Serial values for hematologic and biochemical analysis after myocardial infarction in rats

( Mi Jin Lee ),( Hyun Jin Tae ),( Ying Hua Li ),( Do Hyeon Yu ),( In Ae Han ),( Seok Won Lee ),( Dong Choon Ahn ),( In Shik Kim ),( Jin Ho Park ) 한국가축위생학회 2008 韓國家畜衛生學會誌 Vol.31 No.2

To diagnose acute myocardial infarction(MI), many cardiac markers have been used in hematologic and biochemical analysis, and many studies have been published for hema-tologic and biochemical analysis associated with human acute MI. However, after occurrence of acute MI, the serial investigation for values in hematologic and bioche-mical analysis including chronic MI has rarely been performed. To observe the change of the serial values in hematologic and biochemical analysis, we induced artificial MI. The left main descending artery(LMDA) of the left coronary artery was ligated during the progression(day 1, 3, 5, 7, 14 and 30) of MI. Total 66 Sprague-Dawley rats were divided into the sham group(n=24, thoracotomy without LMDA ligation) and the experimental(MI) group(n=42, with LMDA ligation). And all individual in each group was sacrified at day 1, 3, 5, 7, 14 and 30 for the hematologic and biochemical analysis. In comparison of hematologic analysis between the sham and MI groups, the mean values of red blood cell(RBCs), hemoglobin and hematocrit(HCT) showed a steady increase. In biochemical analysis, the mean values of glucose, choles-terol, total creatine kinase(CK) and isoenzyme MB, and lactate dehydrogenase(LDH) were increased in all MI groups compared with the sham groups. The results of this study suggest that early hematologic and biochemical mean values occurred after acute MI are similar to those of human acute MI. In conclusion, we could observe the alterations and serial values in hematologic and biochemical analysis to the extent of chronic status after acute MI.

Serial values for hematologic and biochemical analysis after myocardial infarction in rats

Lee, Mi-Jin,Tae, Hyun-Jin,Li, Ying-Hua,Yu, Do-Hyeon,Han, In-Ae,Lee, Seok-Won,Ahn, Dong-Choon,Kim, In-Shik,Park, Jin-Ho The Korean Society of Veterinary Service 2008 韓國家畜衛生學會誌 Vol.31 No.2

To diagnose acute myocardial infarction (MI), many cardiac markers have been used in hematologic and biochemical analysis, and many studies have been published for hematologic and biochemical analysis associated with human acute MI. However, after occurrence of acute MI, the serial investigation for values in hematologic and biochemical analysis including chronic MI has rarely been performed. To observe the change of the serial values in hematologic and biochemical analysis, we induced artificial MI. The left main descending artery (LMDA) of the left coronary artery was ligated during the progression (day 1, 3, 5, 7, 14 and 30) of MI. Total 66 Sprague-Dawley rats were divided into the sham group (n=24, thoracotomy without LMDA ligation) and the experimental (MI) group (n=42, with LMDA ligation). And all individual in each group was sacrified at day 1, 3, 5, 7, 14 and 30 for the hematologic and biochemical analysis. In comparison of hematologic analysis between the sham and MI groups, the mean values of red blood cell (RBCs), hemoglobin and hematocrit (HCT) showed a steady increase. In biochemical analysis, the mean values of glucose, cholesterol, total creatine kinase (CK) and isoenzyme MB, and lactate dehydrogenase (LDH) were increased in all MI groups compared with the sham groups. The results of this study suggest that early hematologic and biochemical mean values occurred after acute MI are similar to those of human acute MI. In conclusion, we could observe the alterations and serial values in hematologic and biochemical analysis to the extent of chronic status after acute MI.

