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김종해,이동헌,이철우,김중기,김동희,조규판 嶺南大學校 工業技術硏究所 1998 工業技術硏究所論文集 Vol.26 No.2
This paper proposes a double resonant high frequency inverter which reduces the distribution of the switching current. The analysis of the proposed circuit is generally described by using the normalized parameters. Also, the principle of the basic operation and the characteristics of driving were estimated by the switching frequency and the load parameters. And the data for the design were got by the characteristic values obtained from the characteristic estimation. At the same time the example of the design method was proposed. In addition, Comparing the theoretical waveforms to the experimental waveforms certified the operating characteristics of the proposed Inverter. It is certain that the proposed circuit will be used and expanded in the high frequency power supplies like induction heating systems.
알루미늄 합금과 고장력 강판 접합을 위한 헬리컬 SPR의 단조공정 설계
김원영, 김동범, 김기호, 김도훈, 이인환, 조해용 충북대학교 산업과학기술연구소 2013 산업과학기술연구 논문집 Vol.27 No.2
A self-piercing rivet(SPR) is a mechanical component for joining dissimilar materials. It is used for joining dissimilar material sheets such as aluminum alloy and steel. The self-piercing rivet directly pierces into sheets without drilling sheets beforehand unlike conventional rivets. However, the self-piercing rivet occurs buckling when piercing high strength steel. Therefore, a helical SPR which can pierce high strength steel sheet was designed. In this study, forging process was designed for manufacturing the helical SPR and simulated by using commercial FEM code DEFORM-3D. In the simulation of forging process for manufacturing rivet, process sequence, formability, forging load were investigated. The suitable forging process could be designed by comparisons of simulated results. Experimental trials have been carried out for same conditions as simulated ones. The simulated results agreed with the experimental ones. So, the analytic approach in this thesis is useful to save cost and time in the forging industry
임종한,장성실,김성아,문재동,채창호,홍윤철,김수영,김진석,김영욱,한상환,이혜숙,원종욱,송동빈,하은희,강성규 대한산업의학회 2001 대한직업환경의학회지 Vol.13 No.2
기존의 특수건강진단과 작업환경측정을 통한 직업병 관리가 진폐증, 소음성난청 등의 소수 특정질환에 국한되고 실제 직업병 발생 규모 파악이나 신종 직업병의 발견에 한계를 보인다는 사실은 산업의학전문가들 사이에서도 공감을 이루고 있다. 미국과 영국 등에서의 직업성질환 감시체계에 대한 경험은 우리 나라의 직업성질환 감시체계 구축에도 새로운 자극제가 되면서, 1998년이후 인천, 대전, 여천, 구미, 부울경 지역에서 지역 직업성질환감시체계를 산업보건관리의 중요한 시스템으로 구축하려는 노력이 확산되고 있다. 새로이 구축되어지는 이들 지역 직업성질환 감시체계는 감시하고자 하는 대상질환, 활용 가능한 인적자원 및 자료원, 지역 의료체계의 특수성 등에 따라서 목적과 방법을 달리하면서 독특한 형태로 발전을 하고 있다. 각 지역단위 감시체계들이 그 상황에 맞게 독특한 목적과 전략들을 발전 시키면서도, 향후 발전할 국가적인 차원의 직업성질환 감시체계 구축을 위하여 직업성질환 감시의 기본 전략 등을 공유하는 등의 노력이 필요하다. 환례 정의 및 기본적인 등록 서식의 공유, 직업성질환 감시 자료원의 발굴, 공동의 정보 네트워크 및 직업성질환 감시 데이터베이스 구축 등 직업성질환 감시활동을 지원하기 위한 여러 기초 인프라 구축에 힘을 모아야 할 것이다. 우리 나라에서 직업성질환 감시체계를 성공적으로 구축하기 위해서는 수집된 자료의 질 관리를 위한 직업성질환 감시의 원칙 제정과 감시 전략의 공유 등이 필요하며, 전국적인 직업성질환 감시체계의 하부구조라고 할 수 있는 지역감시체계의 기초 토대 마련과 강화작업이 절실하게 필요하다.
