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      • 자기 효능의 개념 분석

        서순림,이은남,박송자,양영희,이동숙,최은옥,구미옥,김인자,이인숙,김성재,박영임,이은옥 서울대학교 간호대학 간호과학연구소 1997 간호학 논문집 Vol.11 No.1

        Today human needs for health promotion and maintenance are increasing. The nursing progression has a great responsibility for helping clients to practice good health behavior. self efficacy was found to be potent predictor in initiating and maintaining the health-related behavior. Therefore, the concept is important in nursig intervention for change of health behavior. The purpose of this paper was to analyze and clarify the meaning of the concept, self efficacy. This study used Walder & Avant's process of concept analysis. Critical attributes of self efficacy were : 1) positive perception of his won capability; 2) intrapersonal strength; 3) possibility of being learned; 4) individuality; 5) specificity; 6) generalizability. Antecedents of self efficacy consist of those facts that 1) new situation occurs; 2) individuals have needs to change the new situation; 3) there are some required actions in new situation. Consequences occurring as a result of self efficacy consist of those facts that 1) individual initiates the of failure; 5) cope with the situation; 6) controls the situation; 7) the level of self efficacy is enhanced; 8) the level of self-esteem is enhanced.

      • SCOPUSSCIEKCI등재

        Effects of Intravenous Adminitration of Nimodipine on Cerbal Pial Vessels after Experimental Subarachnoid Hemorrhage in Rabbits

        Hwang, Soon Gu,Lee, Young Woo 대한신경외과학회 1993 Journal of Korean neurosurgical society Vol.22 No.7

        가토에서 대조내 자가 신선혈 0.2㎖를 주입 후 6시간에 생리식염수와 여러 농도의 운nimodipine 용액(10, 30 및 60㎍/㎏)을 각각 정맥주사하여 야기되는 뇌연막혈관들의 반응(직경변화)을 연구하였다. 혈관의 측정은 개두술 후 수술현미경 최고 확대(40×)하에서 현미경의 대안렌즈에 Filar micrometer eyepiece(424 and 426, AO)을 부착하여 시행하였다. 이 Filar micrometer eyepiece의 한 눈금은 3.4㎛로 매우 미세한 소혈관까지 직접 측정할 수 있었다. PaO₂, PaCO₂ 및 동맥혈 pH는 대개 전 실험을 통해서 의의있는 변화를 보이지 않았다. 수축기 동맥압은 nimodipine 용액 주입 직후에 다소의 하강을 보였으나(p<0.05) 이러한 변화는 수축기 동맥압의 일시적인 하강현상이고 곧 정상 수준으로 복귀했다. 실험적 뇌지주막하 출혈 6시간 후 nimodipine 용액과 동일한 량의 생리식염수를 주입하였을 때 뇌연막혈관의 반응은 미미하여 그 통계학적 의의는 없었다(p>0.05). 그러나 nimodipine 용액을 정주하였을 때는 Group Ⅰ, Group Ⅱ 그리고 Group Ⅲ 모두에서 뇌연막혈관의 확장을 보였다. 이러한 혈관의 확장은 동맥, 특히 소동맥에서 현저한 양상을 보였으며 대연막동맥에서도 상당히 의의있는 혈관 확장을 보이기는 했으나 소연막동맥에서만큼 현저하지는 않았다. 이러한 뇌 연막동맥의 확장은 약물 주입 후 5, 10분에 가장 뚜렷하였으며 그 후는 시간이 경과함에따라 혈관의 직경이 서서히 감소하는 양상을 보였다. 뇌연막정맥의 경우에도 nimodipine용액의 정주 후 미약한 정도의 혈관확장을 보였으나 그 확장된 정도는 뇌연막동맥에 비해 미미하였으며 통계학적 의의도 적거나 없었다. 뇌연막동맥의 nimodipine에 대한 반응은 10, 30 그리고 60㎍/㎏의 약물 양의 변화에 비교적 민감하여 용량에 비례하는 소견을 보였다. 이상의 결과에서 뇌 지주막하 출혈이 야기된 실험동물에 nimodipine을 정주했을 때 뇌연막동맥의 현저한 확장이 야기되며 특히 소동맥이 민감하게 확장되는 사실은 뇌지주막하출혈에 의한 뇌허혈성 질환에 있어 nimodipine의 치료적 유용성을 입증할 수 있는 좋은 증거가 될 것으로 생각되며 그 효능은 정주된 실험약물의 양에 비례하였다. 이로서 부작용이 허용되는 범위 내에서 다량의 nimodipine을 허혈성 뇌혈관질환에 사용하여 치료적인 효과를 기대할 수 있을 것이라 생각된다. The author have studied effects of intravenous injection of normal saline and nimodipine solution(10, 30 and 60㎍/㎏) on cerebral pial vessels at 6 hours after experimental subarachnoid hemorrhage. Measurement of pial vessels were performed under operation microscope through the bilateral craniectomy area. Filar micrometer eyepiece was attached on the oculus of microscope(40×) to make it easier to measure fine pial vessels directly. Measuring unit of this micrometer eyepiece was 3.4㎛. Physilogic parameters(PaO₂, blood pH) generally did not show significant change all through the experiments except that systolic blood pressure showed temporary decrease immediately after the injection of nimodipine solution, which returned to base level soon. Small pial arteries were by far most effectively dilated by intravenous injection of nimodipine solution especially in 5 minutes. Large arteries also presented significant dilatation after the injection. The arteries were dilated as dose-dependent manner. Veins showed dilatation to the lesser degree than arteries independent of dosage of nimodipine, that was statistically of no significance. Conclusively, nimodipine might be used in treatment of vasospasm in subarachnoid hemorrhage in practice.

