불소화계면활성제 함유 DPPC/Cholesterol 및 DPPG/Cholesterol 베지클의 BSA(bovine serum albumin)친화성 연구

권경옥,김명자,김현영 숙명여자대학교 자연과학연구소 1998 자연과학논문집 Vol.- No.9

본 연구에서는 항원(antigen). 항체(antibody) 등을 삽입시켜 자극반응성 베지클을 제조의 예비실험으로 대표적인 생체 단백질 BSA(bovine serum albumin)와 베지클의 친화도에 관해 알아보았다. DPPC(dipalmitoylphosphatidylcholine)/Chol, DPPG(dipalmitoylphos-Phatidylglycerol)/Chol,DPPC/Chol/FFS(ammonium pentadeca-fluorooctyrate)/FS(sodium bis(1H,1H,2H,2H-heptadecafluorodecyl)-2-sulfosuccinate), DPPG/Chol/ FFS/FS의 4종의 베지클을 제조하고, 제조된 4종의 베지클에 대해 column chromatography 법에 의해 BSA와의 흡착 여부를 확인했다. 실험 결과, 각 계의 베지클 입자크기는 BSA의 흡착으로 인해 감소하는 것으로 나타났고, 감소하는 정도는 DPPC/Chol와 DPPG/Chol에서 큰 것으로 나타났다. 반면, 제조된 계의 제타전위(ξ-Potential)값에는 거의 변화가 없었다. BSA와의 결합친화력의 비교에서는 DPPC/Chol. DPPG/Chol. DPPC/Chol/FFS/FS. DPPG/Chol/FFS/FS 순으로 낮아진다는 결과를 얻었다. 이들 실험결과에 바탕하여, 위의 4종의 베지클과 BSA와의 결합친화력에 대해 베지클의 표면전하와 베지클 막의 밀집성(compactness)이 영향을 미친다는 결론을 얻었다. The purpose of this study is to prepare a functional vesicle for the possible use as a biosensor. In this work, we have performed a preliminary experiment for biosensor, Four different systems of vesicle have been prepared with the composition of DPPC(dipalmitoylphosphatidylcholine)/Chol, DPPG (dipalmitoylphos-phatidylglycerol)/Chol, DPPC/Chol/FFS(ammonium pentadecafluoro-octyrate)/FS(sodium bis(1H,1H,2H,2H-heptadecafluorodecyl)-2-sulfosuccinate) and DPPG/Chol/FFS/FS. By use of column chromatography, it was found that BSA has been adsorbed onto the vesicle structure. The size of vesicle was found to decrease as adsorption occurs between the two species and the extent was greater in the systems of DPPC/Chol and DPPG/Chol. However, the δ-potential of the system remained essentially unchanged. The affinity of vesicle to BSA was found to decrease in the order of DPPC/Chol, DPPG/Chol, DPPC/Chol/FFS/FS and DPPG/Chol/FFS/FS. Based on these findings, it may be concluded that the affinity of vesicles onto BSA was affected by the surface charge and the compactness of vesicle.

신규간호사를 위한 맞춤형 멘토 프로그램(새싹프로그램)의 개발 및 적용 : 일개 대학병원 중환자실을 중심으로

권은옥,조정숙,송경자,최스미,장선주,김주희,박승현,신효연,유미,김정아 대한간호학회 간호행정학회 2009 간호행정학회지 Vol.15 No.4

Purpose: The purpose of this study was to develop specialized mentor program to improve adaptation for new nurses of intensive care unit and to identify the effect of the program on early resignation rate. Methods: The study adopted nonequivalent control group, non synchronized design. Based on the identification of problems and the needs of new nurses, a 6 month specialized mentor program was developed. The program was consisted of three parts; developing knowledge, improving interpersonal relationship and increasing coping competency for emergency situation. Data were collected between July 2006 and 2008 from 37 nurses and the early resignation rate was compared before and after the implementation of the mentoring program. Results: Early resignation rate of the nurses who received the mentor program was significantly lower than that of the nurses who didn't. The resignation rate within 1 year dropped from 44.5% to 8.3%(p=.034). Conclusions: The specialized six month mentoring program was effective in reducing early resignation rate.