Histone deacetylase 3 is selectively involved in L3MBTL2-mediated transcriptional repression

Yoo, Jung-Yoon,Choi, Kyung-Chul,Kang, HeeBum,Kim, Young Jun,Lee, Jeongmin,Jun, Woo Jin,Kim, Mi-Jeong,Lee, Yoo-Hyun,Lee, Ok-Hee,Yoon, Ho-Geun Elsevier 2010 FEBS letters Vol.584 No.11

<P><B>Abstract</B></P><P>This is the first report that L(3)mbt-like 2 (L3MBTL2) specifically interacts with the histone deacetylase domain of histone deacetylase 3 (HDAC3) via its MBT domain. Here, we show that L3MBTL2 selectively interacts with HDAC3, but not other class I HDACs. An in vitro peptide-binding assay demonstrated the specific association of HDAC3 with methylated histone-K20 tail and L3MBTL2. Furthermore, depletion of HDAC3 resulted in a decrease of methylated K20-H4, as well as an increase in acetylated histone H3. Consequently, HDAC3 knock-down selectively suppressed L3MBTL2-mediated transcriptional repression. Taken together, our results reveal the concerted action of both HDAC3 and L3MBTL2 in histone deacetylation and methylation-dependent transcriptional repression.</P><P><B>Structured summary</B></P><P>MINT-7719975: <I>L3MBTL2</I> (uniprotkb:Q969R5) and <I>HDAC3</I> (uniprotkb:O15379) <I>colocalize</I> (MI:0403) by <I>fluorescence microscopy</I> (MI:0416)</P><P>MINT-7719941, MINT-7719921: <I>L3MBTL2</I> (uniprotkb:Q969R5) <I>binds</I> (MI:0407) to <I>HDAC3</I> (uniprotkb:O15379) by <I>pull down</I> (MI:0096)</P><P>MINT-7719991: <I>HDAC3</I> (uniprotkb:O15379) <I>physically interacts</I> (MI:0915) with <I>L3MBTL2</I> (uniprotkb:Q969R5) by <I>anti bait coimmunoprecipitation</I> (MI:0006)</P><P>MINT-7719958: <I>L3MBTL2</I> (uniprotkb:Q969R5) <I>physically interacts</I> (MI:0915) with <I>HDAC3</I> (uniprotkb:O15379) by <I>anti tag coimmunoprecipitation</I> (MI:0007)</P><P>MINT-7719897: <I>HDAC3</I> (uniprotkb:O15379) <I>physically interacts</I> (MI:0915) with <I>L3MBTL2</I> (uniprotkb:Q969R5) by <I>two hybrid</I> (MI:0018)</P>

2000학년도 서울교대 신입생 실태조사

이관형,안현미 서울교육대학교 학생생활연구소 2000 學生生活硏究 Vol.26 No.-

2000학년도 서울교육대학교 신입생들의 실태를 조사한 결과, 전체 신입생 525명 가운데 418명의 응답을 토대로 하여 분석하였다. 설문지는 인적 사항, 가정배경, 대학 진학 동기 및 태도, 심리적 특성, 정보화 실태 등의 5영역을 포함하는 충 36문항으로 구성되어 있다. 자료분석은 설문지 각 문항 및 척도에 대하여 남녀별, 학과별 교차분석, 응답내용에 대한 빈도 및 백분율 제시하고 그 결과를 기술하였다. 마지막으로 각 하위 영역별 실태에 따른 주요 특징들을 요약하였다. A Report on the Survery Data for the Actual Conditions of the New Students in the Year of 2000 Kwan-Hyung Lee and Hyun-Mi An We implemented the survey for the actual conditions of the new students in the year of 2000. Among total 525 freshmen in Seoul National University of Education, 418 students replied to the questionnaire for the actual conditions of the new students. Total 36 survey items in 5 survey areas including sociodemographic variables, variables about home background, variables about expected school life, variables about psycologial trait, and variables about information oriented conditions. For each items and scales, we presented frequency and percentage by sex and department and described its meanings. Finally, we summarized results of this survey by 5 survey areas.

