Management of the Elderly Patient With Gynecologic Cancer: Report of the 2011 Workshop in Geriatric Gynecologic Oncology

Suh, Dong Hoon,Kang, Sokbom,Lim, Myong Cheol,Lee, Taek Sang,Park, Jeong-Yeol,Kim, Tae-Joong,Kim, Jee Hyun,Lee, Kwang-Beom,Park, Dong Choon,Chung, Hyun Hoon,Kim, Kidong,Seo, Sang-Soo,Kim, Hak Jae,Kim, BMJ 2012 International journal of gynecological cancer Vol.22 No.1

<B>Abstract</B><P>Reflecting the worldwide aging trend and close association of aging with cancer, geriatric oncology is now growing beyond its pioneer years. Nevertheless, geriatric oncology in the gynecologic field is in the beginning stage; indeed, there is no geriatric specialist who is trained in this particular field of gynecologic oncology. Therefore, we held the first workshop in geriatric gynecologic oncology. In this review, we summarize what we discussed at the workshop and provide evidence-based recommendations for the diagnosis and treatment of gynecologic cancer in elderly individuals.</P>

대도시 지역주민의 흡연실태와 관련요인 분석

김기열,임상규,서인선,강창열,이병직,남철현,위광복 慶山大學校 保健福祉硏究所 1997 保健福祉硏究 Vol.1 No.-

To collect basic data for deveoping education program for quitting smoking, 1200 subjects were selected randomly living in Seoul, Pusan, Taegu and suburban areas and interviewed about their smoking habits and attitudes from June 20 to July 20, 1997. The result of this study was summarized as follows: 1. In the general characterisics of subjects, the proportion of female was the higher(53.8%) than that of male. Among them, the portion of twenties was 46.6%. in level of educational background, the rate of college graduates was 45.2%, that of high school was 35.7%, that of middle school was 11.5%. The highest proportion by occupation was 38.9% of student. The next was 11.7% of technician, 10.1% of unemployed, 9.4% of office worker and 9.3% of salesman. 2. The proportion of the smokers among subjects was 34.3%. The portion of male smokers was 65.7%, that of female smokers was 7.3%, which had tendency to increased. At the rate of smoking by age, 47.6% in over fifties, 43.6% in forties and 38.7% in thirties were showed that the rate of smoking was the higher in the older age. 3. In the quantity of smoking cigarettes, the rate of one park of cigarettes per day was 52.7%, that of a half pack was 31.1% and that of over two 53.2% and that in female was 59.1% which was highest. 4. In smoking period, the rate of smokers for over 20 years was 29.7%, that for 1-4 years was 25.1% and that for 5-9 years was 20.9%. The variables of age, marital status, educational level and occupation were statistically significant(p<0.01). 5. In the intention of quitting smoking, 48.0% of subjects wanted to stop smoking, 33.4% of them wanted to reduce amounts of cigarettes and 82.8% fo them had positive intention to stop smoking, on the other side 18.6% of subjects did not have any intention to stop smoking. 6. The proportion of subjects who tried to stop smoking was 67.9%. By characteristics, the rate of 67.9% in male, 27.3% in female, 90.9% in under nineteens, 73.6% in married group 69.4% in lower social class, 77.8% in high school graduated and 72.3% in Buddist was the higher than that of other groups. 7. The proportion of subjects who succeeded in quitting smoking was 12.0%. By characteristics, the rate of 40.2% in male, 34.8% in over 50 years old, 19.7% in married group, 15.4% in lower social class, 13.9% in apartment resident, 15.7% in high school graduate and 17.1% in Buddist was the higher than that of other group. 8. In the reason of quitting smoking, 81.0% of subjects had quitted smoking for health, 6.0% of them for religion and 13.0% of them for others. By characteristics, the rate of reason for health was 83.5% in male, 100.0% in age of forties, 84.6% in lower social class. 9. In the affecting factors of quitting smoking, 40.7% of subjects was influenced on family which was the highest, 29.6% of them on health education, 14.8% of them on friend's recommandation, 9.9% of them on medical doctor's advice and 4.9% of them on campaign. By age, twenties was affected by friend, thirties by health education and forties by family. 10. The most affecting independent variable of smoking was sexuality (β=0.42055), age(β=0.25285), drinking (β=0.15425), marital status and health condition(R²=44.8%). These results were shown that education program for quitting smoking especially emphasized injurious to health should be continued in the unit of family, school, office and society, particularly education program for female should be strengthened.

