일측성 연수 경색에 의한 수의성 및 자동 호흡 부전 1예

송인욱,제종석,이보람,이태경,안무영,박형국 대한신경과학회 2000 대한신경과학회지 Vol.18 No.2

도파민 치료로 호전된 파킨슨병 환자의 Pisa증후군

송인욱,임성철,김중석,이상봉,류선영,김영인,이광수 대한신경과학회 2008 대한신경과학회지 Vol.26 No.4

지주막하 출혈로 발생한 일과성 완전 기억상실증

송인욱,김중석,이광수,정성우 대한노인병학회 2009 Annals of geriatric medicine and research Vol.13 No.3

The etiology and pathogenesis of transient global amnesia (TGA) is still unclear. Several mechanisms have been proposed, including arterial thromboembolic ischemic attacks, epilepsy, and migraine. However, TGA following severe headache has not been reported, to our knowledge. We described a patient presenting with TGA associated with the sudden onset of headache provoked by a subarachnoid hemorrhage. MRI and CT with angiography of the brain showed no abnormal findings. CSF study revealed hemorrhage. Single photon emission computed tomography revealed mild low perfusion at both hippocampal regions. 일과성 완전 기억상실의 원인과 기전은 아직까지 명확하지 않은 상태이다. 최근에 동맥혈전에 의한 허혈성 병변, 간질 그리고 편두통 기전에 의해 발생된다고 제시되고 있다. 하지만 심한 두통으로 인한 일과성 완전 기억상실은 아직까지 보고되고 있지 않다. 본 저자들은 지주막하 출혈로 인한 심한 두통으로 발생된 일과성 완전 기억상실을 보인 환자를 경험하여 문헌 고찰과 함께 보고하고자 한다. 본 환자에서 시행된 뇌자기공명영상과 컴퓨터단층뇌혈관조영술에서 정상소견을 보였으나, 뇌척수액 검사상에서 뇌출혈 소견을 보였고, 뇌단일광자방출단층촬영술(brainsingle photon emission computed tomography)에서는 양측 해마영역에서 관류가 저하된 소견을 보였다.

Can virtual mock crime replace actual mock crime? An event-related potential study

송인욱,김혜민,이경은,장은희,김현택 한국법심리학회 2019 한국심리학회지: 법 Vol.10 No.2

For detecting deception research, the Concealed Information Test (CIT) is the most widely used method in conjunction with electroencephalography (EEG). Moreover, mock crime scenarios were commonly adopted for providing materials for lying. Mock crime scenarios have relatively higher ecological validity than other paradigms like autobiographical information or card test. However, current mock crime scenarios also have some limitations because of ethical issues, resource issues, and experimental controllability. Virtual reality (VR) is a potential alternative to overcome the disadvantages. Nonetheless, few studies used VR for mock crime, and there is no research on the comparison between ‘actual’ mock crime and ‘virtual’ mock crime. In the present study, we developed a high-fidelity virtual environment and used it for the virtual mock crime. Participants were randomly assigned both for the Crime status (innocent or guilty) and the Environment mode (actual or VR). After the scenarios, participants were tested by P300-based CIT with EEG recording. To verify the effects of virtual mock crime on subsequent EEG data during CIT, we focused on the P300 event-related component (ERP) and individual classification using the bootstrapping method in the study. As we hypothesized, the main effect of environment mode was not significantly different, and the interaction between stimuli type (target, probe, irrelevant) and environment mode was also not significant when we exclude one outlier. Furthermore, the accuracy of individual classification was equivalent between the actual and the VR. These results were also supported by ROC analysis and equivalence test. All statistical results suggest that there is no significant difference between actual mock crime and virtual mock crime. In conclusion, the study suggests that the virtual mock crime is a potential alternative method for mock crime scenarios.

Differences in Regional Glucose Metabolism of the Brain Measured with F-18-FDG-PET in Patients with Essential Tremor According to Their Response to Beta-Blockers

송인욱,하상원,양영순,정용안 대한영상의학회 2015 Korean Journal of Radiology Vol.16 No.5

In this study, there was an investigation as to whether there is a functional difference in essential tremor (ET), according to responses to beta-blockers, by evaluating regional changes in cerebral glucose metabolism. Seventeen male patients with ET were recruited and categorized into two groups: 8 that responded to medical therapy (group A); and 9 that did not respond to medical therapy (group B). Eleven age-sex matched healthy control male subjects were also included in this study. All subjects underwent F-18 fluorodeoxyglucose (FDG)-PET, and evaluated for their severity of tremor symptoms, which were measured as a score on the Fahn-Tolosa-Marin tremor rating scale (FTM). The FDG-PET images were analyzed using a statistical parametric mapping program. The mean FTM score 6 months after the initiation of propranolol therapy was significantly lower in group A (18.13 > 8.13), compared with group B (14.67 = 14.67). The glucose metabolism in group A in the left basal ganglia was seen to be decreased, compared with group B. The ET showed a more significantly decreased glucose metabolism in both the fronto-temporo-occipital lobes, precuneus of right parietal lobe, and both cerebellums compared with the healthy controls. Essential tremor is caused by electrophysiological disturbances within the cortical-cerebellar networks and degenerative process of the cerebellum. Furthermore, ET may have different pathophysiologies in terms of the origin of disease according to the response to first-line therapy.

