Tabes Dorsalis의 핵자기공명영상 및 전기생리학적 소견

권기한,김성민,권석범,이병철,조광호,주정희 대한신경과학회 1999 대한신경과학회지 Vol.17 No.3

Assessment of In Vitro Assay System for Thyroid HormoneDisruptors Using Rat Pituitary GH3 Cells

Hee Jin Kim1,Hae Young Park1,Jeonga Kim1,Il Hyun Kang2,Tae Sung Kim2,Soon Young Han2,Tae Seok Kang2,Kui Lea Park2,Hyung Sik Kim1 한국독성학회 2006 Toxicological Research Vol.22 No.4

The development of in vitro assays has been recommended to screening and test-ing the potential endocrine disruptors (EDs). These assay systems focus only on identifying thethe thyroid hormone (TH) disruptors. The aim of this study was to evaluate a test system to detectTH disruptors using rat pituitary tumor GH3 cells. The test system is based on the TH-dependentincrease in growth rate. As expected, L-3,5,3-triiodothyronine (T3) markedly induced a morphologicalchange in GH 3 cells from flattened fibroblastic types to rounded or spindle-shaped types. T3 stimu-lated GH3 cell growth in a dose-dependent manner with the maximum growth-stimulating effect9 M. In addition, T3 increased the release of growth hor-mone and prolactin into the medium of the GH3 cells culture. Using this assay system, the TH-dis-rupting activities of bisphenol A (BPA) and its related compounds were examined. BPA,dimethylbisphenol A (DMBPA), and TCI-EP significantly enhanced the growth of GH3 cells in therange of 1 × 10-5M to 1 × 10-6M concentrations. In conclusion, this in vitro assay system might bestandardization before it can be used as a broad-based screening tool.

횡문근 융해증의 Tc-99m Methylene Diphosphonate 신티그라피 소견

한창진,박찬희,윤석남,배문선,김수지,신규설 아주대학교 1997 아주의학 Vol.2 No.2

Many causes of rhabdomyolysis have been reported in the literature. Technetium-99m methylene dipho-sphonate (Tc-99m MDP) bone scintigraphy is considered to be the most sensitive and effective modality in defining the extents of disease involvement and follow-up of patients with rhabdomyolysis. In this paper, we reviewed two cases of generalized rhabdomyolysis related to seizure activities and two cases of localized rhabdomyolysis related to an excessive exercise. In addition other causes of rhabdomyolysis and possible mechanisrns of Tc-99m MDP uptake are discussed briefly.

인체 방광암에서 p33^ING1의 발현 변화

이석영,신관희,한광희,이상철,김용태,김원재 大韓泌尿器科學會 2001 Korean Journal of Urology Vol.42 No.7

아래턱뼈 계측을 통한 한국인의 체질인류학적 특징 및 남녀판별함수 분석

허경석,고기석,정한성,강민규,최병영,김희진 대한췌담도연구회 2000 대한췌담도연구회지 Vol.5 No.4

커피설기의 재료 배합비에 따른 품질 특성 및 상품화 방안

서한석,김세희,한복려,황인경 한국조리과학회 2004 한국식품조리과학회지 Vol.20 No.2

The purpose of this study was to investigate the instrumental and sensory characteristics of coffee-sulgi(rice cake) with different ratios of the ingredients; coffee(30㎖, 40㎖ and 50㎖ of espresso and instant coffee) and sugar(50g and 75g). A commercial scheme for coffee-sulgi was also investigated. The optimal mixing ratios of coffee-sulgi with added espresso were rice flour 500g, salt 5g, espresso 40㎖ and sugar 75g. Those of coffee-sulgi with added instant coffee were the same. As the sensory intensities of coffee aroma, coffee taste, sweetness, moistness, elasticity, color acceptance for coffee-sulgi and overall acceptance for quality were enhanced, the overall preference for coffee-sulgi was increased. In addition, overall preference was positively correlated with adhesiveness and a-value of instrumental characteristics, but negatively correlated with cohesiveness and L-value. In coffee-sulgi with added espresso, intensities of coffee aroma, browniness, coffee taste, color acceptance for coffee-sulgi, overall acceptance for quality and overall preference were higher than those of coffee-sulgi with added instant coffee. In this point, gourmet coffee-sulgi with added espresso and universal coffee-sulgi with added instant coffee could be differentiated in the coffee-sulgi markets. In conclusion, this study of coffee-sulgi and the differential scheme for the market will be useful to expand rice processing, enhance the intake of rice cakes and provide a reference for commercialization of rice cakes.

