Methexymethyl sulfide를 이용한 합성연구

김정순,고영관,김대광,윤세중 공주대학교 기초과학연구소 1992 論文集 Vol.30 No.1

For the preparation of broad range of substituted aryl derivatives from the bromophenyl methoxymethyl sulfide and the bromobenzyl methoxymethyl sulfide, various functional groups such as alkyl, ester and haloketone could be easily introduced in the aromatic methoxymethyl sulfides by treatment with various electrophiles. Substituted methoxymethyl phenyl sulfides were converted to the arenesulfonyl chlorides with chlorine in water-dichloromethane at 5∼10℃. And substituted benzyl methoxymethyl sulfides were also converted to the arylmethanesulfonyl chlorides with N-chlorosuccinimide in aqueous acetic acid, at 5∼10℃.

FEM을 이용한 선삭가공 절삭조건의 영향 분석

임세환,송춘삼,홍석관,강정진,김주현 한국공작기계학회 2007 한국공작기계학회 추계학술대회논문집 Vol.2007 No.-

A plane strain finite element model is developed to simulate turning with continuous chip formation using adaptive remeshing during the thermal-mechanical coupled analysis. Comparisons between the experimental and simulation results for cutting forces are performed to validate FE analysis results. Influences of machining parameters such as depth of cut, cutting speed and feed rate on cuting force and shear angle are analyzed by Taguchi method. The more depth of cut and feed rate result in the increase of cutting forces, but the rates of increase are decrease due to the larger shear angle. As the cutting speed increases, von Mises stress of workpiece near the tool tip decreases because the strength of specimen decreases at high temperature above 500℃. This thermal effect on cutting force is negligible because the affected area is very localized and the average values of von Mises stress in the shear plane are the same among the diverse cutting parameters.

뇌경색후 발생한 Cortical Spreading Depression과 뇌경색 범위에 관한 실험적 연구

박윤관,이승민,김세훈,이기찬,주정화,이훈갑 대한신경외과학회 1996 Journal of Korean neurosurgical society Vol.25 No.3

Cortical Spreading Depression(CSD) is a transient depression of neuronal activity that spreads across the cortical surface and is associated with profound changes in blood flow, extracellular ion concentration. Direct Current(DC) potentials and cell membrane potentials. One of the electrophysiological disturbance in the periinfarct surrounding is spontaneous occurrence of repeated CSD like DC shifts associated with increased energy demand. Due to restricted blood flow to the periinfarct border zone, elevated metabolic demand is potentially harzardous. So the authors designed this experiment to verify the correlation between periinfarct cortical spreading depression and ischemic volume following permanent middle cerebral artery (MCA) occlusion in rats. Sprague-Dawley rats(n=27) were anesthetized with 0.5∼1% halothane, and artificially ventilated through a tracheal cannula. Arterial pressure, blood gases and body temperature were controlled. The middle cerebral artery(MCA) was occluded distally to the lenticulostriate branches. Measurements of CSD activity were made for 4 hours in each animal. Infarct volume was determined 6 hours later in 2, 3, 5-triphenyl tetrazolium chloride(TTC)-stained sections. For 4 hours after MCA occlusion, the CSDs were found in all experimental animals with a range of 2∼9 times. Those CSDs wer of varying duration, : "small"(<1 min) and "big"(> 1 min) SDs and mean of total duration of SD was 10.5±10.3 min during 4 hours of MCA occlusion. Neuropathological evaluation of brain infarct in the rats, which had been allowed to survive for 6 hours after MCA occlusion showed a mean volume of 89.7±45.3㎣. Serial observation of duration of CSD showed progressive prolongation only in 8 rats. The rest of them(n=19) did not show any prolongation. Neither the prolongation of duration of CSD nor the frequency of CSD in the penumbral zone correlated with the volume of infarct. However total duration of CSD was slightly related with the infarct volume after 6 hours of the permanent MCA occlusion(r=0.414, p=0.0318).

