위암 환자의 복강내 투여를 위한 Activated Charcoal-Alginate Bead 제형으로부터 Mitomycin C의 용출 거동

이진호,최선웅,서중기,김동민,정경수,오정연,김진향,노승무,민병무,김용백,김창식,박근성,강대영,송규상,양준묵,조준식,정현용,김학용,인현빈 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1

Locoregional recurrence is the most common type of recurrence in surgical operation of gastric adenocarcinoma, and peritoneal dissemination is one of the most difficult problems in advanced gastric adenocarcinoma treatment. Because the peritoneal cavity is the most common site of the first recurrence after gastric cancer resection, intraperitoneal chemotherapy seems a logical choice for cancer chemotherapy. In this study, Mitomycin C (MMC)-activated charcoal (CH)-alginate (ALG) beads were prepared by the mixtures of CH particles adsorbed with MMC as an anti-cancer drug and aqueous alginate solution. The alginate is recognized as biodegradable, nontoxic, and biocompatible. The release of MMC from the beads in 0.1 M Tris buffer was stable and continuous until about 1 week. The MMC-CH-ALG beads can be applied in the peritoneal cavity for intraperitoneal chemotherapy since they provide a good adhesiveness on the tissue and controlled release pattern of the drugs.

경막 내 colistimethate 투여로 치료한 다제 내성 cinetobacter baumannii 뇌실염

홍유아,유진홍,김진진,모은영,안건희,정희경,김진석,이현정,정미향,윤승배 대한감염학회 2009 감염과 화학요법 Vol.41 No.4

Acinetobacter species is a non-fermentative aerobic gram-negative coccobacillus that is an important pathogen found in nosocomial infections. Recently, multi-drug resistant Acinetobacter baumannii (MDR-AB) infections have been increasing and pose a serious problem. Most such infections present as bacteremia, pneumonia, or a wound infection; however, CNS infections are very rare. We herein present a case of ventriculitis caused by MDR-AB in a 37-year old man after a neurosurgical intervention. The patient was successfully treated with intrathecal colistimethate.

중학생들은 미쳤어! : 초기 사춘기에 대한 미국인들의 민속심리모델 The American Ethnopsychology of Early Adolescence

정향진 서울대학교 비교문화연구소 2002 비교문화연구 Vol.8 No.1

This paper examines the American cultural construction of emotions and its influences on the socialization of early adolescents. It is based on 12 months of ethnographic field research in a public junior high school in the Midwest, U.S. A child, according to the American cultural model of human development, goes through a series of distinctive stages as it matures, each stage being characterized by certain developmental features. With the stage model, early adolescence is readily conceptualized as a unique life phase, when the most observable and dramatic events of sexual maturation occur. The American educators associated early adolescence with a remarkably vulnerable emotional state, and explained the high emotionality in psychophysiological terms ("rmones" They conceived a major developmental difficulty of early adolescence as being too "otional"r "rational,"acking rationality ("ains on vacation" An urgent educational task was then to help early adolescents develop rational control over their emotions. Students were guided to verbalize and detach themselves from their emotions, especially when they experienced socially negative emotions, such as anger. This educational task was challenging, I contend, not so much because of the emotionality of early adolescents as the American cultural emphasis on emotion control.

사회관계망의 구조적 특성과 기능적 특성이 정신장애인의 사회적응에 미치는 영향

정선혜,이진향,서미경 대한신경정신의학회 2008 신경정신의학 Vol.47 No.2

Objectives : The purpose of this study was to investigate effects of structural and functional characteristics of social network on social adjustment in people with mental illness. Methods : 236 members of the people with mental illness who were enrolled in day hospital, community mental health center and social rehabilitation center participated in the survey. Results : Of structural and functional characteristics of social network, the influenced factors on social adjustment were network size of professional, social support (family, friend and professional) and conflict with professional. When controlling socio-demographic and disorder characteristics, this regression model affected significantly on social adjustment but the power of influence reduced slightly. Conclusion: In order to improve the social adjustment of people with mental illness, it is necessary for social network to provide them with more emotional and social resources. Especially, it is important for mental health professionals to build active partnership with the people with mental illness as consumer. For people with mental illness, the economic stability through guaranteed income such as disability benefits, and occupational rehabilitation is very important.

