구절산과 인근산지(충남)의 식물상 : Chungcheongnam-do

이웅빈,전유미 용인대학교 자연과학연구소 2004 自然科學硏究所論文誌 Vol.8 No.2

The flora of Mt. Gujeolsan (329m) and neighbor areas such as Mt. Noseongsan (348m) was surveyed in this study from the middle of February till the middle of October, 2001. The vascular plants collected from these areas are as following: 123 taxa those are 16 varieties, 107 species, 92 genera, 48 families, 24 orders and 5 phyla. There are 4 taxa from southern plant in these areas. And there are two taxa of special protected plants which was designated from Ministry Environment of Korea, those are one taxon 3rd, and one taxon of 1st grade.

Spheroid 조합자극치료 적용이 신체구성에 미치는 영향

홍성찬,김영빈,정동혁,박병근,김유성,이성진 원광대학교 체력과학연구소 2008 體力科學硏究 Vol.30 No.1

The present study aims to explore the effects of applying spheroid-combined stimulating therapy on body composition. For this aim. 20 persons were selected as subjects and 10 of them each were assigned to the experimental group and control group, respectively. The experimental group was applied a 12-week combined stimulating therapy and changes in physical constitution of the members were measured before application and 4, 8 and 12 weeks after application. From the study, following conclusions could be drawn: First, body weights of the experimental group decreased from 59.9kgs before application of the spheroid-combined stimulating therapy to 57.2kgs 12 weeks after application, no significant but 4.51% change. Second, body fats of the experimental group changed from 18.8kgs before application to 16.4kgs 12 weeks after application, no significant but 12.77% reduction. Third, % fats of the experimental group decreased from 31.2% before application to 28.6% 12 weeks after application, no significant change but 8.33% reduction. Fourth, body mass index(BMI) of the experimental group decreased from 23.23 kg/㎡ before application of the therapy to 21.43kg/㎡ after application, no significant but 8.03% reduction. As seen above, the 12-week application of the spheroid-combined stimulating therapy produced no significant changes in physical constitution as physical exercise did, but improved physical constitution by reducing certain amount of boy weight, body fat, % fat and BMI. In order to detect more positive and significant changes in physical constitutions, continued studies and clinical experiments should be performed to more diverse subjects using technically reinforced equipment for spheroid-combined stimulating therapy.

다큐멘터리 재현양식 연구 : <워낭소리>와 <택시 블루스>를 중심으로

민환기,이유빈 영상예술학회 2009 영상예술연구 Vol.15 No.-

다큐멘터리가 묘사하고자하는 사람이나 사건은 현실에 실제로 존재한다. 픽션 영화의 인물이나 장소가 허구의, 만들어진 존재임에 반하여 다큐멘터리가 묘사하는 대상은 다큐멘터리의 묘사와는 상관없이, 또는 다큐멘터리가 그 존재를 묘사하지 않았을 때에도 존재한다. 하지만 현실에 존재하는 대상을 재현하기 위해서는 인공적인 장치에 의존해야 한다. 그 장치는 재현해야 하는 현실의 속성과는 다른 종류의 미학적인 장치이다. 그렇기 때문에 미학적인 장치를 통한 재현은 현실을 지시하면서도 왜곡하거나 변화시킬 가능성을 처음부터 안고 출발한다. 본 글은 <택시 블루스>와 <워낭소리>의 재현양식의 분석을 목표로 한다. 두 영화 모두 혼합된 다큐멘터리 양식을 사용하면서 다큐멘터리가 가진 표현양식의 한계를 넘어서려고 시도했다. 그 결과로 <택시 블루스>는 픽션이냐 아니냐 하는 논란에 휩싸였고 <워낭소리>는 다큐멘터리로서는 드물게 300만 관객을 동원하는 대중적 성공을 거두었다. 물론 재현양식이 그 결과를 모두 설명할 수 있는 것은 아니겠지만 두 영화가 가지고 있는 장점과 단점은 많은 부분 특정한 재현양식의 차용과 그것의 변형에서 비롯된다. 빌 니콜스(Bill Nichols)의 재현양식의 구분을 따라서, 두 영화가 차용한 지배적인 재현양식과 그것의 변형이 어떤 목적을 위해서 어떻게 사용되었고 그것의 효과가 무엇인지를 그리고 그러한 재현양식이 현실과 맺는 관계를 분석한다. A documentary film describes people or events being in the world. People or events in the documentary have existed without such a description unlike people or events in the fiction film. To represent things in the world depends on artificial devices different from things in their nature. Because of it, things described are always both an indication and a distortion of things in the world. I try to analyse Taxi Blues and An old partner in terms of representational mode. Both films try to negotiate confliction between the real and its representation with mixed representational mode. it produced a huge success of An old partner in box office and critical debates on Taxi Blues. Although it is not sufficient to explain all the issues related to both films by analysis of their representational mode, I believe it can hint its success and failure of each film regarding such a negotiation and enrich discourses on documentary film-making in Korean soil. With Bill nichols's categorization, I will analyse both films' representational mode, and its effect on the real and its representation, and the audience.

