부동산 가치의 공간자기상관성이 보행친화적인 근린 주거환경과 공동주택 가격과의 관계 분석에 미치는 영향

손동욱 국토연구원 2007 국토연구 Vol.54 No.-

최근 국내외적으로 기존 도시성장 패턴의 폐해를 막고 자연환경을 보존하기 위한 대안으로 스마트성장에 대한 관심이 높아지고 있다. 스마트성장에서는 개발의 고밀화, 토지 이용의 혼합, 오픈스페이스의 보존, 보행 및 대중교통 위주의 도시 환경 조성 등의 원칙을 제시하고 있다. 그러나 이러한 스마트성장의 원칙에 대한 검증은 이론적으로나 경험적으로 아직 충분히 이루어지지 않고 있으며, 특히 미국의 도시계획분야 전문가들 사이에서는 기존의 도시개발 패턴에 익숙한 부동산시장이 스마트성장에서 제시하고 있는 새로운 계획원칙에 의한 도시환경의 변화를 긍정적으로 수용할 수 있을 것인지에 대한 의구심이 제기되고 있다. 시장 선호도 측면에서 특정 요인의 영향을 분석하는 일반적인 기법으로서 가격 데이터를 활용한 헤도닉 모형이 많이 사용되고 있다. 본 논문에서는 미국 워싱턴주의 킹카운티지역 공동주택 가격데이터를 이용한 헤도닉 모형을 측정하여 스마트성장의 계획 원칙들에 의해 형성되는 도시의 물리적 환경요인과 공동주택 가격과의 상관성을 분석하였다. 이는 스마트성장의 계획원칙에 대한 부동산 시장 측면에서의 효과를 검증하기 위한 시도다. 방법론적인 측면에서 본 논문은 헤도닉 기법을 사용할 때 문제의 하나로 지적되고 있는 공간자기상관성으로 인한 통계모델의 불안정성 문제를 해결하기 위한 새로운 공간 샘플링 및 공간분석 기법을 제시하며, 이러한 방법을 통해 실제 공간자기상관성이 헤도닉 가격 모형에 미치는 영향을 분석하였다. 연구결과 일반적인 무작위추출 샘플링 기법을 이용한 샘플 선택방법은 부동산 가격 데이터에 기본적으로 내재된 공간자기상관성을 효과적으로 제거하지 못하여 헤도닉 모형과 같은 선형회귀모델의 통계적 안정성을 상당히 저해하는 결과를 초래함을 확인하였다. 반면에 본 논문에서 제시한 새로운 공간 샘플링 및 공간분석 기법은 공간자기상관성에 효과적으로 대응하여 헤도닉 모델의 안정성을 개선하였다. 또한 본 논문은 공간자기상관성이 헤도닉 모델에 의해 측정되는 각 독립변수의 상관계수와 통계적 유의도를 왜곡시켜 잘못된 결론에 이르게 함을 확인하였다.

In vitro Synergism between Chloroquine and Antibiotics against Orientia tsutsugamushi

손동욱,정문현 대한감염학회 2014 Infection and Chemotherapy Vol.46 No.3

Background: To investigate whether chloroquine enhances the effect of antibiotics against Orientia tsutsugamushi, the causativeorganism of scrub typhus, we compared the effect of antibiotics in combination with chloroquine with the effect of antibioticsalone in vitro. Materials and Methods: The Boryong or AFSC-4 strain was inoculated into ECV304 cells, and incubated in medium containingdoxycycline (4 μg/mL), rifampin (4 μg/mL), azithromycin (0.5 μg/mL), chloroquine (1 μg/mL), and each of these antibiotics incombination with chloroquine for 7 d. Immunofluorescence (IF) staining for O. tsutsugamushi was performed 4 hr and 7 d afterinoculation of the bacteria, and IF-positive foci were enumerated. Results: Chloroquine inhibited the growth of O. tsutsugamushi by 15.5%. In combination with chloroquine, the antimicrobialeffects increased by 4.4% for doxycycline (a 92.9% reduction of bacterial numbers for doxycycline versus a 97.3% reductionfor doxycycline plus chloroquine), 4.6% for rifampin (90.0% versus 94.6%), and 8.3% for azithromycin (86.9% versus 95.2%). The antimicrobial effect of the antibiotics alone was significantly different compared to the combined effect of antibiotics andchloroquine (Wilcoxon signed-rank test, P = 0.001). Conclusions: The combined use of chloroquine with an antibiotic for the treatment of O. tsutsugamushi infections may be usefulfor increasing the efficacy of the antibiotics.

Commentary on “Surgical and Functional Outcomes of Expansive Open-Door Laminoplasty for Patients With Mild Kyphotic Cervical Alignment”

손동욱 대한척추신경외과학회 2021 Neurospine Vol.18 No.4

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민간기업 주도의 도시재생

손동욱 국토연구원 2015 국토 : planning and policy Vol.409 No.-

Test Process 자동화를 위한 Tool 개발에 관한 연구 ( A Study on the Development for the Automation of the Test Process )

손동욱,조영교,이정용,이학수 대한전자공학회 1993 대한전자공학회 학술대회 Vol.1993 No.1

Robotic-assisted gait training applied with guidance force for balance and gait performance in persons with subacute hemiparetic stroke

