirty four right-handed normal volunteers (20 males, 14 females, mean age 40.3±24.9 years, range 4 to 82 years) were underwent rest/acetazolamide (ACZ) brain SPECT using Tc-99m HMPAO and the sequential injection and subtraction method. rCBF was estimated on the basis of a semiquantitative approach by means of right/left ratio, region/cerebellum and region to whole brain ratios in frontal, parietal, temporal, and occipital lobes, basal ganglia, thalami, and cerebellum. CVR was measured by means of % perfusion increase calculated as % mean count change compared to rest rCBF in each regions. Results: Mean values of right to left ratios range from 1.004 to 1.018. rCBF was highest in cerebellum and lowest in basal ganglia and thalami. Frontal and temporal rCBF decreased while occipital and thalami rCBF increased according to age. No sexual difference of rCBF was noted. Mean CVR was 29.9±12.9%. Mean CVR significantly increased to late teens, and declined thereafter. After 6th decade, CVR in both frontal lobes, left parietal lobe and right basal ganglia decreased significantly with advancing age. There was no sexual difference of CVR. Conclusion: Quantitative assessment of CVR was possible by ACZ Tc-99m HMPAO brain SPECT. It revealed that rCBF and CVR changed according to age in normal Korean volunteers. There was no sexual difference.

저전력 움직임 추정을 위한 VLSI 설계

문지경,소현호,김진상,조원경 경희-다반 ASIC 설계교육센터 2003 경희-다반 ASIC센터 논문집 Vol.4 No.-

Many full searchblock matching (FSBM) architectures have been proposed for the motion estimation. However, the FSBM architectures need many computations and a lot of external memory accesses which are the main source of the power consumption. We propose an efficient low-power architecture for the full search block matching (FSBM) motion estimation by eliminating unnecessary computations and data reuse. Implementation results show the proposed motion estimator can save maximally about 9.3% power dissipation than a previous motion estimator.

역도 인상동작의 운동학적 분석

문영진,송주호,김지섭 한국운동역학회 2004 한국운동역학회지 Vol.14 No.2

Y. J. Moon, J. H. Song, J. S. Kim. A Kinematic Analysis of Snatch Technique in Weight-Lifting. Korean Journal of Sport Biomechanics, Vol. 14, No. 2, pp. 41-55, 2004. This study analyzed snatch technique in weight-lifting performed by female gold, silver, and copper medalists at the 75kg level in the 2002 Pusan Asian Games and obtained the following conclusions. 1. KSH used more extensor in the waist than those in ankles, knees, or hip joints during the second pull, So further training is required to manifest both each of joints and waist extensor effectively and thus for the line from shoulders through barbell to hip joints to form a smooth vertical pattern. 2. Contrary to those in other countries, Korean athlete KSH tended to be swift in starting but slow in the second pull section, showing less effectiveness in movement during the second pull; therefore, they must try to exert a swift movement in lockout. 3. KSH showed slowdown in the speed, which was a factor interfering with performance during second pull, despite the great maximum speed of moving barbell. It is important to use barbell sufficiently not to reduce the speed of vertical movement but rather to keep the speed increasing. 4. KSH, who kept doing inefficient movements such as failure to perform swift lockout after lifting the heel at the maximum angle of lower limbs, needs to reduce this meaningless extension of ankles, knees, or hip joints to exert energy effectively.

상아질 접착제의 중합 시간 조절에 따른 복합레진의 중합 수축 방향의 변화

배지현,오명환,김창근,손호현,엄정문,조병훈,권혁춘 대한치과보존학회 2001 Restorative Dentistry & Endodontics Vol.26 No.4

The purpose of this study was to evaluate the effect of adhesive curing timing on the direction of polymerization shrinkage of light-curing composite resin. In this study, the curing times of adhesive and composite resin were measured by differential scanning calorimeter(DSC). 28 extracted human molars were embedded in clear resin and box-type cavities were prepared. Based on DSC data. the experimental teeth were divided into 4 groups. Group 1: no bond: Group 2: late curing: Group 3: Intermediate curing: Group 4: Early curing. After treating with adhesive, the buccal cavities were filled with Z-100 hybrid composite resin and the lingual ones were filled with AEliteflo flowable composite resin. The depressions at the surface were measured by surface profilometer, then the specimens were embedded in clear resin and sectioned. Impressions were obtained and used to get epoxy resin replicas. The epoxy replicas were gold-coated and observed under SEM. Average Maximum Gap(AMG), Gap Proportion(GP), Average Marginal Index(AMI) were used to compare the shrinkage gap of each group. The results were statistically analyzed using the Kruskal-Wallis One Way ANOVA, Student-Newman-Keuls method. The results of this study were as follows. 1. Average Maximum Gap. Gap Proportion, Average Marginal Index and depression at the surface of Z-100 hybride composite resin were smailer than those of AEliteflo flowable composite resin(P(0.05) 2. When the bonding between composite resin and tooth structure was strong, the shrinkage gap was small, and depression at the surface was deep(P<0.05). 3. In the well-bonded group. light-curing composite resin shrank toward bonded cavity wall. not toward light source. The result suggested that the direction of polumerization shrinkage was affected by the quality of bonding in the dentin-resin interface. The strong was the bonding between composite resin and tooth structure, the smaller was the gap and the deeper was the depression at the surface. Then the flow to compensate the polymerization shrinkage proceeded from surface to bonded cavity wall.

