주성분 기법에 의한 전주천 수계의 수질평가

장경호 ( Koung-ho Jang ),박영기 ( Young-ki Park ),이동주 ( Dong-joo Lee ) 한국환경기술학회 2015 한국환경기술학회지 Vol.16 No.2

본 연구의 목적은 PCA를 사용하여 전주천의 주 수질 오염원을 평가하는데 있다. 자료는 전라북도 보건환경연구원의 1984년 ~ 1990년 동안의 총 8개 수질데이터가 이용되었다. PCA를 사용하여 3개 주성분(Highly factor, Medium factor, Less factor)을 평가하였으며, 수질항목에 대하여 HF(T-N) 50.3%, MF(SS) 17.7%, LF(COD) 13.3%로 나타났다. 수질 관측지점에 대해서는 HF(이성보) 84.3%, MF(전주천 6) 8.73%, LF(전주천 5) 4.55% 등으로 평가되었다. 수질항목, 관측지점 주성분을 직각회전기법(Varimax rotation)에 적용한 결과, 주성분의 모양이 요인축에 따라 그룹화 모양을 나타냈다. 이 모양에 의하면 주성분이 PCA에 의하여 평가되었다고 볼 수 있으며, PCA는 수질평가에 효과적인 기법이라 생각된다. The purpose of this study was to estimate the principal water quality pollution sources at the Jeon-Ju stream using PCA(Principal Component Analysis). All together, eight water quality factors (temperature, pH, DO, BOD, COD, SS, T-N, and T-P) 1984 ~ 1990 of Jeollabukdo Institude of Health & Environment Research were used by PCA and varimax factor rotation tool. The PCA assess three principal factors; relatively highly factor(HF), medium factor (MF), and less factor(LF). The result of application for water quality factors as follows. The HF(T-N) was 50.3%, MF(SS) was 17.7%, and LF(COD) was 13.3%. For water quality stations, the HF(Lee-sung bo), MF(Jeon-Ju stream 6) and LF(Jeon-Ju stream 5) were estimated to be 84.38%, 8.73% and 4.55%, respectively. The result of application for water quality factors and observing stations, the form of the principal factors shows grouping according to factors axis. According to this phenomenon, It was considered that principal component was response to results by PCA. The result of this study is demonstrated that PCA is very effective tool of analysis and interpreation for multi-water quality parameter and multi-station data sets.

cobas 항-Cyclic Citrullinated Peptide 항체 검사의 분석능 평가

이경선,박도심 원광대학교 의과학연구소 2009 圓光醫科學 Vol.24 No.1

Background: Anti-cyclic citrullinated peptide(CCP) antibody is very useful test for diagnosis of rheumatoid arthritis(RA) because of its high specificity. However, the test has been developed for ELISA(enzyme-linked immunosorbent assay) method, it has a limitation to get a rapid result or deal with small number of tests. In this study we evaluated the analytical performance of cobas anti-CCP test(cobas), which has developed recently, has random accessibility and can be applied on automated immunochemical analyzer, to know appropriate clinical applications. Methods: cobas(Roche Diagnostics GmBH Mannheim, Germany) was performed on automated immunochemical analyzer. The imprecision and linearity were evaluated using commercialized controls and pooled sera. Sixty serum samples(26 RA, 34 controls) were measured by cobas and ELISA method(DIASTAT; Axis-Shield Diagnostics, UK)to define the correlation, sensitivity, specificity, and agreement of both tests. Results: cobas showed less than 5% of imprecision and its linearity was retained up to 639 U/mL. It showed good correlation with DIASTAT(R=0.90). The diagnostic sensitivity was 84.6% and specificity was 88.3%. The qualitative agreement with DIASTAT was 95.0%. Conclusions: Automated cobas anti-CCP test showed acceptable analytical performance as a semi-quantitative test and high agreement rate with DIASTAT anti-CCP test. Considering random access capability and short analytical processing time of cobas anti-CCP assay, it will be useful in laboratories with small sample sizes and/or with a need of rapid turnaround time. 배경 : 항-CCP 항체는 류마티스 관절염의 혈청학적 표지자로 특이도가 높아 류마티스 진단에 매우 유용하나, ELISA법 검사로 개발되어 소수 검사나 신속 검사에 활용하기에는 어려운 단점이 있었다. 본 연구에서는 자동화된 면역화학 장비에 적용하여 임의 액세스가 가능한 방법으로서 최근에 개발된 cobas 항-CCP 항체 검사(cobas)의 분석능을 조사하여 적절한 임상적 활용성을 검토하고자 하였다. 방법 : cobas(Roche Diadnostics GmBH Mannheim, Germany)는 자동면역화학 장비를 이용하여 실시하였다. 상품화된 대조 물질 및 혼주 혈청을 이용하여 정밀성, 직선성을 평가하였다. 상관성, 민감도, 특이도, 검사간 일치도 평가를 위해 총 60명의 검체(26명 류마티스 관절염, 대조군 34명)를 cobas 및 ELISA법(DIASTAT; Axis-Shield Diagnostics, UK)으로 분석하였다. 결과 : cobas는 5% 미만의 변이계수를 보였고, 639 U/mL 이하의 범주에서 적절한 직선성이 확인되었다. DIASTAT과 비교한 상관성 평가에서는 상관 계수는 0.90으로 좋은 상관성을 보였다. 진단적 민감도는 84.6%, 특이도는 88.3%였고, 두 검사간 정성적 일치도는 95.0%였다. 결론 : cobas는 반정량 검사로서 적절한 분석능을 보였으며, DIASTAT과도 높은 일치율을 보였다. cobas의 임의 액세스 기능과 짧은 분석 시간을 고려할 때 cobas는 검체 수가 적은 검사실이나 신속한 결과가 필요한 검사실에서 유용하리라 사료된다.

