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      • 가상환경을 위한 효율적인 3차원 협동 저작 기법

        최명아,차지은,유지현,엄성용 서울여자대학교 컴퓨터과학연구소 2003 정보기술논문지 Vol.1 No.-

        In this paper, we propose a new 3-dimensional cooperative authoring tool the environments. In this method, we clearly define the roles of authors Involved In the cooperation and extend the functionality of the each client system, and thus reducing the overload in server systems and/or the network bottleneck than existing client-server models, while minimizing the locking delays of the existing pessimistic locking mechanism. In addition, we use scene-graphs of Java 3D to represent the rapidly changing scenes vividly 본 논문에서는 새로운 3차원 협동 저작 기법에 대해 설명한다. 이 방법에서는 협동 저작에 참여하는 작업자에 대한 명확한 역할 구분과 클라이언트의 기능 확장을 통해, 기존의 클라이언트-서버 구조가 갖는 서버 부담 및 네트워킹 병목 현상을 완화하는 한편, 기존의 '비관적 잠금 기법'에서 발생하는 작업 공유에 따른 불필요한 대기 시간을 줄인다. 또한 자바 3D의 '장면 그래프'를 이용하여 장면을 표현함으로써 실시간 장면 정보의 변화를 빠르고 쉽게 반영하였다.

      • KCI등재후보

        정신분열병의 선택적 주의력 저하의 보상 기전

        최지욱,정범석,김지웅,김성윤,권준수,전덕인,김창윤 大韓神經精神醫學會 2004 신경정신의학 Vol.43 No.6

        Objectives : This study investigated the compensatory neural correlate of selective attention deficit in schizophrenics Show-ing near-normal performance. Methods : A 'modified Stroop' was developed that can be used measure the response time during functional imaging. An event-related functional magnetic resonance imaging study was carried out in 10 clinically stabilized schizophrenics and 10 healthy controls during the performance of a 'modified Stroop'. In the 'modified Stroop', the subjects were required to respond with a two-button mouse to whether or not the color of a subsequent word corresponded to one of T-shirt. The significantly activated brain regions were investigated in a voxel-wise Mest of the Stroop load. Results : Schizophrenics, compared with healthy controls, showed poorer response time, but had similar accuracy. Compen-satory activation in the right inferior frontal gyms (IFG) was observed in schizophrenics. The left paracingulate sulcus was less activated in the schizophrenics than in the healthy controls. Conclusion : These results suggest that, in schizophrenics showing a normal accuracy during the Stroop, selective attention deficits might be related to the left paracingulate sulcus as well as the anterior cingulate. In addition, their deficits may be compensated with the right IFG.

      • 개의 아토피 피부염에 대한 Leflunomide의 임상적 적용 1례

        홍은지,윤기영,서경원,최호정,정성목,송근호,조종기,박성준 忠南大學校 獸醫科大學 附設 動物醫科學硏究所 2012 動物醫科學硏究誌 Vol.19 No.1

        A Shih-tzu(8-year-old, castrated male) was referred to the Veterinary Medical Teaching Hospital of Chungnam National University with the history of relapsing pruritus, recurrent dermatitis. On the physical examination, generalized erythema, otitis externa, alopecia and lichenification were observed. Using Favrot's criteria for diagnishing atopic dermatitis, 7 criteria were satisfied out of 8 criteria. After treatment for infection, intradermal skin test was performed(positive allergen : Df, Dp). And then immunotherapy was performed, but clinical signs were not getting better. Next treatment of glucocorticoid shown little improvement of clinical signs, and adverse effect(diarrhea) was shown after cyclosporine application. So application of leflunomide which is used for human atopic dermatitis treatment in some case was planned. After 6 months of application of leflunomide, clinical signs were decreased gradually.

