뉴스리터러시 교육 연계 유아건강교육활동이 유아의 건강인식에 미치는 영향

김정은(Jung-Eun Kim),주봉관(Bong-Kwan Joo),김낙흥(Nak-Heung Kim) 중앙대학교 한국교육문제연구소 2020 한국교육문제연구 Vol.38 No.3

본 연구는 뉴스리터러시 교육과 연계한 건강교육활동을 구성하여 이를 유치원 현장에 적용한 후 유아의 건강인식에 미치는 영향을 알아보고자 하였다. 이러한 연구문제를 검증하기 위해 유치원의 만 4세 유아들을 대상으로 건강 관련 뉴스를 선정하고, 건강교육활동을 구성하여 실시하였다. 실험은 2017년 6월 21일부터 10월 20일까지 총 21회차에 걸쳐 진행되었으며, 연구대상은 경기도 성남시에 소재하고 있는 S유치원의 만 4세 A 학급과 B 학급의 유아들로 각각 20명의 유아를 실험집단과 비교집단으로 구성하였다. 본 연구는 유아의 건강인식 검사도구를 사용하여 사전·사후 검사를 실시하였고, 수집된 자료들은 SPSS 23.0 프로그램을 활용하여 t-검증을 실시하여 분석하였다. 연구 결과, 유아의 건강 인식 전체 점수에서 뉴스리터러시를 기반으로 한 건강교육 활동에 참여한 실험집단 유아들이 신체건강, 영양, 정신건강, 안전 모든 요소에서 비교집단보다 통계적으로 유의한 수준에서 높은 것으로 나타났다. 본 연구는 유아의 건강인식 함양을 위한 뉴스 활용 교육활동의 모델을 제시하고, 뉴스리터러시 교육의 현장 적용을 위한 실제적인 방안을 제공할 것으로 기대한다. The purpose of this study is to analyze the effects of young children’s health education knowledge related to news literacy. The subjects of this study are 40 four-year-old children in S kindergarten located in Jung-won Gu, Seong-nam. They were divided into an experiment group(n=20) or a control group(n=20). The study was conducted in this order: pretest, experimental treatment, posttest. Young children’s ideas of health perception was measured in both the pretest and posttest. The experiment had been conducted for 21 times from June 21 to October 20, 2017. A t-test was performed on the data collected through pretest and posttest using SPSS 23.0. The result of this study showed that health education activities related to news literacy have a positive effect on improving overall health perception. This study presents an educational model for utilizing news in early childhood health education, and provides an educational practice for applying news literacy to early childhood education.

식물 생명공학과 생물정보학

김정은,백효정,김영철,허철구,Kim, Jung-Eun,Paik, Hyo-Jung,Kim, Young-Cheol,Hur, Cheol-Goo 한국식물생명공학회 2006 식물생명공학회지 Vol.33 No.3

애기 장대와 벼의 전체 게놈 염기서열 분석이 완료되었고, 다량의 EST 데이터가 많은 식물에서 이용 가능하게 되었다. 또한, 방대한 양의 다양한 생물학적 데이터들이 transcriptomics, proteomics, metabolomics와 같은 여러 '-omics' 기술에 의하여 만들어져 왔다. 생물정보학은 이런 방대한 양의 생물학적 데이터로부터 유용한 정보를 얻는데 필수적이고도 매우 중요한 역할을 수행한다. 이 총설에서, 우리는 대량의 데이터를 생성하는 실험적 방법들과, 식물 병 저항성과 분자 육종과 같은 식물 연구분야로의 응용, 그리고 식물 생명공학의 연구 개발에 유용한 생물정보학적 기술과. 인터넷 정보 사이트들을 소개하였다. 우리는 새로운 실험 방법들과 생물정보학적 분석 기술들이 식물 생명공학 발전에 중요하게 기여할 것으로 기대하고 있으며, 생물정보학은 식물 생명공학의 연구 개발에 있어서 결정적인 요소가 될 것이라 생각한다. The whole genome sequence was completed in arabidopsis and rice. Large amounts of EST data have been available from many other plants. Also, vast quantities of diverse biological data have been generated by various '-omics' technologies such as transcriptomics, proteomics, and metabolomics. Bioinformatics plays an essential role in extracting useful information from these tremendous amounts of biological data. In this review we introduced experimental methods to generate massive data, applications to plant science such as plant disease resistance and molecular breeding and bioinformatics tools and web sites available in plant biotechnology R&D. We concluded that new experimental methods and bioinfomation analysis techniques have made major contributions to the development of plant biotechnology and that bioinformatics has become a critical factor in plant biotechnology R&D.

