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EPICS data acquisition system for FPGA-based plasma electron density measurement on KSTAR
Lee, Taegu,Kim, Myungkyu,Lee, Woongryol,Kwon, Giil,Tak, Taehyun,Juhn, Junewoo,Hong, Jaesic Elsevier 2018 Fusion engineering and design Vol.129 No.-
<P><B>Abstract</B></P> <P>The Korea Superconducting Tokamak Advanced Research (KSTAR) has several diagnostics devices, including a millimeter-wave interferometer (MMWI), far-infrared interferometer (FIR), two-color interferometer, etc., for measuring plasma electron densities. The MMWI diagnostic device measures the electron density of the plasma from the phase difference generated by transmitting a 1 mm (280 GHz) electromagnetic wave into it. The FIR device is similar to the MMWI, but uses a far-infrared (119 um) laser as its electromagnetic wave source. The MMWI is the primary plasma density measurement system in KSTAR. However, its signal contains significant noise and hundreds of fringe-jump events from the phase comparator circuit. The original analogue circuit of the phase comparator is limited in noise handling since it needs to average the raw IF signal to be treated in analogue circuit with limited bandwidth. To handle noise with more flexibility and to reduce occurrence of fringe-jump errors, we developed a new data acquisition (DAQ) system using a high-speed FPGA-based digitizer. The MMWI signal resembles a 10 MHz sine wave. We acquired data at 100 MSPS using a new digitizer. The phase difference per sample was 36°, which lead to inaccurate results due to noise. To increase the accuracy, the new DAQ system has interpolation logic within the FPGA that increases the phase resolution. In addition, the phase comparative value is transmitted to two channels by inverting the signal. The signal that does not travel through the plasma has a phase difference of 180°. The FPGA-based system was constructed using the same algorithm as existing phase comparator circuit []. The detected phase was averaged to obtain a phase value, and the result was transmitted as 1280 phase values per msec. In the EPICS Input/Output Controller (IOC), the density is calculated using data received from the direct memory access (DMA) via peripheral component interconnect (PCI) Express. The above FPGA logic was successfully used for real-time feedback control in the ITER CODAC environment. This paper introduces a new, detailed MMWI DAQ system design concept using FPGA, and its operational results.</P>
지관용 파이프절단기에서 개선을 고려한 절단궤적 관한 연구
이욱진(Wookjin Lee),김화일(Hwail Kim),이준우(Junewoo Lee),임근호(Geunho Lim),노태정(Taejung Lho) 대한기계학회 2009 대한기계학회 춘추학술대회 Vol.2009 No.5
The pipe coasters is applied to the shipbuilding equipment and heat exchanger that used in various fields. Faster than the existing methods and the process can be applied to following process, without postprocessing. Design equations of profiling shape and generates cutting path applicated 3-axises consists of a, X, and β-axis.
Bingkui Jin,Junewoo Lee,Seungan Kweon,Youngwoo Cho,Youngmi Choi,Sung Joong Lee,박영훈 한국원예학회 2019 Horticulture, Environment, and Biotechnology Vol.60 No.3
Fourteen watermelon cultivars with diff erent fruit fl esh colors (red, salmon yellow, orange, and canary yellow) were analyzedfor carotenoid contents (prolycopene, lycopene, β-carotene, ζ-carotene, and neoxanthin). Genes encoding the carotenoidbiosynthesis enzymes carotenoid isomerase (encoded by CRTISO ), which catalyzes the isomerization of prolycopene tolycopene, and β-carotene hydroxylase ( CHYB ), which catalyzes the conversion of β-carotene to xanthophyll, were alsoanalyzed. High-performance liquid chromatography showed that the salmon yellow and orange fl esh accumulated eitherprolycopene (orange-P fl esh) or β-carotene (orange-β fl esh), whereas lycopene and neoxanthin were the main carotenoids inthe red and canary yellow fl esh, respectively. Quantitative real-time polymerase chain reaction indicated that CRTISO andCHYB were mainly expressed during fruit maturation, regardless of the fl esh color, and there was no signifi cant associationbetween diff erential gene expression and fl esh color. Importantly, transcript sequencing revealed a non-synonymous singlenucleotidemismatch (T > C 1976 ) in exon 13 of CRTISO between orange-P-fl eshed and other cultivars, suggesting CRTISO asa candidate gene for high prolycopene accumulation. However, in β-carotene-accumulating cultivars, there were no mutationsin CHYB transcripts. A cleaved amplifi ed polymorphic sequence marker was developed for T > C 1976 , and its applicabilityfor marker-assisted selection of orange-P fl esh was validated in 105 watermelon accessions.