      • Molecular Cloning, Expression and Genomic Structure of Glyceraldehyde-3-Phosphate Dehydrogenase from the Entomopathogenic fungus, Paecilomyces tenuipes Jocheon-1

        Nam Sook Park,Han Seok Kang,Seon Ku Kim,Yong Gyun Kim,Byung Uuk Cho,Teak Soon Shin,Keun Ki Kim,Hyun Chul Park,Hong Joo Son,Hong Gu Lee,Sang Mong Lee 한국응용곤충학회 2011 한국응용곤충학회 학술대회논문집 Vol.2011 No.05

        Presently, We have constructed an olig-d(T) primed directional cDNA library from the silkworm Dongchunghacho, an entomopathogenic fungus, of which species is belonging to Paecilomyces tenuipes Jocheon-1. To isolate and screen genes in the fungus, 626 expressed sequence tags(ESTs) were generated by a partial sequencing from the cDNA library. Paecilomyces tenuipes Jocheon-1 cDNA encoding the glyceraldehyde-3-phosphate dehydrogenase(Pt-GAPDH) of Paecilomyces tenuipes Jocheon-1 was cloned from the above cDNA library. The complete cDNA sequence of Pt-GAPDHis comprised of 1,014bp encoding 338 amino acid residues. The deduced protein sequence of Pt-GAPDH showed higher homology with Beauberia bassiana-GAPDH(93% amino acid identity). Hydropathy analysis revealed that Pt-GAPDH protein is hydrophilic. The major three amino acids in its composition of amino acid residues were alanine(11.54%), valine(9.47%) and glycine(8.88%). The cDNA encoding Pt-GAPDH was expressed as a 37 kDa polypeptide in baculovirus-infected insect Sf9 cells. The Pt-GAPDH gene of Paecilomyces tenuipes entomopathogenic fungus consisted of three exons and two introns coding for 338 amino acid residues, and the genomic DNA length of the gene spans 1302bp. The accession number of the gene in GenBank are GU997099 for Pt-GAPDH cDNA and GU997102 for Pt-GAPDH genomic DNA.