Lee, Dahae,Lee, Dong-Soo,Jung, Kiwon,Hwang, Gwi Seo,Lee, Hye Lim,Yamabe, Noriko,Lee, Hae-Jeong,Eom, Dae-Woon,Kim, Ki Hyun,Kang, Ki Sung The Korean Society of Ginseng 2018 Journal of Ginseng Research Vol.42 No.1
Background: The aim of the present study was to evaluate the potential protective effects of six ginsenosides (Rb1, Rb2, Rc, Rd, Rg1, and Rg3) isolated from Panax ginseng against tacrolimus (FK506)-induced apoptosis in renal proximal tubular LLC-PK1 cells. Methods: LLC-PK1 cells were treated with FK506 and ginsenosides, and cell viability was measured. Protein expressions of mitogen-activated protein kinases, caspase-3, and kidney injury molecule-1 (KIM-1) were evaluated by Western blotting analyses. The number of apoptotic cells was measured using an image-based cytometric assay. Results: Reduction in cell viability by $60{\mu}M$ FK506 was ameliorated significantly by cotreatment with ginsenosides Rg1 and Rb1. The phosphorylation of p38, extracellular signal-regulated kinases, and KIM-1, and cleavage of caspase-3, increased markedly in LLC-PK1 cells treated with FK506 and significantly decreased after cotreatment with ginsenoside Rb1. The number of apoptotic cells decreased by 6.0% after cotreatment with ginsenoside Rb1 ($10{\mu}M$ and $50{\mu}M$). Conclusion: The antiapoptotic effects of ginsenoside Rb1 on FK506-induced apoptosis were mediated by the inhibition of mitogen-activated protein kinases and caspase activation.
개원의의 진료의뢰시 기대요인 및 만족도에 관한 연구 : 협력병원체제 여부를 중심으로
김동일,김해준,윤석준,문영배 한국의료QA학회 2002 한국의료질향상학회지 Vol.9 No.2
Background : This research, as a part of improving management process of college hospital in this rapidly changing circumstances, is searching for the actual state of private clinics referring patients to referral center including college hospitals. Methods : This research examined the sense of satisfaction and requesting degree in using referral center and by analyzing the correlation and differences among factors such as primary factors regarded as selecting ones in referring patients to a referral center in college hospital and expecting factors expected to be supported to patients and cooperative hospitals. Results : The main researched results are as follows. First, as for the primary factors, the differences between cooperative and uncooperative hospitals revealed the fact that choosing target hospital in accordance with cooperative relation and convenient process in referring patients are important. Second, satisfaction rates, analyzed from the paired t-test revealed kindness and convenience as the top priorities, while sending patients back again and benefit of supporting such as the use of facilities were revealed as the least satisfactory aspects, despite the fact that they should be fulfilled through actual service. Conclusion : The recognition of the practitioner is examined and analyzed in this research by examining primary factors in selecting college hospitals, expecting factors expected to be supported to patients and satisfaction degree, which are expected to be used as basic materials for the development of referral center of college hospitals.
노인인구에서 ApoE 유전자형에 따른 머리둘레와 인지기능간의 연관성
김경란,오병훈,이준영,김은아,정해관,이동우,홍창형 大韓神經精神醫學會 2007 신경정신의학 Vol.46 No.3
Objectives : The aim of this study is to find out the effect of ApoE genotype on correlation between head circumference and cognition of the elderly in the community. Methods : A total of 1,152 subjects (380 men and 772 women) aged 60-91 years were analyzed from preliminary data of GDEMCIS (Gwangju Dementia and MCI Study). The study questionnaire consisted of demographic characteristics, current and past illness history, drug history and K-MMSE (Korean version-Mini Mental State Examination). We also measured the head circumference and examined ApoE genotype. Results : On regression analysis, as head circumference becomes smaller, K-MMSE scores decreased adjusted by age, sex, educational level, ApoE ε4 allele, current smoking and alcohol drinking status (β=0.15, P=0.04). Only in the lowest qu-artile group, presence of ApoE ε4 allele reduced K-MMSE scores adjusted by age, sex, educational level, height, current alco-hol drinking and smoking status (β= -1.39, P= 0.008) Conclusion : These results suggest that head circumference may have an influence on K-MMSE scores, and presence of ApoE ε4 allele may be a medicating factor.
커패시터 공진전압을 이용한 하프 브릿지 고주파 인버터의 특성해석에 관한 연구
김동희,김도선,김종해,노채균 嶺南大學校 工業技術硏究所 1997 工業技術硏究所論文集 Vol.25 No.2
This paper presents operating characteristics of the main conversion considering half-bridge high frequency resonant inverter using capacitor Resonant voltage to the object of research. The analysis of the proposed circuit describes generally by using normalized parameter, and basic operating principle and driving characteristics have been evaluated as to switching frequency and load parameter. Several features are considered, this paper suggests some fundamental data for designing the main power conversion circuit. To prove rightfulness for characteristics analysis of proposed inverter, it is confirmed that this paper are nearly, equal to circuit analysis by comparison theoretical and experimental waveforms results of proposal inverter using Power-MOSFET of switching devices. In the future, design technique proposed in this paper can be applied to several areas such as induction heating, power supply of DC-DC converter, UPS etc.