임신부의 인플루엔자 백신 접종률 및 관련요인

김미정,이승연,이광수,김아름,손동욱,정문현,박신구,박지현,이병익,이진수 대한감염학회 2009 감염과 화학요법 Vol.41 No.6

Background : During seasonal influenza epidemics and previous pandemics, pregnant women have been at increased risk for complications related to influenza infection. Although influenza vaccination has been widely recommended to pregnant women and immunocompromised hosts, the vaccination rate is presumed to be low in pregnant women. This study was aimed to evaluate the vaccination rate and factors associated with Influenza vaccination among pregnant women, who are at high risk for developing complications from the influenza. Materials and Methods : This study was carried out by telephone survey from April, 2007 to August, 2007. Women who were in their second trimester of pregnancy or above,- during October, 2006 and February, 2007, the recommended vaccination period, and had given birth at Inha University Hospital were selected as the study population. Immunization status, general understanding, and factors associated with vaccination were evaluated. Results : Among a total of 506 eligible pregnant women, 227 (44.8%) responded to the questionnaires. The influenza vaccination rate among the pregnant women was only 4% (9/227). Major reasons for not receiving vaccination were first, not awaring the necessity of immunization during pregnancy (48.5%, 110/227) and second, misunderstanding that it is prohibited during pregnancy (36.1%, 82/227). The major factors that influenced the compliance of vaccination were correct understanding and doctor's recommendation on the influenza immunization during pregnancy. Conclusions : The influenza vaccine coverage on pregnant women was very low and the awareness of influenza vaccination during pregnancy in general was inaccurate. Shift in perception is required and this can be achieved by educating the pregnant women on the safety and efficacy of vaccination. In addition, doctors' active encouragement to vaccination is highly recommended.

노인의 영적 간호요구

최미혜,김경희,김귀옥,김기숙,김수강,김정신,김춘숙,노흥진,박지연,성혜연,오명선,이선희,이원옥,이윤영,이현수,장명재,차혜경,채정선,홍상희 중앙대학교 의과대학 간호학과 간호과학연구소 2001 중앙간호논문집 Vol.5 No.1

This study was designed to exam the aged's needs for spiritual nursing care. The purpose was to serve as a basis for the development of spiritual nursing practice. The major findings are as follows : 1. The degree of needs for spiritual nursing care as area was that needs of love and relationship mean 22.0, needs of meaning and object mean 28.2, needs of forgiving mean 13.5. Total needs for spiritual nursing care mean 63.7, which was on the upper middle level. The needs of meaning and object was rated highest. 2. Among the general characteristics of the subjects, needs of love and relatiohship wasn't significanlty different. 3. Among the general characteristics of the subjects, needs of meaning and object was significantly different according to two factors : age(F=7.260, p=0.001), religion(F=5.275, p=0.001). Higher needs of meaning and object was possessed by the older than the younger, by the one who have religion than the other. 4. Among the general characteristics of the subjects, four factors made a significantly difference to needs of forgiving : sex(t=-2.851, p=0.006), age(F=8.201, p=0.001), religion(F=6.928, p=0.000), disease(t=2.327, p=0.024). Higher needs of forgiving was possessed by man than woman, by the older than the younger, by the one who have religion than the other, by the one who have disease than the other.

