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비만 개선 효과를 지닌 탄수화물 및 지방 흡수 억제 기능성 식이조성물 개발
윤유식,최선미,홍순복,홍정미,김정원,이홍석,홍성길 한국조리과학회 2002 한국식품조리과학회지 Vol.18 No.3
In a previous study, we developed a new food additive as an egg yolk antibody (IgY) against carbohydrate digestion enzymes for the regulation of blood glucose level and weight control. The IgY delayed and decreased the increment of blood glucose level after administration of sucrose in human being by 30% in 20∼30 min. We also developed a lipase inhibitor as a water extract of two kinds of herb, Platycodon grandiflorum and Solanum melongena. Twenty three volunteers were subjected to the intake of the egg yolk IgY plus the herbal extracts for 50 days. In average, the treated subjects appeared to lose 1.96 ㎏ of body weight and 3.4 ㎏ of body fat mass during the treated period. Furthermore, Panniculus adiposus and breech size were significantly decreased during the experimental period. Above results suggested that the administration of the dietary additives composed of egg yolk IgY and natural herbal extract improve the obesity by the decrement of body weight and body fat mass.
반응표면 분석을 이용한 Salmonella enteritidis의 증식 효능 평가
홍정미,정효준,이홍근 한국환경과학회 2002 한국환경과학회지 Vol.11 No.12
This stidy was performed to investigate the single and combined effect of concentrations of garlic juice according to the pH and temperature on the growth of Salmonella enteritdis in brain heart infusion broth, and to develope Response surface model for the effect of concentrations of garlic extract. The results of electric conductibility of Salmonella enteritidis growing in the range of incubation temperature (25~42℃), PH(5.5~9.0) and concentration of garlic juice(0~0.8%) showed that a badge with high low D.T.value and concentration of garlic extract were significantly with D.T.value and concentration of garlic extract were significantly correlated with D.T.value (p<0.01). Growth of Salmonella enteritidis in the condition of 37℃ and pH7.0 presented the lowest D.T.value.
탱고 backward walk 동작시 신발 굽 유형에 따른 하지의 근전도 분석
정미라,서국웅,강영택,염창홍 한국운동역학회 2002 한국운동역학회지 Vol.12 No.1
The purpose of this research is to provide scientific training guides and the basis for preventing injuries in performing tango backward walk by comparing the effects the height and shape of a heel will have on leg muscles and determining the difference between skilled and unskilled dancers through EMG analysis according to different types of shoes Total eight female athletes were selected for this research. Four with six years of professional dancing experience and another four with one year of dance sports experience. Utilizing the EMG system, rectus femoris, biceps femoris, anterior tibialis, gastrocnemius were measured under different heights (0cm, 5cm, 7cm, 9cm) and shapes (flat, fine, wide) of a heel. Experiments were conducted calculating EMG peak value and muscle load ration under different types of shoes in order to analyze the EMG of leg muscles and Erector Spinae when performing tango backward walk. The result was as follows: 1. The EMG peak value of leg muscles showed significant difference under different heights of a heel in anterior tibialis(p<.001) and gastrocnemius(p.<01) in case of skilled dancers, and in biceps femoris(p.<01) in case of unskilled dancers. 2. The EMG peak value of leg muscles showed significant difference under different shapes of a heel in anterior tibialis(p<.001) and gastrocnemius(p<.001) in case of skilled dancers, and showed no significant difference in case of unskilled dancers. 3. The muscle load ration of leg muscles showed different degrees of muscle contribution between skilled and unskilled dancers. The muscle load ration was in the order of anterior tibialis, rectus femoris, biceps femoris, and gastrocnemius in case of skilled dancers and anterior tibialis, gastrocnemius, biceps femoris, and rectus femoris in case of unskilled dancers.
경막 내 colistimethate 투여로 치료한 다제 내성 cinetobacter baumannii 뇌실염
홍유아,유진홍,김진진,모은영,안건희,정희경,김진석,이현정,정미향,윤승배 대한감염학회 2009 감염과 화학요법 Vol.41 No.4
Acinetobacter species is a non-fermentative aerobic gram-negative coccobacillus that is an important pathogen found in nosocomial infections. Recently, multi-drug resistant Acinetobacter baumannii (MDR-AB) infections have been increasing and pose a serious problem. Most such infections present as bacteremia, pneumonia, or a wound infection; however, CNS infections are very rare. We herein present a case of ventriculitis caused by MDR-AB in a 37-year old man after a neurosurgical intervention. The patient was successfully treated with intrathecal colistimethate.
Duchenne형 進行性 筋異養症 保因者 檢出에 Restriction Fragment Length Polymorphism 이용에 관한 硏究
李美正,朴吉洪,朴善華,柳總根 고려대학교 의과대학 1991 고려대 의대 잡지 Vol.28 No.3
We performed genetic analysis for detection of carrier state of Duchenne's muscular dystrophy (DMD). As genetic markers of the disorder, We used DNA-sequence polymorphisms detected with 6 different DNA probes derived from the vicinity of the DMD locus at genetic distance less than 15 cmo or from within the gene. on the short arm of X chromosome. In the family we studied. a consultand was a 29 years old woman whose maternal grandfather was a DMD patient who was unavailable. Therefore, all of her maternal aunts were DMD carriers whose next generations were requested for DNA studies. On the basis of linkage analysis. a proband and her niece were deemed to be unaffected with an accuracy of more than 99%, and we anticipated another two femals and one malt to be unaffected with 98% probability (normal serum creatine kinase level) where crossover events between intragenic(pERT 87.30) and flanking probes(pXUT23) were detected. but carrire risk of a female with the same haplotype was elevated to 41% taking account of an increased serum creatine kinase level. Two other females were predicted to be affected with 99.9 and 97.1% probabilities each. However. a genetic interpretation was impossible for one male in which a crossover breakpoint could not be determinied because of his mother's homozygosity of the alleles between crossovered alleles where hitherto pessibility of intragenic crossover could not be ruled out Our experience suggests that genetic diagnosis based on recombinant deoxyribonucleic acid techniques are assuming increasing importance. and provide a highly accurate method for carrier detection and prenatal diagnosis of DMD. By the way, despite the large number of intragenic and flanking DNA polymorhpisms available, uncertainties often remain in the genetic diagnosis of DMD. Pitfalls are presented by the large size of the region in which Duchenne's mutations can occur. Crossover events in this region. especially intragenic ones, which result in an exchange of DNA between two X chromosomes, can,rener DNA-marker studies inaccurate.
임미경,정희일,오세홍 원광대학교 생체재료·매식연구소 1995 원광생체재료·매식 Vol.4 No.1
Balance between antibacterial effectiveness and biocompatibility is important property of root canal irrigation solutions. The aim of this study was to evaluate the cytotoxic effect of irrigation solutions on cultured L929 cells. Seven irrigation solutions and thier serial dilution solution were applied to L929 cells. Radiochromium release of damaged L929 cells after five-minute, thirty-minute and four-hours exposure to each irrigation solutions were monitored using gamma particle counter. L929 cells which were exposed to 1:1 and 1:10 diluted solutions of sodium hypochlorite and cresol for five and thirty minutes showed cytotoxic change. Povidone had cytotoxic effect on L929 cells after five minutes, thirty minutes and four hours. Normal saline, alcohol, Wydex and hydrogen peroxide showed weak cytotoxic effect on L929 cells.