Parametric Study on the Motion of a Spring Mimicking a Flagellum

Won Yeol Choi,Yong Kweon Suh,Sangmo Kang 한국전산유체공학회 2014 한국전산유체공학회 학술대회논문집 Vol.2014 No.10

We perform parametric study on the motion of a spring-type flagellum in a viscous fluid with various parameters including the effect of wall. We conduct simulations by using a commercial software package, CFX v13, ANSYS Inc., and in order to validate the simulation, we compare our numerical results with data obtained with other methods given by utilizing an open code in Matlab provided in the literature. The simulations are performed for the range of the spring pitch λ, the helical radius R, the rotational angular speed of the spring ω, the fluid viscosity μ and the proximity of the spring to the surrounding wall. We confirm that our numerical results agree well with those given by the slender body theory (SBT). We also present the relationship between thrust and parameters (λ, R, ω, μ and proximity to the wall). We can see that the thrust is directly proportional to rotational velocity of flagellum and viscosity of fluid and that the thrust is increased with the helical radius. Interestingly, the thrust rapidly increases with the spring pitch up to λ=77mm, beyond which it slowly decreases, implying that the thrust is maximized at λ=77mm under a specific parameter set selected in this study.

Serial Changes of Heat Shock Protein 70 and Interleukin-8 in Burn Blister Fluid

( Kicheol Yoo ),( Kang Yeol Suh ),( Gi Hun Choi ),( In-suk Kwak ),( Dong Kook Seo ),( Dohern Kym ),( Hyeon Yoon ),( Yong Se Cho ),( Hye One Kim ) 대한피부과학회 2017 Annals of Dermatology Vol.29 No.2

Background: It has been reported that heat shock protein 70 (HSP70) and interleukin-8 (IL-8) play an important role in cells during the wound healing process. However, there has been no report on the effect of HSP70 and IL-8 on the blisters of burn patients. Objective: This study aimed to evaluate the serial quantitative changes of HSP70 and IL-8 in burn blisters. Methods: Twenty-five burn patients were included, for a total of 36 cases: twenty cases on the first day, six cases on the sec-ond, five cases on the third, three cases on the fourth, and two cases on the fifth. A correlation analysis was performed to de-termine the relationship between the concentration of HSP70 and IL-8 and the length of the treatment period. Results: The HSP70 concentration was the highest on the first day, after which it decreased down to near zero. Most HSP70 was generated during the first 12 hours after the burn accident. There was no correlation between the concen-tration of HSP70 on the first day and the length of the treat-ment period. No measurable concentration of IL-8 was de-tected before 5 hours, but the concentration started to in-crease after 11 hours. The peak value was measured on the fourth day. Conclusion: While HSP70 increased in the first few hours and decreased afterwards, IL-8 was produced after 11 hours and increased afterward in burn blister fluid. These findings provide new evidence on serial changes of in-flammatory mediators in burn blister fluid. (Ann Dermatol 29(2) 194∼199, 2017)

점성유체 중에 회전하는 스프링의 추진적 거동에 관한 수치해석 모델

최원열(Won Yeol Choi),서용권(Yong Kweon Suh),강상모(Sangmo Kang) 대한기계학회 2015 大韓機械學會論文集B Vol.39 No.6

