젊은 남자 성인의 칼슘과 철의 영양상태에 관한 연구

박영숙,곽주영,권지혜,류화라 순천향대학교 기초과학연구소 2002 순천향자연과학연구 논문집 Vol.8 No.1

A survey was performed to 174 male young men who were living alone(40 persons) and shared living with friends(4143 persons) in Chungnam province. Their average age was 22.6 years old, height 171.8 ㎝, and weight 65.6 ㎏. Their daily calcium intake level was averaged 271.9±169.1 ㎎, which was 38.8 %RDA. Comparing calcium intake of each mealtime, breakfast, lunch, dinner, and snacks were composed of 18.6%, 30.0%, 34.0% and 17.4%, respectively. Their daily iron intake level was averaged 8.9±10.8 ㎎, which was 74.3 %RDA. Comparing iron intake of each mealtime, breakfast, lunch, dinner, and snacks were composed of 15.4%, 33.6%, 36.3% and 14.7%, respectively. These results suggested that deficiency of the two minerals in young male adults were severe and the nutrient qualities were also poor, no matter of their living alone or with accompanies. The deficiency was more profound in calcium than iron. And we observed iron nutriture differed significantly according to their living status, such as iron intake and its %RDA were significantly worse in single living subjects than the others. However calcium did not show significant difference. We concluded that shared living environment in young male adults could possibly improve their dietary mineral intake levels.

Helicobacter pylori와 대장균의 Shuttle Vector 개발

조명제,이우곤,이상룡,김경희,안영숙,김성희,김현주,류복덕,최여정,윤영혜,백승철,전영석,이광호 경상대학교 유전공학연구소 1997 遺傳工學硏究所報 Vol.16 No.-

In this study, a vehicle vector using cryptic plasmids was constructed for gene transfer in Helicobacter pylori. pHP51(3.9 kb) and pHP489(1.2 kb) were selected for constructing vectors from cryptic plasmid of H. pylori isolates in Korea. The HindⅢ-digestedDNA fragment(1.2kb) of pHP489 and 1.6kb DNA fragment of pHP51 were ligated with a kanamycin resistance gene(aph3'-Ⅲ) from C. jejuni to produce the recombinant plasmids pHP489K and pHP51K, respectively. Transformation frequency of pHP51K by electroporation was low. But pHP489K could be effectively transformed into various H. pylori strains. In order to design an intermdiate vehicle vector for gene transfer into H. pylori, pBlueHP489K was prepared by recloning pHP489K DNA into pBluescript and pTZ19R vector. This vector permitted the DNA fragment containing pHP489 sequence, aph3'-Ⅲ, and cloned DNA to be cut and self-ligated in the SacⅠ site after cloning. ureA and ureB gene were inserted into pBlueHP489K, resulting in pBlueHP489K/AB. The DNA fragment containing pHP489, kanamycin resistance gene(aph3'-Ⅲ), and urease structural gene was cut away from pBlueHP489K/AB and self-ligated to generate pBlueHP489K/AB. pBlueHP489K/AB made urease-negative H. pylori strains restore their urease activity. By this experiment, pBlueHP489K was confirmed to be the vehicle system for transferring H. pylori genes.

서산지역 굴피나무(Platycarya strobilacea)군락의 동태

류영수,허혜경,김성덕,박경배 忠南大學校 環境問題硏究所 1997 環境硏究 Vol.15 No.-

The regeneration process and the composition of species of climax Platycarya strovilacea S. et Z. forest was studied in Mujang-Ri, Jigok-Myon, Sosan, Chungchungnam-Do Province. Total number of vascular plant species of this community was recorded 125. This results seem to be related to various soil and light conditions in this community. The dominant trees of the stands came up beyond 12m in height. The upper tree layer is highly dominated by Platycarya strovilacea, which have more than two stems, is over 15cm in DBH class and is like stumps. They were distributed horizontally in random. Trees of the middle and lower layer were few in number and small in basal area. It tended to be distributed contagiously, in the age distribution of trees, some of the even-aged cluster which were constituted of several trees, were found in plot. The growth rates of the stem diameter for the first 20 years of the trees in upper layer were higher than those of the same species in the middle layer. These results show that the seedings which were established in dense grows with the decreasing density after the forest canopy had been broken out , and distribution pattern became in random, would constitute the canopy developing the community level.