산후 약선식 개발을 위한 조선시대 관련의서 고찰 - 「향약집성방(鄕藥集成方)」, 「동의보감(東醫寶鑑)」, 「방약합편(方藥合編)」을 중심(中心)으로 -

김정은,김병숙,안지영,김윤경,Kim, Jung-Eun,Kim, Byung-Sook,Ahn, Ji-Young,Kim, Yun-Kyung 대한한의학방제학회 2013 대한한의학 방제학회지 Vol.21 No.2

Objectives : This study was carried out to investigate the traditional diet therapies for the period of postpartum recovery and lactation and to develop modern postpartum recovery foods. Korean traditional medical treatment for postpartum care focused on treating postpartum obesity, edema, agalactia was studied. Methods : We investigated the documents recorded in the medical classics of "Hyangyakjipseongbang(鄕藥集 成方)", "Donguibogam(東醫寶鑑)" and "Bangyakhappyeon(方藥合編)" published in 1433, 1613 and 1885 respectively in the Joseon Dynasty. Results : First, Radix Angelicae Sinensis was most frequently used to treat the postpartum obesity, and a lot of nourishing herbs including Radix Paeoniae Alba, Radix Astragali, Radix Ginseng, Rhizoma Chuanxiong were also used. Second, Radix Glycyrrhizae, Rhizoma Atractylodis Macrocephalase, Pericarpium Citri Reticulatae, Rhizoma Zingiberis Recens were used to treat the postpartum edema. Third, Radix Rhapontici, Medulla Tetrapanacis, Fructus Trichosanthis etc. were used to treat the postpartum agalactia. Conclusions : Consequently, we hope this study on the prescriptions and herbs for gynecology in "Hyangyakjipseongbang(鄕藥集成方)", "Donguibogam(東醫寶鑑)" and "Bangyakhappyeon(方藥合編)" will provide knowledge for diet therapy model development of postpartum care of the modern times.

서양종 꿀벌(Apis mellifera L.) 수벌번데기 동결건조 분말의 영양학적 성분 및 항산화 효과

김정은,김도익,구희연,김현진,김성연,이유범,김지수,김호혁,문제학,최용수,Kim, Jung-Eun,Kim, Do-Ik,Koo, Hui-Yeon,Kim, Hyeon-Jin,Kim, Seong-Yeon,Lee, Yoo-Beom,Kim, Ji-Soo,Kim, Ho-Hyuk,Moon, Jae-Hak,Choi, Yong-Soo 한국응용곤충학회 2020 한국응용곤충학회지 Vol.59 No.3

In this study, we analyzed the nutritional ingredients of drone pupae (16^th to 20^th instar old) to evaluate the value of bee products and provide basic data for product diversification, and the extracts prepared using these pupae were tested for physiological activity. According to the analysis of the general ingredients of the freeze-dried powder of these bee pupae, the moisture, crude protein, crude fat, and crude ash was 1.69 ± 0.07%, 48.52 ± 0.20%, 23.41 ± 0.14%, and 4.05 ± 0.02%, respectively. Vitamin C and vitamin E were 14.92 ± 0.52 mg/100 g and 6.06 ± 0.11 mg α-TE/100 g, respectively. Regarding minerals, the highest content of K (1349.13 ± 34.57 mg/100 g) and P (1323.55 ± 43.85 mg/100 g) was observed and Ca and Fe were 55.43 ± 1.51 mg/100 g and 5.49 ± 0.19 mg/100 g, respectively. The fatty acids of the water extracted freeze-dried pupae powder accounted for approximately 59.62 of saturated fatty acids and 40.38 of unsaturated fatty acids, and high-quality fatty acids such as palmitic acid (C16:0) was 35.49 ± 0.08 and oleic acid (C18:1, n-9) was 35.91 ± 0.22 (g/100 g total fatty acids). The total amino acid content was 38.99 ± 2.63 g/100 g and the free amino acid was a total of 5129.04 mg/100 g, of which 1257.68 mg/100 g was proline and 759.12 mg/100 g glutamic acid. The DPPH (1,1-diphenyl-2-picrylhydrazyl) radical scavenging activity of the drone pupae extract showed values of 0.8 for distilled water extract, 3.2 for 50% EtOH extract, 6.4 for 70% EtOH extract, and approximately 90% for 32 ㎍/mL for 100% EtOH extract. These results suggest that the main compound contributing to the antioxidant activity is a polar compound, and it is highly likely to be a low-molecular protein or a free amino acid. In conclusion, the honey bee drone pupa is excellent as a food resource and can be utilized as a new functional material for food and functional food.

