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      • SCOPUSKCI등재

        순환 유동층의 수역학적 특성 및 석탄연소 특성

        신병철,김상돈,고영범 한국화학공학회 1984 Korean Chemical Engineering Research(HWAHAK KONGHA Vol.22 No.5

        순환유동층(7.8㎝-내경 × 250㎝-높이)내의 석탄-공기 계의 흐름특성을 실온에서 측정하였고, 석탄연소시의 연소효율과 유동층 높이에 따른 온도분포를 결정하였다. 발열량이 4.870㎉/㎏인 국내 무연탄은ㄹ 사용하여 흐름특성은 석탄의 평균입자경을 0.205, 0.395 및 0.71㎜로 바꾸어서 측정하였으며 석탄연소실험은 0.71㎜입자를 사용하였다. 기포층과 난류층 흐름의 경제속도(transition velocity) 및 난류유동층과 고속유동층의 경계속도인 수송속도(transport velocity)를 결정하였다. 난류유동층흐름에서의 석탄연소효율은 기포층흐름때 보다 높게 나타나며 낮은 온도에서도 쉽게 정상상태를 유지할 수 있었다. 석탄연소효율은 과잉공기양이 증가함에 따라 기포유동층 및 난류유동층에서 다같이 증가하며 난류유동층에서의 유동층높이에 따른 온도분포는 기포층유동층보다 더 균일하게 측정되었다. In a circulating fluidized bed (7.8 ㎝-ID × 250 ㎝-high), flow regimes of coal-air system at room temperature and coal combustion efficiency and temperature profiles along the bed height have been determined. An anthracite domestic coal having heating value of 4,870 ㎉/ ㎏ was employed. Coal particle sizes were varied 0.205, 0.395 and 0.71 ㎜ for flow regime and 0.71 ㎜ for coal combustion studies. The transition velocity between bubbling and turbulent beds and the transport velocity between turbulent and fast beds have been determined. In a circulating fluidized bed, combustion efficiency was higher in the turbulent bed than that in the bubbling bed. Steady combustion operation can be easily maintained at much lower temperature in the turbulent bed than in the bubbling bed.

      • KCI등재
      • KCI등재
      • KCI등재

        혈류 내 안정성 향상을 위한 빗 모양 고분자로 개질된 리포솜

        신병철,송충길,황태원,성하수,박은석,Sin, Byeong-Cheol,Song, Chung-Gil,Hwang, Tae-Won,Seong, Ha-Su,Park, Eun-Seok 대한화학회 2006 대한화학회지 Vol.50 No.3

        혈류 내에서 리포솜의 안정성을 향상시키기 위해 지질-고분자 유도체를 지질 이중층에 도입하거나 친수성 고분자를 리포솜에 결합시켜 리포솜의 표면을 개질하는 방법이 개발되어왔다. 본 연구에서는 비닐 단량체로서 히드록시에틸메타크릴레이트(HEMA)와 히드록시폴리옥시에틸렌메타크릴레이트(HPOEM)를 자유 라디칼 중합하여 측쇄에 다수의 폴리에틸렌옥사이드를 갖는 빗(Comb) 모양 공중합체인 poly(HEMA-co-HPOEM)를 제조하였다. Poly(HEMA-co-HPOEM)를 리포솜의 표면에 결합시키고 혈장 용액 내에서 개질된 리포솜의 특성을 살펴보았다. Poly(HEMA-co-HPOEM)으로 개질된 리포솜의 입자크기는 대조군 리포솜에 비해 약 30 nm 증가하였고 리포솜 표면의 음전하를 차폐하여 제타 포텐셜의 절대값은 감소하였다. 리포솜 내부에 모델약물인 독소루비신(Doxorubicin)의 로딩효율은 ~ 90%로서 리포솜 표면에 결합된 poly(HEMA-co-HPOEM)는 약물의 로딩효율에 영향을 주지 않았다. 혈장 내에서 리포솜의 안정성을 평가한 결과, 빗 모양 고분자로 수식한 리포솜의 입자크기는 증가하지 않았고 단백질 흡착은 대조군 리포솜 또는 폴리에틸렌옥사이드-지질 유도체가 도입된 리포솜(PEG-리포솜)에 비해 감소되어 빗 모양 고분자인 poly(HEMA-co-HPOEM)이 혈류 내 리포솜의 안정성 향상에 효과적임을 확인하였다. To increase the stability of liposomes in blood circulation, surface modification of liposomes by incorporating a lipid-polymer derivative in the lipid bilayer or conjugating a hydrophilic polymer to the liposomal surface has been developed. In this study, the comblike copolymer, poly(HEMA-co-HPOEM), having multiple polyethyleneoxide side chains was prepared by free radical polymerization of hydroxyethylmethacrylate (HEMA) and hydroxypolyoxyethylenemethacrylate (HPOEM) as vinyl monomers. Poly(HEMA-co-HPOEM) was conjugated to the liposomal surface and the characteristics of the modified liposomes in serum were investigated. Conjugation of poly(HEMA-co-HPOEM) to liposomes increased the particle size of the liposomes by 30 nm and decreased the absolute value of zeta potential of the liposomes by shielding the negative charge of liposomal surface. Loading efficiency of model drug, doxorubicin, in liposomes was about 90% and the efficiency was not affected by conjugation of poly(HEMA-co-HPOEM) to liposomes. The particle size of poly(HEMA-co-HPOEM)-conjugated liposomes in serum did not changed and the protein adsorption was lower than that of control liposomes or liposomes containing polyethyleneoxide-lipid derivative (PEG-liposomes). These results suggest that poly(HEMA-co-HPOEM) is efficient for the stabilization of liposomes in blood circulation.