본 논문에서는 박테리아 편모를 모사한 스프링 모델을 이용하여 박테리아의 편모의 추진적 거동에 관한 연구를 수행하였다. 본 해석에서는 상용프로그램을 사용하였으며, 별도의 회전영역 설정에 따른 수치기법의 타당성 확인과 더불어 파라미터 연구를 수행하였다. 수치해석 결과는 전반적으로 Resistive force theory와는 잘 일치하지 않았지만, Slender body theory와는 잘 일치하였다. 그리고 스프링의 회전속도, 피치, 나선반경 및 유체의 점성의 영향을 확인하였다. 또한 벽과의 거리에 따른 효과도 분석하였다. In this paper, we study the propulsive behavior related to the flagellar motion of bacteria using a spring model. A commercial program was used to conduct simulations, and we verified the numerical technique by setting an additional rotating domain and conducting a parametric study. The numerical results are in good agreement with slender-body theory, although overall, they are not in agreement with resistive-force theory. We confirm the effect of the rotational velocity, pitch, helical radius, fluid viscosity, and, in particular, the distance from the wall on the propulsion of the spring.

Preparation of pH sensitive Polyurethane Gels and Their Swelling behavior Ⅱ : Effect of pendant and termnal ionic groups

박강열,김주영,서경도 ( Kang Yeol Park,Ju Young Kim,Kyung Do Suh ) 한국공업화학회 1996 한국공업화학회 연구논문 초록집 Vol.1994 No.1

Cell openness manipulation of low density polyurethane foam for efficient sound absorption

Hyuk Park, Ju,Suh Minn, Kyung,Rae Lee, Hyeong,Hyun Yang, Sei,Bin Yu, Cheng,Yeol Pak, Seong,Sung Oh, Chi,Seok Song, Young,June Kang, Yeon,Ryoun Youn, Jae Elsevier 2017 Journal of sound and vibration Vol.406 No.-

<P><B>Abstract</B></P> <P>Satisfactory sound absorption using a low mass density foam is an intriguing desire for achieving high fuel efficiency of vehicles. This issue has been dealt with a microcellular geometry manipulation. In this study, we demonstrate the relationship between cell openness of polyurethane (PU) foam and sound absorption behaviors, both theoretically and experimentally. The objective of this work is to mitigate a threshold of mass density by rendering a sound absorber which shows a satisfactory performance. The cell openness, which causes the best sound absorption performance in all cases considered, was estimated as 15% by numerical simulation. Cell openness of PU foam was experimentally manipulated into desired ranges by adjusting rheological properties in a foaming reaction. Microcellular structures of the fabricated PU foams were observed and sound absorption coefficients were measured using a B&K impedance tube. The fabricated PU foam with the best cell openness showed better sound absorption performance than the foam with double mass density. We envisage that this study can help the manufacture of low mass density sound absorbing foams more efficiently and economically.</P>

만성 바이러스 간염 환자에서 간조직 내 아연의 농도

이재승,강대환,문지현,송근암,조몽,양응석,주형준,서경덕,김정렬 대한간학회 2001 Clinical and Molecular Hepatology(대한간학회지) Vol.7 No.2