Determining factors of Pro-BNP level in patients with lone atrial fibrillation (초)

송인욱,신동구,조정환,강상욱,이원재,홍그루,박종선,김영조,심봉섭 대한내과학회 2008 대한내과학회 추계학술대회 Vol.2008 No.-

A Case of Huge Thrombus in the Aortic Arch with Cerebrovascular Embolization

송인욱,홍그루,이상희,김영조,신동구,박종선,심봉섭,조정환,정선영,손창우 한국심초음파학회 2009 Journal of Cardiovascular Imaging (J Cardiovasc Im Vol.17 No.4

Pedunculated thrombus in the aortic arch that is associated with cerebral infarction is very rare requires prompt diagnosis and treatment to prevent occurrence of another devastating complication. Transesophageal echocardiography is useful for detecting source of embolism including aortic thrombi. The treatment options of aortic thrombi involves anticoagulation, thrombolysis, thromboaspiration, and thrombectomy. Here we report a case of huge thrombus in the aortic arch, resulting in acute multifocal cerebellar embolic infarct in patient without any risk factors for vascular thrombosis. Thrombi in the aortic arch were diagnosed by transesophageal echocardiography and treated with anticoagulants successfully. Pedunculated thrombus in the aortic arch that is associated with cerebral infarction is very rare requires prompt diagnosis and treatment to prevent occurrence of another devastating complication. Transesophageal echocardiography is useful for detecting source of embolism including aortic thrombi. The treatment options of aortic thrombi involves anticoagulation, thrombolysis, thromboaspiration, and thrombectomy. Here we report a case of huge thrombus in the aortic arch, resulting in acute multifocal cerebellar embolic infarct in patient without any risk factors for vascular thrombosis. Thrombi in the aortic arch were diagnosed by transesophageal echocardiography and treated with anticoagulants successfully.

사지 운동실조만으로 발현된 외측 연수경색

송인욱,안재영,김중석,류선영,이상봉,이승재,김영인,이광수 대한노인병학회 2008 Annals of geriatric medicine and research Vol.12 No.1

Pure limb ataxia without other common symptoms of Wallenberg syndrome has rarely been reported as manifestation of lateral medullary infarction. We describe a patient with lateral medullary infarction who presented with almost isolated right limb (mainly lower limb) ataxia without usual symptoms such as hemibody sensory changes, dysphagia, hoarseness, hiccup, and Horner sign. The brain magnetic resonance image showed small ischemic lesion involving the dorsolateral portion of the medulla oblongata.

하시모토 갑상선염 환자에서의 인슐린자가면역증후군 1예

송인욱,한유진,조난희,조호찬 대한갑상선학회 2014 International Journal of Thyroidology Vol.7 No.2

Insulin autoimmune syndrome (IAS) is characterized by fasting hypoglycemia, endogenous hyperinsulinemia, and the presence of autoantibodies to insulin or insulin receptor in patients that have never been exposed to exogenous insulin. This syndrome is occasionally accompanied by several autoimmune disorders. There is no reported case of concurrent IAS with Hashimoto's thyroiditis. A 52-year-old female was diagnosed with Hashimoto’s thyroiditis and was treated with 25 μg/d levothyroxine for 3 years. Recently, she experienced recurrent fasting hypoglycemic symptoms that disappeared rapidly with a carbohydrate-rich diet, although she had no history of diabetes or insulin use. Blood analysis showed hypoglycemia and elevated serum levels of insulin and C-peptide. Imaging studies did not reveal a mass lesion in the pancreas, and selective calcium-stimulated venous sampling also gave a negative result. However, anti-insulin antibody titer was high and assay for anti-insulin receptor antibody was positive. Here, we report a case of IAS concomitant with Hashimoto’s thyroiditis.

경상북도 장애인편의시설설치촉진사업 성과관리 평가지표 개발연구: 논리모형을 적용하여

송인욱,원서진,김동화 한국콘텐츠학회 2019 한국콘텐츠학회논문지 Vol.19 No.5

This study aims to address the needs and effectiveness of performance measurement system for convenient facilities support project for people with disabilities performed by local government. In addition, it is also to develop performance measurement index based on logic model. The researchers conducted literature review and focus group interview to develop the performance measurement index. Then, through the project managers and related professionals, the researchers tested validity of the measurement. The final measurement consisted of 38 questionnaires in 8 sectors. With this performance measurement system, we expect to establish rationalization of overall disability services. Also the theoretical framework and approach of performance measurement will be applicable to diverse public social service sectors. 본 연구는 지방자치단체가 수행하는 다양한 보조사업 중 장애인편의시설설치촉진사업에서 효과적이고 효율적인 성과관리 평가체계구축의 필요성과 실효성에 대해 논의하였다. 이와 함께 사회서비스 영역에서 성과평가시스템을 도입하면서 논리적 구조로 활용되는 논리모형을 적용하여 사회복지시설평가영역에 포함되지 않는 장애인편의시설설치촉진사업의 성과관리 평가지표를 개발함을 목적으로 한다. 이를 위해 문헌검토와 초점집단인터뷰를 통해 성과관리 평가지표를 개발하고 시범평가를 통해 평가지표의 타당성 및 평가용이성 분석을 실시한 후, 시범평가결과를 바탕으로 현장의견조사 및 전문가를 통한 타당성 검토를 진행하여 최종지표를 개발하였다. 최종 개발된 평가지표는 전체 8개 영역, 39개 문항으로 구성되었다. 장애인편의시설설치촉진사업 성과관리 평가체계 구축을 통해 장애인편의시설설치촉진사업 전반의 합리화를 추구하고자 하였으며, 본 연구에서 제시된 성과관리 평가지표의 개념틀과 평가접근 방식은 공공부문의 다양한 사회서비스 유형과 특성에 적합하게 활용될 수 있을 것이다.