사용자 수술명과 수술분류 code(ICD-9-CM) 일치율 향상에 관한 연구 : 수술실 OCS program 사용 활성화를 통하여

최향하,김미영,김도진,유지원,장정화,박수정,박재성 한국의료QA학회 2005 한국의료질향상학회지 Vol.12 No.1

Background : The necessity of unify and standardize codes used at hospital has been emphasized since OCS (Order Communicating System) was adopted. Therefore, the purpose of this study were to standardize operation code by continuous training of the ICD-9-CM code that is used as standard code in OCS program at operating room. Method : In 400 operation data, operation code entered in OCS program at operating room was compared to operation name recorded in medical record. In addition, a matching rate between input data of operation code by medical record department and computing input data of operation code in 3,710 cases was compared for each department. User operation name and operation code were matched and major diagnosis by operation department and operation name were also matched. Results : User operation name was reflected in operation classification code in detail, and operation code entered on user was registered. Input rate and matching rate of operation code were gradually improved after improvement activity. In particular, a matching rate was high at ophthalmology where operation name is segmented. Plastic surgery and orthopedics with a lot of emergency operation and comprehensive operation name show low input rates. Conclusions : As the medical field makes progress in computerlization, awareness of information exchange and sharing becomes higher. Among codes to classified medical institution, codes related to surgical operation are all different by user of hospital and department. Computerlization and standardization is essential. And when efforts of standardization continue in alliance with individual hospital and institution, initiative of preparing medical policy data at a national level will be accelerated.

무우자갈버섯(Hebeloma crustulineforme)을 위시한 한국산 담자균류 46종의 용혈활성 검색

양희정,정수현,김진향,정경수 충남대학교 약학대학 의약품개발연구소 1997 藥學論文集 Vol.13 No.-

To elucidate the hemolytic toxicities of Korean basidiomycetes, the cold-water extracts of 46 wild mushrooms were tested for hemolytic activity on mouse erythrocytes. Twelve species including Amanita esculenta, A. griseofarinosa, A. longistriata, A. melleicepe, A. phalloides, A. rubescence, A. spissacea, A. vaginata, Hebeloma crustuliniforme, Lepiota cygnea, Macrolepiota procera, and Oudemansiella platyphylla showed strong hemolytic activities. Of these, A. griseofarinosa and H. crustuliniforme showed no decrease in their hemolytic activity even after five minutes' boiling.

정지영상 압축을 위한 이진적응에 관한 연구

김향태,위승정,정재영,최호진,최봉한,이웅기 조선대학교 통계연구소 1999 統計硏究所論文誌 Vol.1 No.1

대용량 저장장치의 출현, 컴퓨터 성능 및 초고속 망의 급속한 성장, 디지털 필름스캐너의 성능 향상 및 비용 감소 덕분에 디지털 형태로 영상을 다루기 위한 요구가 점차 증대되는 추세이다. 디지털 영상은 항상 고품질을 유지해야 하므로 화소 당 비트를 높게 할당하는데 이때 소요되는 방대한 비트 수를 효과적으로 감소시켜 저장용량 및 대역폭을 줄이기 위해서는 효율적인 영상 압축이 요구된다. 본 눈문은 디지털 영상의 압축을 위한 새로운 이진적응 방식을 제안한다. 먼저 변환된 예측오류를 얻기 위해 적응예측을 하고, 모델 템플리트로부터 적당한 예측오류 값 영역을 하나의 context영역이 되도록 하는 방식으로 부호화에 적절한 수의 context 영역을 결정한다. 그리고 부호화 효율을 개선하기 위해 개별적인 context 영역에서 부호화 될 예측오류가 나타날 확률을 근접하게 추정한 후, 고 빈도 예측 심볼 집합을 이진적응에 적용하여 부호화의 효율을 개선한다.