Phanerochaete chrysosporium의 액체 배양 및 Lignin Peroxidase 생산

박세근,정명선,김영관 江原大學校 産業技術硏究所 2001 産業技術硏究 Vol.21 No.A

This study characterizes the growth of white rot fungi Phanerochaete chrysosporium IFO 31249 and lignin peroxidase(LiP) activity in different submerged culture media. P. chrysosporium was grown in the form of pellet of various sizes from a spore inoculum under shaking liquid culture condition. While the growth of mycelia was higher under the nitrogen-sufficient culture than under the nitrogen-limited culture, ligninase activity was relatively lower. The lignin peroxidase appeared in nitrogen-limited culture and was suppressed by excess nitrogen. High level(40U/l) of lignin peroxidase activity was obtained in the growth medium containing 1.5mM veratryl alcohol, a secondary metabolite of P. chrysosporium. Lignin peroxidase production was not observed under conditions of nitrogen sufficiency or in balanced media, suggesting that control parameters could increase the activity by manipulating the secondary metabolism.

順天地域의 삼설양굿 調査硏究

崔德源,鄭漢基,任成來,奇世官 順天大學校 1983 論文集 人文社會科學篇 Vol.2 No.-

We can say Shamanism is the Korean religious Phenominon from ancient times. In addition, foreign religions had been brought in Korea and they had intermixed on the substructure of shamanism and then a new folk religion has been formed. We, human beings, who have blessed that we remove evil, call happiness, treat a desease, invoke a good harvest, invoke having a son and the dead enter into paradise from old times, have been relied upon the ritual of shamanism for our existential problem, but the Mu-dang(Gut: which is a ritual performed by a shaman) of traditional folk customs is now gradually going out of sight and even the historical meaning and function are becoming forgotten. In Chonnam district, Sam-sol-yang Gut in which a shaman puts on a mask like a ghost-face, sings and performs a dramatic Gut(or, a dramatic ritual), was widely prevalent, but it is difficult to see the unique Mu-gut(or, shamanistic ritual) in these days. By good luck have we found that Sam-sol-yang Gut remaining only in Sunchon district is being performed by a hereditary shaman. This is the shaman who has been inherited since six generations and has a Dang-Gol Pan in Sunchon district. Sam-sol-yang Gut is a hereditary shaman song type and a Mu-gut which prays for the healing of a mental patient by the help of god. We think this Gut becomes good data in examining the shamanistic religions and its chant and the story about god are the works which drives away devils and have a lyric structure. The purpose of this paper is to supply the classical literature and the folklore and the like with several shamanistic data and is to study the interpretation of the shaman song, its rhythm and the structure of the ritual and the god's response and peculiarity of the Mu-gut so as to examine the original thoughts and trace the meaning to its origin as we should have carried into the fieldwork of Sam-sol-yang Gut. And also the result of this study is very helpful to the ontological interpretation of Korean shamanism and in addition is more meaningful in arranging the transmissive data which are going away.

