외음부의 기저세포암

김보영 ( Bo Young Kim ),황선정 ( Sun Jung Hwang ),박병준 ( Byung Joon Park ),이은실 ( Eun Sil Lee ),한호섭 ( Ho Suap Han ),김용욱 ( Yong Wook Kim ),김태응 ( Tae Eung Kim ),노덕영 ( Duck Yeong Ro ),이안희 ( An Hi Lee ) 대한산부인과학회 2010 Obstetrics & Gynecology Science Vol.53 No.9

Basal cell carcinoma (BCC) is the most common human malignant neoplasm, accounting for 75% of all non-melanoma skin cancer. The incidence of BCC is strongly correlated with sun exposure as well as older age. Therefore, the vast majority of BCCs is observed in elderly patients on the sun-exposed skin of the head and neck with a frequency of more than 80%. BCC is very rare on sun-protected skin such as the perianal and genital regions and other etiologic factors must be considered in these cases. Although the pathogenesis of vulvar BCC is unclear, early diagnosis is very important. Because BCC in these areas sometimes seems innocuous, it is recommended that a biopsy of all suspect lesions be performed. We report a woman with BCC of the vulva treated with wide local resection and reviews the literatures on this subject.

임상 ; 한국 산모와 신생아의 비타민 D 영양 상태 조사

나보미 ( Bo Mi Na ),노소정 ( So Jung No ),김미정 ( Mi Jung Kim ),한헌석 ( Heon Seok Han ),정은환 ( Eun Hwan Jeong ),한영희 ( Young Hee Han ),현태선 ( Tai Sun Hyeun ) 대한주산의학회 2007 Perinatology Vol.18 No.4

목적: 한국 산모와 신생아의 비타민 D 영양 상태를 조사하여 비타민 D 부족의 발생률과 그 정도를 알아보고, 이에 영향을 미치는 요인들을 분석하였다. 방법: 2004년 8월부터 2005년 7월까지 충북대학교병원 산부인과에서 출산한 총 181쌍의 산모와 건강한 만삭아를 대상으로 하였다. 분만시 산모와 제대혈의 혈청 25-OH 비타민 D3(25OHD3), alkaline phosphatase (AP), 칼슘(Ca), 인(P), 부갑상선 호르몬(PTH) 농도를 측정하였으며, 모성 면담과 설문 조사를 통하여 자외선 조사량과 비타민 D의 일일 평균 섭취량을 구하여 비교분석하였다. 결과: 1) 산모와 신생아의 혈청 25OHD3 농도는 각각 23.4±9.9과 16.9±7.5 ng/mL이었다. 2) 8 %의 산모와 22%의 신생아가 비타민 D 결핍 상태였으며, 70%의 산모와 신생아에서 부족 상태를 보였다. 3) 산모와 신생아의 25OHD3 농도는 강한 양의 상관관계를 보였다(r=0.7270, p<0.0001). 4) 산모와 신생아의 비타민 D 영양 상태에 가장 큰 영향을 미치는 요인은 출산 계절로 하절기(6~11월)에 높았다. 5) 다중회귀분석 결과, 산모에서는 출산 계절과 분만 방식이, 신생아에서는 산모의 25OHD3와 분만 방식이 비타민 D 농도와 연관성이 있는 것으로 나타났다. 결론: 한국 산모와 신생아는 비타민 D 영양 결핍이나 부족 상태에 있는 경우가 많았으며, 출산 계절이 비타민 D 영양 상태에 가장 큰 영향을 미치는 것으로 나타났다. Objective: To evaluate the vitamin D nutritional status and its influencing factors in Korean mothers and their newborn infants. Methods: Maternal (n=181) and cord blood (n=180) serum concentrations of vitamin D (25OHD3), calcium, inorganic phosphorus, alkaline phosphatase, intact parathyroid hormone were measured at the time of delivery. We defined vitamin D deficient, insufficient, and sufficient as 25OHD3 <11, 11~30, and >30 ng/mL, respectively. Using questionnaires, average duration of sun-light exposure (minutes/day) and dietary intake of vitamin D (μg/day) were obtained. Results: 1) The mean 25OHD3 level in mothers was 23.4±9.9 (range 4~71.6) ng/mL, and in newborns, 16.9±7.5 (range 0.9~53.6) ng/mL. 2) 8.3% of mothers and 22.2 % of newborns were vitamin D deficient, and 70% of both mothers and newborns were insufficient. 3) Maternal 25OHD3 showed a strong positive correlation with cord blood 25OHD3 (r=0.727, p<0.001). 4) The most significant risk factor for low 25OHD3 levels was the season of birth (June through November) in both mothers and newborns. 5) In multiple logistic regression analysis, the season of birth and the mode of delivery remained significant for maternal vitamin D status, whereas maternal 25OHD3 and the mode of delivery remained significant for neonatal vitamin D status. Conclusion: In conclusion, vitamin D deficiency or insufficiency was relatively common in Korean mothers and their newborn infants, and the most significant risk factor for low vitamin D status was the season of birth.

