Poster Session : PS 0831 ; Upper GI Tract : Clinical Factors to Predict Angiographically Detectable Non-Variceal Upper Gastrointestinal Bleeding in Patients Refractory to Endoscopic Treatment

( Tae Hwan Ha ),( Tae Hoon Oh ),( Sung In Yu ),( Min Kim ),( Jong Wook Kim ),( Won Ki Bae ),( Jae Hyung Kim ),( Seung Suk Baek ),( Mi Jin Ryu ),( Ye Na Choi ),( Ji Young Park ),( Eileen L Yoon ),( Tae 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

Background: Non-variceal upper GI bleeding (NVUGIB) is a common medical problem that has signifi cant association with morbidity and mortality. Angiographic detection and subsequent transarterial embolization (TAE) is a primary treatment option when medical and endoscopic treatments fail. We investigated clinical factors that could affect the success of the angiographic detection and prognosis after TAE in patients with NVUGIB refractory to endoscopic therapy. Methods: A retrospective analysis of the clinical data was done in patients with failed endoscopic treatment who underwent angiography for the treatment of acute NVUGIB between May 2002 and May 2013. Patients were divided into detection or non-detection groups according to the presence of bleeding stigmata in angiographic fi nding. Rebleeding defi ned as subsequent bleeding event within 7 days and mortality within 30days were analyzed as outcome parameters after TAE following detection in angiography. Results: A total 45 patients 37 (male, mean age, 65.9±14.9 years) were analyzed and classifi ed as a detection group (n=25, 55.5%) and non-detection group (n=20, 44.6%). Peptic ulcers were the most common cause of refractory NVUGIB. Larger transfusion amount (5.7±3.9 unit vs. 3.5±2.8 unit; P=0.03), prolonged aPTT level (34.2±17.3 sec vs. 21.8±13.8 sec; P=0.01) and short time interval between last endoscopy and angiography (17.5±25.9 hours vs. 34.3±59.5 hours; P=0.04) were found to be signifi cant factors for predicting angiographic detection. TAE was performed in all patients detected in angiography. Rebleeding (44%) was significantly associated with higher Rockall score (8.3±1.5 vs. 6.6±2.4; P=0.046) and mortality (12%) was signifi cantly associated with higher Rockall score (9.3±0.6 vs. 7.1±2.2; P=0.002) and higher level of BUN (55.3±47.4 vs. 27.6±17.4; P=0.01). Conclusions: Clinical characteristics associated with angiographic detection in patients with NVUGIB refractory to endoscopic therapy were severe bleeding, bleeding tendency and early angiographic intervention. The Rockall score is useful parameter for predicting rebleeding and mortality after TAE.

Peroxiredoxin V Regulates Aco2, Acadm, and Acox1 Activity in Hypoxic Kidney

Tae‐Hoon Lee,Hee‐Young Yang,Joseph Kwon,Hoon‐In Choi,Lina Ren,Ung Yang,Byung‐Ju Park,Zae Young Ryoo 한국동물생명공학회(구 한국동물번식학회) 2011 발생공학 국제심포지엄 및 학술대회 Vol.2011 No.1

Peroxiredoxin V, an atypical thioredoxin peroxidase, is widely expressed in mammalian tissues. In addition, Prdx V is localized in mitochondria, peroxisome, cytosol, and nucleus. Prdx V has been reported to protect a wide range of cellular environments as antioxidant enzyme, and its dysfunctions may be implicated in several diseases, such as cancer, inflammation, and neurodegenerative disease. Identification and relative quantification of proteins affected by Prdx V may help identify novel signaling mechanisms that are important for oxidative stress response. However, the role of Prdx V in the modulation of hypoxia‐related cellular response is not studied yet. In order to examine the function of endogenous Prdx V in hypoxic condition in vivo, we generated a transgenic mouse model with Prdx V siRNA expression controlled by U6 promoter. Of many tissues, the knockdown of Prdx V expression was displayed in kidney, lung, and liver, but not spleen and skin. We conducted on the basis of nano‐UPLC‐MSE proteomic study to identify the Prdx V‐affected protein networks in hypoxic kidneys. In this study, we identified protein networks associated with oxidative stress, fatty acid metabolism, and mitochondrial dysfunction. Our results indicated that Prdx V affected to regulation of kidney homeostasis under hypoxia stress.