      • cDNA Cloning and Genomic Structure of Glyceraldehyde-3-Phosphate Dehydrogenase from the Entomopathogenic fungus, Paecilomyces tenuipes-Jocheon

        Nam Sook Park,Han Seok Kang,Seon Ku Kim,Yong Gyun Kim,Byung Uuk Cho,Teak Soon Shin,Keun Ki Kim,Hyun Chul Park,Hong Joo Son,Hong Gu Lee,Sang Mong Lee 한국응용곤충학회 2010 한국응용곤충학회 학술대회논문집 Vol.2010 No.05

        Fungi belonging to the Paecilomyces spp. have recently been used as food and herbal medicines in Korea and are greatly popular as commercially available powdered supplement or dried fruiting body. Despite this acceptance and its use, little is known of the genes related to its reactive agents. Presently, We have constructed an olig-d(T) primed directional cDNA library from the silkworm Dongchunghacho, an entomopathogenic fungus, of which species is belonging to Paecilomyces spp. based on the previous identification of ITS1 and ITS2 at the molecular level and collected from Jocheon Miryang, Korea. To isolate and screen genes in the fungus, 626 expressed sequence tags(ESTs) were generated by a partial sequencing from the cDNA library. cDNA encoding the glyceraldehyde-3-phosphate dehydrogenase(Pt-GAPDH) of Paecilomyces tenuipes- Jocheon was cloned from the above cDNA library. The complete cDNA sequence of Pt-GAPDH is comprised of 1,014bp encoding 338 amino acid residues. The deduced protein sequence of Pt-GAPDH showed higher homology with Beauberia bassiana-GAPDH(93% amino acid identity). Hydropathy analysis revealed that Pt-GAPDH protein is hydrophilic. The major three amino acids in its composition of amino acid residues were alanine(11.54%), valine(9.47%) and glycine(8.88%). The Pt-GAPDH gene of Paecilomyces tenuipes entomopathogenic fungus consisted of three exons and two introns coding for 338 amino acid residues, and the genomic DNA length of the gene spans 1302bp. The accession number of the gene in GenBank are GU997099 for Pt-GAPDH cDNA and GU997102 for Pt-GAPDH genomic DNA. More investigation works including gene expression, immunological analysis etc. will be carried continuously without hesitation after this presentation.

      • 호텔 종사원의 승진에 따른 경력개발프로그램에 관한 연구

        이순구 한국관광정보학회 2002 觀光情報硏究 Vol.- No.12

        With the change of hotel management environment, hotel administrations need more experts to meet the various guest expectation. There is need for a effective career development program. Despite the importance of this issue, presently, there is little being done in the working area. In order to cultivate the men of talent, the Career Development Program by promotion of Hotel staffs will be needed. For this study, case studies of international hotels and review of current literature were conducted in order to develop new Career Development Program. In order to improve current career development programs, hotel managers must define a clear career purpose. It is also crucial that hotel management promote various career development programs encouraging those for whom ti is appropriate to participate. In the end, the hotel industry must support career development programs that recognize and meet the needs of a work force with diverse goals and managers must recognize and steps toward career satisfaction.