영아 급성 출혈설 부종 1례

나보미,이진석,하태선,윤태영 충북대학교 의과대학 충북대학교 의학연구소 2004 忠北醫大學術誌 Vol.14 No.1

영아 급성 출혈성 부종 (acute hemorrhagic edema of infancy, AHEI)은 4개월에서 2세 사시의 소아에서 주로 얼굴과 사지에 국한된 염증성 부종과 특징적인 자반성 피부 병변을 보이는 백혈구 파쇄성 혈관염으로, 내부 장기의 침범 없이 급성의 피부 병변을 보이며 대게 1-3주 내에 자연 치유되는 양성질환이다. 이 질환은 비슷한 임상양상이나 조직소견을 보이는 다양한 질환들과의 감별이 필요한데, 특히 소아에서는 Henoch-Schonlein 자반증과의 감별이 특히 중요하다. 이에 저자들은 자반성 피부병변과 얼굴과 사지의 부종 등의 특징적 피부증상과 피부 병리소견을 통하여 AHEI로 진단한 17개월 남아 1례를 경험하였기에 문헌 고찰과 함께 보고하는 바이다. Acute hemorrhagic edema of infancy (AHEI) is a variant of leukocytoclastic vasculitis which is characterized by edema and pupuric skin lesions involving mainly the face and extremities. However, there is usually no visceral involvement. The onset of the disease is acute but self-limited, bearing a benign clinical course within 1 to 3 weeks. The main differential diagnosis of AHEI is Henoch-Schonlein purpura. We report a 17-month old boy with AHEI presenting purpuric skin lesions, edema on face and extremities, and leukocytoclastic vasculitis on skin pathology.

제주에서 플러그묘의 육묘일수가 양배추 생육 및 수량에 미치는 영향

고순보,박용봉,김기택 濟州大學校 亞熱帶農業硏究所 1998 亞熱帶農業硏究 Vol.15 No.-

양배추 플러그 육묘시 적정 육묘일수를 구명하기 위하여 시험을 실시한 결과는 다음과 같다. 1. 플러그묘가 육묘일수에 관계없이 노지육묘묘에 비해 정식시 뿌리의 손상이 적어 활착율이 높았다. 2. 정식초기에는 대묘를 정식한 노지육묘묘의 초장이 길었으나 정식 후 시간이 경과 할수록 플러그묘의 초장이 길어졌다. 3. 2월 수확시 상품수량이 가장 많았으며 25, 30일 플러그묘인 경우 구중은 차이를 보이고 있지 않지만 열구율이 적어 상품 수량이 많았으며 노지 육묘묘에 비해 각각 29.1%, 35.6%의 증수효과를 나타냈다. This experiment was carried out to determine the optimum age of transplant and plugseedlings on plant growth and marketable yields of cabbage in Cheju Island. Plugseedlings raised cabbages taking root rates were compared with outdoor seedling rates after planting. Shortly after planting, the plant height of large outdoor seedlings increased. However, with the passage of time after planting, the plant height of plugseedlings was greater than that of outdoor seedlings. Marketable yields were greatest at February harvest. There was no difference between 25 and 30 days old plugseedlings for head weight and head cracking rates decreased. The yields of 25 and 30 days old plugseedlings increased by 29.1% and 35.6%, respectively, compared to outdoor seedlings.

청소년의 사회인구학적 변인과 체육활동 욕구와의 관계

이보선 龍仁大學校 體育科學硏究所 1998 體育科學硏究論叢 Vol.8 No.1

The purpose of this study is to examine the relationships between background of socio-demography of youth and physical activity of the needs. Data collected through a questionnaire designed for this study consist of fixed-alternative choice response to items constructed to represent the operational definition for each variable. The test items used in measuring sport-related needs in the previous studies were classified, using Cronbach's α analysis. Seven factors and 42 items were selected for the present study. The subjects of the study were 534(M;288, F;246) of youth in Yong-in City. After responses with a low relibility were excluded using a response set method, the data from 534 individuals were analyzed. Analysis of the data was done by analysis of Frequency, t-test, oneway ANOVA, using the statistical package. Based upon the results of the study, the following conclusions appear warranted: First, the background of youth were differentiated by gender. Second, the background of youth were differentiated by education. Third, the background of youth were differentiated by academic career of parents. Fourth, the background of youth were differentiated by income.