성대마비환자를 대상으로 시행한 후두근전도검사의 임상적 유용성

최홍식,최영준,문상우,김태만,최홍식,최영준,문상우,김태만 대한이비인후과학회 1999 대한이비인후과학회지 두경부외과학 Vol.42 No.2

영·유아 언어, 인지, 사회·정서 발달 평가도구 문항 개발을 위한 예비연구

이종숙,신은수,박은혜,김영태,유영의,최일선,유흥옥 이화여자대학교 교육과학연구소 2009 교육과학연구 Vol.40 No.3

본 연구는 만 2~5세 영·유아의 발달 상태를 객관적으로 평가함과 동시에 발달이 지연된 영·유아를 선별할 수 있는 발달평가도구 문항을 개발하기 위한 예비연구이다. 이를 위해 문헌고찰 및 발달관련 평가도구들을 비교 분석하여 발달지표를 선정하고, 만 2세~5세까지의 영·유아의 언어, 인지, 사회·정서발달영역을 교사관찰에 기초하여 평가할 수 있는 문항을 개발하였다. 연구대상은 대도시, 중소도시, 읍면 소재지 별로 표집 된 만 2세부터 5세까지 총 13개 유아교육기관에 다니는 435명의 영·유아들이며, 본 연구에서 최종 개발된 평가도구의 문항은 총 141문항이다. 평가도구 문항은 언어, 인지, 사회·정서발달영역별로 영·유아의 행동과 언어를 중심으로 교사가 관찰하고, 관찰하기 어려운 문항에 대해서는 단서와 kit를 제시하여 평가할 수 있도록 구성하였다. 개발된 평가도구 문항의 적절성을 알아보기 위하여 내용 타당도와 내적 신뢰도를 살펴본 결과 비교적 양호한 것으로 나타났다. This was a preliminary study to construct a developmental rating scale for understanding children's objective developmental levels and screening developmental disabilities. For this purpose, a developmental indicator was selected by a literature review and comparative analysis of related developmental assessment tests. An assessment scale based on teacher's observations to measure language, recognition, and social-emotional developmental areas was developed. The subjects were 435 young children aged 2 to 5 who lived in both urban and rural areas. A trial test consisted of 141 assessment items in the language, recognition, and social-emotional developmental domains. The developmental scale was evaluated by teachers who observed children's behavior and language, and used clues and kits. Tests on validity and reliability for confirming the appropriateness of the developed assessment scale showed that content was relatively valid and internally consistent.

재발성 류마티즘 환자에서 발작의 유발인자

주유철,이동민,양종태,신병철,임태영,서정균,정기영,최동헌,김원,조영신,고희관 조선대학교 2001 The Medical Journal of Chosun University Vol.26 No.2

Background and Objectives : Palindromic rheumatism (PR) is known to be triggered without any obviously inciting events in most patients, although, in a few cases, attacks have been noted to relate to another events such as weather change, childbirth, ingestion of certain foods, or over-exercise. The aim of this study was to characterize the triggering factors on palindromic attacks. Materials and Methods : We evaluated sixty-four patients with PR for the presence of triggering factors and the relationship between attacks and triggering factors by interview of patients. We considered that there was an probable association between episodes and PR, if episodes within 24 hours prior to PR had triggered at least 50% of all attacks and a definite association between episodes and PR, if episodes within 24 hours prior to PR had triggered 100% of all attacks. Results : In 15 patients (35.9%), there was a possible association between episodes of PR and initiating events. In 8 patients (12.5%), there was a definite association between episodes of PR and initiating events. The triggering factors were physical over-activity including exercise (19/64: 29.7%), foods, such as rawfish, crab, and chicken, including alcohol (19/96: 19.8%). However, there were no difference between the groups with and without the triggering factor in sex ratio, duration and onset of PR, the positive rate of rheumatoid factor and involved sites. Conclusion : Our observations showed that PR was triggered by physical over-activity more than in previous reports and hypersensitivity to foods was a causative factor in some patients with PR. However, patients with triggering factors had a similiar clinical profile to patients without triggering factors.