保精湯의 抗癌 및 免疫增强效果에 關한 硏究

류기원,박동원,류봉하,김혜영 경희대학교 1998 慶熙醫學 Vol.14 No.3-4

만성신부전 환자에서 발생한 파종결핵

정가영,나선경,윤혜원,송하응,류정화,류동열 이화여자대학교 의과학연구소 2013 EMJ (Ewha medical journal) Vol.36 No.1

Patients with chronic renal failure (CRF) are known to be more susceptible to tuberculosis infection due to impairment of the host defense mechanism. Although extrapulmonary tuberculosis is more prevalent in those subjects and it may induce dismal outcome, its diagnosis has been challenging since there is no specific symptoms of the disease and the clinical course is usually atypical. Herein, We report a case of disseminated tuberculosis diagnosed by ultrasound-guided liver biopsy in a 31-year-old CRF patient presenting sustained fever despite broad-spectrum antimicrobial therapy and progressive cholestatic jaundice.

참외 흰가루병에 대한 살균제의 예방 및 치료효과 검정

장태현,류연주,임혜정,임수진,최미영,정병룡,김철웅,이용세 한국환경농학회 2006 한국환경농학회지 Vol.25 No.1

방사선 치료를 받는 암 환자들의 사회적 지지와 삶의 질과의 관계

정주희,류소연,윤혜은,남택근,오윤경,안현옥,박계남,이영선 朝鮮大學校 附設 醫學硏究所 2002 The Medical Journal of Chosun University Vol.27 No.2

Objective : This study was performed to investigate the relationship between social support and quality of life among cancer patients receiving radiation therapy. Matehals and Methods : The data were collected from 98 patients, who were receiving radiation therapy at two university hospitals located in GwangUJu, used by structured questionnaire. For statistical analyses of the association between quality of life and various characteristics, data were analyzed using t-test, ANOVA, Pearson 's correlation, and multiple regression analysis. Results: 1. There were 56(57.1%) males and 42(42.9%) females. Age ranged from 21 to 82 years. The primary sites of cancer were gastrointestinal tract (24.5%), lung (23.5%), breast (21.4%), and head and neck (11.2%) in order. 2. The mean scores of social, family, and medical support were 4.30 0.58, 4.49 0.78, 4.11 0.65, respectively. The score of quality of life was 5.83 1.63 (range: 1.95 ~ 9.05). 3. An analysis of the association between several factors of patients and quality of life showed that the statistically significant factors were age, the presence of distant metastasis, family support, medical support and social support. 4. As a result of the multiple regression analysis, only social support was significant (β=0.932, P=0.02) with quality of life, but age and presence of distant metastasis were not significant. Conclusion : This suggests that quality of life in cancer patients could be improved by strengthening the social support which consists of family and medical support. Further study would be necessary to evaluate separately several aspects of quality of life among cancer patients.

농장 사육되는 타조에서 나타난 다리 기형의 증례 보고

최종윤,손화영,전무형,조성환,김혜성,류시윤,박배근,이영원,윤원기 충남대학교 수의과대학 동물의과학연구소 2001 動物醫科學硏究誌 Vol.9 No.-

Two farmed young ostrich chicks were applied to pathology laboratory at Chungnam National University. Grossly, one ostrich showed rotated tibiotarsus, the other showed rolled toes. Case 1 ostrich was hypertrophy of fibualis longus and tibial cranialis tendon and gastrocnemius tendon in crus, inflammation of flexor digitorum longus. In histopathological views, myocytes of fiburalis longus were showed hypertrophy and hyperplasia. It is not found any specific feature in X-ray of the case 2 ostrich. Limb deformities were detected frequently in farmed ostrich chicks in 2- to 3 weeks old. Limb deformities were an important cause of mortality in farmed ostrich chicks during the first 10weeks after hatch. Cause of limb deformities were considered a nutrition problem.