      • KCI등재

        Evaluation of the Depth of Deteriorations in Concrete Bridge Decks with Asphalt Overlays Using Air-Coupled GPR

        Ji-Young Rhee,Jae-Jin Choi2,Seong-Hoon Kee 한국콘크리트학회 2019 International Journal of Concrete Structures and M Vol.13 No.3

        In this recent work, a ground penetrating radar (GPR) technique was proposed to evaluate the deteriorated depth of concrete bridge decks with asphalt overlays in the Korea expressway network. Air-coupled GPR was utilized in the measurement of the relative permittivity of concrete on bridge decks with asphalt overlays and the electromagnetic (EM) wave attenuation of the concrete cover of top reinforcing bars (rebars) in the pilot bridge in public service. In addition, 13 core samples were obtained from the bridge deck to carry out a detailed survey that includes visual inspection of the deterioration and measurement of chloride content with depth. The validity of the GPR technique was examined by comparing it with the results of the field investigation. Moreover, the correlation of the deteriorated depth with either the relative permittivity or EM wave attenuation was established. Results show that a GPR signal analysis method based on a dual-criteria (relative permittivity and EM wave attenuation) is more effective in analyzing the deterioration characteristics and evaluating the deteriorated depth of concrete bridge decks with asphalt overlay compared to the analysis method based on one of the two GPR properties. Results of the field test are considered to be significant wherein it establishes a relationship between the GPR property and deterioration characteristics of the bridge decks. Moreover, results show the practical applicability of the GPR technique in evaluating the deteriorated depth of the bridge decks with asphalt overlay.

      • KCI등재

        우리 나라 패션 산업을 위한 패션 비지니스 리엔지니어링에 관한 연구

        최은정,韓誠智,洪仁淑,金文淑 服飾文化學會 1999 服飾文化硏究 Vol.7 No.4

        The purpose of this study is to remind the necessity of reengineering establishment of future-oriented fashion industry and to research the sevices for the system establishment at this present time when the consumer's demands level is extremely high. This research has been done by the literature review of the relative articles, books and the case study. First, through the analysis of the important changes and movements of fashion industry environment by the environmental interpretation model of Draft and Weick, the strategic development, corresponding the environment change of fashion indudtry, has been attempted. Second, this study examined QR integration management method according to the Kunz's behavior theory of the apparel firms. Third, as the prior occupation strategy regarding the things can be done very well from now on the things are needed, the necessity and establisnment of SCM, based on companionship and beyond the boundary between the companies has been studied through the exchange of the data of manufacture and sales which has been regarded as the secret of the companies. Finally, to become a company to lead the market, in addition to the re-organization of the internal process of a company with the leadership which has the clear vision for the consumer's satisfaction, the process have to be integrated under the cooperation with its business partners and the cost have to be reduces, and the time which takes to correspond to the consumer's requirements have to be reduced.