폐경 후 고혈압 전단계 및 1기 고혈압에 대한 침 치료 효과: 무작위 대조 예비연구

김정은,최선미,최진봉,김형준,권오진,김재홍,박지은,Kim, Jung-Eun,Choi, Sun-Mi,Choi, Jin-Bong,Kim, Hyeong-Jun,Kwon, Ojin,Kim, Jae-Hong,Park, Ji-Eun 경락경혈학회 2017 Korean Journal of Acupuncture Vol.34 No.3

Objectives : The aim of this study was to assess the effectiveness of acupuncture in treating prehypertension and stage 1 hypertension in postmenopausal women. Methods : The study was a multi-center, four-arm, non-blinded, randomized clinical trial. Sixty participants were randomly assigned to experimental or control groups. The experimental groups received 10 acupuncture sessions over 4 weeks(Group A, n=20) or 20 sessions over 8 weeks(Group B, n=20) along with usual care. The acupoints were GB20, LI11, ST36, and SP6, bilaterally. The acupuncture groups were followed-up for an additional 12 weeks after acupuncture treatment. The control groups received usual care for 16 weeks(Group C, n=10) or 20 weeks(Group D, n=10). The outcomes were blood pressure, blood pressure control rates, lipid profile, and high-sensitivity C-reactive protein(hs-CRP). Results : After 4 weeks, DBP in the acupuncture groups(A+B) showed no significant decrease compared to the control group(C+D). However, after 8 weeks of acupuncture treatment, group B showed a significant decrease in DBP after acupuncture treatment and follow-up period compared to control group. Although there was no difference between the acupuncture and control groups in SBP after acupuncture treatment, group B showed a significant decrease in SBP compared to control group after follow-up period. Lipid profiles and hs-CRP did not differ significantly between acupuncture and control groups. Conclusions : Acupuncture treatment for 8 weeks showed the effect on prehypertension and mild hypertension. To verify the effect of acupuncture on blood pressure, rigorous trials including more participants are required.

사람 치은 섬유아세포에서의 Tannerella forsythia 전세균, 막단백질, 당지질에 의한 염증성 사이토카인 발현

김정은,이성훈,최봉규,구기태,김태일,이용무,구영,정종평,류인철,Kim, Jung-Eun,Lee, Sung-Hoon,Choi, Bong-Kyu,Koo, Ki-Tae,Kim, Tae-Il,Lee, Yong-Moo,Ku, Young,Chung, Chong-Pyoung,Rhyu, In-Chul 대한치주과학회 2008 Journal of Periodontal & Implant Science Vol.38 No.3

Purpose: The purpose of this study was to investigate induction of cytokine expression in human gingival fibroblasts (HGFs) by whole cell and the components of T. forsythia. Material and Methods: After HGFs were treated with lipopolysaccharide (LPS), membrane protein isolated from T. forsythia or culture media of T. forsythia, the induction of interleukin (IL)-1, IL-6 and IL-8 was examined with real-time PCR and ELISA. Their induction ability of cytokines was compared with whole bacteria. Result: The expression of IL-6 and IL-8 was significantly induced in HGFs by whole bacteria and membrane protein. The expression of IL-$1{\beta}$ was induced by membrane protein of T. forsythia, not by whole bacteria. LPS and condition media of T. forsythia slightly activated HGFs. Conclusion: The membrane protein of T. forsythia could be one of virulence factors.

