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      • 갑상선 유두암이 병발된 가족성 대장 용종증 1예

        백종현,소창배,이은영,이지숙,신은경,박은호,서정아,양재홍,송준영,박선자,박요한,최영식 고신대학교의과대학 2007 고신대학교 의과대학 학술지 Vol.22 No.2

        Familial adenomatous polyposis (FAP) is an autosomal dominant syndrome, typically characterized by multiple colorectal adenomas and increased incidence of colorectal carcinomas if it is not treated. Moreover, a variety of extracolonic manifestation are seen. The prevalence of thyroid tumors developing in patients with FAP is about 1∼2%. Generally, papillary thyroid cancer indicates low mortality but ,however, as people get older, the cancer becomes more aggressive. So, the operation is required. Recently we experienced a case of FAP, presenting with papillary thyroid carcinoma, and reported with a brief review of literatures.

      • 유아 매스미디어에 대한 분석

        박유미,김은아,서명숙 원광대학교 2006 論文集 Vol.37 No.-

        This research is aimed to know how educating mass media to children has impacted on child-development by analyzing some data studied through. We suggested some questions for this conducting. First, what is the point issued by early media use to children? Second, How much has the study about children's computer use been done? We have drawn these conclusions. About the first question, early educators had pro and con to the media use and they had focused on popularity and use of new media. And then they have changed their focus to some effects or impacts of new media on child-development. For the second question, in our country as well as other countries, there have been some meaningful effects, a few negative sides and none effects to child-development. On the ground of education, the computer use has been adapted and applied to child-development with proper softwares fitted good topic or intention. Besides, many teachers have tried to have good interactions with their young students. But we are insisting one thing that more chances to make use of computer be given to young students at home and there be more connections between two educational fields- home and school.

      • KCI등재

        예비유아교사의 사회적 연결망과 학업 성취 및 자기 효능감과의 관계

        박은혜,김언아 이화여자대학교 교육과학연구소 2001 교육과학연구 Vol.32 No.1

        본 연구는 예비유아교사들이 형성한 사회적 연결망이 그들의 학업 성취 및 자기 효능감과 어떠한 관계를 가지고 있는지를 알아보기 위하여 실시되었다.이를 위하여 사립 4년제 대학 유아교육과에 재학하고 있는 109명의 학생을 대상으로 이름 기술 질문과 자아효능감 척도 설문지를 활용하였다.연구결과 예비유아교사들의 학습연결망은 학업 성취도와 높은 상관을 보였으나 여가 연결망이나 고민 상담 연결망은 낮은 상관을 보였다.반면 예비유아교사들의 자아효능감은 여가연결망 및 고민 상담 연결망과 상관관계를 보였다. The purpose of this study is to see if there is any relation, and, if any, to pursue what kind of relation is, between pre-service teachers' social network and their learning achievement and self efficiency.For this purpose, three questions have been set up as follows: 1.Does the pre-service teachers' social network have any relation to their learning achievement? 2.Does the pre-service teachers' social network have any relation to their self efficiency? One hundred and nine woman collegians except freshmen were selected for the survey of this study.They are now registered in the department of early childhood education in the teachers' college of a private university.To examine the social network, Scott's Name Generator Question(NGQ) was used as a tool.To look into self efficiency, Kim's Measurement of Self-efficiency(1997) was used for a study tool.In the process of analyzing the data, 4.2 version of 'Structure' and SPSS(for Window) statistics program were used in dealing with frequency, descriptive statistics, Pearson's correlation, one-way ANOVA.The results of this study are as follows: pre-service teachers' studying network which consists of social network along with leisure network and counseling network is closely related to their learning achievement but is barely related to their self-efficiency.First of all, pre-service teachers who are most frequently selected by their friends get higher GPA score than the others, and those who have contact efficiency also get better score.But those who belong to close-network circle because of high density in studying network and are in network-constraint get lower GPA score.Consequently the pre-service teachers who attain prominence for being more frequently selected by their friends get higher score. On the other hand, pre-service teachers' leisure network is highly related to their self-efficiency, while it has no relationship to their learning achievement.In the leisure network, being selected by many friends is closely related to self confidence and self-reguratory efficiency among the sub-scales of self-efficiency.Pre-service teachers' counseling network is relationship to their learning achievement about prominence in network.And pre-service teachers' counseling network is relationship to their self-efficiency.Most of all, the contact efficiency in network is close relationship to their self-efficiency.If some pre-service teachers have high density and much constraint in counseling network, they belong to close-network circle.So they have very low self-efficiency.