영지버섯 생장점 단백다당체 GLB의 대식세포 활성화 효과

오정연,조경주,정수현,김진향,Lillehoj, H.S.,정경수 충남대학교 약학대학 의약품개발연구소 1998 藥學論文集 Vol.14 No.-

In the previous study we described the antitumor activity of GLB. a protein-polysaccharide fraction of the growing tips of Ganoderma lucidum, against sarcoma 180 solid tumor in ICR mice. In this study we investigated the stimulatory activity of GLB on macrophages. When analyzed using a flow cytometer. GLB (100 ㎍/㎖) was found to increase the phagocytic activity of the BALB/c mouse peritoneal macrophages as well as chicken macrophage BM2CL cells against FTTC-labeled C. albicans by 55.2% and 21.2%, respectively. GLB also increased the spreading and the expression of MHC class Ⅱ molecules of BM2CL cells as well as the mouse peritoneal macrophages. From these results, it is clear that GLB is a strong stimulator to the macrophages.

인터랙티브 광고의 효과에 관한 연구 : 텔테프레즌스의 수용자변인을 중심으로

탁진영,박정향 한국방송광고공사 2005 광고연구 Vol.0 No.68

본 연구의 목적은 인터넷 광고연구의 연장선상에서 텔레프레즌스를 중심으로 한 인터랙티브광고의 효과를 실증적으로 살펴보고, 인터랙티브 미디어 광고의 활용방안 등을 검토해 보는데 있다. 따라서, 본 연구는 수용자들이 경험하는 텔레프레즌스의 선행변인들 중 수용자변인을 중심으로 살펴보고, 이러한 요인들에 의해 생성된 텔레프레즌스의 경험이 인터랙티브 광고효과에 어떠한 영향을 미치는 지를 살펴보았다. 본 연구의 결과를 종합하면, 인터랙티브광고에 대한 관여도가 높고, 소비자의 사용기술 정도가 높을수록 텔레프레즌스의 경험정도가 높아진다는 것이 통계적으로 유의미하게 나타난 반면, 소비자의 몰입경향은 텔레프레즌스 경험정도에 영향을 미치지 않는 것으로 나타났다. 또한, 본 연구에서는 소비자들이 인터랙티브 광고에 있어 텔레프레즌스의 경험정도가 높을수록 웹사이트에 대한 태도, 브랜드에 대한 태도가 더 호의적으로 나타나고, 재방문 의사도 더 높게 나타났다. 인터랙티브 광고에 있어서 웹사이트에 대한 태도와 브랜드에 대한 태도가 호의적일수록 재방문 의사가 높게 나타났다. 한편, 텔레프레즌스가 재방문 의사에 미치는 효과계수를 살펴본 결과, 텔레프레즌스가 재방문 의사에 미치는 직접적인 효과보다는 웹사이트에 대한 태도 및 브랜드에 대한 태도를 거쳐서 재방문 의사에 영향을 미치는 간접적인 효과가 더 크게 나타났다. 아울러, 연구의 한계점과 후속연구를 위한 제언을 제시하였다. The purpose of this study was investigating the influences of interactive advertising focusing on Telepresence experience of audiences and proposing practical strategies for interactive advertising. Reviewing various preceeding variables of user experience, this study tried to empirically test the effects of Telepresence experience on interactive advertising with the audience variables. The results showed that audiences with the higher involvement on interactive advertising and the more skills about computer technology of interactive advertising indicated stronger Telepresence experience rates. However, audiences' immersive tendency toward stimulus resulted in low effects on Telepresence experiences of audience. The results also revealed that if the users had higher experience rate of Telepresence, they tended to have more favorable attitudes toward the web site and the brand. Further, this higher rate of Telepresence led the audience to higher intentions to revisit the web site. Finally, the effect coefficient of Telepresence variable on intention to revisit the web site also indicated that indirect effects via attitudes toward the web site and the brand was bigger than direct effects of Telepresence.

호텔고객의 참여에 따른 기능적 서비스와 고객만족간의 관계

허향진,정영림 濟州大學校 社會發展硏究所 2003 社會發展硏究 Vol.18 No.-