구조화된 환자교육에 대한 연구논문 분석 : 고혈압 환자를 중심으로 forcused on the patients with hypertension

박청자,이경희,고효정,권영숙,김정남,박영숙 대한보건협회 2003 대한보건연구 Vol.29 No.2

This study was conducted to analyze the nursing research methodology and the key concepts used in articles related hypertension published in the RICH. The purpose of this study was for reflecting the trends of the research on the structured patient education focused the hypertensives. The results were as following. 1. There were 119 research studies related hypertension in RICH from 1994 to 2002. The number increased in 1997. Research studies of 98 have done since 1997 and it is 82% of the total research studies. 2. The most of the research studies are non-degree research studies. Research studies with fund have been rapidly increased in 2000 year. 3. The prevailing research design were the non-experimental design, quasi-experimental and pre-experimental designs in order. 4. The data collection method used most often physiologic measures(32.8%). 5. The domain of the key concepts that prevailed was health domain(51.8%), nursing domain(22.9%), and human being domain(20.5%) in order. And environmental domain (4.8%) were relatively low.

건대추를 이용한 소금절임과 품질

정자림,김미경,권상호,김미정 대구효성가톨릭대학교 식품과학연구소 1993 식품과학지 Vol.5 No.-

건대추를 이용한 소금절임과정중 품질변화를 조사한 결과는 다음과 같다. 절임중의 증량변화는 온도와 염도의 차이에 따라 상당한 차이를 나타내었으며 건대추중량의 260-280%이상의 증가현상이 나타날 경우는 조직이 흐트러지고 심한 연화현상을 동반하였다. 특히 온도가 30℃로 높을 경우에 이러한 현상이 두드러지게 나타났다. 절임온도가 10℃일때 그리고 염농도가 10%일때가 바람직하였다. 절임액으로의 물질의 용출정도는 염도가 높고 온도가 높을 수록 거의 비례적으로 높았다. 염절임 대추의 색상은 온도 10℃, 염농도 10%일때가 좋았으며 온도가 높고 염농도가 이보다 높을 경우는 색상이 불량하였다. Quality changes during salting of dried jujube fruits were investigated. The summarized results were as follows. The changes in the weight of the jujube fruit showed great difference according to the difference of temperature and salt concentration during salting. Softening and decay of tissue appeared when the weight of dried jujube increased over 260-280% during salting. Especially, the phenomena was serious at above 30℃. The most disirable salt concentration and temperature for jujube salting were estimated by color and tissue state, and best condition was 10% and 10℃, respectively. Elution amounts of jujube substance from the fruit to salt solution during salting became high when the salt concentration and temperature were high during salting.

간호실무에서 신봉이론(Espoused theories)에 대한 탐색적 연구

서문자,김혜숙,이은희,박영숙,조경숙,강현숙,임난영,김주현,이소우,조복희,이명하,지성애,하양숙,손영희,권성복,김희진,추진아 성인간호학회 2001 성인간호학회지 Vol.13 No.1

As a nursing practice involves nurses' actions in a specific context of health care, this study has focused on exploring the espoused theories in nursing practice within the action science perspectives, Espoused theories are the belief, principles, and rationale expressed by the practitioner as guiding her/his actions in a situation of practice. The data were analysed qualitatively and 25 elements of espoused theories of nursing action were identified and clustered into 6 categories. The 25 elements of espoused theories are as follows: The clinical nurse worked in wholistic and individual nursing, focussed on the patient's needed, comfort and supportive nursing (5 theories of nursing goal) ; excellent skills, knowledge based, assessment and data collection, explaining, educating or a scientific basis(6 theories of nursing intervention): advocacy, value oriented, treatment, account- ability and commitment(4 theories of nursing ethics) ; human respect. partnership, trust(3 theories of patient-nurse relationship) : knowledgable, accumulated clinical experiences and personally lived experiences. positive perspectives(4 theories of nurse), role of intervention. rewarding peer relationship(3 theories of situations) The above mentioned espoused theories are similar to that of nursing textbooks which students learned through basic nursing education and almost the same as the Acts ofa Nurse in Korean. However, we are doubtful whether nurses actually do as they think. Therefore. it is recommended to review the theories-in-use in order to and any discrepancies between the espoused theories and the reality of nursing actions