원격 와이핑 작업을 위한 제어 기법

전지명,이승호,문일동,오재윤 전북대학교 공학연구원 ( 구 전북대학교 공업기술연구소 ) 2002 工學硏究 Vol.33 No.-

This study proposes a technique utilizing virtual information instead of real information in a teleoperated wiping operation. A teleoperation system composed of a master manipulator, a slave manipulator, and a real-time control system is used for this study. Both the master and slave manipulator have a kinematic structure effectively conveying and following the operator’s command respectively. The master manipulator uses DC servo motors to do a major role for counter balancing. A force sensor attached at the end of the slave manipulator’s end effector is used to measure a contact force. MATLAB/xPC Target is used for real-time control of the teleoperation system in Windows OS. This study proposes algorithms for generating the virtual force and the virtual velocity. They are generated as the master manipulator’s grip moves up and down, and back and forth. A force-force control technique proposing in this paper uses the virtual force as a reference input for the contact force control, and uses the virtual velocity as a reference input for control the slave manipulator’s horizontal movement. A PID controller is used as a local controller for the contact force control. In order to show the effectiveness of the proposing force-force control technique, experiments are performed on a plastic plate with two bumps.

건설장비와 농기계에서 배출되는 연도별 대기오염 배출량 변화추세

신문기,김호정,장영기,홍지형 한국대기환경학회 2003 한국대기환경학회지 Vol.19 No.6

The annual air pollution emissions from construction and agricultural equipments were estimated from 1987 through 2000. The annual numbers and operation hours of 5 major construction equipments (Excavator, Bulldozer, Loader, Fork lift, Crane) and 3 major agricultural equipments (Power Tiller, Agricultural Tractor, Combine) were investigated for emission estimation. And monthly variation factors of operation hours of construction equipment were investigated too. The NOx emission from construction equipment have been gradually increased since 1987 to 1997, but sharply decreased as -45% in 1998 due to economic crisis in Korea. The NOx emission was estimated as 64,300 ton/year from construction equipment, and as 23,300 ton/year from agricultural equipment in 2000.

조선업 근로자의 족부백선 유병률 및 관련 요인

서호석,유철인,이충렬,이지호,김양호,이원신,최지호,성경제,고재경,문기찬 大韓産業醫學會 2002 대한직업환경의학회지 Vol.14 No.4

목적: 울산지역에 소재한 대규모 조선업종 근로자 1,419명을 대상으로 족부백선의 유병률을 조사하고 족부백선의 유병률에 미치는 요인을 조사하여 족부백선의 작업관련성을 알고자 본 연구를 실시하였다. 방법: 근로자 건강진단시 족부백선의 유뮤를 확인하고, 현재 족부백선의 위험인자로 알려져 있는 여러 요인들과 작업, 환경적인 요인들에 대하여 설문조사를 실시하고, 족부백선의 임상적인 양상을 관찰하였다. 결과: 조사결과 족부백선의 유병률은 54.8%로 높게 나타났으며, 직종과 공동목욕탕 이용 유무, 안전화 착용유무, 작업형태, 가족력 유무가 족부백선이 유병률에 영향을 미치는 위험인자로 나타났으나, 다변량 분석결과 가족력과 공동목욕탕 이용만이 통계적으로 유의한 위험인자로 나타났으며(P<0.05), 안전화 착용은 통계적으로 유의하지 않았다. 결론: 이상의 결과에서 사업장내 근로자들의 족부백선의 높은 유병률과 관련된 직접적인 요인은 사업장내의 공동 목욕탕의 이용 여부와 족부백선의 가족력임을 확인할 수 있었으며, 많은 근로자들이 원인으로 지목한 안전화의 착용은 통계적인 유의성은 없었다. 따라서 족부백선이 작업과 직접적으로 관련되었다는 근거는 적은 것으로 보인다. 하지만 일반인보다 높은 유병률을 보이는 것으로 확인된 사업장내 족부백선의 유병률을 감소시키기 위해서는 위험인자로 최종 확인된 작업장 내의 공동 목욕탕의 철저한 위생관리와 함께 가족간의 감염을 예방히기 위한 개인위생관리가 필요하면, 비록 통계적인 유의성은 없었으나 여러 근로자들이 원인으로 지목한 안전화의 개선에도 노력해야 할 것으로 생각한다. Objectives: Recently, tinea pedis has been reprted to be a type of occupational dermatoses because of its high prevalence in specific working conditions. Although there is no doubt that the environment surrounding work places, the usual habits of workers erc ate intimately related to this skin conditions, there is some controversu as to whether or not this condition is a real occupational illness and what is the exact cause of the high prevalence of this illness is. In this study, the prevalence of tinea pedis in workers from the shipbuilding industry was investigated andthe risk factors of this disease were evaluated. This study also aimed to verify whether or not tinea pedis is one of the occupational diseases. Methods: The result of interviews, questionnaires and clinical findings from 1,419 workers who visited the occupational health center for an annual routine check for their health state were analyzed. Results: Among the 1,419 workers, 778 workers (54.8%)had tinea pedis. By simple logistic regression analysis, the prevalence of tinea pedis was found to e affected by some variables, including the jov category, the types of work, the kinds of footwear, whether or not they were using communal baths in the work places, and a family history of tinea pedis. In contrast, by multiple logistic regression analysis, only utilization of the communal baths in the work places and a family history of tinea pedis turned out to be statistically significant risk facrors. Conclusions: In this study, the major factors contributing to the high prevalence of tinea pedis are the use of communal baths in the workplace and a positive family history. However, the wearing of safety shoes was not statistically significant. Therefore, tinea pedis could not be confirmed to be an occupational disease. On the basis of these results, a solution to the environmental hygiene of communal bats and the personal hugiene of individuals needs to be improved in order to prevent tinea pedis.