Studies on the Sfety of Korean Ginseng Ingested as Food Substance

홍순근,윤한교,장규섭,Hong, Soon Keun,Yoon, Han Kyo,Chang, Kyu Seob Institute of Agricultural Science 1984 農業技術硏究報告 Vol.11 No.2

In order to study the safety of ginseng ingested as a food substance, rats were fed ginseng added feed (subgroup 1: 0.625g/kg feed; subgroup 2: 1.25g/kg feed; subgroup 3: 2.5g/kg feed) for periods up to 6 months. Growth rates, blood composition, blood cell counts, and histopathological studies were carried out on both the control and test animals to study the effect of ingested ginseng. Following results were obtained: 1. The growth rates of the test and control animals were similar with the exception of the subgroup 3 in the 2-month fed animals who had a lower weight gain, and the subgroup 2 in the 4-month fed group who had a higher weight gain than the controls. 2. Liver, spleen, kidney, brain, lung and heart weights were similar between the test and the controls. 3. RBC, WBC, hematocrit, and hemoglobin values were similar between the test and control animals. the blood composition determination showed a similar level of alkaline phosphatase, triglyceride, total cholesterol, S-GOT, free cholesterol between the test and controls. However, free fatty acid, total lipid and S-GPT levels decreased while phospholipid, total protein, and HDL-cholesterol levels tended to increase. 4. Fl, F2 generations showed no abnormai values in blood count, organ weight and external appearance. 5. No histopathological differences were observed between the test and control animals even after a long-term administration of ginseng. However, there was evidence that ginseng promotes hematopoiesis in test animals. 6. These results suggest that ginseng is not only safe as a food substance but may indeed strengthen the body and help-prevent diseases of old age.

Constraint and Dedication based Motivations on Use Continuance for a Web Portal Site

홍순근 한국자료분석학회 2008 Journal of the Korean Data Analysis Society Vol.10 No.3

Most of the IS continuance research has assumed that IS use is activated by an intention to use, which, in turn, is determined by the evaluation of IS usage. Perceived usefulness is one of the evaluation variables most widely used. Typically, the past studies adopt this perceived usefulness because it views continuance as an extension of acceptance behavior. However, the literature on interpersonal relationships suggests that individuals are motivated to maintain relationships either because they genuinely want to or they believe they have no other option. The former is referred to as dedication-based relationship maintenance and the latter as constraint-based relationship maintenance. The IS continuance can be considered as the relationship maintenance situation with the existing IS that the user is currently using. The belief constructs previously used in IS continuance researches fall into the category of dedication-based ones. Additional constraint-based belief constructs are needed to explain the IS continuance behavior. In this regard, switching cost represents an important avenue for better understanding and predicting IS users retention in that it can be regarded as the constraint-based motivation for relationship maintenance or IS use continuance. For an empirical exploration, 275 samples were collected from the users of a web portal site. Data analysis using Structural Equation Modeling (SEM) shows that perceived usefulness shows a significant direct effect on continuance intention while perceived switching cost significantly affects continuance usage.

한우송아지의 폐사율 절감 방안

홍순근 충남대학교 농업생명과학대학 2007 논문집 Vol.- No.14

LC-MS/MS를 이용한 인체시료 중 프탈레이트 대사체 동시분석법 확립

홍순근,남혜선,정기경,강일현,김태성,조상은,정수희,이장우,김준철,고영림,강태석,Hong, Soon-Keun,Nam, Hye-Seon,Jung, Ki-Kyung,Kang, Il-Hyun,Kim, Tae-Sung,Cho, Sang-Eun,Jung, Su-Hee,Lee, Jang-Woo,Kim, Jun-Cheol,Kho, Young-Lim,Kang, Tae-Se 한국환경보건학회 2010 한국환경보건학회지 Vol.36 No.6

Phthalates, such as di (2-ethylhexyl) phthalate (DEHP), dibutyl phthalate (DBP) have been proved to be teratogenics and endocrine disruptors, metabolized rapidly and excreted in the urine. In this study, a simultaneous analytical method for 10 phthalate metabolites, MnBP, MiBP, MBzP, MCHP, MEHP, MEHHP, MEOHP, MnOP, MiNP and MiDP, in human urines, based on switching system with on-line pretreatment column using HPLC-MS/MS has been developed. This method was validated according to the guideline of bioanalytical method validation of National Institute of Toxicological Research. Limits of detection range between 0.2 and 0.9 ng/ml for 10 phthalate metabolites. The calibration curves showed linearity in the range 0.997~0.999, and the results of the intra- and inter-day validations were in the range from 0.4 to 14.7% RSD and from 0.3 to 9.4% RSD, respectively. Recoveries of phthalate metabolites varied from 87.0 to 116.1%. This analytical method showed high accuracy and stable precision for all metabolites, and seems to be suitable for biomonitoring of phthalates in human urine.

