흰쥐에서 고칼리 식이에 의해 유도된 지방간 형성에 미치는 감귤발효 추출액의 영향

진영준,문상욱,김기옥,박덕배,김세재 제주대학교 생명과학연구소 2003 제주생명과학연구 Vol.6 No.1

Male Sprague-Dawley rats were orally treated with low and high-doses (50mg and 100mg/Kg of body weight) of either fermented-citrus extract or citrus extract dissolved in 20% ethanol during 6 weeks. The body weight, the level of plasma total choresterol were slightly reduced in higher dose(100 mg/Kg of body weight) of fermented-citrus extract comparing with other groups. but was not significantly different. The fat liver formation induced by high-fat diet were significantly reduced in rats administrated with fermented citrus-extract. This result suggest that fermented-citrus extract have hepatoprotective activity against high-fat diet induced fatty liver.

투기, 구기, 라켓경기 선수의 피하지방 두께와 근질량 비교분석

최명진,안세옥 경희대학교 사회체육연구소 1996 體育科學論叢 Vol.- No.9

The purpose of this study was to discriminate the characteristics of muscle mass and skinfold thickness in made cdlesiate athletes 120 athletes from three parts of sport events who were 20∼22 years old (mean 21 age years). with ape of 21 years ANOVA. swbjects were 120 1. The maximal upper arm girth means corrected for the tricep skinfold thickness were ranged from 26.05 for the taekwondo to 31.41 for the judo. Judo was one of the greatest maximal upper arm girth means corrected for the tricep skinfold thickness in all sports (rugby, table tennis, handball, badminton, taekwondo). By scheffe test, judo and rugby is different from other sports. 2. The maximal forearm girth means were ranged from 26.13 for the taekwondo to 29.28 for the judo. Judo was one of the greatest maximal forearm arm girth means corrected for the tricep skinfold thickness in all sports (rugby, table tennis, handball, badminton, taekwondo). By scheffe test, rugby was different from taekwondo, Judo was different from taekwondo, handball, badminton, table tennis. 3. The mid thigh girth means corrected for the front thigh skinfold thickness were ranged from 50.75 for the table tennis to 57.09 for the rugby. Rugby was one of the greatest maximal mid thigh girth means corrected for the tricep skinfold thickness in all sports (rugby, table tennis, handball, badminton, taekwondo). By scheffe test, judo was different from table tennis. Rugby was different from taekwondo, handball, badminton, table tennis. 4. The maximal calf girth means corrected for the calf skinfold thickness were ranged from 34.69 for the Table tennis to 39.61 for the rugby, Rugby was one of the greatest maximal calf girth means corrected for the tricep skinfold thickness in all sports (rugby, table tennis, handball, badminton, taekwondo). By scheffe test, rugby was different from badminton. judo different from taekwondo, handball, badminton, table tennis. 5. The muscle mass were ranged from 41.88 for the table tennis to 53.07 for the rugby. Rugby had significantly greater muscle mass than other sports (judo, handball, taekwondo, badminton, table tennis). By scheffe test, rugby was different from taekwondo and judo was different from other sports (handball, taekwondo, badminton, table tennis). 6. The percentage of body mass was ranged from 61.29 for the Judo to 64.34 or the handball. Handball had significantly greater a percentage of body mass than other sports (badminton, taekwondo, rugby, table tennis, judo). By scheffe test, fudo is only different from handball. 7. The sum of skinfold thickness was ranged from 24.9mm for the taekwondo to 36.9mm for the judo. Judo had significantly greater the sum of skinfold thickness than other sports (rugby, badminton, table tennis, handball, taekwondo). By scheffe test, Judo is different from taekwondo and handball.

디젤엔진의 배기시스템에서 산화 촉매가 극미세입자 발생에 미치는 영향에 관한 실험적 연구

김세준,이해철,차경옥,이진욱 明知大學校 産業技術硏究所 2006 産業技術硏究所論文集 Vol.25 No.-

Recently, the Diesel PM's number concentration emitted by Diesel internal combustion engine has focused on attention because this particle matters are suspected being hazardous of human health. In this study, particle condensations and size distribution were measured in the exhaust system of a turbo charged diesel engine, equipped with a diesel oxidation catalyst(DOC). A scanning mobility particle sizer(SMPS) system was applied to measure the particle number and size concentration of diesel exhaust particles, at the front and rear position of diesel oxidation catalyst(DOC) along the engine speed and load conditions. As the result, the effects of diesel oxidation catalyst(DOC) on the Diesel nano particle number and size distribution will be represented in this study.