알콜의 산화-탈수소 반응공정의 안전조작

이상록,여경희,최재욱,김상열 동아대학교 공과대학 부설 한국자원개발연구소 1994 硏究報告 Vol.18 No.2

The effect of the temperature and the concentration of the reactor inlet gas on the safe operation of a fixed-bed reactor for exothermic-endothermic Catalytic process is investigated. The important industrial process of vapour phase oxidation-dehydrogenation of methanol into formaldehyde is used as an example. The safe operation of steam addition, air/methanol ratio and feed temperature is performed to be outside the flammable region. And it is also essential to prevent the possible explosion.

미세혈관 수술후 Urokinase투여효과에 관한 실험적 연구

이세일,오석준,김용성,양경무 大韓成形外科學會 1987 Archives of Plastic Surgery Vol.14 No.1

However, even the most technically perfect anastomosis can neither eliminate the damage which microneedles cause on the vascular endothelium nor foreign body reaction to the suture material. Thrombosis developed at the suture site and regressed if the stimulus for the thrombosis is not severe. Partial thrombosis was inevitable after microvascular anastomosis. Since systemic thrombolytic drugs were used initially in the management of pulmonary emboli, urokinase were also used in prevention of thrombolysis and thrombolysis after microvascular anastomsis. This experimental study includes the effect of urokinase on the microvascular anastomosis in rabbits. The patency was observed, and platelet count, fibinogen, prothrombin time, and activated partial thromboplastim time were examined. In the case of thromboses, the anastomotic sites were resected and examined microscopically. The results were as follow; 1. The patency rate was increased 15 percent in experimental group than control group. 2. There were no differences in platelet count and the prothrombine time between experimental and control group. 3. The level of fibrinogen was decreased 157㎎/dl in experimental group less than control group. 4. The activated partial thromboplastin time was increased three to four times at postoperative period more than preoperative period in experimental group. 5. In light microscopic examination of thrombotic vessel wall revealed inflammatory reaction to suture material. In the experimental group, the thrombi were loose and defibrinated than control group.

纖維의 耐侯性에 關한 硏究

金桂蓮,李京任,李貞淑 효성여자대학교 가정대학 학도호국단 1984 家政大論集 Vol.3 No.-

Even though the weather resistance of fiber is a very important subject, there are not many term paper. If one places fibral wear in the weather of under similiar conditions ultraviolet light will cause lowering of the goods quality, expecially the strength and elongation factor will become lower and also results in decoloration. In this experiment using endurdence's most basic out-door method we are trying to estimate cotton, silk, rayon, nylon, acryl fiber's weather resistance in the sense of the change in strength. The results that we got were, 1. The fiber with the greatest resistance was acryl and least were silk. 2. Exhaust gas cuts off ultraviolet light and the result is decrease of fibers change. 3. The elongation percentage of cotton and rayon rise at first and than decrease as time go on.