      • KCI등재

        Lesch-Nyhan 증후군 환아의 자해에 의한 혀의 외상

        김지희,최병재,김성오,최형준,손흥규,이제호 大韓小兒齒科學會 2008 大韓小兒齒科學會誌 Vol.35 No.3

        Lesch-Nyhan 증후군은 드물게 나타나는 X 염색체 열성 유전 질환으로 purine의 대사 장애를 보이는 질환이다. Purine의 대사 장애는 대사에 관여하는 효소인 hypoxanthine guanine phosphoribosyl transferase의 결손 또는 활성 감소로 인하여 나타나며,요산의 과다 생산에 의한 요산과다혈증,요산과다뇨증 등의 신장계 증상과 정신지체,무도증 등의 신경학적 장애를 보이고,구강이나 손가락에 대한 자해를 나타낸다. 이 중 자해 행위는 입술과 혀,손가락을 깨무는 경우가 흔하고,심하면 혀와 손가락이 완전히 절단될 수도 있다. 이 경우 자해로 인한 통증뿐 아니라,연조직 결손으로 인한 심미적인 문제와 상처 부위로의 2차 감염이 발생할 수 있다. 이러한 Lesch-Nyhan 증후군 환자에서 자해를 막기 위해 여러 방법이 사용되고 있는데,이 중 치과적으로 접근하는 방법으로는 마우스 가드나 lip bumper 등의 장치를 이용하는 방법과 해당 치아들을 모두 발거하는 방법,악교정 수술을 통해 개방 교합을 형성해 주는 방법 등이 있다. 본 증례는 13세 9개월의 Lesch-Nyhan 증후군 환아로서 자해에 의해 혀에 심각한 외상을 가한 경우로 마우스 가드를 이용한 보존적인 방법을 사용하였으나 계속적으로 혀에 외상을 가해 하악 전치 뿐 아니라 구치까지 발거하여 치료하였다. Lesch-Nyhan syndrome is a rare X-linked recessively inherited disorder, caused by complete absence or decrease in activity of hypoxanthine guanine phosphoribosyl transferase(HPRT), an enzyme involved in purine metabolism. This enzyme deficiency gives rise to nephropathy symptoms, such as hyperuricosuria and hyperuricemia by excessive uric acid production and neuropathy symptoms, such as mental retardation, choreoathetosis and self mutilation behavior. Patients with Lesch-Nyhan syndrome have tendency to bite their liP, tongue and finger, In severe cases, partial or even total amputation of tongue or finger occur. Self-inflicted bites are often complicated by secondary infection to the injured site as well as pain. Furthermore tissue loss by biting results in esthetic problems. The dental management of self mutilation includes treatment with appliances such as soft mouth guard or lip bumper, extraction of all the teeth, and orthognathic surgery. We report a case of a 13 year-old boy with Lesch-Nyhan syndrome, who severely injured himself on his tongue. At first, conservative treatment using soft mouth guard was considered, but it could not prevent trauma on his tongue. Therefore, extraction of the lower anterior and posterior teeth was carried out.

      • KCI등재

        사회적 상호작용을 강조한 과학 탐구실험의 효과

        김지영,성숙경,박종윤,최병순 한국과학교육학회 2002 한국과학교육학회지 Vol.22 No.4

        사회적 상호작용을 강조한 과학탐구실험이 학생들의 학업성취와 과학탐구능력 및 학습동기에 미치는 효과에 대해 연구하였으며, 탐구실험 수업이 소집단의 구성방식에 따라 어떠한 차이를 나타내는지 알아보기 위해 인지수준이 동질인 집단과 이질인 집단의 효과를 비교하였다. 이를 위해 중학교 2학년 255명을 통제집단과 실험집단으로 나누어, 실험집단에는 사회적 상호작용을 강조한 과학탐구실험 수업을, 통제집단에는 전통적인 실험 수업을 1년간 적용한 후 과학학업성취도, 과학탐구능력, 학습동기 검사를 실시하였다. 사회적 상호작용을 강조한 탐구실험은 이끌어내기, 친숙해지기, 구성하기, 확장하기의 4단계로 구성되어 있으며, 관찰 현상을 학습과 연관시키고 실험을 설계하며 결론을 이끌어내는 과정을 통해 동료 및 교사와 상호작용을 할 수 있도록 구성되어 있다. 연구 결과 사회적 상호작용을 강조한 과학탐구실험은 학생들의 학업성취와 과학탐구능력 및 학습동기에서 유의미한 효과가 있었다. 모든 인지수준의 학생들에게 효과가 나타난 것은 아니었으나 대분분의 인지 수준에서 학업성취의 효과가 크게 나타났으며, 학업성취에 비해 과학탐구능력의 향상정도가 낮았다. 소집단 구성에 따른 효과에서는 동질집단이 이질집단에 비해 성취도와 학습동기에서 유의미한 향상이 있었다. 이러한 결과는 과학탐구실험에서 상호작용이 중요하며, 상호작용이 학생들의 성취도와 탐구능력 향상에 긍정적 영향이 있음을 시사한다. This study investigated the effects of scientific inquiry experiments emphasizing social interaction on the academic achievement, the ability for science inquiry and the learning motivation of the students. To examine the differences among the classes of scientific inquiry experiments according to the way of organizing small groups, the effects of the group in homogeneous cognitive level and the group in heterogeneous cognitive level were compared. 255 7th-graders were grouped into the treatment group and the control group. After the treatment group received the scientific inquiry experimental lessons emphasizing social interaction and the control group received traditional lessons for one year, academic achievement, ability for scientific inquiry, and learning motivation were examined. These inquiry experiments were composed of four steps which are eliciting, familiarizing, constructing and bridging. And students can interact with peers and teachers through the process of relating observed phenomena to concept, constructing experiment procedure, and eliciting results. The ANCOVA results revealed that there were significant effects of science inquiry experiments emphasizing social interaction on the academic achievement, the ability for scientific inquiry and the learning motivation of the students. The significant academic achievement of the students in most of the cognitive levels, if not all, was found and degree of improvement in the ability for scientific inquiry was lower than that in the academic achieve3ment. Concerning the effects according to the way of organizing small groups, there were significant improvement in academic achievement and learning motivation of the group in homogeneous cognitive level compared to the group in heterogeneous cognitive level. These results indicate that social interaction in learning is important and it has positive influences on the improvement in academic achievement and ability for scientific inquiry of students.

