Demixing the Miscible Liquids: Toward Biphasic Battery Electrolytes based on the Kosmotropic Effect

김원영,김홍이,이상영 한국고분자학회 2024 한국고분자학회 학술대회 연구논문 초록집 Vol.49 No.1

Extended Use of Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome: A Retrospective Multicenter Study

김원영,박승용,김화정,백문성,정치량,박소희,강병주,오진영,조우현,심윤수,조영재,박성훈,김정현,홍상범 대한결핵및호흡기학회 2019 Tuberculosis and Respiratory Diseases Vol.82 No.3

Background: Beyond its current function as a rescue therapy in acute respiratory distress syndrome (ARDS), extracorporeal membrane oxygenation (ECMO) may be applied in ARDS patients with less severe hypoxemia to facilitate lung protective ventilation. The purpose of this study was to evaluate the efficacy of extended ECMO use in ARDS patients. Methods: This study reviewed 223 adult patients who had been admitted to the intensive care units of 11 hospitals in Korea and subsequently treated using ECMO. Among them, the 62 who required ECMO for ARDS were analyzed. The patients were divided into two groups according to pre-ECMO arterial blood gas: an extended group (n=14) and a conventional group (n=48). Results: Baseline characteristics were not different between the groups. The median arterial carbon dioxide tension/ fraction of inspired oxygen (FiO2) ratio was higher (97 vs. 61, p<0.001) while the median FiO2 was lower (0.8 vs. 1.0, p<0.001) in the extended compared to the conventional group. The 60-day mortality was 21% in the extended group and 54% in the conventional group (p=0.03). Multivariate analysis indicated that the extended use of ECMO was independently associated with reduced 60-day mortality (odds ratio, 0.10; 95% confidence interval, 0.02–0.64; p=0.02). Lower median peak inspiratory pressure and median dynamic driving pressure were observed in the extended group 24 hours after ECMO support. Conclusion: Extended indications of ECMO implementation coupled with protective ventilator settings may improve the clinical outcome of patients with ARDS.

Epinephrine 후안구 투여 후 발생한 가역적 심근증 1예

김원영,김원,이재호,조규종,홍정석,안신,임경수 대한응급의학회 2002 대한응급의학회지 Vol.13 No.4

Catecholamine induced cardiomyopathy is well known in pheochromocytoma, subarachnoid hemorrhage patients and in patients who received with large amount of exogenous catecholamine for therapeutic use. Few cases have been reported after short time exposure of excessive exogenous catecholamine. Furthermore only one case has been reported after clinically relevant dose of exogenous catecholamine in Japan. We describe a 38-year-old female presented as chest pain and presyncope after retrobulbar injection of a small dose epinephrine for opthalmologic surgery. The echocardiography and the cardiac specific enzyme of her demonstrated cardiomyophthy. Her cardiac funcion was nearly normalized after dopamine and dobutamine therapy. We report a case of cardiomyopathy induced by a clinical acceptable dose of retrobulbar epinephrine injection in a patient with no evidence of heart disease.

지하수 추출에 의한 지반침하 중국의 예

김원영 대한지질공학회 2014 대한지질공학회 학술발표회논문집 Vol.2014 No.-

지르코니아 코핑과 전장도재 간의 전단결합강도와 파절양상 비교

김원영,전병욱,정인성 대한치과기공학회 2015 대한치과기공학회지 Vol.37 No.4

Purpose: The aim of this study was to investigate the shear bond strength between various commercial zirconia coping and veneering ceramic, and to observe the failure mode. Methods: For each zirconia block (iJAM Emerald, LUXEN Smile block, ICE Zirkon transluzent), 10 rectangular specimens were layered with Cercon ceram kiss, IPS e.max ceram, ICE Zirkon ceramic according to recommended by the manufacturer. The shear bond strength tests of the veneering porcelain to zirconia were carried out until fracture by a universal testing machine. After the shear bond tests, failure modes were characterized visually, under a stereomicroscope, such as adhesive, cohesive, or mixed. Data were analyzed with One-way ANOVA followed by Scheffe's tests. Results: The shear bond strength (mean±SD) of zirconia-veneer ceramic were JC group 13.9±3.6 ㎫; JE group 17.7±2.4 ㎫; JI group 15.1±2.5 ㎫; LC group 9.5±1.5 ㎫; LE group 16.2±2.3 ㎫; LI group 12.6±0.8 ㎫; ZC group 16.0±2.3 ㎫; ZE group 18.5±3.4 ㎫; and ZI group 15.3±3.2 ㎫. The One-way ANOVA showed a significant difference between groups (p<0.05). The failure mode in most experimental groups was mixed failure, except for the LC group, which showed adhesive failure, and JE group, LE group and ZE group showed cohesive failure. Conclusion: For IPS e.max ceram, the shear bond strength value was highest for all kinds of zirconia blocks. For ICE Zirkon transluzent, the shear bond strength value was highest for all kinds of veneering ceramics. Most of experimental group interfaces revealed mixed failure mode.