입원된 정신활성물질 남용자의 사회정신의학적 특징

이혁,김유광,김경빈 大韓神經精神醫學會 1991 신경정신의학 Vol.30 No.1

This study was attempted to clarify sociopsychiatric characteristics according to the class of psychoactive substances which were classified into 8 groups such and methamphetamin, cocaine, inhalants(bond/gas), dextromethorphan(Romilar), sedatives marijuana, analgesics and etc. The data of the study were collected from 134 psychoactive substance abusers(89men, 45women), who had admitted to SNMH during past 5 years. The results were as follows ; 1) The mean age of patients was 26.5±9.6 years and according to the class of psychoactive substance, inhalant and dextromethorphan abusers were significantly younger than sedatives and analgesics abusers(P〈0.01). 2) 43.1% of patients were grown up in broken family until puberty and 27.9% of married patients showed unstable marital state such as a divorce or seperation. 3) 41.4% of patients had past history of delinquent behavior and especially, inhalants and dextromethorphan abusers had more past history of delinquent behavior than sedatives and analgesics abusers(P〈0.01). 4) The main motive of mitiation of psychoactive substance was peer pressure, relief of psysical symptoms, curiosity in that order. 75% of inhalants abusers were itiated by peer pressure, but most of sedatives and analygesics abusers used it for the purpose of relieving of physical symptoms, and methamphetamine abusers used it mainly due to peer pressure or for the purpose of increasing sexual plesure(P〈0.01). 5) 57.5% of patients reported the experience of unwanted response such as unpleasant hallucinatory state, loss of control, and psychotic state after use of psychoactive substances. Especially the unwanted respose was reported more frequently in methamphetamin and inhalants abusers. 6) 38.5% of patients abused more than two classes of psychoactive substances, and their significant combination types were not found but inhalant-dextromethorphan, analygesics-sedatives and methamphetamine-marijuana combination types were relatively common.

Autophagy inhibition by cudraxanthone D regulates epithelial-mesenchymal transition in SCC25 cells

Yu, Su-Bin,Bang, Tae-Hyun,Kang, Hae-Mi,Park, Bong-Soo,Kim, In-Ryoung 대한구강생물학회 2021 International Journal of Oral Biology Vol.46 No.1

Cudraxanthone D (CD) is a natural xanthone compound derived from the root barks of Cudrania tricuspidata. However, the biological functions of CD in human metabolism have been rarely reported until now. Autophagy is the self-degradation process related to cancer cell metastasis. Here, we elucidated the effects of CD on human oral squamous cell carcinoma (OSCC) cells' metastatic ability. We confirmed that CD effectively decreased the proliferation and viability of SCC25 human OSCC cells in time- and dose-dependent manners. Also, the metastasis phenotype of the SCC25 cell (migration, invasion, and epithelial-mesenchymal transition [EMT]) was inhibited by CD. To further investigate the mechanism by which CD inhibited the metastatic capacity, we detected the relationship between EMT and autophagy in the SCC25 cells. The results revealed that CD inhibited the metastasis of the SCC25 cells by attenuating autophagy. Thus, our findings produced a potential novel agent for the treatment of human OSCC metastasis.

First Report on Bacterial Heart Rot of Garlic Caused by Pseudomonas fluorescens in China

Bin Li,Rong Rong Yu,Shan Hong Yu,Wen Qiu,Yuan Fang,Guan Lin Xie 한국식물병리학회 2009 Plant Pathology Journal Vol.25 No.1

An unreported disease of garlic was observed in commercial fields in Jiangsu province, China. The symptoms started as water soaked lesions at the base of the leaves. Later, water-soaked areas developed on stems and spread to the internal tissues, followed by yellowing and necrosis along leaf edges and soft rot of the stems. The causal organism isolated from symptomatic plants was identified as Pseudomonas fluorescens based on its biochemical and physiological characteristics and confirmed by the cellular fatty acid composition and Biolog data as well as 16S rRNA gene sequence analysis. The bacterial isolates caused similar symptoms when inoculated onto garlic plants. In addition, leek and shallot were susceptible to the P. fluorescens pathogen. However, the P. fluorescens pathogen failed to cause any symptoms when it was inoculated onto 15 other plants. This is the first report of a bacterial disease of garlic caused by P. fluorescens in China.