간호사의 임상 실무 경험

서문자,손행미,강현숙,권성복,김주현,박영숙,이은희,임난영,조경숙,지성애 성인간호학회 2002 성인간호학회지 Vol.14 No.4

purpose: This study was conducted to describe qualitatively the entities of nurse's experiences in general hospitals and to suggest basic data guiding research on developing Standards of clinical nursing practice in Korea. Method: Fourteen nurses working at general hospitals with over 300 beds in Seoul were interviewed in-depth until saturation using tape-recorders and transcription. Result: The central theme of clinical nursing practice experienced by subjects was "being with clients" that means accepting client's personal character, solving client's needs and providing client-centered nursing. A also "being with clients" was felt to be the responsibility of nurses which was learned from their nursing schools. The nursing strategies performed in order to be with patients were proving skillful nursing techniques, accepting, educating, emotional support, advocating, and self-reflecting, the subjects experienced somewhat problematic affects such as difficulties in interpersonal relationship, work overload, negative image of nursing, deficit of self-confidence for nursing actions, poor working conditions, and unfair treatment. Nurses at the hospital practiced with pride when they felt that they were accepted by clients. Conclusion: Further research is needed to analysis problems in clinical practice and the comparison of nurses' experiences of clinical practice, with nurses' experiences in various settings.

죽음에 관한 주관성 연구

정혜경,김경희,윤은자,류은정,염순교,정연강,권혜진 대한간호학회정신간호학회 1999 정신간호학회지 Vol.8 No.1

The purpose of this study is, by using Q-methodology, to classify the type of attitude for the general public about the death and to understand the specific characters of each type. Q-population was investigated by referring to relevant records and interviewing with the general public and the experts. The final 40 of Q-sample was selected and the data was collected through P-sample, randomly chosen 32 people around Seoul and Kyung-gi area. After analyzing, 4 types were found. Type 1 is aiming for the future life. They believe firmly the future life. They feel certain that eh death means starting for eternal life rather than being afraid of the death or having a despair. Type 2 is valuing reality. They do their best for the reality of life. They take up a positive attitude toward completing their life with responsibilities even at the situation of confronting death have a right to know when they will be dead. They should have enough time to prepare for death. Type 4 is devoting for society. Even though there is only one life, people think that devoting their life for justice is very important. Through the result of this study, people's agreement for nobility and importance of life were found same. It is reconfirmed that instead of being dead suddenly, if it's possible, they want to know the fact of dying to have time to prepare for their death. Also, the fact that everyone has the fear of death is confirmed.

중부지역 옥수수 파종기에 따른 생육단계 및 수량성 변화

서종호, 문중경, 정건호, 서민정, 구자환, 박장환, 배환희, 신성휴, 권영업 忠北大學校 農業科學硏究所 2014 農業科學硏究 Vol.30 No.2

Maize hybrids were planted on April 1, April 25, May 20 and June 15 in 2012, 2013 at the experimental paddy and upland fields in Suwon city , respectively to know changes of growth stage and yield according to different planting time. Maize planting on April 1 was not recommended because total growing days at planting on April 1 was not different with that at planting on April 25 due to many days from planting to emergence over 20 days at planting on April 1. Total growing days were not much different among three planting time after April 25 because days from silking to maturity was lengthened though days from planting to silking was shortened at later planting time. Stalk weight was decreased as planting time was delayed, particularly at planting times after May 20 at paddy field by excess water injury during early growth stage. But, grain yield was not low as in May and June. It is needed to introduce early maturity maize variety as Yanganok at late planting for higher grain yield and enough time for soil preparation for next winter crops

독거노인과 가족동거노인의 신체적 건강상태와 건강행위에 관한 연구

장은희,김후자,권경남,정귀애,김연화,이인혜 영남이공대학 2004 論文集 Vol.33 No.-

Purpose : The purpose of this study was to identify the physical health status and health behavior practice of in-home elderly in order to provide basic data for effective nursing intervention to promote health and quality of life. Method : The subjects for this study were 299 elderly persons in the D city. Data were collected by interview with questionnaires. Result : The ratio of chronic disease was higher for the elderly who live alone than the elderly who live with family. Arthritis was the most common chronic disease of the elderly in spite of the fact that either they live alone or live with family. The physical health status score of the elderly who live with family was statistically higher than the elderly who live alone. The health behavior score of the elderly who live with family was statistically higher than the elderly who live alone. Conclusion : To promote health behavior of the elderly, it is necessary to develop nursing intervention that considers sociocultural tradition and demographic character.

The Linguistic Roots of Korean Traditional Food and Food Ingredients in Hunmong- ja-whae and the Development of Its Application System

Hye Jeong Yang,Kyung Rhan Chung,Hyun Ju Lee,Ahe ryung Yu,Hyun In Oh,HoMoon Seog,Dae Young Kwon,So-ri Lee,Dai-Ja Jang 한국콘텐츠학회 2011 한국콘텐츠학회 ICCC 논문집 Vol.- No.-