곰쓸개 복용 후 발생한 육안적 혈뇨와 신유두부 괴사증 1예

김우진,한민석,김수항,박인형,박진석,선제형,홍세인,박옥영,신정현,이숭,신병철 朝鮮大學校 附設 醫學硏究所 2006 The Medical Journal of Chosun University Vol.31 No.3

Renal papillary necrosis occurs most commonly in association with urinary tract infection, diabetes mellitus, sickle cell disease, vascular disease, and analgesic nephropathy. Clinical presentation may be related to symptoms of pyelonephritis such as flank pain, renal colic, hematuria, Proteinuria, recurrent fever. The necrotic tissue may be sloughed off, and the diagnosis can sometimes be made by finding piece of renal medullary tissue in the urine. Pyelography may demonstrate cavities and sinuses in the resion of papillae. Anuria & oliguria can lead to the acute renal failure, and especially prognosis and progress may be affect influenced by urinary infection. We report a case of renal papillary necrosis with ingestion of bear gallbladder. On pyelography, Persistent contrast is diagnostic clue of renal papillary necrosis. This case is not be related to urinary tract infection, but occurred acute renal failure. Expectant treatment was gone.

패류중 중금속함량에 관한 연구

신현수,허옥순,이진하,김세은,주인선,신동우,강석종,박만종,김지연,김근희,강숙경,정래석,허숙진,소유섭,최장덕,문병우,김진수 식품의약품안전청 2001 식품의약품안전청 연보 Vol.5 No.-

본 연구는 패류중 중금속함량 측정을 위한 분석효율이 높고 간편한 분해법을 찾아내어 그 방법에 의끓 유종중인 패류중 중금속함량을 파악하고자 수행하였다. 시료를 분해시키는 Microwave와 습식, 건식회법을 비교한 결과 변형습식회화르가 가장 적합하였다. 변형습식회차딘는 려린0,3+C104+H2SOf의 혼찰산을 쪼 · j 1 (v/v)의 비율로 혼합하여 사용하였 을 때 회수을 Pb린틴. Cd 97.8, Cu 94.2, Zn 92.8%를 나타내었근 분해시간은 2~2.5시간 소요되었다. 유통중인 패류중 중금속함량 」최소~최대(평균), mgAgl 은 Pb 0.028~o.528(0.153), Cd 0.OO7~1,832(0.587), Cu 0.360~37.375(4.6691, Zn 6.317~233.2iO(38.881), Hg 0.001 ~O.151(0.012)mg/ltg으로 나타났다. 또한 유통중인 5종의 패류중 중금속평균항량이 생산지 하재지역에서 구입한 패류에 비해 모든 중금속언써 약간 높은 함량을 보였으나 오염된 수준이 아닌 자연함유량수준이었다. This study was conducted to improve the digestion method for the determination of heavy metals in shellfishes and to estimate the contents of heavy metal in commercial shellfishes by their digestion method. This digestion method was compared microwave with wet and dry ash digestion for shellfish samples, obtained results showed that the modified wet ash Ⅱ digestion was convenient and easy to use. For the modified wet ash Ⅱ digestion, The mixed acid of HNO₃+HClO₄+H₂SO₄(25:5:1, v/v) was used. Under this condition, Recoveries were Pb 94.3, Cd 97.8, Cu 94.2 and Zn 92.8% and digestion time was ∼2.5 hours. The contents of heavy metal [minimum∼maximum (mean), mg/kg in commercial shellfishes were as follows ; Pb:0.028∼0.528(0.153), Cd:0.007∼1.832(0.587), Cu:0.360∼37.375(4.669), Zn:6.317∼233.250(38.881), Hg:0.001∼0.151(0.013). The contents of heavy metal in commercial shellfishes of five species were slightly greater than those of shellfishes purchased at Hajae. There was no great difference between the contents of heavy metal of Hajae and those of shellfishes purchased at Whole market.