성장호르몬분비 뇌하수체 선종 80예의 수술성적 및 예후 인자의 분석

김정은,정희원,곽호신,백선하,김동규,최길수,Kim, Jeong Eun,Jung, Hee-Won,Gwak, Ho-Shin,Paek, Sun Ha,Kim, Dong Gyu,Choi, Kil Soo 대한신경외과학회 2000 Journal of Korean neurosurgical society Vol.29 No.6

Objectives : The surgical results of 80 patients with growth hormone(GH)-producing pituitary adenoma were analyzed retrospectively to evaluate the clinical manifestations and to determine which preoperative factors significantly influenced the surgical outcome. Patients and Methods : The patients consisted of 39 men and 41 women and the age of patients at the time of initial operation ranged from 17 to 67 years(mean age, 40.5 years) Between January 1990 and June 1996, 77 patients underwent transsphenoidal surgery and 3 patients underwent craniotomy for GH-producing pituitary adenoma at our institution. Preoperative administration of octreotide was performed in 18 patients. Surgical control was defined as a postoperative serum basal level of GH less than 5ng/ml. A logistic regression model was used for univariate and multivariate analysis. Probability value of less than 0.05 was considered as statistically significant. Results : The most common presenting symptom was acromegaly, followed by headache, visual disturbance, and fatigability. Visual symptoms were present in 39% of the patients. Diabetes mellitus was associated in 24 patients and hypertension in 12. Preoperative mean basal level of GH was 93.2ng/ml(range 72-500ng/ml) which was closely related with tumor size(p<0.05). Grade II by Hardy's classification was the most common radiological type. Preoperative octreotide treatment significantly reduced the level of GH(p<0.05), but not enough to induce endocrinological remission. One patient died of cerebral infarction after craniotomy. The most common surgical complication was transient diabetes insipidus. The symptom of the earliest improvement after surgery was paresthesia and tightness of the hand and foot, followed by headache and easy fatigability. The preoperative visual symptom was improved in all patients. The patients who had hypertension or DM experienced alleviated symptoms in 67% and 92%, respectively. The overall rate of endocrinological remission was 44%. By multivariate logistic regression analysis, the size of tumor, extrasellar extension, and extent of removal were significant prognostic factors for endocrinologial remission. Conclusion : Early detection of a small tumor without extrasellar extension followed by a complete resection is highly recommended in order to achieve endocrinological cure of GH-producing pituitary adenomas.

유통 패류의 중금속 및 패류독소 분석

김정은,황선일,이성봉,신상운,권혜정,이지연,이병훈,모아라,최옥경,Kim, Jeong-Eun,Hwang, Seon-Il,Lee, Seong-Bong,Shin, Sang-Woon,Kwon, Hye-Jung,Lee, Ji-Yeon,Lee, Byoung-Hoon,Mo, A-Ra,Choi, Ok-Kyung 한국식품위생안전성학회 2022 한국식품위생안전성학회지 Vol.37 No.3

본 연구에서는 유통 패류 104건을 대상으로 중금속(납, 카드뮴, 수은) 및 패류독소(설사성 패류독소, 기억상실성 패류독소) 실태조사를 하였다. 중금속 분석 결과, 납의 검출범위는 0.0177-0.5709 mg/kg, 카드뮴의 검출범위는 0.0226-1.4602 mg/kg, 수은의 검출범위는 0.0015-0.0327 mg/kg이었으며, 모두 국내 기준 이하로 안전한 수준이었다. 설사성 패류독소 모니터링을 위해 okadaic acid와 dinophysistoxin-1을 분석하였고, 그 결과 104건 모두 불검출이었다. 기억상실성 패류독소인 domoic acid를 분석한 결과, domoic acid가 검출된 것은 5건으로 4.8%의 검출률을 보였다. 기억상실성 패류독소가 검출된 시기는 각각 1월 1건, 2월 1건, 5월 1건, 9월 2건이 검출되어 패류독소에 대한 지속적인 모니터링이 필요할 것으로 판단된다. 또 패류 내 중금속은 기준 규격 이내로 안전한 수준이라 하더라도 중금속 오염에 대한 지속적인 안전관리가 필요하고, 향후 수산물 중금속에 대한 안전관리 강화를 위한 기초자료로 제공하고자 한다.

