한약찌꺼기 급여가 비육돈의 생산형질 및 도체품질에 미치는 영향

이정일,송영민,박구부,박태선,진상근,주선태 한국축산학회 1999 한국축산학회지 Vol.41 No.3

This study was conducted to investigate the effect of the medicinal herb residue on growth performance, carcass quality and production cost employing 120 Landrace-Yorkshire x Duroc cross-bred gilts and boars. The medicinal herb residue was added to a commercial finishing diet(CONT) at a 3% level(TRT) and the animals were fed for 30 days either CONT or TRT diet beginning from either 58.50∼61.47㎏(finishing phase I) or 83.58∼89.94㎏(finishing phase II), 10 heads in each sex per treatment, were slaughtered. For meat quality evaluation. loin eye sections were removed for determination of cholesterol content and fatty acid compositions. 1. ADG was not affected by the dietary treatment in either gills or boars during phase I. During phase II, ADG was lesser in TRT compared with CONT, but the overall ADG for phases I plus II was not different between CONT and TRT. Feed/gain was reduced by the TRT feeding during phase I but was increased during phase Il, which resulted in a decrease in overall feed efficiency. 2. Backfat thickness was not different between the two dietary groups or sexes. Preliminary carcass grade was better in CONT than in TRT, but final grade was not different between CONT and TRT. Dressing percentage was increased by the dietary TRT treatment; among the four dietary treatment x sex groups, TRT gills showed the greatest percentage. 3. Cholesterol content in the blood was decreased by the TRT feeding. HDL and AI. which were not different between CONT and TRT. CONT gilts had the highest cholesterol and HDL content and AI value. 4. Blood leukocytes(WBC) and hemoglobin(Hb) were increased by the dietary TRT, but the reverse was true for eosinophils(EOS). TRT gilts had the lowest erythrocytes(RBC), WBC, Hb and hematocrit and the greatest EOS. 5. Cholesterol content in the loin eye section was decreased by the dietary treatment. During 45 days of storage it decreased progressively in both CONT and TRT. UFA/ Total, MUFA / Total and UFA / SFA, which were not different between CONT and TRT, increased progressively during storage in CONT, but this trend was not apparent in TRT. The above results indicate that the medicinal herb supplementation can increase weight gain during early finishing phase. However, with extended usage of it up to marketing, it can adversely affect weight gain although it improves both carcass and meat quality.

1987년 한국에서 발생한 렙토스피라병의 혈청역학적 조사

이증훈,박영수,이우곤,김석용,정선식,우준희,박성광,박경희,송영욱,김선영,기정일,최두혁,강성귀,김주완,최강원,김우열,최명식,최인학,장우현,윤성열 대한감염학회 1988 감염 Vol.20 No.3

Human leptospirosis was an unfamiliar disease in Korea until 1984 that outbreak of leptospirosis occurred among farmers and soldiers after field works for harvesting rice. During that time, Lee and Jo confirmed the first Korean cases of leptospirosis by serological test, isolation of causative agent and autopy findings. Afterward several outbreaks occurred also during autumn especially after flood in every years and some characterisitcs of leptospirosis in Korea such as clinical manifestations, serotypes and seroepidemiological features has been revealed by many investigators. Because of the major mode of transmission between rodents and human is by direct contact with leptospiral urine of rodents or contaminated soil by the urine, leptospirosis in Korea has been primarily a disease of person in occupations heavily exposed to contaminated soil or infected urine such as farmer, army and etc. Therefore it seems that leptospirosis is one of the main communicable diseases to be controlled urgently in Korea, for an agricultural people account for almost half of total Korean people. For clarifying the seroepidemiological patterns of human leptospirosis in Korea by sex, month region and main reacting serovars of L. interrogans among acute febrile disease occurred in 1987, 1,773 patient's sers with acute febrile episodes were tested by microagglutination test using 19 representative strains of leptospiral serogroup as antigen. All of those sera were collected from 10 collaborative clinics located in Kyunggi, Kangwon, Chungbuk, Chungnam, Chonbuk, Chonnam province and Seoul. The results wee summerized as follows. 1) Among 1,773 sera of patients with acute febrile episodes, 219 (12.4%) were seropositive to L. interrogans, 487(27.5%) to R. tsutsugamushi, 241(13.6%) to R.typhi and 160(90.0%) to Hantaan virus. 2) Among seropositives to L.interrogans, the male outnumbered the female, 65% and 35%. 3) For age distribution, 26.9% of seropositives to L.interrogans were fifties, 19.6% were forties, 9.1% were sixties, 5.9% were thirties and 4.1% were twenties. 4) Eighty three percent of seropositives had occurred between September and October in 1987 with a peak in September. 5) Main leptospiral serovars reactive to patient's sera were Icterohaemorrhagiae(54.3%), Canicola(31.0%), CH-48(13.2%), Tarassovi(0.9%)and Cynopteri(0.5%). 6) For regional distribution, 65.8% of seropositives to L.interrogans were residents from Chonbuk, 12.3% were Chonnam, 7.3% were Chungnam, 5.5% were Kyunggi and 1.4% were Kangwon.