장기입원환자 관리 방해요인

이경석,윤석만,권희,이호,김혜경,조미자,한규남,김명성 순천향의학연구소 2003 Journal of Soonchunhyang Medical Science Vol.9 No.1

Background: Recently the health insurance review agency tried to cut off the cost of unnecessary hospital stay. It is important to reduce the prolonged occupation of the hospital beds. However, there are some obstacles of the management for the prolonged bed occupation. We report our experiences and the problems of bed-control. Methods: To increase the rate of effective bed-usage, a task force was made. This team was consisted of 4 dctors, 2 nurses and 2 personnel of the administrative department. From December 20th 2001 to May 17th 2002, the task force analysed the rate, number and causes of the prolonged (more than 60 days, regardless of the disease entities) bed occupation. We announced and explained the necessity of bed-control and actively pressed to reduce the prolonged bed occupation. Results: The number of the prolonged bed occupation was 71 at the beginning of the management. It was reduced to 46 at best, then turned back to 65 at the end. It seems to be impossible to reduce the prolonged bed occupation until there are sufficient numbers of long-term care facilities. Aggressive bed control makes the sick patients to move every two or three months, it is never desirable. Conclusion: We cannot expect any Quality Improvements without improvement of the wrong system. Prior to the management for the prolonged bed occupation, it is necessary to build a sufficient number of long-term care facilities.

차체 점용접 접합부 피로강도의 실험해석

김정한,유희,염영진,주영우,주석재 울산대학교 1999 공학연구논문집 Vol.30 No.1

다양한 외부 동하중에 의한 피로파단이 발생하고 있는 승용차 차체 점용접 접합부에 대해 피로시험을 수행함으로써 전반적이 피로거동을 파악하고자 하였다. 실제 파단 발생 부재를 구성하는 차체재료중 SPCC, SPRC35, SAPH38P를 선택하여 용접조건, 동종 및 이종재료간의 접합, 두께 조합을 가급적 실차와 동일하게 적용하여 다양한 인장-전단 및 십자-인장 점용접 시편을 제작하였다. 그리고 정적시험 및 피로시험을 수행하여 강도 데이터베이스를 구축하였다. The fatigue behaviour of spot-welded joints of a car body, in which fatigue fracture occurs by various external dynamic loads, is characterized by performing fatigue tests. SPCC, SPRC35, and SAPH38P steels are selected which constitute the car body. Welding conditions and combinations of steels and thicknesses are chosen to reproduce those of a real car body and various tensile-shear and cross-tension spot-welded specimens are manufactured. Both static tests and fatigue tests are carried out, and the database of spot-weld strength is constructed.

Box-Jenkins法을 利用한 河川水質의 時系列 豫測

趙廷錫,韓陽洙,金喜洛 大邱大學校 科學技術硏究所 1997 科學技術硏究 Vol.4 No.2

This study was carried out to develop the stochastic stream water quality model for the intaking station of Taejoun City waterworks in the Keum River system. The monthly water dissolved oxygen with periodicity and trend were forcasted by multiplicative ARIMA models and then the applicability of the models was tested based on 13years of the historical monthly water quality data at Taejoun City intaking site. The parameter estimation was made with the monthly observed data. The last one year data was used to compare the forcasted water quality by ARIMA model with the observed. The models are ARIMA(2.0.2)x(2.1.1)_(12) for dissolved oxygen. The forecasting results showed a good agreement with the observed. It is implying the applicability of multiplicative ARIMA model for forecasting monthly water quality at the Taechoung site.

열공형과 비열공형 피질하 혈관성 치매에서 위험인자의 차이에 관한 비교 연구

배희준,정지향,유경호,나덕렬,김상윤,최경규,양동원,손의주,이상도,김재우,박경원,김응규,이재홍,박미영,한일우,함동석,최문성,하충건,최성혜,이애영,이병철,한설희 대한치매학회 2003 Dementia and Neurocognitive Disorders Vol.2 No.2

Backgrounds and Objectives: Vascular dementia is a group of dementing disoders arising from various stroke syndrome. Among these. subcortical ischemic vascular dementia (SIVD) is regarded as a relatively distinct clinical entity. However, MRI patterns of SIVD are not homogenous. In some patients, lacunes are dominant, and in others, subcortical white matter changes are. This study was designed to compare risk factor profiles between SIVD with and without multiple lacunes. Methods: We divided 47 subjects (22 males, mean age. 68 years) recruited from VADAPET (Multicenter Trial For Evaluation Of The Changes In the PET Images Of Subcortical Vascular Dementia Patient) study into two groups one with more than 5 lacunes in deep gray matter (lacune group) and the other with 5 or less(non-lacune group) Clinical characteristics and laboratory findings of two groups were compared. Results: Nineteen of 47 patients (40%) belonged to the lacune group. The lacune and non-lacune groups d d not differ in the following variables: age, hypertension, diabetes mellitus, hyperlipidemia heart disease, history of stroke or TIA, history of trauma or major surgery, family history of hypertension stroke, or dementia, age at diagnosis of dementia, body mass index, white blood cell count, ESR, CRP, fibrinogen, hemoglobin A1C, total cholesterol. LDL cholesterol creatinine, proteinuria, glucosuria, and microhematuria. However, male sex, smoking alcohol. hemoglobin, and HDL cholesterol were possibly associated more with lacune group SIVD than with non-lacune group (p<0 1) Multivariate analyses revealed that smoking, hemoglobin, and HDL cholesterol were independent predictors of SIVD with multiple lacunes Conclusion: Our study suggests that SIVD with multiple lacunes may be significantly different in smoking habits hemoglobin, and HDL cholesterol from SIVD without multiple lacunes.