강직성 슬관절에서의 슬관절 전치환술

조우신,박종희,김정민,오세관 대한슬관절학회 2003 대한슬관절학회지 Vol.15 No.1

목적: 강직이 동반된 슬관절염 환자에서 슬관절 전치활술의 문제점, 결과 및 합병증을 분석하고자 하였다. 대상 및 방법: 1994년 1월부터 2000년 12월까지 슬관절 강직(운동 범위 50도이하)이 있는 환자에게 슬관절 전치환술을 시행하여 2년 이상 추시가 가능하였던 16례를 대상으로 하였다. 수술은 관절 강직이 발생한지 평균 12.2년(1~40년)에 시행하였으며, 추시기간은 평균 3.3년(2~6년)이었다. 16례 중 남자 3례, 여자 13례였고, 평균 나이는 55.8세(34세~75세)였다. 감염에 의한 후유증 6례로 가장 많았고 그 외 퇴행성 관절염 4례, 외상 후 관절염 3례, 류마티스성 관절염 3례의 순이었다. 술 후 평가는 추시기간 중의 운동 범위와 HSS score 및 합병증을 분석하였다. 결과: 관절 운동 범위는 술 전 평균 31.6도(0~50도)에서 추시시 평균 95.4도(80~120도)로 증가하였으며, 1례에서만 5도의 굴곡 구축이 있었다. HSS score는 술 전 평균 59.6점(43~76점)에서 추시시 평균 84.6점(76~92점)으로 향상되었다. 1례에서 수술 중 슬개건 부분파열이 있었으나 보조기 착용과 적극적 재활로 술 후 1년째 90°의 관절 운동이 가능했다. 표재성 감염 1례는 창상의 변연절제술 후 피부이식으로 치유되었고, 심부 감염된 3례는 추후 관절 유합술을 시행하였다. 결론: 슬관절 전지환슬은 강직된 슬관절의 기능을 회복시킬 수 있는 좋은 술기이지만 감염등의 합병증을 고려해서 시행되어야 한다. Purpose: To evlauate the results of TKRA (Total knee replacement arthroplasty) for the treatment of stiff knee. Methods & Materials : TRKA has been performed for 18 cases of stiff knee ( ROM < 50° ) between January 1994 and December 2000. 16 cases which have been followed up for more than 2 years were analysed. Average follow-up was 3.3 years(2~6 years). 3 were male and 13 female. The average age was 55.8 years(34~75 years). Sequales of infection were most with 6 cases and followed by osteoarthritis (4 cases, 2 cases had been performed arthroscopic debridement) and rheumatoid arthritis (3 cases) and traumatic arthritis (3 cases) in order. TKRA was performed on average 12.2 years (1~40 years) after knee stiffness has been developed. We evaluate the results with ROM, HSS score and complications. Results : Average ROM was increased from 31.6°(0°~50°) preoperatively to 95.4°(80°~120°) postoperatively. 5° of flexion contracture was present in only 1 cases. Average HSS score was improved from 59.6 points preoperatively to 84.6 points postoperatively. The patella tendon was partially ruptured in 1 case surgery, but by brace application and rehabilitative exercise, ROM was improved to 90°, 1 year post operatively. There were 1 superficial skin infection which was resolved by revision of wound and skin graft, and deep infection in 3 cases, which needed knee fusion finally. Conclusion : TKRA is a good method for improving function in knee stiffness although infection risk is high.

경주지역 여고생의 초경과 체성장간의 관계

김준섭,권오구,박진석,오종수,박정현,박제식,안세한,이용환,서정호,신태섭,최영배,김덕수,이관,박수경 東國大學校醫學硏究所 2002 東國醫學 Vol.9 No.1

