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      • 서울의 Penicillinase Producing Neisseria Gonorrhoeae 발생빈도(1996)

        김재홍,황동규,전재홍,김윤석,김중환,김용준,이창균,임동진,김현수,조창근,김경문,박상훈,전우형,김희성,이호정,차명수,김갑형,김형석,김석우,황지환,박병순,권오상,이민수,송기훈,성소영,이인섭,부태성 대한화학요법학회 1999 대한화학요법학회지 Vol.17 No.2

        Background : In recent years, gonorrhea has been panedemic and remains one of the most commom STDs in the world, especially in developing countries. Objective & Methods: For the detection of a more effective therapeutic regimen and assessing the prevalence of PPNG, we have been trying to study the patients who have visited the VD Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results: In 1996, 139 strains of N. gonorrhoeae were isolated, among which 53(39.0%) were PPNG. Conclusion: Our results suggests that after a peak of 74.3% in 1993, the prevalence of PPNG in Seoul is gradually declining.

      • KCI등재

        시간경과에 따른 안정화 이산화염소(Stabilized ClO₂)의 콩팥조직 부패억제에 대한 현미경적 연구

        황규성,최기주,백두진,임도선 韓國電子顯微鏡學會 2008 Applied microscopy Vol.38 No.3

        소취 및 소독제로서 사용되어온 안정화 이산화염소(S-ClO₂)의 조직에 대한 부패억제 효과를 확인하고자 본 연구를 수행하였다. 실험을 위해 8주령 SD계 흰쥐 콩팥(kidney)을 사용하였고, 안정화 이산화염소를 처리하지 않은 대조군과, 안정화 이산화염소의 분말과 수용액을 처리한 실험군으로 구분하여 광학 및 전자현미경으로 관찰하였다. 광학현미경 관찰 결과, 부패양상은 시간경과에 따라 토리, 보우만주머니 및 세뇨관을 구성하는 세포의 핵과 세포사이 경계가 불분명해지며, 세뇨관의 경우 신장되었다가 결국에 수축되었다. 대조군의 1일군부터 괴사(necrosis)가 시작되어 3일군 이후는 전체적인 조직 괴사로 형태를 구별하기 어려웠다. 실험군에서 3일군의 경우, 조직의 전반적 형태와 괴사정도가 대조군의 1일군과 유사하였다. 전자현미경 관찰 결과, 시간경과에 따라 세포소 기관 및 미토콘드리아의 부분적 붕괴로 시작되어 결과적으로 모든 세포내소기관이 붕괴되었다. 대조군의 1일군에서 세포소기관의 부분적 붕괴가 관찰되었으며, 실험군의 3일군에서 세포소기관 및 미토콘드리아의 부분적 붕괴 현상이 관찰되었다. 대조군의 3일군 이후에서는 세포소기관을 구별할 수 없었다. 이상의 연구 결과에서 37˚C, 습도 80±5%에서 안정화 이산화염소(S-ClO₂)가 부패와 변성을 억제하는 부패억제제로서 효과가 있고, 억제 정도는 실험군의 3일군이 대조군의 1일군에 해당하는 것으로 보아 최소 2일 정도의 부패억제 효과가 있는 것으로 확인되었다. The stabilized ClO₂ gas has been used for many years by the food industry as a strong oxidizing and sanitizing agent that has broad and high biocidal effectiveness. Therefore, “stabilized ClO₂” gas may be used in fields of disinfectant and sterilization. But, there have been few studies on the decomposition-inhibition effect of stabilized ClO₂ gas with passage of time. The main purpose of this study was to examine the decomposition-inhibition effect of stabilized ClO₂ gas and the morphological change of kidney by measuring of the light and electron microscope. Sprague-Dawley (SD) rats weighting from 230 gm to 250 gm were used as experimental animals. Under ether anesthesia, the right kidney of rat was obtained. Put each sample in 37˚C and humidity 80±5% incubator, we obtained each sample after 0 day, 1 day, 2 days, 3 days, 4 days and 5 days. We proceeded the observation of light and electron microscope. The results obtained in this study reveal that stabilized ClO₂ gas is an effective decomposition inhibitor until 2 days that was conducted at 37˚C and humidity 80±5% conditions.

