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Kun Luo,Pengsheng Wang,Xiaoyan Lei,Yan Zhao 대한토목학회 2023 KSCE Journal of Civil Engineering Vol.27 No.10
Model similarity experiment is an effective method to predict the vibration response of track-box girder structure under complex working conditions. In this paper, the coupling similarity relationship between the layers of the multilayer structure is deduced theoretically. In addition, according to the elasticity similarity law and the π theorem, a track-box girder coupling vibration model with a 10:1 geometric similarity ratio was designed. The influence of parameters on the system similarity was further discussed, including the density and elastic modulus of track plate, the stiffness of fastener and CA mortar layer. Finally, a scale track-box girder model was built. Based on the modal test and finite element method, the model design and the similarity relation between prototype and model were verified. The results show that the scale model can be employed to forecast vibrations for an elevated track bridge, and the vibration level under different working conditions can be inverted from the model test results in model design. When the geometry size of a certain structural layer in the direction of load is much larger than that of the other structural layers, the similarity relation derived from the material properties of the structural layer is approximately equal to the similarity of the system between the prototype and the scale model.
The game strategy of the enterprise reliability development
Kun Tian,Chang"an Zhu,Xia Ge,Zhicheng Yao,Lei Li 인하대학교 정석물류통상연구원 2009 인하대학교 정석물류통상연구원 학술대회 Vol.2009 No.10
Due to the increasing importance of equipment reliability and asymmetric information between the military and military enterprises, it is of great practical significance to study equipment reliability. This paper first reviews the current prevalent game model of both entities, and points out its insufficiency. Then, to resolve the problem, the paper constructs a game model based on penalty mechanism and obtains an optimum equilibrium. Finally, this paper makes a detailed analysis on the game strategies of both participants, which provides useful suggestions to the equipment reliability improvement.
State Feedback Control Promotes Transition Efficiency of Bag Filters
Kun Li,Yukai Li,Rui Cong,Zheng Xu,Lei Zhang,Libing Liu,Song Zhang 제어·로봇·시스템학회 2024 International Journal of Control, Automation, and Vol.22 No.1
How to improve the efficiency of bag filters has attracted a considerable amount of attention. However, effective control of the transition stage, which plays an important role in reducing the time to reach a new steady state, still lacks research. Here, we utilize a nominal linear system with a time delay to characterize the transition stage. We introduce two state feedback mechanisms, namely linear matrix inequality based state-feedback robust controller and parameter-tuning controller based on nonlinear matrix inequality, into control process. Results of both genetic algorithms simulations and closed-loop control experiments show that these controllers dramatically shorten the transition stage compared to open-loop control. Furthermore, we find that parameter-tuning controller outperforms linear matrix inequality based state-feedback robust controller in terms of both stable time and steady error. These results are robust to different experimental settings. From industrial economic perspective, this technology could help to conserve energy and protect environment.
Do-Kun Yoon,Joo-Young Jung,Han-Back Shin,Moo-Sub Kim,최보영,Sunmi Kim,서태석,Keum Sil Lee,Lei Xing 한국물리학회 2016 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.69 No.5
The purpose of this study was to show a 3D printed reconstruction model of a bone destroyed by a comminuted fracture. After a thoracic limb of a cow with a comminuted fracture was scanned by using computed tomography, a scaffold was designed by using a 3D modeling tool for its reconstruction and fabricated by using a homemade medical 3D printer. The homemade medical 3D printer was designed for medical use. In order to reconstruct the geometry of the destroyed bone, we use the geometry of a similar section (reference geometry) of normal bone in the 3D modeling process. The missing part between the destroyed ridge and the reference geometry was filled with an effective space by using a manual interpolation. Inexpensive materials and free software were used to construct the medical 3D printer system. The fabrication of the scaffold progressed according to the design of reconstructed bone by using this medical 3D printer. The material of the scaffold was biodegradable material, and could be transplanted into the human body. The fabricated scaffold was correctly inserted into the fractured bone in place of the destroyed portion, with good agreement. According to physical stress test results, the performance of printing resolution was 0.1 mm. The average geometrical error of the scaffold was below 0.3 mm. The reconstructed bone by using the fabricated scaffold was able to support the weight of the human body. No process used to obtain the result was complex or required many resources. The methods and results in this study show several possible clinical applications in fields such as orthopedics or oncology without a need to purchase high-price instruments for 3D printing.