컴퓨터 비젼 방법을 이용한 3차원 물체 위치 결정에 관한 연구

장완식,김경석,이성민,주철,김재확,김대현 한국공작기계학회 1999 한국생산제조학회지 Vol.8 No.6

This study shows an alternative method for the determination of object's position, based on a computer vision method. This approach develops the vision system model to define the reciprocal relationship between the 3-D real space and 2-D image plane. The developed model involves the bilinear six-view parameters, which is estimated using the relationship between the camera space location and real coordinates of known position. Based on the estimated parameters in independent cameras, the position of unknown object is accomplished using as sequential estimation scheme that permits data of unknown points in each of the 2-D image plane of cameras. This vision control method is the robust and reliable, which overcomes the difficulties of the conventional research such as precise calibration of the vision sensor, exact kinematic modeling of the robot, and correct knowledge of the relative positions and orientation of the robot and CCD camera. Finally, the developed vision control method is tested experimentally by performing determination of object position is the space using computer vision system. These results show the presented method is precise and compatible.

柴胡桂枝湯이 CCl₄로 誘發된 白鼠의 肝損傷에 미치는 影響

河智容,朴慶寔,李善熙 대한동의병리학회 1996 동의생리병리학회지 Vol.10 No.2

肝은 人體內의 血量을 調節하고 각종 大事, 分泌, 合成에 관여하는 중요한 기관이며, 病理的으로는 대사물질에 의한 중독에 민감하게 반응하여 간세포의 변성, 괴사, 지방축적, 간효소의 누출 등을 일으킨다. 간에 손상을 줄 수 잇는 요인 은 많으며, 최근에는 중독에 의한 손상이 증가하고 있다. 시호계지탕은 상한론에 ‘傷寒六七日 發熱徵惡寒 肢節煩疼 徵嘔 心下支結 外證未去者 柴胡桂枝湯主之에 사용된 처방으로 임상적으로 간손상에 사용되었으나, 실험적 연구는 실시되지 않앗다. 따라서 본 연구에서는 Sprague-Dawely 흰쥐에 사염화탄소로 중독성 간손상을 일으킨 후 시호계지탕을 투여하여 간손상에 미치는 영향을 알아보았다. Sprague-Dawely 흰쥐에 CCI₄와 Olive oil을 1:4로 혼합하여 4주간 격일로 경구투여하여 간손상을 유발하였다. 그 후 시호계지탕을 10㎎/㎏(B.W)로 하여 매일 경구투여 하였다. 실험 첫주부터 매주 각 군의 평균몸무게와 평균 사료섭취량을 측정하였고, 실험 마지막날 채혈한 뒤 순수혈청에서 AST, ALT, TP, Albumin, Gloulin, ALP, LDP를 검사 하였다. AST는 CCI₄處理群에 비하여 CCI₄處理後柴胡桂枝湯投與群 A와 CCI₄處理後柴胡桂枝湯投與群 B 모두 減少하였으며, CCI₄處理後柴胡桂枝湯投與群 B의 境遇는 有意性이 認定되었다. (P〈0.05). ALT는 CCI₄處理群에 비하여 CCI₄處理後柴胡桂枝湯投與群 A와 CCI₄處理後柴胡桂枝湯投與群 B 모두 유의성있는 감소를 보였다. (P〈0.05). CCI₄處理群과 比較하여 CCI₄處理後柴胡桂枝湯投與群 A와 CCI₄處理後柴胡桂枝湯投與群 B는 Tota protein의 경우 큰 차이가 없었으며, Albumin은 감소하였고, Globulin은 增加하였으나 有意性은 없었다. Albumin과 Globulin의 比率은 減少하였으나, 有意性은 없었다. ALP는 CCI₄處理群에 比하여 CCI₄處理後柴胡桂枝湯投與群 A와 CCI₄處理後柴胡桂枝湯投與群 B 모두 有意性있는 減少를 보였다.(P〈0.05). LDH는 특별한 傾向을 찾을 수 없었다. 肝의 重量을 測定한 結果 CCI₄處理後群에 比하여 CCI₄處理後柴胡桂枝湯投與群 A와 CCI₄處理後柴胡桂枝湯投與群 B 모두 有意性 있는 減少를 보였다. (P〈0,05). 體重과 飼科 攝取量의 變化는 CCI₄處理群에 比하여 CCI₄處理後柴胡桂枝湯投與群 A와 CCI₄處理後柴胡桂枝湯投與群 B이 增加하였으나 유의성은 없었다. 以上으로 보아 柴胡桂枝湯이 CCI₄로 誘發된 肝損傷의 境遇에 AST, ALT, ALP, 肝의 重量變化에서 有意性있는 減少(P〈0.05)를 보였으며, 體重과 飼科 攝取量의 增加로 보아 肝損傷 回復에 대한 治療效果가 있을 것으로 思料된다. This study was carried out to investigate the effects of Sihogyejitang extract on the recovery of liver in CCI₄-intoxicated rats. In this study, SD-Rats were divided into 4 experimental groups; Control(Placebo, 0.85% NaCl), Experi-mental (CCI₄-intoxicated+Placebo, 0.85% NaCl), Siho A(Treated with Sihogyejitang extract (10㎎/㎏) after CCI₄intoxication), Siho B(Treated with Sihogyejitang extract (50㎎/㎏) after CCI₄-intoxication), Biochemical assays for serum enzyme activities such as AST, ALT, TOtal protein, Albumin, Globulin, ALP, LDH, and Biological assay for Liver weight, Body weight, Food, intake were performed. The results obtained were summarized as follows: 1. Siho A group showed lower serum AST activity than CCI₄-intoxicated group significantly, and Siho B group showed lower than Control group(P〈0.05). 2. Both siho A group and siho B group showed lower serum ALT activity than CCI₄-intoxicated group significantly. 3. As to Total protein, Siho A group and Siho B group were classed with CCI₄-intoxicated group. As to Albumin, Siho A group and siho B group were decreased than CCI₄-intoxicated gruop, but not significant. As to Globulin, siho A group and B group were increased than CCI₄-intoxicated group, but not significant. As to Globulin, ratio siho A group and Siho B group were decreased than CCI₄-intoxicated group, but not significant. 4. As to ALP, Siho A group and Siho B group were decreased than CCI₄-intoxicated group significantly(P〈0,05). 5. As to serum LDH, There were no trend in all groups. 6. As to liver weight, Siho A group and Siho B group were decreased than CCI₄-intoxicated group significantly. 7. As to Body weight and Food intake, Siho A group and Siho B group were increased than CCI₄-intoxicated group, buy not significantly.