      • 췌장의 대낭성 장액성 낭선종 : 2예 보고

        김한성,최현준,주미,장선희,곽지은,김철남 인제대학교 2006 仁濟醫學 Vol.27 No.-

        Typical serous cystadenoma of pancreas is formed by many microcysts, of which diameter are less than 2cm. Recently, rare variants are also reported as macrocystic, unicystic, or multicentric. Macrocystic serous cystadenoma is diffcult to differentiate from pseudocyst, mucinous cystadenoma and other cystic mass having macrocysts. As these lesions have different symptoms, methods of treatment, and prognoses, it is important to diagnose and treat correctly. We report 2 cases which diagnosed as macrocystic serous cystadenoma with stressing scarcity value and clinical importance.

      • KCI등재

        정신분열증 환자에서 주관적 음성증상경험의 임상적 의의

        김지웅,김찬형,구민성,손석한,박진철,최문종,이은철,윤도준,이홍식 대한신경정신의학회 1999 신경정신의학 Vol.38 No.1

        연구목적 : 현재까지 정신분열증의 음성증상평가는 주로 객관적인 평가에만 의존해왔기 때문에, 환자들이 주관적으로 직접 경험하는 음성증상의 평가는 경시된 경향이 있었다. 그러나 실제 많은 정신분열증 환자들은 음성증상을 자가하고 있다. 특히, 개관적인 양성 및 음성증상이 관찰되지 않는 경우에도 환자 본인은 음성증상으로 괴로워한다는 이전의 연구보고들이 있었다. 따라서 저자들은 주관적인 음성증상경험과 개관적인 양성증상 및 음성 증상, 우울증상, 불안증상, 추세외로증상과의 상관성을 알아봄으로써 정신분열증의 정신병리에 있어 주관적 음성증상의 존재를 규명하고, 정신분열증 정신병리의 발생기전을 유추해보며 이차적 음성증상과의 관계를 규명하고자 하였으며. 이러한 연구가 정신분열증 정신병리를 이해하는데 도움을 줄 수 있을 뿐 아니라 환자를 공감적으로 이해하는데 도움을 줄 수 있을 것으로 생각되어 본 연구를 시행하였다. 방 법 : DSM-Ⅳ 진단기준의 정신분열증 진단기준에 해당하는 환자를 대상으로 하였다. 주관적인 음성증상의 평가를 위해서 Scale for the Subjective Experience of Negative Symptoms : Korean version(KSENS)을 이용하였고, 개관적인 정신분열증 정신병리의 평가는 Positive and Negative Syndrome Scale(PNASS)를 이용하였다. 우울증상, 불안증상, 추세외로증상의 평가를 위해서 각각 Hamilton Rating Scale for Depression(HAM-D), Hamilton Rating Scale for Anxiety(HAM-A), Extrapyramidal Symptoms Rating Scale(ESRS)을 이용하였다. 각 정신병리척도 점수간의 상관성은 Spearman 상관계수를 이용하여 분석하였다. 결 과 : K-SENS 24항목 중에서 환자가 이를 불편한 것으로 경험하고 있는 항목의 비율과 PANSS 양성척도점수 사이에는 유의한 상관점이 있었으며 (r=-0.40, p〈0.05), 양성증상 중에서도 특히 과대성(r=-0.46, p〈0.05), 의심/피해(r=-0.34, p〈0.05), 적개심(r=-0.52, p〈0.05) 등의 증상과 유의한 상관관계를 보였다. K-SENS 24 항목 중에서 환자가 이를 불편한 것으로 경험하고 있는 항목의 비율과 PANSS 전체점수(r=-0.25, p〉0.05), PANSS 음성척도점수(r=-0.20, p〉0.05), PANSS 일반정신병리척도(r=-0.08, p〉0.05),와는 각각 유의한 상관성이 없었다. K-SENS 24항목 중에서 환자가 이를 불편한 것으로 경험하고 있는 항목의 비율과 HAM-D 점수(r=-0.01, p〉0.05), HAM-A 점수(r=-0.11, p〉0.05), ESRS 총점(r=0.34, p〉0.05)은 각각 유의한 상관성이 없었다. 결 론 : 본 연구결과에서, 정신분열증 환자들이 불편한 것으로 경험하는 주관적 음성증상과 과대성, 의심/피해, 적개심 같은 양성증상은 역상관관계가 있었으며, 이러한 결과를 바탕으로 양성증상이 주관적으로 불편하게 느끼는 음성증상에 대한 가능성과, 혹은 양성증상이 심할 경우, 이에 압도되어 음성증상을 주관적으로 느끼지 못할 수 있다는 가능성이 시사되었으며, 향후 종적인 연구를 통해 이를 규명해 볼 필요성이 제시되었다. 