쉰소리로 발현한 흉부 대동맥류 1예 : Ortner씨 증후군 orther`s syndrome

장이선,진승원,박희철,박진아,윤희정,이종민,김재형 대한내과학회 2003 대한내과학회지 Vol.64 No.1

Ortner씨 증후군은 다양한 심장 질환에 이차적으로 생긴 반회 후두 신경 마비에 의한 쉰소리를 특징으로 하는 임상 질환이다. 저자들은 흉통없이 발생한 쇤소리를 주소로 내원한 환자에서 좌측 반회 후두 신경의 손상에 따른 성대 마비의 1차원적인 원인으로 대동맥궁 부위에서의 대동맥류를 진단하였기에 문헌 고찰과 더불어 보고하는 바이다. Ortner's syndrome is a clinical entity with hoarseness due to a left recurrent laryngeal nerve palsy caused by cardiac disease. It is a recognized complication of a number of conditions including, atrial septal defect, patent ductus arteriosus, primary pulmonary hypertension, Eisenmenger's syndrome and aortic aneurysm. A 71-year-old woman with a history of hypertension and diabetes complained hoarseness and hemoptysis for 3 days. Chest X-ray showed a soft tissue mass shadow in the left upper lung field and chest CT scan revealed a thoracic aortic aneurysm. We report a case of left recurrent laryngeal nerve palsy due to a huge thoracic aortic aneurysm in an old woman. (Korean J Med 64:105-108, 2003)

청소년의 태권도 수련활동 참가에 따른 예절의식과 청소년 비행의 관계

이은석,이선장 한국스포츠리서치 2003 한국 스포츠 리서치 Vol.20 No.1

The purpose of this study is to analyze the The Relationship between Etiquette Awareness and Juvenile Delinquency along with Participation in Adolescent' Taekwon-do Practice. To accomplish the purpose of this study, the 421 subjects were selected using the systematic stratified cluster random sampling method from students who study in middle and high school in Seoul 2003. The Survey questionaries were used to collect data. The questionaries for Participation in Taekwon-do Tranining was Sport Participation and degree on Scale developed by Kenyon and Schuts(1970), and etiquette awareness standardized by Jang, Kyoung-Sun(1993). And the questionaries for Juvenile Delinquency scale was Expansion developed by Jung(1988) and Lim(1986). The statistical methods utilized in this study for analyzing the collected data were reliability analysis, descriptive statistics, One-way ANOVA, and multiple regression analysis. From the analysis of this study, the following conclusions were obtain:. Firstly, adolescent' Taekwon-do practice participation are different according to etiquette awareness. In detail, the Taekwon-do practice participation group are lower in the delinquency than the non-participation and the participation in adolescent's Taekwon-do practice partially influence on the etiquette awareness. Secondly, adolescent' Taekwon-do practice participation are different according to juvenile delinquency. In detail, the Taekwon-do practice participation group are lower in the delinquency than the non-participation and the participation in adolescent's Taekwon-do practice partially influence on the juvenile delinquency. Thirdly, adolescent's etiquette awareness through participation in adolescent's Taekwon-do practice influence on the juvenile delinquency. In detail, the higher etiquette awareness, the higher juvenile delinquency.

LETTER TO THE EDITOR : Diagnosis of cyclic Cushing syndrome using the morning urine free cortisol to creatinine ratio

( Yi Sun Jang ),( Ihn Suk Lee ),( Jong Min Lee ),( Soo A Choi ),( Gi Jun Kim ),( Hye Soo Kim ) 대한내과학회 2016 The Korean Journal of Internal Medicine Vol.31 No.1

시화지구의 대기오염물질 확산에 관한 전산모사

이성철,홍민선,송은석,류진복,김병수,장영기 한국환경영향평가학회 1998 환경영향평가 Vol.7 No.1

Gaussian type models have limitations on predicting a detailed description of the near flow and pollution leads over complex terrains under neutral atmospheric conditions. Also, most models used recently have lack of ability to include atmospheric reactions. The model based on the numerical solution of the time-averaged Navier-Stokes equations and conservation equations needs to be developed to improve the limitations mentioned above. When the model was applied to the Shihwa area where the tracer experiment had been carried out, the simulation results have a great difference from the experimental result. There are two reasons that make the difference between the results by the model and the experiment First, the Shihwa area is not a complex terrain. Second, meteorological data is insufficient. Therefore, the model should be applied to predict they dispersion of air pollutants over complex terrain rather than flat terrain in order that the model could be verified because the model was developed for the prediction of the dispersion over a complex terrain.

Association between Exposure to Traffic-Related Air Pollution and Prevalence of Allergic Diseases in Children, Seoul, Korea

Yi, Seon-Ju,Shon, Changwoo,Min, Kyung-Duk,Kim, Hwan-Cheol,Leem, Jong-Han,Kwon, Ho-Jang,Hong, Soyoung,Kim, KyooSang,Kim, Sun-Young Hindawi 2017 BioMed research international Vol.2017 No.-

<P>Although there has been suggestive evidence of the association between TRAP and ADs, findings remained inconsistent possibly due to limited population. We investigated the association between TRAP and ADs in a large population of children with rich spatial coverage and expanded age span in Seoul, Korea. TRAP exposures were estimated by categorized proximity to the nearest major road (≤150, 150–300, 300–500, and >500 m) and density of major roads within 300 meters from children's residences. We estimated the association between two TRAP exposures and three ADs using generalized mixed model after adjusting for individual characteristics. We also investigated whether the association varied by household and regional socioeconomic status. We found associations of atopic eczema with road density [OR = 1.08; 95% CI = 1.01–1.15] and road proximity [1.15, 1.01–1.32; 1.17, 1.03–1.34; and 1.16, 1.01–1.34 for ≤150, 150–300, and 300–500 m, resp., compared to >500 m]. There was no association with asthma and allergic rhinitis. Effect estimates were generally the highest in the low socioeconomic region. Children living in areas surrounded by large and busy roads were likely to be at greater risks for atopic eczema, with increased vulnerability when living in deprived areas.</P>