      • KCI등재후보
      • 집합주거단지의 치유조경 계획요소에 관한 연구

        이은엽, 박진아, 심준영, 이시영 배재대학교 자연과학연구소 2014 自然科學論文集 Vol.25 No.1

        본 연구는 집합주거를 대상으로 그 외부공간에 치유환경을 제공하고자 함이 궁극적 목표이며, 본 연구는 그 이전에 치유환경설계에 앞서 치유정원의 환경적 특성과 치유정원의 계획요소를 밝히고자 한다. 본 연구를 통해 치유공간계획을 위한 기초적 지침을 제시하고자 한다. 연구방법으로서, 기존 학자들의 치유정원에 관한 특성을 분석하여 공통적인 환경특성 요소들을 도출하고, 이를 바탕으로 국내·외의 문헌을 참조하여 세부항목을 설정하고 치유정원의 특성을 파악하였다. 치유정원의 계획원칙 및 요소를 도출하기 위해 문헌조사와 전문가의 의견을 취합하여 공동 집합 주거단지에 적용 가능한 조경계획요소를 설정하였다. 치유환경의 환경특성의 계획요소는 총 6가지의 항목을 설정하였다. 안전한 환경, 치료적 환경, 보조적 환경, 지남력 강화환경, 쾌적성, 사회적 환경으로 구분하였다. 계획원칙으로는, 안전감, 이용자 그룹과 요구에 대한 인식, 다양한 활동패턴의 제공, 다양하게 경험할 수 있는 치유공간, 휴식과 활동공간에 대한 특성부여, 사적공간과 사회적 교류, 주변환경과 전망, 유니버셜 디자인, 셉테드 디자인으로 구분하였다. The purpose of this study is to figure out planning guidelines and environmental characteristics of healing garden for providing healing surroundings on outdoor spaces of multiple housing complex. To do this, this study examined previous research papers and scholastic writings, related to healing environment and garden, and analyzed case studies. As a result, composition elements of planning for healing garden were classified 6 types; safe, therapeutic, assistance, orientation strengthen, comfort and social environment. Planning principles of healing landscape are set for 9 types; sense of safe, recognition of the user group and demand, offers a variety of activity patterns, healing space for various ways to experience, characteristics for relaxation and activities, private space and social interaction, surroundings and views, universal design and cpted design. From the precedent review and literature view planning guidelines for creating healing gardens will be created. These guidelines will then be applied to an existing healing site to create an informed design solution.

      • KCI등재

        아마릴 정(글리메피리드 2㎎)에 대한 글리메드 정의 생물학적 동등성

        조혜영,박은자,강현아,백승희,이석,김세미,문재동,이용복 한국약제학회 2004 Journal of Pharmaceutical Investigation Vol.34 No.2

        The purpose of the present study was to evaluate the bioequivalence of two glimepiride tables, Amaryl^(?)(Handok/Aventis Pharm. Co., Ltd.) and Glimed (Kuhn Ⅱ Pharm. Co., Ltd.), according to the guidelines of Korea Food and Drug Administration (KFDA). The glimepiride release from the two glimepiride formulations in vitro was tested using KP Ⅷ Apparatus Ⅱ method with a variety of dissolution media (pH 1.2, 4.0, 6.8 buffer solution, water and blend of PSB 80 into each dissolution medium). Twenty six healthy male subjects, 22.65±2.19 years in age and 66.55±8.85 kg in body weight, were divided into two groups and randomized 2×2 cross-over study was employed. After one tablet containing 2 ㎎ as glimepiride was orally administered, blood was taken at predetermined time intervals and the concentrations of glimepiride in serum were determined using HPLC method with UV detctor. The dissolution profiles of two formulations were similar at all dissolution media. Besides, the pharmacokinetic parameters such as AUC_(t), C_(max) and untransformed T_(max). The results showed that the differences between two formulations based on the Amaryl were -3.70, -8.28 and 0.61% for AUC_(t), C_(max) and T_(max), respectively. There were no sequence effects between two formulations in these parameters. The 90% confidence intervals using logarithmically transformed data were within the acceptance range of log(0.8) to log(1.25)(e.g., log(0.84)∼log(1.04) and log(0.82)∼log(1.03) for AUC_(t) and C_(max), respectively). Thus, the criteria of the KFDA guideline for the bioequivalence were satisfied, indicating Glimed tablet and Amaryl tablet were bioequivalent.

      • KCI등재

        비유피-4 정(염산프로피베린 20㎎)에 대한 건일염산프로피베린 정의 생물학적동등성

        조혜영,박은자,강현아,백승희,김세미,박찬호,오인준,문재동,이용복 한국약제학회 2004 Journal of Pharmaceutical Investigation Vol.34 No.5

        The purpose of the present study was to evaluate the bioequivalence of two propiverine hydrochloride tablets. BUP-4 (Jeil Pharm. Co., Ltd.) and Kuhnil Propiverine Hydrochloride (Kuhnil Pharm. Co., Ltd.), according to the guidelines of the Korea Food and Drug Administration (KFDA). The propiverine release from the two propiverine hydrochloride formulations in vitro was tested using KP Ⅷ Apparatus Ⅱ method with a variety of dissolution media (pH 1.2, 4.0, 6.8 buffer solutions, water and blend of polysorbate 80 into pH 6.8). Twenty six healthy male subjects, 23.73 ± 2.79 years in age and 67.04 ± 7.93 kg in body weight, were divided into two groups and a randomized 2 x 2 cross-over study was employed. After one tablet containing 20 mg as propiverine hydrochloride was orally administered, blood was taken at predetermined time intervals and the concentrations of propiverine in serum were determined using HPLC method with UV detector. The dis-solution profiles of two formulations were similar at all dissolution media. Besides, the pharmacokinetic parameters such as AUC" C _(max) and T _(max) were calculated and ANOVA test was utilized for the statistical analysis of the parameters using logarithmically transformed AUC, C_(max), and untransformed T_(max). The results showed that the differences between two formulations based on the BUP-4 were 0.17%, 7.98% and 4.55% for AUC,, C_(max), and respectively. There were no sequence effects between two formulations in these parameters. The 90% confidence intervals using logarithmically trans-formed data were within the acceptance range of log(0.8) to log(1.25) (e.g., log(0.88)-log(l .12) and log(0.90)-log(l.15) for AUC, and _(max), respectively). Thus, the criteria of the KFDA bioequivalence guideline were satisfied, indicating Kuhnil Propiverine Hydrochloride tablet was bioequivalent to BUP-4 tablet.

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