소장점막의 허혈-재관류 손상에 대한 Capsaicin의 보호효과

김원영,임경수,박형섭 대한응급의학회 2002 대한응급의학회지 Vol.13 No.2

Purpose: Capsaicin, a major ingredient of hot peppers, has a stimulatory effect of the neurons. Ingested capscaicin causes pain and even damages the mucosa with a large dose. On the other hand, it protects the gastric mucosa against many ulcerogenic agents or conditions. In this study, we investigated the effect of oral capsaicin on the ischemia-reperfusion damage of the intestinal mucosa in rats. The involvement of stress proteins such as HSP-70 and HSP-72 in the action of capsaicin was also investigated. Methods: Male Sprague-Dawley rats were given oral capsaicin (20 mg/kg/day) for a designated period. Ischemia of the small intestine was inflicted by clamping the superior mesenteric arteries for 30 minutes under anesthesia. After the ischemic period, the clamp was released and the animal was kept for 1,5, or 24 hours. Then, the intestinal structure was observed under the microscope, and the levels of the heart-shock proteins were determined by using a Western blot. Results and Conclusion: Oral capsaicin protected the mucosa of the small intestine against the ischemia/reperfusion injury. Capsaicin also increased and expedited the ischemia/reperfusion-induced expression of the heat-shock proteins, HSP-70 and 72, in the intestine. The possible linkage between the two events is discussed.

野球競技에서 Base Running에 關한 硏究 : 打者走者 二壘進壘의 效果的인 Course選擇을 中心으로

金元永,金鼎柱,金尙國 경희대학교 체육과학연구소 1985 體育學論文集 Vol.13 No.-

To investigate the time, the distance and the number of steps along different courses of 'base-running,' some players of amateur base-ball teams were made objects of this investigation and the conclusion reached is as follows: 1.The necessary times for running are 8"00 along A Course, 7"92 along B Course and 7"80 along C Course respectively. C Course turns out to require the minimum of time. 2.The numbers of steps are 34.7 paces along A Course, 34.6 paces along B Course and 34.8 paces along C Course respectively. 3.The distance are 55.85m along A Course, 55.54m along B Course and 56.34m along C Course respectively. C Course turns out to be the longest. 4.The angle of the change of direction from first base to second base is 50˚ along each course. But C Course, whose angle of advance from uome base to first base is little and that from first base to second base is great, turns out to be one along which the runner can run in the least time. (Fig. 1 Refer to the angle of the change of direction along each course.) Along C Course, the runner can minimize, when he changes his direction, the centrifugal force caused by acceleration, and make the best of the acceleration. Therefore, C Course is the most desireable.

Comparable efficacy of tigecycline versus colistin therapy for multidrug-resistant and extensively drug-resistant Acinetotbacter baumannii pneumonia in critically ill patients

김원영,문재영,허진원,임채만,고윤석,정용필,홍상범 대한결핵 및 호흡기학회 2015 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.120 No.-

Background: Tigecycline may be an alternative therapy of treating pneumonia caused by multidrug-resistant and extensively drug-resistant Acinetobacter baumannii (MDR/XDRAB). The aim of this study was to compare the efficacy of tigecycline-based therapy with colistin-based therapy in patients with MDR/XDRAB pneumonia. Methods: Between January 2009 and December 2010, patients in the intensive care unit who were diagnosed with MDR/XDRAB pneumonia and treated with either tigecycline or colistin mono-/combination therapy were reviewed. Results: A total of 70 patients were included in our analysis. Among them, 30 patients received tigecycline-based therapy, and 40 patients received colistin-based therapy. Baseline characteristics were similar in the two groups. The 30-day mortality was 33% in the tigecycline group and 30% in the colistin group (P = 0.77). Colistin-based therapy was significantly associated with developing nephrotoxicity (P = 0.009). Microbiological failure, clinical failure, and mortality rates were numerically lower in the combination therapy than in the monotherapy. Multivariate analysis indicated that monotherapy was independently associated with increased clinical failure (aOR, 4.35; 95% CI, 1.05 to 18.02; P = 0.04). Conclusions: Our results suggest that tigecycline-based therapy was tolerable and the clinical outcome was comparable to that of colistin-based therapy for patients with MDR/XDRAB pneumonia. In addition, combination therapy may be more useful than monotherapy in treatment of MDR/XDRAB pneumonia.

범하수체 기능저하증을 동반한 일차성 중추성 림프종의 1예

김원영,김원,조규종,홍정석,이미우,장성은,오세현,임경수 대한응급의학회 2001 대한응급의학회지 Vol.12 No.4

A primary central nervous system lymphoma(PCNSL) is defined as a lymphoma limited to the cranial-spinal axis without systemic involvement. PCNSLs were formerly very rare, only 0.5∼ 1.2% of all intracranial neoplasms, and were usually associated with acquired immuno-deficiency syndrome(AIDS) and other immune-compromised states. Recently, there has been a clear rise in the incidence of this disease among normal individuals. We describe a 77-year-old female with hyponatremia who presented with a confused mental state. Computed tomography(CT) of the brain demonstrated a suprasellar mass with enhancement. We evaluated the basic hormonal studies and the magnetic resonance imaging(MRI). A ventricular biopsy was done, and the result was a diffuse, large, B-cell-type malignant lymphoma. She presented panhypopituitarism and partial central diabetes insipidus. She received chemotheraphy and was discharged in an improved condition. We report a case of panhypopituitarism due to PCNSL and give a review of the literature.

지진 유발 산사태 특징

김원영 대한지질공학회 2015 대한지질공학회 학술발표회논문집 Vol.2015 No.2