복지권으로서 교육권 보장을 위한 『장애인 등에 대한 특수교육법』

황정보,이선재,안병주,강경희,김청아 국립특수교육원 2007 특수교육연구 Vol.14 No.2

결핍에서 오는 필요의 개념은 장애인에게 복지권으로서 교육받을 권리를 가장 잘 말해주고 있다. 장애인은 신체적·인지적 손상으로 발생하는 기본적인 생존적 필요의 충족뿐만 아니라 동시에 교육기회 균등이나 개인차의 고려 등을 통해 무지로부터 벗어날 수 있는 보편적 필요가 충족되어야 함을 논의하였다. 장애인들에게 이러한 결핍에 따른 필요를 충족시켜 줄 이론적 근거가 롤즈(J. Rawls)의 정의론이라 할 수 있다. 정의론의 '차등의 원칙'에 따르면, 교육에 있어 비장애인과 장애인 중 먼저 최소 수혜자인 장애인의 교육복지를 우선하여 극대화할 필요성을 제시함으로써, 그들의 교육권 보장을 위한 이론적 근거에 대한 정당화를 논의하였다. 기존의 특수교육진흥법은 '국가가 교육할 권리'를 가지는 국가 주도적 교육이었다면, 「장애인 등에 대한 특수교육법」 제정은 수년간 장애인의 교육권 확보를 위해 애쓴 장애인 교육 주체들이 노력 끝에 '교육받을 권리'를 찾게 된 의미 있는 결실로 평가되어 진다. The concept of need which comes from lack represents well the right to education as welfare rights to individuals with disabilities. It is necessary to meet the universal need of individuals with disabilities such as an equal opportunity for education and the consideration for individual difference as well as their substantial need. The rationale which may satisfy the need associated with the lack can be J. Rawls's a Theory of Justice. The difference principle by Rawls presents the need of the educational welfare of individuals with disabilities(the least advantaged) to take precedence over that of the non-disabled and be maximized, it is considered that he created the rationale that makes secure their right to education. While established Special Education Promotion Law was national-driven education that state had to the education right, the enactment of 'the Special Education Law for the Individuals with Disabilities, etc.' can be a significant fruit which takes back 'the right to education by citizens' by the educational subjects of the individuals with disability who have taken pains to secure their right to education for years.

코메니우스의 교육과정론

강선보 교육철학회 2002 교육사 교육철학 Vol.27 No.-

The purpose of this study is to examine Comenius's philosophy of curriculum and to seek for the implications for modern education. Comenius insisted at all times that the primary objective of education is the moral and spiritual formation of the individual person. All his ideas were subordinated to this all-embracing principle. Given the radical character of his Christian beliefs-his emphasis on the primacy of conscience and individual responsibility, his pacifism, his advocacy of religious tolerance and ecumenicity, his impassioned commitment to social reform-his ideas in this whole field have a distinctly modern relevance and challenge many of the approaches to ethico-religious education currently advocated by the institutional churches. His application of the methods of his learner-centered pedagogy, and particularly of the doctrine of learning through experience, to the whole sphere of ethico-religious education has a deep relevance to contemporary concerns and provides some challenging, and eminently practical, ideas for the promotion of moral and spiritual education. A pansophic, as distinct from an encyclopaedic, curriculum should give access to what Comenius considered the there main sources of wisdom: knowledge of nature, intellectual knowledge and knowledge of God. There are the essential elements in the philosophy of curriculum. Comenius insists the curriculum must hav esubstantive content: that is, content sufficiently profound to guarantee depth and thoroughness in the pupil's comprehension of all truth. So he emphasizes the need for structural integration in the curriculum. What he insisted most vehemently, however, was that the unity of the curriculum is in essence a moral unity, deriving from the all-informing presence of the spiritual in the sphere of material and finite being. In short, order, unity, depth, range and coherence are the characteristic features of the Comenian curriculum.