주관적인 음성증상경험과 우울증상, 불안증상, 추세외로 증상과는 상관성이 없는 것으로 나타나서 이들 증상과는 독립적인 증상임을 시사한다. Objective : Since the evaluation of negative symptoms has depended on the clinician's objective observation, the patients subjective experience of negative symptoms has been neglected. However, in fact, a lot of patients are aware of their negative symptoms. There are several reported suggesting that patients suffer from the subjective experiences of their deficit symptoms, even though the objective positive and negative symptoms cannot be observed. Under these circumstances, we have attempted this study with the idea that it would be helpful in understanding the psychopathology of schizophrenia. Also it would help clarifying the relationship between subjective experience of negative symptoms and objectives positive and negative symptoms, depression anxiety symptoms, and extrapyramidal symptoms. Method : All the 37 patients satisfied the diagnostic criteria of DSM-Ⅵ for schizophrenia. The subjective experiences of negative symptoms were evaluated using Scale for the Subjective Experience of Negative Symptoms : Korean version(KSENS), and for the depression, anxiety, extrapyramidal symptoms, we used Hamilton Rating Scale for Depression(HAM-D), Hamilton Rating Scale for Anxiety(HAM-A), and Extrapyramidal Symptoms Rating Scale(ESRS). The correlation between each psychopathology was tested by calculating Spearman correlation coefficient. Results : There was a significant correlation between the ratio of items experienced as uncomfortable symptoms among 24 items of K-SENS, and the score of PANSS positive subscale(γ=-0.40, p〈0.05), Among the positive symptoms, grandiosity(γ=-0.46, p〈0.05), suspiciousnes/persecution(γ=-0.34, p〈0.05), and hostility(γ=-0.52, p〈0.05) showed a significant correlation with the ratio of items experienced as uncomfortable symptoms among 24 items of K-SENS. There was no significant correlation between the ratio of items experienced as uncomfortable symptoms among 24 items of K-SENS, and PANSS total score(γ=-0.25, p〉0.05), or negative subscale score(γ=-0.20, p〉0.05), or general psychology subscale score(γ=-0.08, p〉0.05), respectively. There was no significant correlation between ratio of items experienced as uncomfortable symptoms among 24 items of K-SENS, and HAM-D(γ=-0.01, p〉0.05), or HAM-A(γ=-0.11, p〉0.05), ESRS(γ=0.34, p〉0.05), respectively. Conclusion : These revealed that the negative correlation between the subjective negative symptoms experienced as an uncomfortable ones and the objective symptoms such as grandiosity, suspiciousness/persecution, and hostility. From these results, the possibility that positive symptoms are used as a defense to hide from the negative symptoms because they are overwhelmed by their positive symptoms, is suggested. These results also suggest that subjective experiences of negative symptoms are independent from depression, anxiety and extrapyramidal symptoms.