      • KCI등재
      • 국내에서 유행하는 HIV의 전파 경로에 따른 Subtype 분포

        이주실,남정구,김성순,강춘,최병선,김옥진,박미선,성봉모,서순덕,전수경,변승옥,신영오,조해월 대한감염학회 2001 감염 Vol.33 No.5

        Background : Previous data have been reported that subtype B is prevalent in South Korea, but neither the extent nor the proportion of subtypes could be evaluated. This study was designed to analyze the distribution of HIV-1 subtypes, temporal instructions and transmission dynamics between epidemiological groups. Methods : 1,280 Koreans had been diagnosed as HIV seropositive during the period 1985 to 2000. Among them, 134 individuals were selected for this molecular epidemiological study. 134 DNAs were isolated from uncultured or cultured peripheral blood mononuclear cells. V3-V5 (0.7 kb) fragment of HIV-1 env gene was amplified by nested polymerase chain reaction and was sequenced. Results : HIV-1 isolates from thirty-seven homosexuals were all subtype B (100%). On the other hand, 66 isolates from 94 heterosexuals were subtype B (70%) and 28 were non B subtypes (30% : 13 A, 4 C, 2 D, 8 E , 1 G). Only subtype B strains were isolated from 73 males who were infected with HIV inside Korea while 16 B and 20 non B subtype strains were isolated from 36 males who were HIV infected outside of Korea. However, B and non B strains were isolated half and half from females who were infected inside Korea except one. Conclusion : The HIV-1 subtype B strains are prevalent in Korea from the early HIV infection until present in both homo and heterosexuals. Non B strains have been transmitted from men who were infected outside Korea to their spouses and casual partners. So, we need further study to monitor subtype B and non B HIV transmission in epidemiological groups of Korea, (Korean J Infect Dis 33:311∼318, 2001)

      • SCIESCOPUSKCI등재
      • HgCdTe 제작 다이오드 어레이의 열처리에 따른 전기적 특성

        이정환,권순석,김명녕,이상래,황문구 大田産業大學校 2001 한밭대학교 논문집 Vol.18 No.-

        This paper is investigated on the study of uniformity improvement and electrical characteristics for the 1×128 diode array used Hg^0.7Cd^0.3Te. The electrical characteristics were measured for the device manufactured by several different annealing processes and temperatures being discrepant from existing method of annealing processes and temperatures. The results of uniformity were improved from 60∼80[%], the rate of existing uniformity, to 99[%]. The results obtained from analyzing and examining the characteristics of current-voltage(I-V) and capacitance-voltage(C-V) are following. First, the reverse current show 6[㎁] or so. It is seemed to be resulted from the decrease of direct tunneling and trap tunneling of the device. Second, when the input bias voltage is zero, the maximum value of reverse resistance show 12[GΩ], and the mean value of reverse resistance show 5[GΩ]. Third, it is shown that the voltage of the maximum value of resistance is shifted 0.1[V] to the reverse direction.

      • 지식 창조적 기업 지식체계 : 개념적 연구모형 A Conceptual Research Model

        이희석,최병구,장재경,홍순근 한국정보전략학회 1998 한국정보전략학회지 Vol.1 No.1

        현재 국내 경제는 그 어느 때 보다 심각한 전환기에 처해 있다. 과거 한국이 갖고 있던 장점은 우수한 노동력이었으나 이제는 더 이상 경쟁력의 원천이 될 수 없다. 남은 유일한 방법은 인적자원의 창조적 활용이다. 여기서 인적 자원은 산업사회의 단순한 노동력이 아닌 인력의 질, 즉 지식이다. 기업지식체계는 기업의 무형지적자산을 체계적으로 창출, 축적, 활용하는 기반이며 지식경영의 핵심 기술이다. 본 논문은 직식 생산이 기업 경쟁력 제고의 핵심으로 점차 그 중요성이 증대되고 있음을 주목하여 지식 창조적 기업 지식 체계를 위한 개념적 연구 모형을 제안한다. 연구모형으로 우선 기업지식 창조과정이 소개되며 창조과정별 기업지식 형태가 파악된다. 나아가서 지식 창조 및 관리를 위하여 지식마당과 기업지식체계로 구성된 기업지식 환경이 제시된다. 기업지식체계는 지식 사용자환경, 지식 마이닝, 지식활용, 지식관리 서브시스템, 지식 리파지토리로 구성된다. 제안된 지식창조과정의 현실적 타당성 예시를 위하여 국내 신상품 개발 업무가 적용되었다. 본 연구 모형은 향후 여타 지식경영 연구의 출발점으로 사용될 수 있도록 유연하게 구성되는데 중점이 주어졌다.

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