miR-638 Serves as a Biomarker of 5-Fluorouracil Sensitivity to Neoadjuvant Chemotherapy in Breast Cancer

Bin Wang,Kun Wang,Jian Yu,Xiao-meng Hao,Yu-lu Liu,Ai-Yan Xing 한국유방암학회 2022 Journal of breast cancer Vol.25 No.3

Purpose: Neoadjuvant chemotherapy (NAC) is widely used to treat breast cancer (BC). The prediction and evaluation of chemotherapy responses remains a significant challenge. Methods: MicroRNAs (miRNAs) play a crucial role in cancer drug resistance. We used a miRNA microarray and identified that miR-638 is downregulated in chemoresistant cases. However, the exact role of miR-638 and the underlying mechanisms of chemoresistance remain unclear. Using real-time quantitative reverse transcription polymerase chain reaction, we found significant downregulation of miR-638 in chemoresistant patients compared with chemosensitive patients. To explore the function of miR-638, we overexpressed and inhibited miR-638 expression in MDA-MB-231 and MCF-7 cells by transfecting them with miR-638 mimics and miR-638 inhibitor, respectively. Cell proliferation and apoptosis were measured using MTS and flow cytometry, respectively. A minimal patient-derived xenograft (MiniPDX™) model was established to evaluate the chemosensitivity to different drugs. Results: The results showed that cell proliferation decreased and cell apoptosis increased in cells transfected with the miR-638 mimic, and cell proliferation and apoptosis were reversed with transfection of miR-638 inhibitor compared with the control group. Among patients who received 5-fluorouracil (5-FU), miR-638 expression levels were lower in the chemoresistant group than in the chemosensitive group. The MiniPDX™ model showed that MDA-MB-231 cells overexpressing miR-638 were more susceptible to 5-FU treatment in vivo. Conclusion: We provided evidence of acquired resistance to 5-FU caused by miR-638 deficiency. Alterations in miR-638 may be used with 5-FU chemotherapy during NAC for BC.

Fecal Calprotectin Levels Significantly Correlate with Polyp Size in Children and Adolescents with Juvenile Colorectal Polyps

Yu Bin Kim,Ju Young Kim,Sujin Choi,Yoo Min Lee,So Yoon Choi,Soon Chul Kim,Hyo-Jeong Jang,Yoon Lee,In Sook Jeong,Dae Yong Yi,Yunkoo Kang,Kyung Jae Lee,Byung-Ho Choe,Ben Kang 대한소아소화기영양학회 2023 Pediatric gastroenterology, hepatology & nutrition Vol.26 No.1

Purpose: We aimed to investigate factors that correlate with fecal calprotectin (FC) levels in children and adolescents with colorectal polyps. Methods: Pediatric patients aged <19 years who underwent colonoscopic polypectomy for a juvenile polyps (JPs) and FC tests were simultaneously conducted in a multicenter, retrospective study. Baseline demographics, colonoscopic and histological findings, and laboratory tests, including FC levels, were investigated. Correlations between the factors were investigated, and linear regression analysis revealed factors that correlated with FC levels. FC levels measured after polypectomies were investigated and the FC levels pre- and post-polypectomies were compared. Results: A total of 33 patients were included in the study. According to Pearson correlation analysis, the polyp size was the only factor that showed a statistically significant correlation with FC levels (r=0.75, p<0.001). Furthermore, according to the multivariate linear regression analysis, polyp size was the only factor that showed a statistically significant correlation with FC levels (adjusted R2=0.5718, β=73.62, p<0.001). The median FC level was 400 mg/ kg (interquartile range [IQR], 141.6–1,000 mg/kg), and the median polyp size was 14 mm (IQR, 9–20 mm). Nineteen patients underwent post-polypectomy FC tests. FC levels showed a significant decrease after polypectomy from a median of 445.2 mg/kg (IQR, 225–1,000) to 26.5 mg/kg (11.5–51) (p<0.001). Conclusion: FC levels significantly correlated with polyp size in children and adolescents with JPs.

레이더 흡수특성이 있는 저적외선 방출 복합섬유의 제조 및 특성 연구

Bin Yu,Lu Qi 한국고분자학회 2006 폴리머 Vol.30 No.2

Study on Multi Objective Optimization Method and It Application in Aviation and Deceleration Device

Yu Guang-bin,Song Ye,Duan Yuan-wang,Zhao Xing-fu,Qu Zhigang,Sun Yong-guo 보안공학연구지원센터 2016 International Journal of Smart Home Vol.10 No.5