Evaluation on current-limiting performance of the YBCO thin-film wire considering electric coupling condition

Du, H.I.,Han, B.S.,Kim, Y.J.,Lee, D.H.,Song, S.S.,Han, T.H.,Han, S.C. North-Holland 2011 Physica. C, Superconductivity Vol.471 No.21

The basic way to improve the performance of a superconducting current limiter is to apply and evaluate a superconducting device that is appropriate to the superconducting current limiter. Among the many types of superconducting devices, the YBCO thin film wire has excellent current-limiting performance that is appropriate for actual system application. For the application of the YBCO thin film wire to superconducting current limiters, its current-limiting performance as a unit device must be accurately evaluated, and measures to improve its current-limiting performance must be sought. Accordingly, to evaluate the current-limiting performance of the YBCO thin film wire, this study was conducted to evaluate its resistance-increasing trend, V<SUB>max</SUB>, T<SUB>r</SUB>, I<SUB>max</SUB>, I<SUB>qt</SUB>, and current-limiting rate as a unit device, after which the electric coupling condition that consists of a core and windings was used to evaluate the current-limiting performance of the YBCO thin film wire.

200 GeV/핵자 유황이온과 핵건판핵의 충돌에 의해 생성된 헬륨 파쇄핵의 극한파쇄 연구

김동철,송진섭,윤천실,정성헌,박인곤,김종오,김철수,김태연,이승희,조재희,천병구,김재률,김준원,김태익,박명렬,장한일,임인택 慶尙大學校 기초과학연구소 1992 基礎科學硏究所報 Vol.8 No.-

고에너지 중이온 원자핵과 핵건판의 충돌에서, 200GeV/핵자 유황이온에 의해 생성된 파쇄 헬륨핵(Z=2)의 실험실계의 방출각 분포는 표적핵에 무관한 회귀공식. dN=exp[a+k exp(η-y_b)]d[exp(η-y_b)]로 잘 표현된다. 여기에서 의사신속도 η=-ln[tan(θ/2)]이고, y_b는 실험실계의 입사입자(^32S)의 신속도이다. 이 공식에 의한 적합에서 k=-0.057±0.008로 얻어진다. 즉, 핵건판과 고에너지 중이온의 충돌에서 파쇄 헬륨핵의 exp(η-y_b)의 분포는 "극한파쇄" 현상을 잘 설명하고 있다. The angular distribution of emission angle θ of helium (Z=2) produced in the collisions of incident particles of 200 GeV/nucleon ^32S in nuclear emulsion is well expressed by dN=exp[a+k exp(η-y_b)]d[exp(η-y_b)] where the pseudorapidity is η=-ln[tan(θ/2)], the laboratory system primary rapidity is y_b, and k=-0.057+0.008. The shape of this frequency of occurrence distributions in terms of exp(η-y_b) attests to the validity of the concept of "limiting fragmentation" for helium projectile fragments produced in the projectile fragmentation regions of heavy ion collisions in nuclear emulsion.