      • KCI등재후보

        傳統造景要素의 視覺的 選好要因에 관한 연구

        신병철 한국전통조경학회 2003 한국전통조경학회지 Vol.21 No.1

        In this paper, visual image structures related to traditional landscape architecture elements of Korea are analized in order to provide them with the concept of space design of modern landscape. The results of present research could be drawn as follows. 1. 31 kinds of typical traditional landscape elements appear to be involved in Korean traditional landscape architecture when viewed in terms of space characteristics, functions and objectives. They are regarded as representatives of the traditional landscape elements. According to the answers to the query, the elements such as Hwa-gye(花階), To-dam(土墻), Bang-ji(方池), Hwa-dam(花墻) are most frequently touched on. 2. The analysis of visual image of ordinary persons as to selected four traditional landscape elements found that the formation factors for visual characteristics are beauty image factor(F1), appearance image factor(F2), emotion image factor(F3), personality image factor(F4), history image factor(F5), and mass image factor(F6). Explanation index regarding six factors mentioned above shows 57.72%, and especially, Eigen value of the beauty image factor(F1) is 4.50, which is relatively high explanation index. 3. Influencing factors on the visual satisfaction from traditional landscape architecture elements are followings; beauty image factor(F1), appearance image factor(F2) and personality image factor(F4). However, it shows that emotion image factor(F3), history image factor(F5) and mass image factor(F6) have no relation to visual satisfaction because the statistical analysis shows that they are not significant.

      • KCI등재

        史實과 虛構로 읽는 『燕丹子』

        신병철 한국중국소설학회 1999 中國小說論叢 Vol.9 No.-

        '스콜라' 이용 시 소속기관이 구독 중이 아닌 경우, 오후 4시부터 익일 오전 9시까지 원문보기가 가능합니다.

        作者未詳的≪燕丹子≫就是創作漢代以前, 代表較早中國文言小說。 主要內容是戰國時代末期燕太子丹, 爲報仇派遣刺客荊軻實行暗殺秦王(卽秦始皇)的故事。 這個故事記載了≪戰國策ㆍ燕策≫、 司馬遷≪史記ㆍ刺客列傳≫、 張華≪博物志ㆍ史補≫和王充≪論衡≫。讀≪燕丹子≫的時候, 應該注視俠文化和天人相應的觀點。 因爲這些觀念包括民間傳說了, 所以근敍述歷史文章不一樣。 敍述歷史文排除了荒唐的故事, ≪史記·刺客列傳≫的文章中沒有黃金投蛙、殺馬進肝、 玉盤盛手的故事。 但是, ≪燕丹子≫包括敍述歷史和民間傳說。≪燕丹子≫篇幅較長, 結構完整, 雖然受了敍述歷史文的影響, 添加民間傳說的虛構性了。 ≪燕丹子≫不屬於小說家類, 屬於小說。

      • 유지 투석중인 만성 신부전환자에서 허혈성 심질환의진단 지표로서의 심장트로닌-I의 유용성

        신병철,강대웅,정지용,류봉관,서영욱,김정인,김범윤,김현리,정종훈 朝鮮大學校 附設 醫學硏究所 2004 The Medical Journal of Chosun University Vol.29 No.1

        Background : Coronary disease is highly prevalent in patient with end stage renal disease (ESRD) and account for much of their observed morbidity and mortality. Troponin-I consistently maintains a high sensitivity and specificity and is most sensitive marker for ischemic heart disease (IHD). Method : We examed 49 hernodialyzed patients (22 male, 27 female) without evidence of acute coronary syndrome (ACS) for 6 months. Biochemical markers were measured in serial predialysis blood samples. For analysis, we used two cardio-specific assays for troponin-T (cTnT) as well as for troponin-I (cTnI) and compared the results with CK-MB (reference value ≤ 4.0 ng/mL) concentration. Results : Myocardial ischemia was observed in 47% (23/49) of patients. cTnT level above 0.1 ng/mL. and cTnI level above 0.5 ng/mL, were observed in 22% (11/49) and 20% (10/49) of patients respectively. cTnI revealed significantly higher positive rate in patients with myocardial ischemia than the patients without myocardial ischemia (43 % vs 30%) (p<0.05). cTnT and CK-MB revealed no difference in positive rate between the patients with and without myocardial ischemia (cTnT : 30% vs 15% and CK-MB : 30% vs 19%). The sensitivity and specificity of cTnI to myocardial ischemia were higher than those of cTnT and CK-MB (sensitivity 43% vs 30% and 30%. specificity 100% vs 85% and 81%). Conclusion: Both cTnT and cTnI are useful in ruling out myocardial injury in chronic renal failure patients. But. cTnI is a more sensitivity and excellent specificity of ischemic heart disease than cTnT and CK-MB in hemodialyzed patients. In patients with ischemic heart disease, the presences of DM and advanced age were higher than those in patients without ischemic heart disease (p<0.05). Among the baseline characteristics old age, elevated LDH and diabeties were significant more frequent in the patients with elevation of cardiac troponin-I (p>0.5 ng/mL) than those with cardiac troponin-I (p<0.5 ng/mL), p=0.038, p=0.049, and p=0.045, respectively. Our results suggest that these cTnI is the potential diagnostic marker for the prediction of IHD in ESRD patients.

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