세계 정상급 멀리뛰기 선수들의 도움닫기, 발구름 동작과 에너지 변환에 관한 연구

류재균 ( Jae Kyun Ryu1 ),송주호 ( Joo Ho Song ),장재관 ( Jae Kwan Chang ),김혜영 ( Hye Young Kim ) 한국스포츠정책과학원(구 한국스포츠개발원) 2012 체육과학연구 Vol.23 No.4

이 연구는 도움닫기 마지막 세 스트라이드 및 발구름 동작에서 일어나는 동작 변화를 세 개의 운동면에서 분석하고 발구름 구간에서의 에너지 흐름의 특성을 분석하는 것이다. 이 연구는 2011년 대구세계육상선수권대회에서 남자 멀리뛰기 결승에 진출한 선수들 중 1위에서 8위에 입상한 선수들을 대상으로 5대의 Sony 비디오 카메라를 사용하여 60Hz로 선수들의 운동장면을 촬영하였으며 Kwon3d 프로그램을 이용하여 운동학적 자료를 산출하였다. 또한 에너지 흐름의 특성을 분석하기 위하여 에너지 변환지수와 에너지 전환효율을 계산하였다. 분석 결과 다음과 같은 결론을 얻었다. 도움닫기 마지막 세 스트라이드의 보폭 변화는 전형적인 멀리뛰기 보폭 변화인 보통-길고-짧게 하는 보폭 패턴을 보였으며, 스트라이드 각은 페널티메이트에서 모든 선수들의 스트라이드 각이 크게 나타났다. 수평면에 투영한 도약각도는 이륙순간 좌우속도에 따라 구름판 이륙시점에서 우측 혹은 좌측으로 도약각이 결정되는 것으로 나타났다. 전후면에서 접지순간 다리의 각도가 작을 경우에는 구름판에서 수평속도의 제동이 되는 것으로 나타났다. 이륙순간 다리의 각도가 작게 되면 도약각도는 클 수 있으나 구름판에서 발구름 동작으로 인한 수평속도의 추진력이 떨어지는 것으로 나타났다. 좌우면에서 이륙순간 다리의 각도는 접지에서 이륙순간으로 진행되면서 발구름 다리의 각도가 서로 교차되는 것으로 나타났다. 에너지 변환지수는 경기력이 우수한 선수일수록 높게 나타났으나 Watt 선수처럼 도약각이나 구름판 이륙순간 수평속도의 감속이 크면 작게 나타났다. 에너지 전환효율은 선수들간에 큰 차이를 보이지 않았지만 구름판 이륙순간에서 수평속도의 감속이 크고 수직속도가 크게 증가되면 높게 나타났다. The purpose of this study is to reseach the kinematic variables of the last three strides on the cardinal planes and the energetic processes of take-off performance. The subject of this research were the athletes whos ranked within top eighth of the long jump competition at the 2011 Teagu world championship. Each long jump was recorded using a video camera operating at 60Hz and Kwon3D program was used to analyse the video images of the jumps and the results were as follow: 1. The stride patterns of the subjects utilized the long penultimate-short last stride strategy except Manyongga. All subject of 2nd stride angles showed higher angels. 2. The take-off angle in the horizontal plane was determined with medio-lateral velocity. If the angel of leg placement in the sagittalple was smaller the horizontal velocity decreased a lot. The angle of leg placement in the frontal plane was twiseted at the take-off phase. 3. The transformation index values were higher with the whos performed superior but lower with subject like Watt whos performed on the higher take-off angle and the higher decreased horizontal velocity at the take-off board. 4. The conversion efficiencies were not showed any differences among the subjects but were showed higher with the higher decreased horizontal velocity and increased vertical at the take-off board.