유아 교육을 위한 그림 자료 검색 편집 프로그램의 개발

장선화,선섭희,이명재 한국컴퓨터교육학회 2000 컴퓨터교육학회 논문지 Vol.3 No.1

In children education, it takes a much time for teachers to prepare teaching materials and tools. Most teaching materials and tools consist of pictures so that children may easily understand the contents of a study. If instructors free from laborious work for preparing these materials, they can provide children with better education by focusing more creative works. In this study, we manufactured many picture data which are used in children education, and developed a program that is used by teachers for the purpose of utilizing these pictures according to study topics. This program provides a feature that easily search more than 3700 pictures according to subjects and areas, and also provides various editing facilities such as expanding, reducing pictures and writing statements.

Interleukin 10 rs1800872 T>G Polymorphism was Associated with an Increased Risk of Esophageal Cancer in a Chinese Population

Sun, Jia-Ming,Li, Qiong,Gu, Hai-Yong,Chen, Yi-Jang,Wei, Ji-Shu,Zhu, Quan,Chen, Liang Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.6

Aim: Esophageal cancer is the eighth most common cancer and sixth leading cause of cancer associated death worldwide. The 5 year survival rate for esophageal cancer patients is very poor and accounts for only 12.3%. Besides environmental risk factors, genetic factors might play an important role in the esophageal cancer carcinogenesis. Methods: We conducted a hospital based case-control study to evaluate the genetic effects of functional single nucleotide polymorphisms (SNPs): interleukin 9 (IL9) rs31563 C>T, IL9 rs31564 G>T, IL10 rs1800872 T>G, IL12A rs2243115 T>G, IL12B rs3212227 T>G and IL13 rs1800925 C>T on the development of esophageal cancer. A total of 380 esophageal squamous cell carcinoma (ESCC) cases and 380 controls were recruited for this study. The genotypes were determined using a custom-by-design 48-Plex SNPscan$^{TM}$ Kit. Results: The IL10 rs1800872 T>G polymorphism was associated with an increased risk of ESCC. However, there were no significant links with the other five SNPs. Stratified analyses indicated no significant risk of ESCC associated with the IL10 rs1800872 T>G polymorphism evident among any subgroups. Conclusion: These findings indicated that functional polymorphism IL10 rs1800872 T>G might contribute to ESCC susceptibility. However, our results were obtained with a limited sample size, so that the power of our analysis was low. Future larger studies with more rigorous study designs of other ethnic populations are required to confirm the current findings.

RU486 Suppresses Progesterone-induced Acrosome Reaction in Boar Spermatozoa

( Sun Phil Jang ),( Lee S. H. Yi ) 생화학분자생물학회 2002 BMB Reports Vol.35 No.6

The effects of progesterone on the acrosome reaction, as well as the effects of RU486 on the progesterone-induced acrosome reaction in capacitated boar spermatozoa, were investigated. Progesterone, a major steroid that is secreted by the cumulus cells of oocyte, clearly induced the acrosome reaction in a dose-dependent manner in capacitated boar spermatozoa, even though it failed to show similar effects in non-capacitated spermatozoa. RU486, a potent antiprogestin, significantly reduced the effects of progesterone on the progesterone-induced acrosome reaction; however, when treated alone, it showed no inhibitory effects on the acrosome reaction. The inhibitory effects of RU486 were also shown to be dose-dependent. These results imply that in addition to the well-known inducer of the acrosome reaction, zona pellucida, progesterone can also induce the acrusome reaction through its specific receptors on spermatozoa after the spermatozoa undergo capacitation.

Invited Mini Review : Polo-like kinase-1 in DNA damage response

( Sun Yi Hyun ),( Hyo In Hwan ),( Young Joo Jang ) 생화학분자생물학회(구 한국생화학분자생물학회) 2014 BMB Reports Vol.47 No.5

Polo-like kinase-1 (Plk1) belongs to a family of serine-threoninekinases and plays a critical role in mitotic progression. Plk1involves in the initiation of mitosis, centrosome maturation,bipolar spindle formation, and cytokinesis, well-reported astraditional functions of Plk1. In this review, we discuss the roleof Plk1 during DNA damage response beyond the functions inmitotsis. When DNA is damaged in cells under various stressconditions, the checkpoint mechanism is activated to allowcells to have enough time for repair. When damage is repaired,cells progress continuously their division, which is calledcheckpoint recovery. If damage is too severe to repair, cellsundergo apoptotic pathway. If damage is not completelyrepaired, cells undergo a process called checkpoint adaptation,and resume cell division cycle with damaged DNA. Plk1targets and regulates many key factors in the process of damageresponse, and we deal with these subjects in this review.[BMB Reports 2014; 47(5): 249-255]

Difference of Antioxidant Activities and Polyphenol Contents by Fermented Conditions of Tea Leaves

Sun Yim Jung,Dong Jin Lee,Heon Woong Kim,Jae Sung Lee,Sang Il Lee,Yi Kwan Yoon,Ka Hee Jang 한국응용생명화학회 2008 Applied Biological Chemistry (Appl Biol Chem) Vol.51 No.5