Qi‑Lei Dai,Kun Li,Kai‑Ren Meng,Zhou Fang,Wen Chen,Tian‑Bao Yang,Chi Feng,Jin‑Ming Wu,R. D. K. Misra 대한금속·재료학회 2023 METALS AND MATERIALS International Vol.29 No.4
Advanced automotive industries generate large demand for the next generation of high strength and high toughness springsteels. Vanadium-containing 55SiCrV spring steels subjected to rapid-induction heating treatment can fulfil such requirements. However, the effect of vanadium microalloying under online rapid-induction heat treatments is rarely reported. Acomparative study of the microstructure and tensile properties of 55SiCr and 55SiCrV spring steel wires subjected to a novelonline rapid induction heat treatment has been demonstrated herein. It is found that the tensile strength of the 55SiCr springwire decreases with the decrease in the wire speed in online rapid-induction heating, and the plasticity increases. Whereas,the tensile strength of the 55SiCrV steel wire increases with the decrease in the wire speed with the retained high plasticity,which is attributed to the strengthening effect of the dislocations. Through the optimized rapid-induction heating/coolingthermal cycles and intermediate-temperature tempering treatment, the tensile strength of the 55SiCrV steel wire approaches2106 MPa with total elongation of 9.7%. Compared with the 55SiCr spring steel, the addition of V in 55SiCrV spring steelchanges the strengthening and toughening mechanisms via the grain refinement and enhancement in the hardenability andtempering resistance. The finely dispersed V-containing secondary phases are rarely found in the matrix, which indicates thatthe precipitation effect stemming from the addition of V is not the dominant strengthening factor in the online rapid-inductionheat process. The proposed novel online rapid-induction heat treatment provides a promising pathway for the mechanicalproperty improvement of the spring steel.
Chuqian Lei,Ciqiu Yang,Bin Xia,Fei Ji,Yi Zhang,Hongfei Gao,Qianqian Xiong,Yufeng Lin,Xiaosheng Zhuang,Liulu Zhang,Teng Zhu,Minyi Cheng,Mei Yang,Kun Wang 한국유방암학회 2020 Journal of breast cancer Vol.23 No.1
Purpose: Tau is a microtubule-associated protein that can be found in both normal and abnormal breast cells. Whether the expression of Tau protein can predict the response to neoadjuvant chemotherapy (NACT) is still unclear. In this study, we assessed the role of Tau protein expression in predicting a pathological complete response (pCR) to NACT for different subtypes of breast cancer. Methods: Four hundred and sixty-eight eligible patients were retrospectively recruited in our study. The relationship between clinicopathologic factors, including Tau protein expression, and pCR in different subtypes was evaluated using logistic regression analysis. Correlation between Tau and disease-free survival (DFS) and overall survival (OS) was performed using Kaplan–Meier analysis. Results: The expression of Tau protein was negatively correlated with pCR, especially in triple-negative breast cancer (TNBC). No significant difference was observed in the luminal human epidermal growth factor receptor-2 (HER2)-negative subtype and HER2-positive subtype. Patients with pCR were associated with better DFS and OS (p < 0.05). However, Tau protein expression had no association with either DFS or OS (p > 0.05). Conclusion: Tau protein expression can predict pCR before NACT in TNBC, but there was no correlation between Tau expression and DFS or OS.
Discovery of nitrate–CPK–NLP signalling in central nutrient–growth networks
Liu, Kun-hsiang,Niu, Yajie,Konishi, Mineko,Wu, Yue,Du, Hao,Sun Chung, Hoo,Li, Lei,Boudsocq, Marie,McCormack, Matthew,Maekawa, Shugo,Ishida, Tetsuya,Zhang, Chao,Shokat, Kevan,Yanagisawa, Shuichi,Sheen, Nature Publishing Group, a division of Macmillan P 2017 Nature Vol.545 No.7654
Nutrient signalling integrates and coordinates gene expression, metabolism and growth. However, its primary molecular mechanisms remain incompletely understood in plants and animals. Here we report unique Ca<SUP>2+</SUP> signalling triggered by nitrate with live imaging of an ultrasensitive biosensor in Arabidopsis leaves and roots. A nitrate-sensitized and targeted functional genomic screen identifies subgroup III Ca<SUP>2+</SUP>-sensor protein kinases (CPKs) as master regulators that orchestrate primary nitrate responses. A chemical switch with the engineered mutant CPK10(M141G) circumvents embryo lethality and enables conditional analyses of cpk10 cpk30 cpk32 triple mutants to define comprehensive nitrate-associated regulatory and developmental programs. Nitrate-coupled CPK signalling phosphorylates conserved NIN-LIKE PROTEIN (NLP) transcription factors to specify the reprogramming of gene sets for downstream transcription factors, transporters, nitrogen assimilation, carbon/nitrogen metabolism, redox, signalling, hormones and proliferation. Conditional cpk10 cpk30 cpk32 and nlp7 mutants similarly impair nitrate-stimulated system-wide shoot growth and root establishment. The nutrient-coupled Ca<SUP>2+</SUP> signalling network integrates transcriptome and cellular metabolism with shoot–root coordination and developmental plasticity in shaping organ biomass and architecture.