Internal and External Beliefs as the Determinants of Use Continuance for an Internet Search Site

홍순근(Soon-Geun Hong) 국제e-비즈니스학회 2010 e-비즈니스 연구 Vol.11 No.5

정보시스템 수용의 외생적 및 내재적 동기의 효과에 대한 개인적 관여도의 조절효과

홍순근(Soon-Geun Hong) 국제e-비즈니스학회 2008 e-비즈니스 연구 Vol.9 No.3

인삼 사포닌의 High Performance Liquid Chromatography에 의한 분리

홍순근(Soon Keun Hong),박은규(Eun Kyue Park),이춘영(Choon Young Lee),김명운(Myong Un Kim) 대한약학회 1979 약학회지 Vol.23 No.3,4

A high performance liquid chromatograpic procedure is described for determining ginseng saponins such as ginsenoside-Rb1, -Rb2, -Rc, -Rd, -Re, -Rf, -Rg1, and-Rg2. Ginseng saponins extracted with 90% methanol and water-saturated butanol were compared with pure standard ginsenosides. The resolution of the saponins was satisfactory and detection limit for each saponin was about 5mcg. Separation of the saponins was accomplished using a mc Bondapak carbohydrate analysis column, mobile phase of acetonitrile-water-butanol (80:20:15) and differential refractive index(RI) detector. The reproducibility and the recovery were also studied. This method was applied for determining the saponin contents of several parts of leaf, fresh ginseng, white ginseng, and red ginseng.

Studies on the Sfety of Korean Ginseng Ingested as Food Substance

Soon Keun Hong(洪淳根),Han Kyo Yoon(尹漢敎),Kyu Seob Chang(張奎燮) 충남대학교 농업과학연구소 1984 農業技術硏究報告 Vol.11 No.2

Studies on the Safety of Korean Ginseng Ingested as Food Substance

Hong, Soon Keun,Yoon, Han Kyo,Chang, Kyu Seob 충남대학교 농업과학연구소 1984 農業技術硏究報告 Vol.11 No.2

In order to study the safety of ginseng ingested as a food substance, rats were fed ginseng added feed (subgroup 1: 0.615g/kg feed; subgroup 2: 1.25g/kg feed; subgroup 3: 2.5g/kg feed) for periods up to 6 months. Growth rates, blood composition, blood cell counts, and histopathological studies were carried out on both the control and test animals to study the effect of ingested ginseng. Following results were obtained: 1. The growth rates of the test and control animals were similar with the exception of the subgroup 3 in the 2-month fed animals who had a lower weight gain, and the subgroup 2 in the 4-month fed group who had a higher weight gain than the controls. 2. Liver, spleen, kidney, brain, lung and heart weights were similar between the test and the controls. 3. RBC. WBC, hematocrit, and hemoglobin values were similar between the test and control animals. the blood composition determination showed a similar level of alkaline phosphatase, triglyceride, total cholesterol, S-GOT, free cholesterol between the test and controls. However. free fatty acid, total lipid and S-GPT levels decreased while phospholipid. total protein, and HDL-cholesterol levels tended to increase. 4. F1, F2 generations showed no abnormal values in blood count, organ weight and external appearance. 5. No histopathological differences were observed between the test and control animals even after a long-term administration of ginseng. However, there was evidence that ginseng promotes hematopoiesis in test animals. 6. These results suggest that ginseng is not only safe as a food substance but may indeed strengthen the body and help-prevent diseases of old age.

직장인의 SNS 사용 분석을 통한 SNS 기획

김은주,홍순근,황찬규,Kim, Eun-Ju,Hong, Soon-Geun,Hwang, Chan-Gyu 한국전자통신학회 2013 한국전자통신학회 논문지 Vol.8 No.9

After platform changed from PC-based internet to mobile, SNS became new interactive media which relaces face-to-face interaction. the SNS users have already begun to recognize SNS as daily necessity. SNS market has been subdivided. In other words, SNS has entered into a period of vertical SNS that focus on contents and specific target. Therefore, It is necessary to analyze users for SNS planners. For this reason, analyzing why office workers who have the most powerful purchasing power use SNS is meaningful for SNS planners. Therefore, in this study, we analyzed the reasons for using SNS of office workers by studying relationship among office workers' stress, social support, self-expression and the use of SNS. As a result, the use of SNS has a significantly positive correlation with social support and self-expression. The self-expression in the SNS is not associated with stress, but rather it is the characteristics of the office workers. However the social support in the SNS affects to stress. PC기반의 인터넷에서 모바일로 플랫폼의 변화가 일어난 후 SNS가 대면 교류를 대체하는 새로운 대화 매체로 자리를 잡았다. 사용자들은 이미 SNS를 생필품으로 인식하기 시작했으며 나아가 SNS시장은 세분화 되고 있다. 즉, 특정 대상과 컨텐츠에 집중한 수직적(Vertical) SNS의 시대로 접어들었다고 볼 수 있다. 따라서 SNS기획에서 명확한 사용자 분석이 필요하며 이러한 시점에서 가장 구매력이 있는 직장인들이 SNS사용 이유를 살펴보는 것은 SNS사업자 입장에서는 의미가 있다. 이에 본 연구에서는 'SNS사용과 자기표현 및 사회적 지지와 직장인의 스트레스와의 관계'를 살펴봄으로써 직장인의 SNS사용 이유를 분석하였다. 그 결과 SNS 사용은 자기표현 및 사회적 지지와 관련 있었다. SNS에서의 자기표현은 직장인의 특성상 스트레스와 관련이 없었으나 SNS에서의 사회적 지지는 스트레스에 영향을 미치는 것을 확인하였다.