식품유해세균에 대한 식초의 항균효과

우승미,장세영,김옥미,윤광섭,정용진 한국식품저장유통학회 ( 구 한국농산물저장유통학회 ) 2004 한국식품저장유통학회지 Vol.11 No.1

본 연구에서는 시판되고 있는 식초를 이용하여 6종의 식품 유해세균에 대한 항균력을 비교하였다. 그 결과, 감식초와 현미식초는 합성식초에 비해 S. aureus, M. luteus, S. enteritidis 및 E. coli에서 항균 활성이 높게 나타났으며, 현미식초가 감식초에 비해 식품유해세균에 대한 항균활성이 비교적 더 높게 나타났다. 현미식초의 농도에 따른 항균활성을 조사한 결과 5종의 그람양성 세균 및 음성 세균 모두 10μm/mL 이상의 농도에서 생육이 거의 억제되었으나, V. parahaemolyticus는 15 μm/mL 농도에서 생육이 거의 정지되어, 현미식초는 식품 부패균과 대장균 생육억제에 우수한 것으로 나타났다. 식초처리에 의한 미생물의 형태 변화를 전자 현미경으로 관찰한 결과 S. aureus, E. coli 모두 세포가 팽윤되고 일부 세포벽이 완전히 파괴된 형태를 관찰할 수 있어 식초처리로 인해 세균의 생육이 억제되는 것을 알 수 있었다. We investigated antimicrobial effects of commercial vinegar on the harmful food-born organisms. As a result, antimicrobial effects of brown rice vinegar showed stronger than persimmon and artificial vinegar. In 10μL/mL concentration of brown rice vinegar was completely inhibited about 5 strains except for V. parahaemolyticus, it was inhibited 15 μL/mL concentration. Therefore vinegars were effective for inhibition acitivity against foodborne organisms. S. aureus and E. coli treated with 25μL/mL concentration brown rice vinegar was observed by scanning electron micrographs(SEM). The cells were expanded and a part of cell wall was completely destructed by brown rice vinegar.

정맥주입 전문간호사가 삽입한 말초삽입형 중심정맥관(PICC) 사용 결과에 대한 후향적 분석

박정윤,박광옥,백미경,김세라,권혜리,양수진 대한기초간호자연과학회 2004 Journal of korean biological nursing science Vol.6 No.1

Background : Intravenous(Ⅳ) access is becoming an increasingly important part of health care today. The current drive for clinical effectiveness and cost-effective health care serves to increase the need for reliable vascular access. Venous access devices were developed to overcome problems associated with limited peripheral access and frequent venipuncture in patients with long-term therapy. Although the peripherally inserted central catheter(PICC) have become popular during recent years in USA, its procedure is rare in Korea. Purpose : The goal of this study was to analyze the PICC inserted patient data by Ⅳ CNS intervention. Method : A Total of 62 PICCs were inserted into 51 patients by the Ⅳ CNS during a 10-month period form November, 14, 2002, to October 2, 2W2. Data was obtained retrospectively through chart review. Result : The patient population included 34(54.8%) men and 28(45.2%) women, with a mean age 50.6 years. The main indication for PICC placement was to access vein in poor peripheral venous status(40.3%). The mean served interval for PICC insertions was 16.7 days(range, 2~61 days). The reasons for removal were completed therapy in 18 cases(29.0%), patient death in 13 cases(21.0%), and mechanical or functional PICC problem in 10cases(16.1%). The three PICCs removed for presumed infection, and one had only positive tip cultures(0.2%). Conclusion : PICCs are rapidly growing popularity and required an extended course of Ⅳ therapy.

질소 및 셀레늄 분위기 열처리가 나노 입자 Cu(In, Ga) Se₂ 광흡수층의 치밀화에 미치는 영향

김기현(Kim, Ki-Hyun),안세진(Ahn, Se-Jin),전영갑(Chun, Young-Gab),박병옥(Park, Byun-Ok),윤경훈(Yoon, Kyung-Hoon) 한국신재생에너지학회 2005 한국신재생에너지학회 학술대회논문집 Vol.2005 No.06

나노 입자 분무 기법을 이용한 Cu(In,;Ga)Se₂ (CIGS) 광흡수층 제조 기법은 고진공 장치를 사용하지 않는다는 점에서 대면적 저가형 CIGS 태양전지 양산에 적합한 차세대 기술로 인식되고 있다. 그러나 일반적으로 스프레이 된 상태의 CIGS충 자체는 태양전지 제조에 적합하지 않은데 이는 스프레이 막의 다공성 구조 때문이다. 본 연구에서는 나노입자 분무 기법을 이용하여 증착한 CIGS 광흡수층막을 질소 또는 셀레늄 분위기에서 열처리함으로써 태양전지 제조에 적합한 치밀한 구조의 CIGS 광흡수충을 제조하고자 하였다. 실험 결과, 질소 분위기 500?C의 온도에서 1시간 열처리하여도 CIGS 나노 입자의 성장은 거의 일어나지 않는 것으로 나타났다. 반면 셀레늄 분위기 500?C의 온도에서 30분 열처리시 입자 크기가 1{mu}m이상인 치밀한 광흡수층을 얻을 수 있었다. 본 결과는 CIGS 나노 입자의 입자 성장 반응에서 열에너지 단독에 의한 표면 에너지 감소 효과는 미미하며 셀레늄 증기의 역할이 더욱 크다는 것을 의미하는 것이다.