벼꽃으로부터 두 개의 calmodulin cDNA 유전자의 분리 및 특성 연구

고보경,고명수,김유정,정일선,최영주 신라대학교 자연과학연구소 2005 自然科學論文集 Vol.14 No.-

Ca^(2+)은 신호전달과정에서 중요한 작용을 하는데 CaM은 이러한 Ca^(2+)이은의 modulator로서 중요한 작용을 하는 것으로 알러져 있다. 벼꽃의 cDNA library로부터 rice genomic DNA(RCaM-2)를 probe로 사용하여 30여개의 Positive clones을 얻어 이 중 두 개의 벼꽃 calmodulin CDNA clone을 분리하였다. RFCaMs CDNA clone의 총염기수는 RFCaM-3은 831p, RFCaM-4는 751bp이고 open reading frame은 각각 149개의 아미노산으로 구성되어 있다. RFCaM-3 과 RFCaM-4의아미노산은 동일하지만 nucleotide 순서는 상당한 차이를 나타내고 있다. RFCaMs CDNA clone의 open reading flame은 protein serine/threonine kinase에 보존되어 있는 catalytic domain을 가지고 있다 RfCaM-3은 5'-untranslated region은 105bp, 3'-untranslated region은 270bp이고 RfCaM-4는 5'-untranslated region은 78bp, 3'-untranslatedregion은 283bp이다. RFCaMs는 Arabidopsis와 70%, potato와는 92%, carrot과는 98%의 유사성을 보였다. Genomic southern blot분석에 의하면 벼의 clamodulin 유전자들이 7-8개의 multigene family로 존재하는 것으로 나타났다. Two different calmodulin (CaM) cDNAs (RFCaM-3 and RFCaM-4) were isolated from a rice flower cDNA library by screening with a rice genomic probe (RCaM-2). Both cDNAs are 90% sequence homologous inside the coding region but are highly divergent outside this region. The polypeptides encoded by RFCaM-3 and RFCaM-4 show identical sequence homology. Comparison of the deduced amino acid sequence of the RFCaMs cDNA clone have identity to Arabidopsis (70%), potato (92%), carrot (98%), and barley and soybean (98%). Southern analysis revealed that both cDNAs are encoded by different genes. Four intense and a few weaker bands were observed in the restriction fragments. Most restriction fragments showed high intensity hybridization signals under stringent conditions, suggesting the presence of a small multigene family for CaM in the rice genome as in other plants.

대학생의 취업스트레스와 자아존중감, 자아효능감, 외모관리행동의 관계

김보라,김유진,김지희,노혜진,오승희,홍지혜,황윤희,박선아 水原大學校 2016 論文集 Vol.30 No.-

Purpose: Many university students are under a lot of job-seeking stress because the employment rate is low. This study sought to determine the relationship between job-seeking stress, self esteem, self efficacy and appearance management behavior amongst university students focusing on nursing. Methods: This descriptive correlational study evaluated the relationships between job-seeking stress, self esteem, self efficacy and appearance management behavior of 340 university students was conducted between September 1 and October 5, 2015. Results: The correlational analysis between job-seeking stress, self esteem, self efficacy and appearance management behavior revealed a negative correlation between job-seeking stress, self esteem and self efficacy and a positive correlation between job-seeking stress and appearance management behavior. In addition, age also correlated with self esteem, self efficacy and appearance management behavior. Conclusion: Stress correlated with self esteem and self efficacy and appearance management behavior. Therefore job-seeking stress may be reduced through not only self esteem and self efficacy enhancement programs but also management according to age.

기계적 합금화에 의한 Al-Fe 및 Al-Fe-Ce 합금의 고온 변형거동

김선진,이도인,안인섭,허보영,조권구 국립경상대학교 공과대학 부설 첨단소재연구소 1992 尖端素材 Vol.2 No.-

The deformation behavior of a mechanical alloyed Al-Fe and Al-Fe-Ce alloy was studied in the temperature range of 300℃ to 500℃. The steady state for Al-8wt.%Fe powder was obtained after 1000 minutes of mechanical alloying at the process condition of 2wt.% stearic acid, 46:1 of grinding media/powder weight ratio, and 300 rpm of impeller revolving velocity. The relative densities of Al-8wt.%Fe alloy powders reached almost 100% after 1 hour sintering at 470℃ under vacuum state. With increasing the amount of PCA, hardness of the sintered alloys increased but the relative densities were not affected. It was also found that decrease in hardness and tensile strength after high temperature aging treatment was reduced with increasing the amount of Ce addition.