대학생의 인터넷중독 및 스마트폰 중독 정도와 미술 치료 인식에 대한 조사 연구

박혜원,송승윤,윤하영,이경현,이소영,이지원,진예은,최시온,허은서,황다빈,신주현,이인영 이화여자대학교 간호학회 2018 이화간호학회지 Vol.- No.52

Purpose: Investigate the level of Internet and smart phone addiction of college students and difference of their perception on the art therapy. Method: Data was collected using 4 categories of questionnaires. Participants of this study were 383 college students who are currently attending universities located in seoul, Kyung-Ki and Incheon. The Chi-square test, One-way Analysis of Variance, Scheffé test were performed using IBM SPSS Statistics 23.0 Result: First, the study has established that the status of attending universities, grade, people who living with, age affected the level of Internet addiction of college students. In terms of the level of smart phone addiction of college students, the status of attending universities, gender, age were the affective factors. Second, there was a significant difference on the perception of the advantages of the art therapy and the level of acknowledging it, depending on the level of Internet addiction. Finally, depending on the level of smartphone addiction, there was a significant difference in the level of perception of the art therapy, expectation toward the art therapy and the helpfulness of art therapy. The more the participants are close to the addicted level, the more they want to experience the art therapy. Conclusion: These results suggest. First, it is necessary to use bigger group of participants. Second, it is necessary to improve the research methods for college students. Third, nurse should offer holistic care toward the patients regarding their general characteristics by adapting this study. Finally, it is necessary to improve the art therapy programs for the college students who are addicted to the Internet and smartphone and to develop researches proving the effectiveness of these programs.

성장월령에 따른 비거세 한우의 도체특성과 육질변화

김내수,원유석,송만강,최양일,정정수,이창림,정재경,임진희 한국축산학회 1999 한국축산학회지 Vol.41 No.6

The current study was undertaken to determine the effects of growing age on the carcass, meat quality and muscle fiber characteristics in Hanwoo bulls during the growing period of 6 to 30 months. A total of 54 heads of Hanwoo bulls (6 heads of 6 months, 12 heads each of 14, 18, 24 and 30 months) were conventionally slaughtered at each age, and then chilled overnight. The carcass characteristics and quality or yield grade (QG or YG) were determined on those carcasses, longissimus muscle (3Kg) was removed from left sides at 1st to 5th lumbar vertebrate and meat qualities or muscle fiber characteristics were evaluated. In the carcass characteristics of Hanwoo bulls, live weight, carcass weight and ribeye area except backfat thickness and dressing percent were increased(P $lt; 0.05) until 24 months of age. The backfat thickness was increased(P $lt; 0.05) from 18 to 24 months of age. The dressing percent was decreased(P $lt; 0.05) from 6 to 14 months, but thereafter slowly increased. Carcasses from 6 or 14 months of age showed A grade of YG, but carcasses from 18 to 30 months showed B grade. In QG, carcasses from 6 or 14 months showed `out of grade' and carcasses from 18 to 30 months showed grade 3 of QG, but the QG was not improved after the 24 months of age. In meat qualities of longissimus muscle, the pH and water-holding capacity tended to be similar except 18 months of age, and the meat color changed to red from 14 to 18 months of age. The shear force was increased(P $lt; 0.05) from 14 to 18 months, but after that decreased(P $lt; 0.05) at 30 months. In proximal analysis, the moisture content was decreased until 24 months of age, but the protein and fat contents tended to increase. In panel test, the flavor score tended to increase but the tenderness or total acceptability score tended to decrease until 30 months of age. In the muscle fiber characteristics, the ratio of white muscle fiber(IIW type) was the largest, and the ratio of intermediate muscle fiber(IIR type) was the smallest except for 6 or 24 months. The ratio of red muscle fiber(IR type) or IIR type tended to decrease, but the ratio of IIW tended to increase until 24 months of age. In the muscle fiber diameter, the IIW type had the largest diameter, but the IR type had the smallest diameter except the I8 or 24 months of age. The diameter of three muscle fiber types tended to increase until 30 months, and the IIW type showed faster increase. In the transmission electron micrographs, muscle fiber from longissimus muscle of 6 months did not show the full development and the A or I band was not fully observed. However, muscle fiber from longissimus muscle of 18 months showed thicker Z-line and the A or I band was fully observed. The longissimus muscle of 24 or 30 months showed the similar morphological pattern of muscle fiber as 18 months of growing age, but the muscle fiber seemed to be fully developed.