한국비서자격시험의 개선점과 비교연구

남자현,이미정,이미영,이아영,정해금,최유정,이미숙,전인선,정혜림 이화여자대학교 법정대학 비서학과 1997 비서학연구 Vol.- No.17

연골외막세포가 포함된 alginate beads를 이용한 토끼에서의 골연골결손 치료

안현정,김은미,정미현,조현철,이인범,성상철,이명철 대한정형외과연구학회 2003 대한정형외과연구학회지 Vol.6 No.2

한성준의 한국 전통춤 사장 : 승무를 중심으로

백현순;이예순;강미선;김현남;이현진 한국무용연구회 2007 한국무용연구 Vol.25 No.1

This paper aims to investigate the origin and movement of Buddhist dance, recognized as the most artistic one of Han sung Jun’s dances and from this draw the idea on Korean traditional dance. First, to summarize the idea on Buddhist dance, on the basis of his biography and historical background of his times, it is believed that the East would look upon the sky as the president of the universe and the origin of life as God; carry out the religious rituals as to natural phenomenon along with human beings. The spiritual thought during the ceremonies is certain to immanent in current Buddhist dance. Buddhist dance is also called “Bǔm-pae”, which means it has a close relationship with Buddhism. And his dance seems to be associated with Buddhism in a degree. The fact, however, that his dance ultimately has not any meaning in it, demonstrates Buddhist dance has the idea of emptiness, that is, “to stay at the quiet state without any mental affliction.” Second, the analysis of his dance shows that the principal motion of Buddhist dance is being represented as Pil-che, Hak-che and Goong-che. In other words, the stirring movement reveals that his dance certainly has a set pattern of points(Pil-che), lines(Hak-che) and circles(Goong-che); It is equivalent to the shape and spirit of the Endless(Mu-kǔk) and the Great Absolute(Tae-kǔk) in the eastern philosophy. Both of them are to result in ǔm-Yang and in this way, the idea of Takǔkǔmyang is obviously indwelling in Buddhist dance. 본 논문은 한국 전통춤의 맥을 이어 온 한성준의 승무를 대상으로 그 춤의 연원(淵源)과 춤사위의 구조(構造)룰 밝혀 춤의 실체인 한국 전통춤을 철학해 보고자 한 것으로 연구 결과는 다음과 같다. 첫째. 한성준 춤의 일대기를 바탕으로 그 시대적 배경에 따른 승우 춤 사상을 정리해 보면 동앙에서는 천(天)·신(神)에게 제사지내는 제천의식을 행해 왔는데 이때 행해지는 천신사상이 오늘날 승무 춤 속에 내재되어 있으며 또한 승무는 불교의식인 범패에서 기원 되어 성행된 것으로 볼 때 승무가 불교사상인 공사상(空思想) 깊은 연관이 있음을 알 수 있다. 둘째, 한성준 승무의 춤사위를 분석해 보면 승무 춤의 대표적인 춤사위가 필체(筆體), 학체(鶴體), 궁체(弓體)로 나타남을 알 수 있으며 이는 동양철학에 있어서 무극(無極)과 태극(太極)구조의 형상과 맥을 같이함을 알 수 있다. 무극과 태국은 곧 음양으로 귀결되며 따라서 승무 춤사위에는 태극음양사상(太極陰陽思想)이 내재되어 있음을 알 수 있다. 한국 전통춤은 익히 알다시피 악(惡), 가(歌), 무(舞)가 함께 어울려 시대의 흐름에 따라 한국인의 정서와 사고를 복합적으로 배태(胚胎)한 것이므로 한국 전통춤을 단순히 하나의 사상만으로 채울 수 없으므로 이상과 같은 결론은 한성준의 승무 춤에 내재되어 있는 한국춤 정신의 극히 일부분일 수 밖에 없다. 그럼에도 불구하고 승무 춤 속에 녹아있는 본질적 사상을 유추해 보고자 한 것은, 한국 전통춤의 대표적언 춤인 승무를 통해, 한국인의 정신인 춤 사상에 함축되어 있는 민족성을 도출해 낼 수 있는 바탕의 자료를 제시코자 한 것이다.

영재 학생들을 위한 과학사-CPS 수업 모형을 활용한 분자생물 영역 수업 프로그램의 개발 및 적용

이주현 ( Ju Hyun Lee ),이미숙 ( Mi Sook Lee ),주희영 ( Hee Young Ju ),이길재 ( Kil Jae Lee3 ) 경북대학교 과학교육연구소 2011 科學敎育硏究誌 Vol.35 No.2

This research was aimed to develop and apply the molecular genetics teaching program based on the history of science and creative problem solving model (HS-CPS model) for gifted students. Based on the strategies of creative problem solving and scientific theory development, the HS-CPS teaching program were developed. This program was applied to 8 first and second graders of the special class for invention activity in a high school. Creative problem solving ability in science and the understanding of DNA and gene concept were tested in pre and post of 12 lessons. The results were as follows: First, creative problem solving ability in science was improved meaningfully. Second, HS-CPS teaching program was effective in the understanding of DNA and gene concepts. Third, the students responded positively to the program evaluation questionnaire.