Background and Aims - Zinc is an essential, mostly intracellular, trace element which participates in many oxidative or deoxidative reactions and in a protective action on liver cell activity. Plasma zinc levels are known to decrease in patients with liver disease including chronic viral hepatitis. The aim of this study was to reveal whether hepatic zinc concentrations have a correlation with grades of necroinflammation or stages of fibrosis in the patients with chronic viral hepatitis. Methods - This study consisted of 50 subjects (43 chronic hepatitis B, 4 chronic hapatitis C, and 3 cirrhosis). Each specimen of liver tissue was classified with the grade of lobular inflammation, portal/periportal inflammation, and stage of fibrosis according to Scheuer`s method. Hepatic zinc concentration was determined by ICP-Atomic Emission Spectrometry. Results: The mean hepatic zinc concentration in the 50 chronic viral hepatitis patients was 233.66㎍/g dry weight of liver tissue. The hepatic zinc levels were significanty correlated with the grades of portal/periportal inflammation (rs=-0.385, p=0.006), and grades of lobular inflammation(rs=-0.342, p=0.015). The stages of fibrosis were also negatively related (rs=-0.423, p=0.002). The zinc concentrations differed significantly among grades of lobular inflammation (p=0.013) and among stages of fibrosis (p=0.044). Conclusions- Hepatic zinc concentrations showed negative correlation with grades of portal/periportal inflammation, lobular inflammation, and stage of fibrosis in the patients of chronic viral hepatitis. These results suggest that decreased hepatic zinc concentration might be associated with severe hepatic injury and reflect decreased protective activity on liver cell injury.(Korean J Hepatol 2001;7:147-152)

위내시경(胃內視鏡)으로 진단된 단발성(單發性) 양성위궤양(良性胃潰瘍)과 다발성 양성위궤양(良性胃潰瘍)의 비교관찰

장동익,강진경,박인서,최흥재,백종열 대한소화기학회 1976 대한소화기학회지 Vol.8 No.2

The clinical phenomenon of multiple benign gastric ulcer (MBGU) has been the subject of' a number of investigations documenting its incidence and clinical features but the clinical significance of MBGU is relatively unknown. There was no report about the MBGU in this country. The purpose of this study is to evaluate the clinical and the gastrofiberscopic findings of a group of patients with MBGU and to compare them with those of patients wit I single beqign gastric ulcer (SBGU) who were encountered during the sarne interval of time.. During the 4 years and 8 months from Jan. 1971 to Aug. 197v, 338 patients were documented as having benign gastric ulcer based on gastrofiberscopy and the stomach mucosal biopsy under the direct vision at Yonsei Medical Center. The following results were obtained. 1) 227 patients (81.5%) demonstrated SBGU and 61 patients (18.5%) MBGU. The sex ratio of SBGU was 7.7: 1 and MBGU 4.5: 1. 2) 1 he peak incidence of age was 6th decade in SBGU but 4th decade in MBGU. 3) The most common clinical symptoms of the patients was epigastric and upper abdominal pain in both group. The next common one was indigestion in SMGU but nausea or vomiting in MBGU. 4) The duration of clinical symptom was 1/2-1 year (50.2%) in SBGU and below 1/2 year (63.9%) in MBGU. 5) The most frequent site of ulcer was the lesser curvature of the angle and lower body of the stomach in both group. The ulcer in SBGU was large and deep, and in MBGU smal.l and shallow. 6) 48.4% of patients was accurately diagnosed by UGI series in SBGU and only 14.8% in MBGU.

스티렌-옥사졸린 공중합체를 통한 고밀도 폴리에틸렌/폴리스티렌-점토 나노복합체의 블렌드

한권형,박강열,서경도,박종헌 한국공업화학회 2002 응용화학 Vol.6 No.2

To improve the compatibility of high density polyethylene (HDPE)/polystyrene (PS), we carried out grafting of maleic anhydride (MAH) onto HDPE in a xylene solution using a radical initiator. By the FT-IR, we confirmed the introduction of MAH onto HDPE. We also prepared poly(styrene-co-oxazoline) (PO)/clay (montmorillonite-15A) nanocomposites with intercalation structures, and their intercalation structure was confirmed by the X-ray diffraction spectroscopy (XRD). By using MAH functionalized HDPE and PO/clay nanocomposites with intercalation structure as compatibilizers simultaneously, we blended the immiscible HDPE/PS and observed the compatibilizing effect in view of the contents of clay. From the result of these experiments, we could observe that the addition of clay gave rise to the increase of viscosity and the decrease of droplet, as compared with using no compatibilizers in HDPE/PS blends. This was believed that MAH reacted with oxazoline at the interface. and clay is situated in that.