본 연구는 경주지역 1개 고등학교 3학년 여고생을 대상으로 초경 시작 전인 초등학교 4학년부터 고등학교 2학년까지의 키, 몸무게, 가슴둘레 수치와 초경 연령을 파악하여 여성의 초경이 빠를수록 체성장 속도의 변화가 있을 것이라는 가설을 기초로 두 요인간의 관련성을 파악하고자 시행되었다. 경주시 1개 여자고등학교 3학년생 총 317명에 대해 ㅊ경 나이, 초경시 심리 상태, 초경이 시작되었을 때의 상담 여부와 상담하였던 사람, 부모 신장과 초경전후의 식사 규칙성, 다이어트 경험, 수면시간, 스트레스, 음주/흡연 여부, 질병력 등에 대한 설문 조사를 시행하였고, 초등학교 4학년부터 고등학교 2학년까지의 키, 몸무게, 가슴둘레에 대한 정보는 건강기록부에서 확보하였다. 상기 대상자 중 건강기록부가 분실된 39명, 초경나이에 대해 응답하지 않았던 29명 및 결석 등으로 조사를 하지 못하였던 42명을 제외한 조사 대상자는 206명으로 선정하였다. 대상자들의 초경연령 평균값(Mean±SD)은 13.0±1.11이었고, 초등학교 4학년부터 고등학교 2학년까지의 초경 이후 신장 성장률은 감소하였으며, 초경연령이 빠른 군이 초등학교 때는 신장에 있어서 우위를 차지하나 고등학교에 오면서 신장은 비슷한 수준이 되었다. 초경후 1-2년 사이에 체중과 흉위의 증가율은 감소하였고, 초경연령이 빠른 군이 초등학교와 고등학교 사이에 체중과 흉위에서 모두 우위를 차지하였다. 본 연구의 결과는, 흔히 이차 성징의 시작 시점 혹은 사춘기의 시작 시점으로 보고있는 초경 연령이 청소년기의 성장과 밀접한 관련성이 있고, 특히 체중과 흉위의 성장 속도와 밀접한 관련성이 있음을 시사한다. To understand the onset of menarche in relation to changes in physical growth that take place during female adolescence, especially the changes in height and weight velocity. The 207 senior in one women high school of Kyongju were investigated in April 3 to 8, 2001. We collected the information, relation in the age at menarche, height & weight of parents, regularity of eating, and obesity diet, duration of sleeping, sickness & stress near age at menarche, by self-recording. The status of height, weight & chest circumference between the 4th grade of primary school and the junior of high school was collected by individual Health Record. The results were followed; The average age at menarche was 12.95±1.11 years old and the most frequent age of menarche is 13 years. After menarche, the velocity of height, weight and chest circumference were decreased. The most rapid group of menarche hold dominant position in height during elementary school. As time passed, they dont hold dominant position in height. The most rapid group of menarche get an advantage in the weight and the girth of chest after elementary school. The height of subjects is directly proportional to the height of their parents. These results suggest that the starting age at menestuation can be closely associated with physical growth and development.

Prevalence and characterization of infectious disease in wild birds from the South Korea

Se Yeoun Cha,Min Kang,Bai Wei,Woo seog Jeong,Yong Myung Kang,Hong Sik Park,Hyung Kwan Jang 대한수의학회 2016 대한수의학회 학술대회발표집 Vol.2016 No.-

Agrobacterium-mediated Transformation of ‘Jinkyul’ Mandarin

Kwan Jeong Song,Se Rim Kim,Saes Byel Kim,Seong Cheol Lee,Hee Beom Yang,Sun Young Ahn 한국원예학회 2006 한국원예학회 기타간행물 Vol.- No.-

반복된 확률화 응답모형에서의 독립성과 조건부 독립성 검정

이관제,국세정 한국보건통계학회 2000 보건정보통계학회지 Vol.25 No.1

Krishnamoorphy and Raghavargo(1993) invented exact binomial and asymptotically normal test procedures for truthful answering in the repeated randomized response models under the assumption that two repeated response measures are independent. Under the same assumption, Lakshmi and Raghavargo(1992) suggested asymptotic chi-square test for respondents' truthful answering in the same models. Meanwhile, Lee(1999) suggested asymptotic test for detecting consistent answering in the repeated randomized models without the assumption of independence between two repeated response variables. In this article we numerically detect the factors and the conditions of them, with which two response variables might be independent. And we find a weaker condition under which the test procedures suggested by Krishnamoorphy and Raghavarao(1993) can be applicable. That is, under the assumption of conditional independence between two response variables rather than that of independence we have the exactly same joint probability distribution of two variables and the same test statistics therein. Hence we can apply the same logical statements on deriving the tests for truthful answering in the repeated randomized response models as in Krishnamoorphy and Raghavarao(1993). Both chi-square test and Cochran-Mantel-Haeszel test are used to test independence and conditional independence between two respondence variables, respectively.