The effects of combined dietary probiotics Lactococcus lactis BFE920 and Lactobacillus plantarum FGL0001 on innate immunity and disease resistance in olive flounder (Paralichthys olivaceus)

Beck, B.R.,Kim, D.,Jeon, J.,Lee, S.M.,Kim, H.K.,Kim, O.J.,Lee, J.I.,Suh, B.S.,Do, H.K.,Lee, K.H.,Holzapfel, W.H.,Hwang, J.Y.,Kwon, M.G.,Song, S.K. Academic Press 2015 FISH AND SHELLFISH IMMUNOLOGY Vol.42 No.1

<P>The effects of a dietary probiotic mixture containing Lactococcus (Lc.) lactis BFE920 isolated from bean sprout and autochthonous Lactobacillus (Lb.) plantarum FGL0001 originally isolated from the hindgut of olive flounder (Paralichthys olivaceus) were investigated for the purpose of improving the probiotic effects of Lc. lactis BFE920 on the olive flounder. The immunostimulatory, disease protective, and weight gain effects of Lc. lactis BFE920 were significantly improved when olive flounder (average weight 37.5 +/- 1.26 g) were fed the probiotic mixture (log(10) 7.0 CFU each/g feed pellet) for 30 days. Flounder fed the mixture showed improved skin mucus lysozyme activity and phagocytic activity of innate immune cells compared to flounder fed a single probiotic agent or a control diet. While the levels of neutrophil activity in flounder fed the single probiotic agent or the mixture were similar, they were significantly higher than levels in a control group. Additionally, probiotic-fed flounder showed significantly increased expressions of IL-6, IL-8, and TNF-alpha in the intestine compared to the control group. Following a 30-day period of being fed probiotics or a control diet, the olive flounder were challenged with an i.p. injection of Streptococcus iniae (log(10) 6.0 CFU/fish). The groups fed the mixed probiotics, Lc. lactis BFE920, Lb. plantarum FGL0001, and the control diet had survival rates of 55%, 45%, 35%, and 20%, respectively. Flounder fed the probiotic mixture gained 38.1 +/- 2.8% more body weight compared to flounder fed the control diet during the 30-day study period. These data strongly suggest that a mixture of Lc. lactis BFE920 and Lb. plantarum FGL0001 may serve as an immunostimulating feed additive useful for disease protection in the fish farming industry. (C) 2014 Elsevier Ltd. All rights reserved.</P>

1.88A GeV ^56Fe 중이온에 의해 원자핵건판 내에서 회절들뜸 및 준회절들뜸 기구로 생긴 다중발생

김종오,김태연,천병구,박인곤,송진섭,윤천실,박상렬,이경언,김재률,김태익,박명렬,임인택,장한일,박복남 慶尙大學校 기초과학연구소 1990 基礎科學硏究所報 Vol.6 No.-

원자핵건판 내에서 1.88A GeV의 에너지를 갖는 ^56Fe 중이온(heavy ion)의 평균자유행로는 비적추적법(along-the-track scanning method)을 사용하여 8.01±0.27㎝로 측정되었다. ^56Fe 주이온에 의한 회절들뜸반응을 KHP 판정법으로 찾아내었으며, 회절들뜸반응에 대한 평균자유행로는 0.86±0.10m로 측정되었다. 입사중이온의 정지계 내에서 ^56Fe 중이온에 의한 80개의 회절들뜸 및 준회절들뜸반응에 대한 알파입자와 단일하전 입자의 의사신속도 분포는 각각 (γ_a-η_b)_max=3.31, (γ_a-η_b)_max=2.30에서 최대값을 갖는 가우스분포함수 형태를 이루었다. By employing the method of along-the -track scanning. the mean free path of inelastic collisions for 1.8A GeV^56Fe heavy ion in nuclear emulsion is measured to be 8.01±0.27㎝. "Diffractive Excitation" events are identified by using the KHP method and the mean free path of diffractive excitation is measured to be 0.86±0.10m. The distributions of pseudorapidities of alpha and singly-charged fragments for diffractive excitation of 1.88A GeV ^Fe heavy ion are well fitted by Gaussian distribution function with peaks having (γ_a-η_b)_max=3.30 and (γ_p-η_b)_max=2.24.