      • 간호대학생이 지각하는 임상실습지도자의 교수효율성과 임상실습만족도의 관계

        황현아,김희진,김예지,이규희,이영롱,박성희,손수빈 이화여자대학교 간호과학대학 2012 이화간호학회지 Vol.- No.46

        Purpose: The purpose of this study was to investigate the relationship between teaching effectiveness and clinical practice satisfaction among nursing students. Method: The subjects of this study were 107 junior and senior nursing students in E university. Data were collected using self-reported questionnaire including general and practicum related characteristics, teaching effectiveness of clinical instructors and clinical practice satisfaction from September 12 to September 21, 2011. Collected data were analyzed by SPSS 19 program using t-test, ANOVA with Scheffe test, and Pearson`s correlation coefficients. Result: The mean score of teaching effectiveness was 3.35(±.51), and mean of clinical practice satisfaction was 3.19±.47. There were significant differences of teaching effectiveness of clinical instrutor by satisfaction of overall clinical practicum(F=8.332, p<.001), satisfaction of practice hour(F=3.230, p=.044), and satisfaction of major(F=9.883, p<.001). There were significant differences of clinical practice satisfaction by grade(t=2.274, p=.025), motive of choosing nursing science as a major(F=3.329, p=.007), satisfaction of overall clinical practicum(F=17.437, p<.001), satisfaction of practice hours(F=9.925, p<.001), and satisfaction of nursing major(F=12.748, p<.001). Relationship between teaching effectiveness of clinical instructor and clinical practice satisfaction showed positive correlation(r=.704, p<.001). Conclusion: In this study, teaching effectiveness of clinical instructor was related with clinical practice satisfaction. Therefore, we should consider improving teaching effectiveness of clinical instructor to improve clinical practice satisfaction.

      • 폐도자기로부터 제조된 재활용 소지의 소결특성

        황규홍,한현근,김상우,이종국 조선대학교 생산기술연구소 2007 生産技術硏究 Vol.29 No.1

        As increasing the porcelain as a home ware, the amount of waste porcelain is increased in factory or at home every year. It is very important to recycle the waste porcelain from environmental and economic point if views. Recycling of porcelain body to batch composition can be reduced the manufacturing cost of porcelain by production of raw materials and dropping of sintering temperature about 150~200℃. In this study, we prepared porcelain ceramics by mixing recycled waste ceramic raw materials and normal ceramic raw materials. The waste ceramic raw materials were recycled by crushing and ball milling waste porcelain bodies. The recycled ceramic raw materials after milling have a mean particle size about 22-40 ㎛ with irregular shape and narrow particle size distribution. Shrinkage and sintered density of compacts from recycled ceramic batch composition increased with increasing sintering temperatures, however the sintered density was independent on the amount of the recycled ceramic raw materials. The batch composition containing 30% of recycled ceramic raw materials showed the highest sintered density. Sintered density was decreased over the temperature of 1200℃ due to the creation of cracks on surface and in bulk. It may be concluded that sintering temperature can be reduced in the processing of porcelain body by adding of recycled ceramic raw matehals to normal batch composition.

      • B2B Marketplace의 발전전략

        황상규 진주여자전문대학 2000 論文集 Vol.23 No.-

        The purpose of this paper is to study a developing strategy of B2B Marketplace. Internet and e-commerce is a truly new industrial revolution and the IT industry will eventually be an alternative business model. Especially, B2B Marketplace is working on new business model in cyberspace all of the world. All B2B Marketplaces make a ceaseless effort to adapt themselves to these new circumstances. Also they understand that the change of B2B Marketplace is the competitiveness of company and country. Therefore, we seek to see over recent trends of domestic and foreign B2B Marketplace, to develop new business model of domestic venture companies and to study the developing strategy of them. The results of this paper are as follows. First, it is necessary to a discriminating operation strategy for B2B Marketplace. Because domestic B2B Marketplace is inferior to foreign B2B Marketplace. Second, it is to set up competitive community for B2B Marketplace. Third, it is to develop optimum B2B solution development for B2B Marketplace. Fourth, it is to make efficient contents layout for B2B Marketplace. Fifth, it is to participate the off-line companies to B2B Marketplace for global network reality.

      • 형질전환동물 기법을 이용한 질환동물모델의 활용

        황대연,조정식,김용규,김영상,백상기 충남대학교 생물공학연구소 2002 생물공학연구지 Vol.8 No.1

        Introduction of gene into the germ line of mammals is one of the major recent technology advances in the area of biomedical sciences. Thrasgenic animals have been instrumental in providing new insight into mechanism of gene regulation, and also into the action of oncogenes. Furthermore, the transgenic technology offers exciting possibilities for generating precise animal models for human genetic disease. Transgenic mice expressing each human mutant PS2 gene and APPsw gene under the control of neuron-specific enolase (NSE) promoter, HPV16 E6 oncogene under the control of β-casein gene promoter, and CYP1B1 gene under the control of tetracycline regulator systems were produced in our laboratory. These transgenic mice offer new opportunities to investigate the evaluation and caracteristics of Alzheimer's disease and mammary gland tumor cellular abnormalities and also the effects of toxins, as well as biochemical and cellular mechanism of disease, and, ultimately, will provide systems to test therapeutic strategies.