새로운 HVT 성장방법을 이용한 CIGS 결정성장

이강석,전헌수,이아름,정세교,배선민,조동완,옥진은,김경화,양민,이삼녕,안형수,배종성,하홍주,Lee, Gang-Seok,Jeon, Hun-Soo,Lee, Ah-Reum,Jung, Se-Gyo,Bae, Seon-Min,Jo, Dong-Wan,Ok, Jin-Eun,Kim, Kyung-Hwa,Yang, Min,Yi, Sam-Nyeong,Ahn, Hyung-Soo 한국결정성장학회 2010 한국결정성장학회지 Vol.20 No.3

높은 광흡수 계수를$(1{\times}10^5cm^{-1})$ 가지는 CIGS는 Ga의 비율에 따라서 밴드갭을 조절할 수 있다는 장점을 지니고 있다. CIGS의 밴드갭은 Ga의 비율에 따라 $CuInSe_2$(Eg: 1.0 eV)에서 $CuGaSe_2$(Eg: 1.68 eV)까지의 범위에 존재하며, 태양전지에 서 이상적인 fill factor 모양을 가지도록 Ga의 비율을 높게 조성한다. CIGS 흡수층을 제작하는 방법에는 co-evaporator 방식이 가장 널리 사용되며 연구되고 있다. 이에 본 연구에서는 수평 형태의 hydride vapor transport (HVT)법을 고안하여 CIGS 나노 구조 및 에피성장을 시도하였다. HVT법은 $N_2$ 분위기에서 원료부의 CIGS 혼합물을 HCl과 반응시켜 염화물 기체상태로 변환 후 growth zone까지 이동하여 성장을 하는 방식이다. 성장기판은 c-$Al_2O_3$ 기판과 u-GaN을 사용하였다. 성장 후 field emission scanning electron microscopy(FE-SEM)과 energy dispersive spectrometer(EDS)를 이용하여 관찰하였다. The Cu$(In_{1-x}Ga_x)Se_2$ is the absorber material for thin film solar cell with high absorption coefficient of $1{\times}10^5cm^{-1}$. In the case of CIGS, the movable energy band gap from $CuInSe_2$ (1.00 eV) to $CuGaSe_2$ (1.68 eV) can be acquired while controlling Ga contain ratio. Generally, the co-evaporator method have used for development and fabrication of the CIGS absorption layer. However, this method should need many steps and lengthy deposition time with high temperature. For these reasons, in this paper, a new growth method of CIGS layer was attempted to hydride vapor transport (HVT) method. The CIGS mixed-source material reacted for HCl gas in the source zone was deposited on the substrate after transporting to growth zone. c-plane $Al_2O_3$ and undoped GaN were used as substrates for growth. The characteristics of grown samples were measured from SEM and EDS.

가미소요산의 새로운 제형에 대한 항산화 활성 및 항염증 효능평가

최혜민 ( Hye-min Choi ),김세진 ( Se-jin Kim ),김인수 ( In-su Kim ),이지범 ( Ji-beom Lee ),김종범 ( Jong-beom Kim ),문성옥 ( Sung-ok Moon ),이화동 ( Hwa-dong Lee ) 대한본초학회 2016 大韓本草學會誌 Vol.31 No.6

Objectives : Gamisoyosan (GMS) is a useful prescription for treating insomnia, dysmenorrhea and infertility induced by a stress. Also, GMS has been used traditionally to improve systemic circulation and biological energy production. The purpose of this study was to assess the anti-oxidant activity and anti-inflammatory effects of Gamisoyosan Formulation (Soft extract, GMS-SE). Methods : The biological activities such as anti-oxidant and anti-inflammatory effects were measured through cell line-based in vitro assay. We investigated the anti-oxidant properties of GMS-SE on the 1,1-diphenyl- 2-picryhydrazyl (DPPH) radical, contents of total flavonoid and polyphenol. GMS-SE compared to butyl hydroxy anizole (BHA). Furthermore, based on this result the anti-inflammatory effects of GMS-SE have verified by mechanism from LPS- treated Raw264.7 macrophages. Results : The anti-oxidant activities of GMS-SE increased markedly, in a dose-dependent manner. The GMS-SE showed significant scavenging activity (GMS-SE 500 ㎍/㎖ : 32.77±1.65%, GMS-SE 1000 ㎍/㎖ : 45.06±1.04% and BHA 100 ㎍/㎖ : 39.25±2.41% for DPPH assay). and, The total phenolic compound and flavonoids contents of GMS-SE were 73.93±6.87 ㎍/㎎ and 698.75±6.78 ㎍/㎎. GMS-SE which is LPS has diminished in the LPS-induced release of inflammatory mediators (NO, iNOS, COX2 and PGE2) and pro-inflammatory cytokines (TNF-α, IL-6 and IL-1β) from the RAW264.7 macrophages. Moreover, GMS-SE inhibited the activation of phosphorylation of p38 and ERK MAPKs by induced LPS. Conclusion : The present results indicate that GMS-SE has an anti-oxidant and anti-inflammatory properties, therefore may be beneficial in diseases which related to oxidative stress-mediated inflammatory disorders.