Therapeutic targeting of subdural medulloblastomas using human neural stem cells expressing carboxylesterase

Lim, S-H,Choi, S A,Lee, J Y,Wang, K-C,Phi, J H,Lee, D-H,Song, S H,Song, J H,Jin, X,Kim, H,Lee, H J,Lim, I,Kim, S U,Kim, S-K Nature America, Inc. 2011 Cancer gene therapy Vol.18 No.11

The prognosis of medulloblastoma has improved significantly because of advances in multi-modal treatments; however, metastasis remains one of the prognostic factors for a poor outcome and is usually associated with tumor recurrence. We evaluated the migratory potential and therapeutic efficacy of genetically engineered human neural stem cells (NSCs) that encode a prodrug enzyme in the subdural medulloblastoma model. We genetically modified HB1.F3 (F3) immortalized human NSCs to express rabbit carboxylesterase (rCE) enzyme, which efficiently converts the prodrug CPT-11 (Irinotecan) into an active anti-cancer agent (SN-38). To simulate clinical metastatic medulloblastomas, we implanted human medulloblastoma cells into the subdural spaces of nude mice. rCE expressing NSCs (F3.rCE) were labeled with fluorescence magnetic nanoparticle for in vivo imaging. The therapeutic potential of F3.rCE was confirmed using a mouse subdural medulloblastoma model. The majority of intravenously (i.v.) injected, F3.rCE cells migrated to the subdural medulloblastoma site and a small number of F3.rCE cells were found in the lungs, pancreas, kidney and liver. Animals that received F3.rCE cells in combination with prodrug CPT-11 survived significantly longer (median survival: 142 days) than control mice that received F3.rCE cells only (median survival: 80 days, P<0.001) or CPT-11 only (median survival: 118 days, P<0.001). In conclusion, i.v. injected F3.rCE NSCs were able to target subdural medulloblastomas and demonstrate therapeutic efficacy. Our study provides data that supports further investigation of stem-cell-based gene therapy against metastatic medulloblastomas.

충청지역에서 발생한 쭈쭈가무시병의 임상상, 원인균의 혈청형 및 혈청역학적 연구

김선영,김윤성,박장규,윤태영,강재승,송인숙,최명식,최인학,차창룡,이우곤,박종우,이증훈,장우현,유영해,윤광혁,송계용 대한감염학회 1989 감염 Vol.21 No.2

From September to december 1987, eighty-six cases of tsutsugamushi disease were diagnosed by indirect immunofluorecent test or by isolating the causative agent in Chungcheung area. Their clinical features and patterns of antibody response to R. tsutsugamushi were analyzed. For the indenfication of prevalent antigenic types of R. tsutsugamushi in Chungcheung area, twenty-seven strains isolated were tested by indirect immunofluorescent test. To assess the extent of exposure to R.tsutsugamushi of a general population in Korea, the prevalence of antibody was investigated in 6,572 sera obtained from the residents of Chungcheung area by indirect immunofluorescent test. The female patients slightly outnumbered the male patients. More cases (68%) were older than 40 years of age. The epidemic peaked in October. The mean incubation period estimated was about 8 days. The major clinical features were fever and chill, headache, rash, eschar, and lymphadenopathy. Increased serm transaminase was the most singificant laboratory findings. Abnormalities in the chest roentgenography were often observed. The antibody titer rose rapidly 5 days after the onset, reached its peak at 20 days (1:640), and then declined agradually until 7 months(1:20). The seroype of 23 out of the 27 isolates wase found to be karp, one was Gilliam, and 3 isolates could not be classified by using polyclonal mouse hyperimmune sera. The prevalence of antibody to R.tsutsugamushi in the residents of Chungcheung area was 4.8%. The prevalence of antibody was higher in the female than in the male. The prevalence was higher in the residents of age above 40 years than below 40 years, and was the lowest in the children less than 10 years of age. Of the 318 positive sera from normal residents, only 2 sera showed the titers higher than 1:80.