      • SCOPUSSCIEKCI등재

        사춘기전 Ⅰ,Ⅱ급 부정교합 아동의 기도 면적, 혀의 위치와 안면 형태에 관한 연구

        황용인,이규홍,이기준,김상철,조형준,천세환,박양호 대한치과교정학회 2008 대한치과교정학회지 Vol.38 No.2

        본 연구는 사춘기 성장 이전의 I, II급 부정교합을 갖는 아동 환자들의 측모 두부 규격 방사선사진을 이용하여 두개 안면 형태를 조사하고 이들과 혀의 위치 및 면적, 기도의 면적과의 관계를 조사하여 비인두 기도 및 혀의 형태가 악골 및 부정 교합의 형태에 미치는 영향을 알아보았다. 9 - 11세의 교정환자 76명을 대상으로 측모 두부 규격 방사선사진상 ANB difference를 기준으로 대조군(I급 부정교합군: 0 ≤ ANB difference < 4.0)과 실험군(II급 부정교합군: ANB difference ≥ 4.0)으로 분류하였다. 혀 면적, 혀와 구개 사이의 면적, 비인두 기도 면적과 두개안면형태 항목을 측정하고 비교하여 다음과 같은 결과를 얻었다. 혀 면적, 혀와 구개 사이의 면적, 비인두 기도 면적은 II급 부정교합군과 I급 부정교합군 간에 유의한 차이를 보이지 않았다. Hyperdivergent안면 형태일수록 비인두 기도 면적이 좁았다. 안모의 전후방 수직 길이가 길수록 혀의 면적이 넓었고, 전안면 고경이 길수록 혀는 하방위치 하였다. 비인두기도 면적이 좁을수록 혀의 면적도 좁아졌다. 이상의 연구 결과 혀의 면적과 위치, 비인두 기도의 면적은 I급, II급 부정교합 간에 차이를 보이지 않으며 hyperdivergent 안면 형태 및 안모의 전후방 수직 길이와 관련이 있는 것으로 사료된다. Objective: This study examined the craniofacial morphology of young patients in their prepubertal stage showing class I, II malocclusion, by analyzing lateral cephalograms, and analyzed its relationship with tongue position, tongue space, and airway space in order to ascertain the effects of nasopharyngeal airway and tongue morphology on the form of the malocclusion. Methods: Seventy-six patients aging from 9 to 11 were divided into two groups depending on the ANB difference on the lateral cephalogram: Experimental grouP (CI II malocclusion group) showing 0 ≤ ANB difference < 4.0; Control group (CI I malocclusion group) showing 0 ≤ ANB difference < 4.0. The tongue space, space between palate and tongue, nasopharyngeal airway space and craniofacial morphology were compared between the two groups. Results: Tongue space, Palate-tongue space, nasopharyngeal airway space showed no significant differences between class I and class II malocclusion groups. Hyperdivergent faces were associated with smaller nasopharyngeal airway space. Longer anterior facial height and posterior facial height were associated with larger tongue space, and greater anterior facial height were associated with lower tongue position, Smaller nasopharyngeal airway space showed smaller tongue space. Conclusions: Tongue space and nasopharyngeal airway space showed no significant differences between class I malocclusion group and class II malocclusion group. Only anterior facial height and posterior facial height had an influence on tongue space and nasopharyngeal airway space.

      • 에너지 소비량을 고려한 最適 步行速度 決定

        황규성,김인준,부진후 동의공업대학 1998 論文集 Vol.24 No.1

        Biomechanics as a study of movement and mechanisms of motion with special emphasis on human beings has a long history. It began as early as the time of Aristotle and has since developed as a supplement to various basic sciences such as anatomy, physiology, and mechanics. Since Fenn(1930) presented his first article on running, many arguments have been presented concerning the energetics of human walking and running. Recently, however, Winter(1979, 1980)stated that a variety of analysis techniques and definitions have evolved producing anomalous results and differing conclusions. Then he proposed a definition that not only accounted for any external work but also for the internal work done by the limbs themselves. and presented the results for over-ground level gait. The purposes of the present study were to determine optimum walking speed use of criterion to optimize energy expenditure of metabolism energy and to study the relationship between walking speed and weight.

      • 經濟性 分析을 통한 영업용 택시의 最適交替

        황규성,김상길 동의공업대학 1999 論文集 Vol.25 No.1

        The purpose of this study is to determine the optimum replacement interval for taxis. The optimum replacement analysis calculated annual equivalent cost method for operation and maintain cost add capital recovery cost. So, this study step up the computer in order to select every interest rate quickly and optimally, using computer. This model method in general stage for automobile can be adaptable to every kind of the car enterprises.

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