21가지 장미꽃 품종의 페놀성 화합물 함량 및 항산화 활성

조연재(Yeon Jae Jo),서정현(Jeong Hyun Seo),홍채영(Chae Young Hong),김성태(Seung Tae Kim),최은경(Ehn-Kyoung Choi),김윤배(Yun-Bae Kim),이준수(Junsoo Lee),정헌상(Heon Sang Jeong) 한국식품영양과학회 2021 한국식품영양과학회지 Vol.50 No.4

본 연구는 21품종의 장미꽃에 대한 식품 및 화장품 원료로 사용 가능성을 살펴보기 위해 페놀성 화합물과 항산화 활성을 평가하였다. 총 폴리페놀, 총 플라보노이드 및 타닌 함량은 러버샤이 품종에서 각각 379.70 mg GAE/extract g, 50.10 mg CE/extract g 및 339.44 mg TAE/extract g으로 높게 나타났으며, 칠백리 품종에서 각각 107.25 mg GAE/extract g, 9.46 mg CE/extract g 및 36.31 mg TAE/extract g으로 낮았다. 페놀산 함량은 총 폴리페놀 함량과 유사한 결과를 보였으며, 러버샤이 품종에서 27.40 mg/extract g으로 높았다. 안토시아닌은 대부분 cyanidin-3,5-diglucoside로 확인되었으며 총 안토시아닌 함량은 유니나 품종에서 8.80 mg/extract g으로 가장 높았다. ABTS 및 DPPH 라디칼 소거 활성은 각각 428.10 및 419.59 mg AAE/extract g로 러버샤이 품종에서 가장 높았으며, 항산화 활성과 페놀 화합물의 함량과 높은 양의 상관관계를 보였다. 이러한 결과는 러버샤이와 같은 항산화 활성이 뛰어난 품종들이 관상 목적뿐만 아니라 높은 기능성을 가진 식품 및 화장품의 원료로 사용 가능성이 있다고 판단된다. This study evaluated the functional components and antioxidant activities of 21 different rose flower extracts, to confirm their value as a food and cosmetics ingredient. The highest values of total polyphenol, flavonoid and tannin contents (379.70±1.64 mg GAE/extract g, 50.10±0.76 mg CE/extract g, and 339.44±1.20 mg TAE/extract g, respectively) were obtained in Lover Shy. The proanthocyanidin content ranged from 61.88 mg CE/extract g in the Unina cultivar to 5.34±0.13 mg CE/extract g in the Aileen cultivar. The phenolic acid content obtained was highest in the Lover Shy cultivar (27.40±0.26 mg/extract g), whereas highest levels of anthocyanin (8.83±0.03 mg/extract g) were obtained in the Unina cultivar. High ABTS and DPPH radical scavenging activities were determined in the Lover Shy cultivar (428.10±0.29 and 419.59±3.12 mg AAE/extract g, respectively). Taken together, these results indicate that the antioxidant activity and functional components of Lover Shy cultivar are superior, and this extract can potentially be applied as a food and cosmetic ingredient.

대구·경북지역 콘크리트용 부순모래의 품질조사

최영화,김종인,전성태 大邱大學校 科學技術硏究所 1998 科學技術硏究 Vol.5 No.4

This study is aimed for investigating the quality of crushed sand, manufactured in Taegu kyungpook region, random sampled according to the quality regulation of crushed sand for concrete, and analyzing application as a fine aggregate for concrete. By the test results, the FM of crushed sand is average 3.51 and appears very larger than that of river sand, the specific gravity of crushed sand is larger than that of river sand and satisfies the K.S regulation that more than 2.5, and the amount of material finer than NO.200 sieve in crushed sand appears average 4.9%, and satisfies the K.S regulation that less than 7%. The void ratio in crushed sand appears smaller than that of river sand, the unit weight of crushed sand appears larger than that of river sand, and the solid volume ratio and the net shape ratio of crushed sand satisfy the K.S regulation that more than 53%. After all, it is considered that manufactured crushed sand would be sufficiently used as a fine aggregate for concrete. Futhermore, if possible, the combined sand of river and crushed sand would be very effective in the aspect of economical efficiency and quality of concrete.