60세 이상 노인 인구에서 우울증과 자살의 위험인자

김정은(Jeong Eun Kim),신동환(Dong Hwan Shin),윤성욱(Sung Wook Yoon),백준형(Jun Hyung Baek),전동욱(Dong Wook Jeon),문정준(Jung Joon Moon),이봉주(Bong Ju Lee),김영훈(Young Hoon Kim) 대한생물치료정신의학회 2010 생물치료정신의학 Vol.16 No.1

Objectives:In this study authors evaluated depressed mood and suicidal ideation among the elderly over 60 years old. We also investigated sociodemographic and clinical risk factors of depression and suicide. Methods:Six hundred fifty elderlies participated in this study. One hundred seventy nine subjects agreed to laboratory test and more evaluation. Geriatric Depression Scale(GDS) and Scale for Suicidal Ideation(SSI) were used to evaluate depression and suicidal ideation. Participants whose GDS score was 17 or more were concluded to have depressed mood, whose SSI score was 9 or more were concluded to have suicidal ideation. Results:The prevalence of depression and suicidal ideation in Korean elderly over 60 years old were 65.4%, 13.9% respectively. Female sex, low education state, low MMSE-KC score, high Hachinski ischemic score and high SSI score were significantly related with depression. Suicidal ideation was related with hypertension history. But MMSE-KC, GDS, SSI and serum lipid levels showed no significance in this study. Conclusion:Compared with other studies, the prevalence of depression in Korean elderly over 60 years old was higher. The risk factors of depression were female sex, low education state, cognitive impairment and risk of brain vascular disease. And the risk factor of suicidal ideation was hypertension history. But cognitive impairment, depression and suicidal ideation were not significantly correlated with serum lipid levels. To confirm this result, well-designed and wide range studys will be needed.

장기간 혈액 투석증인 환자에서 혈청 Prolactin 변동에 대한 연구

김정은(Jung Eun Kim),이병철(Bung Chul Lee),김원(Won Kim),박성광(Sung Kwang Park),강성귀(Sung Kyew Kang) 대한내과학회 1998 대한내과학회지 Vol.55 No.3

Background: The kidney plays an important role in excretion and catabolization of hormones in body. The possible role of hyperprolactinemia in the sexual abnormalities of patients with end stage renal disease was reported. So, we evaulated the prolactin levels in patients undergoing long-term hemodialysis and the response to bromocriptine. Methods: Basal um levels of prolactin were measured in 11 patients undergoing long term hemodialysis by enzyme immunoassay. Blood samples were drawn just before dialysis and at the end of same dialysis session. We also examined 11 male normal person as controls. We evaluated the sexaul activity and serum prolactin level after administration of bromacriptine to the patients with hyperprolactinemia for 6 weeks. Results: The average age of 11 male patients undergoing long-term hemodialysis was 40.2 years, The patients has been received hemodialysis for 38.5 months at time of the study. Prolactin levels in patients under- going hemodialysis before hamdialysis were 2M5.1 mIU/L, after hemodialysis Z341.2 mIU/L, and normal male persons 212.8 mIU/L. Serum prolactin levels were decreased progressively for 2 week after oral administration of bromocriptine. Thereafter, prolactin were maintained within normal value until from 4th weeks to 8th weeks. Sexual activity in end stage renal disease patients with hyperprolactinemia was markedly improved after 6th weeks. Conclusions: The serum prolactin levels in patients undergoing long-term hemodialysis were higher than that of the controls. The high serum prolactin level may be related with decreased sexual function. 1n patients with decreased sexual function, treatment with dopamine agonist can decreased serum prolactin levels and can improve symptoms such as decreased libido and impotence.