      • Benson's Group Additivity Method를 이용한 염화다환방향족 화합물의 열역학적물성치 평가와 생성반응경로에 관한 연구

        임지선,박자영,원양수,최성필 嶺南大學校 環境問題硏究所 1995 環境硏究 Vol.15 No.1

        도시폐기물 소각시설에서 다이옥신류는 chlorobenzene, chlorophenols, PCBs등의 염소성분이 포함된 방향족화합물과 함께 폐기물의 소각처리시 불완전 연소로 인해 주로 생성된다. 이들 다이옥신 생성에 대한 반응메카니즘의 예측에 필요한 다이옥신을 형성하는 전구물질인 분자 및 radical의 정확한 열역학적 물성치를 평가하기 위해 Benson's group additivity method에서는 고려되지 않는 Cl, F, OH, CH3등과 같은 2개 이상의 치환기가 결합된 방향족화합물에 대한 computer code인 THERM을 이용하여 엔탈피(Hf), 엔트로피(St), 열용량(Cp)을 평가하였다. 또한 이와 같은 열역학적 물성치 평가법의 신뢰성을 검토하기 위해 다양한 방향족화합물에 대한 실험적으로 측정된 문헌치와 평가치와의 절대오차는 para-cresol의 0.02kcal/mole에서 hexamethylbenzene의 3.46kcal/mole로 좁은 범위를 나타내었다. 또한 다이옥신을 생성하는 전구물질들의 열역학적 물성치를 THERM을 이용해 간접적으로 평가함으로써 다이옥신을 형성하는 주요 생성반응 경로에 대해 살펴본 결과는 다이옥신을 형성하는 기초반응(elementary reaction)중 욤소수가 많은 반응물질일수록 반응이 더 잘 일어남을 알수 있었다. Chlorinated dioxins are often observed in effluent from oxidation or incineration such as chlorobenzenes, chlorophenols and PCBs. It would be of significant value to have an accurate and fundamental understanding of the mechanism for dioxin formation, in addition to the knowledge of dioxin thermodynamic properties, in order to assist in the design of stategies to effectively control or reduce emissions of these compounds. Very little has been published on the thermodynamic properties and elementary reactions which lead to formation of dioxins. Benson group additivity method, when used for the estimation of thermodynamic properties of molecules, does not account for all interactions between functional groups or atoms on aromatics, such as chlorines, hydroxyl or ether linkages. Therefore thermodynamic properties of dioxins are estimated by THERM based on Benson's group additivity method corrected by interactions group. Absolute errors between our predictions and literature values range from a low of 0.02 kcal/mole for paracresol to a high 3.46kcal/mole for hexamethylbenzene. We use these thermodynamic calculations to show the feasibility of several elementary reaction pathways leading to dioxin formation, where the presence of chlorine acts to enhance or lower the Gibbs free energy of reactions.

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