반코마이신 내성 장내구균 분리 환자에서 황색포도알균의 내성

김동욱,신선혜,김혜진,류선,이선희,장철훈,김영대,곽임수 대한감염학회 2004 감염과 화학요법 Vol.36 No.1

목적 : Vancomycin-resistant enterococci (VRE)로부터 S. aureus로의 vacomycin 내성 유전자의 전파는 오래전부터 예견되어져 왔으며 큰 걱정거리로 남아있다. 최근에 vanA 유전자를 가지고 있는 vancomycin-resistant S. aureus 2주가 미국에서 분리되었다. 이 연구의 목적은 VRE를 보균하고 있는 환자들에서 S. aureus 보균양상과 항균제 내성을 알아보는데 그 목적이 있다. 재료 및 방법 : 2001년 1월부터 2001년 12월까지 부산대학교병원에 입원하였던 환자들 중 임상검체에서 VRE가 분리된 환자 7명과 2001년 9월부터 12월까지 외과 중 환자실에 입원하였던 환자들 중 VRE 감시배양을 시행하였던 20명의 환자들을 대상으로 하였다. 환자들은 전비공, 액와부, 회음부, 직장에서 매주 면봉으로 검체를 채취하였다. 선별배지에서 검체를 배양하여 S. aureus를 분리하였고 원판 확산법을 이용하여 methicillin 감수성을 측정하였다. Broth microdilution 법으로 vancomycin MIC를 측정하였다. 결과 : 총 27명에서 73회의 방문과 292회의 배양이 시행되었으며 총 67주의 S. aureus가 분리되었다. 이중 64주(95.5%)가 methicillin 내성이었다. 전비공 MRSA 보균율은 VRE를 보균하고 있었던 환자는 19명 중 11명(58%)에서, VRE를 보균하지 않았던 환자는 8명 중 3명(37.5%)으로 VRE 보균자에서 보균율이 더 높았다. 총 64주의 MRSA의 vancomycin MIC의 분포는 0.5-2㎍/mL였으며 2㎍/mL를 초과하는 균주는 발견되지 않았다. 64주 중 vancomycin MIC가 1㎍/mL인 균주가 54주(84.4%)로 가장 많았으며 2㎍/mL 6주(9.4%), 0.5㎍/mL 4주(6.3%)의 순이었다. 결론 : VRE 환자에서 S. aureus의 보균율은 비보균자 보다 높았으며 분리된 균주들은 대부분 MRSA였다. VRSA 균주는 발견되지 않았다. Background : The transfer of vancomycin resistance from vancomycin-resistant enterococci (VRE) to Staphylococcus aureus has been predicted. The purpose of this study is to determine the prevalence and antibiotics resistance of S. aureus among patients colonized with VRE. Methods : Between January 2001 and December 2001, a prospective study was performed at Pusan National University Hospital on 27 patients. Surveillance swabs from nasal cavity, axilla, perineum, and rectum were obtained at weekly intervals. Methicillin susceptability of S. aureus was determined by oxacillin disk diffusion test and minimum inhibitory concentration (MIC) for vancomycin by microdilution broth test. Results : Total of 292 swab cultures were performed and 67 S. aureus isolates were collected. 64 isolates (95.5%) were resistant to methicillin. The prevalence of nasal MRSA carrier in 19 patients colonized with VRE was higher than that in 8 patients not colonized with VRE (58% vs. 37.5%). In 64 MRSA isolates, MIC (㎍/mL) for vancomycin ranged from 0.5 to 2. No isolates with MIC >2 ㎍/mL were observed. MIC of 1 ㎍/mL was shown (observed) in 54 isolates, 2 ㎍/mL in 6 isolates, and 0.5 ㎍/mL in 4 isolates. Conclusion : The prevalence of S. aureus with colonization of VRE is higher than that without colonization of VRE. Most of S. aureus isolates were resistant to methicillin. VRSA isolates were not observed.