손동욱,황수진 물리치료재활과학회 2017 Physical therapy rehabilitation science Vol.6 No.3

Objective: Robot assisted gait training is implemented as part of therapy for the recovery of gait patterns in recent clinical fields, and the scope of implications are continuously increasing. However clear therapy protocols of robot assisted gait training are insufficent. The purpose of this study was to investigate the effects of robot-assisted gait training applied with guidance force on balance and gait performance in persons with hemiparetic stroke. Design: Two group pre-test post-test design. Methods: Nineteen persons were diagnosed with hemiparesis following stroke participated in this study. The participants were randomly assigned to the unilateral guidance group or bilateral guidance group to conduct robot-assisted gait training. All participants underwent robot-assisted gait training for twelve sessions (30 min/d, 3 d/wk for 4 weeks). They were assessed with gait parameters (gait velocity, cadence, step length, stance phase, and swing phase) using Optogait. This study also measured the dynamic gait index (DGI), the Berg balance scale (BBS) score, and timed up and go (TUG). Results: After training, BBS scores were was significantly increased in the bilateral training group than in the unilateral guidance group (p<0.05). Spatiotemporal parameters were significantly changed in the bilateral training group (gait speed, swing phase ratio, and stance phase ratio) compared to the unilateral training group (p<0.05). Conclusions: The results of this study suggest that robot-assisted gait training show feasibility in facilitating improvements in balance and gait performance for subacute hemiparetic stroke patients.

장딴지근의 근힘줄 조직특성에 대한 정적 스트레칭과 동적 스트레칭의 효과 비교

손동욱,심재훈 한국신경근육물리치료학회(구 한국신경근육재활학회) 2015 한국신경근육재활학회지 Vol.5 No.1

The objective of this study is to determine the effects of static and dynamic stretching exercises on the gastrocnemius muscle-tendon properties by use of ultrasonography. Twenty healthy adults participated in the present study. The subjects were asked to engage in static and dynamic stretching exercises of the gastrocnemius for 30 sec each in 2 sets. Ultrasonography to measure the displacement of the myotendinous junction (MTJ) was performed at the 0 sec, 30 sec, 60 sec, 180 sec, and 300 sec after the stretching exercises. A significant displacement of the static stretching was observed between the 0 sec and 30 sec, and between the 180 sec and 300 sec (p<0.05), with no significant changes between the 30 sec and 180 sec. And dynamic stretching exercise showed more significant displacement in the all conditions compared with static stretching (p<0.05). The displacement of the MTJ position was observed in proximal parts, and dynamic stretching appeared to make the change in distal parts. Therefore, static and dynamic stretching exercises of the gastrocnemius showed different change rate and position displacement direction.

원발성 간 MALT 임파종

손동욱,최윤아,김철현,김희구,최새로운,박현주,이돈행,김형길,김영수,신용운 대한내과학회 2008 대한내과학회 추계학술대회 Vol.2008 No.-

혀혈성 뇌혈관질환에서의 두개강외-두개강내 우회로 조성술

손동욱,이상원,최창화 부산대학교 병원 암연구소 2007 부산대병원학술지 Vol.- No.21

OBJECTIVE: To examine the potential role of cerebral revascularization in the treatment of patients with symptomatic occlusive cerebrovascular disease refractory to medical therapy, we prospectively reviewed 12 patients who underwent extracranial- intracranial (EC/IC) bypass surgery. METHODS: A series of 12 patients treated in a 3-year period met the following criteria, 1) symptomatic internal carotid artery(ICA) or middle cerebral artery (MCA) obstruction or stenosis over 80%,2) decrease in basal cerebral blood flow (CBF) over 10%,3) hyporeactivie CBF to acetazolimide. Among them, the type of ischemic episode was transient ischemic attack (TIA) in seven, minor stroke in four , and major stroke in one. Of these, nine patients had multiple episode of ischemic attack. CT or MRI showed infarction of the MCA territory in two , border zone infarction in three, basal ganglia infarction in two and multiple lacunar infarction in five. Angiographic findings included internal carotid artery occlusion in ten patients and middle cerebral artery occlusion in two. Based on our criteria, superficial temporal artery (STA)-MCA anastomosis was performed in 12 cases. RESULTS: Average follow up period was 21.58 months. Postoperative course was uneventful in ten patients. One patient suffered a postoperative stroke (hyperperfusion syndrome) with complete recovery and another suffered an operative wound infection. Of the 12 patients, 11 (91.6%) have had an excellent to good outcome with complete resolution or significant improvement of preoperative neurologic symptom, while remaining one showed no improvement. Bypass patency was confirmed by postoperative angiography in all cases. Postoperative follow up studies of the basal CBF and response of the CBF to the acetazolamide showed significant increased CBF activity to acetazolamide in 11 cases (91.6%) while the basal CBF was essentially unchanged in all cases except for two. CONCLUSION: Although the Cooperative Study on Extracranial-Intracranial Bypass failed to show a benefit from the bypass procedure, carefully selected individuals with occlusive cerebrovascular disease and persistent ischemic symptoms, despite maximal medical therapy, seem to obtain remarkable benefit from cerebral revascularization. Our results suggest that EC-IC bypass surgery should be considered in patients with hemodynamic cerebral ischemia in order tp improve the cerebrovascular reserve capacity.

포스터 전시 발표 : 소화기 ; 원발성 간 MALT 임파종 1례 (초)

손동욱,최윤아,김철현,김희구,최새로운,박현주,이돈행,김형길,김영수,신용운 대한내과학회 2008 대한내과학회지 Vol.75 No.1S