요통 환자에서 요통 및 방사통과 요추 자기공명영상의 이상소견에 대한 Tree모형의 활용

최영칠,손은주,이태용 건국대학교 의과학연구소 2002 건국의과학학술지 Vol.12 No.-

To detect the MRI findings related to The low back pain and sciatica according to age group, authors used tree model analysis of 80 patient's grading their low back pain and sciatica, with their lumbar MRI findings. And the results were as follows: 1. In teens and twenties(n=22), the low back pain was related to high maximum of spinal canal narrowing and large sum of disc degeneration, and the sciatica was related to the psoas spine ratio. 2. In thirties and forties(n=33), the sum of disc degeneration, the sum of foraminal narrowing, the maximum of disc degeneration affected the low back pain, and the sum of disc degeneration, disc herniation and maximum of canal narrowing were related to sciatica. 3. In fifties and sixties(n=23) the low back pain was related to large sum of foraminal narrowing and small psoas spine ratio, and thesciatica was largely affected by high maximum of foraminal narrowing and some by large sum of canal narrowing and large sum of disc degeneration.

기계식 주차설비 관제정산 시스템 개발

최동진,김태효,박영석 慶南大學校 附設 工業技術硏究所 1999 硏究論文集 Vol.17 No.-

본 논문에서는 기존 주차설비 자동화 기술의 문제점을 극복하기 위해서 자동 주차타워 관리용 관제정산 시스템의 객체지향 개발접근법을 제시한다. 개발된 주차설비 관제정산 시스템은 주차설비 제어장치와 정산 장치를 직렬 통신으로 결합한 하드웨어와 관제정산 소프트웨어로 구성된다. 관제정산 소프트웨어는 GUI 환경 하에서 객체지형 분석법을 통해 설계되고 Delphi 개발도구를 통해 구현되었다. 기존 시스템과는 달리 주차설비 조작, 주차증발행 및 인식, 요금정산 등을 일체화함으로써 사용상의 번거로움과 불편을 해소하고, 주차설비의 작동상태를 실시간으로 모니터링함으로써 높은 안전성을 제공한다. 또한 주차차량정보 및 주차관리기능을 통해서 주차 요금정산의 정확성 및 신뢰성 향상을 크게 기대할 수 있다. In this paper. in order to overcome the problems of the current automated parking systems, we propose an object-oriented development method of the control and account system for the management of automated parking tower. The developed system consists of the hardware, including the account unit and the parking control unit, and the control and account software. The hardware units are connected by serial communication line. The control and account software was designed through the object-oriented analysis approach and implemented by using Delphi development tool under GUI environment. Our system can minimize the difficulties and inconvenience of the use because of functioning as a total system, and provide the high safety of the parking operation by monitoring the parking status in real time. A1so it can greatly improve the correctness and reliability of accounting the parking fee.

신생아의 두뇌 초음파검사상 뇌실주위 고반향음영에 관한 연구

최영칠,이태용,조영채,이동배 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1

Neurosonography is an excellent modality for imaging a wide array of intracranial pathology of the infant and the newborn. Periventricular high echos were prominent for the premature infant, but there are some difficulties in differentiate normal periventricular high echo from periventricular leukomalacia. White matter indices on neurosonography of 152 healthy newborn babies were measured and analized, with their gestational age, method of delivery, birth weight, APGAR score(1 min and 5 min), diagnosis and labaratory data. The gestational age of babies at birth (p=0.0001) and the delivery with Caesarian section (p=0.0263) were related statistcally to high white matter index. The babies with metabolic disease had higher white matter index than other disease group or normal control group. On the basis of these results, We speculate that in addition to gestational age of infants, delivery method and their disease status may play an additional role in presenting ldgh periventricular echo on neurosonography. It is possible to predict the size of non pathologic periventricular high echo and to give more information for further study plan.