수박 엘리트 계통의 GBS를 통한 마커이용 육종용 SNP 마커 개발
이준우,손병구,최영환,강점순,이용재,제병일,박영훈,Lee, Junewoo,Son, Beunggu,Choi, Youngwhan,Kang, Jumsoon,Lee, Youngjae,Je, Byoung Il,Park, Younghoon 한국식물생명공학회 2018 식물생명공학회지 Vol.45 No.3
본 연구는 국내 육종 회사에서 개발된 수박(Citrullus lanatus L.) 우량 육성계통 20종을 대상으로 Genotyping-by-sequencing(GBS) 분석을 통해 품종식별, 순도검정, 그리고 마커이용여교잡(Marker-assisted backcross, MABC)용 SNP 세트를 개발하고자 수행되었다. GBS 분석 결과 총 1,100,000천개 raw read 중 77%가 수박 유전체에 mapping되었으며 평균 mapping region은 약 4,000 Kb로 2.3%의 genome coverage를 보였다. Filtering을 통해 평균 depth 31.57의 SNP 총 2,670개를 얻었으며, 20개 계통에 대한 이들의 Polymorphic information content(PIC) 값의 범위는 0.1 ~ 0.38 였다. 이 중 PIC 값이0.3이상이며 각 염색체 별로 5개씩 균등히 분포된 SNP 총 55개를 최종 선발하였다. 사용된 20개 계통의 유연관계분석을 위해 선발된 55개 SNP를 기반으로 한 주성분 분석(Principle component analysis, PCA) 결과 주성분 1 (52%)과 주성분 2 (11%)를 기준으로 4개의 그룹으로 분류 되었으며 각 계통 간 유전자형에 따른 뚜렷한 식별이 가능하였다. 계층적 군집화(Hierarchical clustering) 분석에서도PCA에서와 유사한 분류양상을 관찰할 수 있었다. 따라서 본 연구에서 개발된 SNP 세트는 적용 가능성이 검증된 20개 계통뿐 만 아니라 향후 다양한 수박 육종소재 및 품종에 대한 품종식별, F1 순도검정 및 MABC에 활용될 수 있으리라 기대된다. This study was conducted to develop an SNP set that can be useful for marker-assisted breeding (MAB) in watermelon (Citrullus. lanatus L) using Genotyping-by-sequencing (GBS) analysis of 20 commercial elite watermelon inbreds. The result of GBS showed that 77% of approximately 1.1 billion raw reads were mapped on the watermelon genome with an average mapping region of about 4,000 Kb, which indicated genome coverage of 2.3%. After the filtering process, a total of 2,670 SNPs with an average depth of 31.57 and the PIC (Polymorphic Information Content) value of 0.1~0.38 for 20 elite inbreds were obtained. Among those SNPs, 55 SNPs (5 SNPs per chromosome that are equally distributed on each chromosome) were selected. For the understanding genetic relationship of 20 elite inbreds, PCA (Principal Component Analysis) was carried out with 55 SNPs, which resulted in the classification of inbreds into 4 groups based on PC1 (52%) and PC2 (11%), thus causing differentiation between the inbreds. A similar classification pattern for PCA was observed from hierarchical clustering analysis. The SNP set developed in this study has the potential for application to cultivar identification, F1 seed purity test, and marker-assisted backcross (MABC) not only for 20 elite inbreds but also for diverse resources for watermelon breeding.
Jeong In Hwa,Kim Jong-Hun,Kwon Min-Jung,Kim Jayoung,Huh Hee Jin,Kim Byoungguk,Lee Junewoo,Nam Jeong-hyun,Kang Eun-Suk 대한의학회 2024 Journal of Korean medical science Vol.39 No.5
Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread globally, leading to the coronavirus disease 2019 (COVID-19) pandemic. Because a significant proportion of the COVID-19 confirmed cases were concentrated in the capital metropolitan area of South Korea, and a large proportion of the population in the area had been adequately vaccinated against COVID-19, we conducted a seroprevalence surveillance study focusing on the residents of the capital metropolitan area in South Korea. Methods: We used a quota-sampling method to obtain blood samples from 1,000 individuals per round, equally stratified across seven age categories and sexes and regions, from five medical institutions located within the capital metropolitan area of South Korea. During five consecutive months (rounds) between January 2022 and May 2022, a total of 5,000 samples were analyzed for anti-spike (S) and anti-nucleocapsid (N) antibodies. Results: High anti-S seropositivity was observed in all age groups, which corresponded to the vaccine coverage during the study period. Both the cumulative incidence based on polymerase chain reaction (PCR) and the estimated seroprevalence based on anti-N seropositivity increased in the fourth and fifth rounds, which corresponded to April 2022 and May 2022. Seroprevalence coincided with the cumulative incidence during the first three rounds, but exceeded from the fourth survey onwards when infection with omicron variants was increased rapidly in Korea. Conclusion: Seroprevalence confirmed the number of infection cases outside of PCR testing-based surveillance. Seroepidemiological surveillance can help us understand vaccine responses and detect hidden infections, thereby providing appropriate public health guidance for achieving population-level immunity.