레이저 스페클간섭법에 있어서 스페클크기와 측정 한계에 관한 연구

윤성운,김경석,양승필,정현철,김정호,이도윤 한국공작기계학회 1996 한국생산제조학회지 Vol.5 No.1

The high coherence of laser beam has made it possible to observe interference effects even in the light scattered from rough surfaces. That's why, when object with a scattering surface is illuminated with laser light, we do see a speckled appearance due to random interference. This sort of unique property of laser speckle has brought into existence the new noncontacting techniques such as speckle metrology method of measuring deformation, displacement, and vibration etc of objects with high optical sensitivity. The measurable range of speckle metrology especially used to measure in-plane information, however, is limited by some factors, the so-called strain, rotation, tilt of surface and out of displacement perpendicular to the plane of analysis. This restrictions severly limits the measurable range of speckle metrology by causing the decorrelation of speckle patterns. It is the purpose of this paper to give a survey on the measurable limitation of speckle photography method that is one of speckle metrology. Namely we will discuss the mutual relationships and problems of each limitations adding the restriction of the largest and smallest displacement measurable with speckle methods.

토착형 P. vivax에 의한 Malaria 4례

박형렬,이성원,이경미,김태겸,한진영,손춘희,정원태,김성은,김종성 동아대학교의과대학 1997 동아의대학술지 Vol.9 No.2

Influence of Hydrofluoric Acid on Soil Microorganisms and Physicochemical Properties of Soils

Lee, Youn Koung(이연경),Dong Sung Lee(이동성),Kyo Suk Lee(이교석),Dae Sung Jeon(전대성),Mi suk Park(박미숙),Ji Su Shin(신지수),Ji Won Goo(구지원),Soo Bin Kim(김수빈),Na Won Park(박나원),Ye Jin Park(박예진),So Jin Kim(김소정),Bo Koung 한국토양비료학회 2014 한국토양비료학회 학술발표회 초록집 Vol.2014 No.10