소취식물이 김치 냄새특성 및 발효성에 미치는 영향

최아름(A Reum Choi),박동일(Dong Il Park),손민희(Minhee Son),김소영(Soyoung Kim),장재범(Jae Beom Jang),권상철(Sang Chul Kwon),채희정(Hee Jeong Chae) 한국식품과학회 2010 한국식품과학회지 Vol.42 No.1

본 연구에서는 천연소취식물인 감잎, 솔잎, 회향을 세절 및 추출하여 김치에 첨가하여 냄새를 masking하는 농도의 조건을 설정하고, 천연물 첨가에 따라 김치의 숙성에 미치는 연향과 휘발성 향기 성분을 분석하였다. 감잎, 솔잎, 회향을 세절물과 추출물로 김치에 첨가하여 숙성 후 신내와 군덕내에 대해 관능평가한 결과, 김치에 천연소취식물을 첨가할 때 세절물보다 추출물을 첨가했을 경우에 김치냄새의 masking 효과가 높았으며, 솔잎추출물 0.3-0.6%를 첨가한 김치와 회향추출물 0.05-0.1%를 첨가한 김치가 관능적으로 효과가 높았다. 또한 솔잎추출물 및 회향추출물을 첨가한 김치는 일반김치와 비교했을 때 pH, 총산도 및 유산균수 등의 발효특성인자들에 유의적으로 영향을 미쳤다. 또한 GC/MS로 김치 및 소취식물 추출물의 향기 성분을 분석하여, 천연소취식물을 첨가한 김치와 솔잎 및 회향추출물의 향기 성분과의 연관성을 검토하였다. 결과적으로 솔잎 및 회향추출물은 김치의 발효특성에 영향을 주어 김치 특유의 냄새를 저감시킬 수 있는 것으로 확인되었다. The use of deodorizing plant products such as persimmon leaves, pine needles and fennel seeds to mask the characteristic odor of kimchi has been proposed. Therefore, in this study, the effect of deodorizing plants on kimchi fermentation and the profile of volatile flavor compounds was investigated. During sensory evaluation tests of sour and fermentation odors of kimchi, plant extract-added kimchi showed higher sensory scores than chopped plant-added kimchi. Additionally, kimchi containing pine needle extracts (0.3-0.6%) and fennel seed extracts (0.05-0.1%) showed higher sensory scores than untreated kimchi. In addition, pine needle extract and fennel seed extract had a significant influence on kimchi fermentation characteristics such as pH, total acidity and the concentration of lactic acid bacteria. The volatile flavor compounds of kimchi and deodorizing plant extracts were also analyzed using GC/MS and the correlation of volatile flavor compounds in kimchi, plant extracts and plant-added kimchi was examined. The results revealed that the sour and fermentation odors of kimchi were reduced using deodorizing plant extracts by changing the kimchi fermentation characteristics.

Outcome of Multipair Donor Kidney Exchange by a Web-Based Algorithm

Kim, Beom Seok,Kim, Yu Seun,Kim, Soon Il,Kim, Myoung Soo,Lee, Ho Yung,Kim, Yong-Lim,Kim, Chan Duck,Yang, Chul Woo,Choi, Bum Soon,Han, Duck Jong,Kim, Yon Su,Kim, Sung Joo,Oh, Ha-Young,Kim, Dae Joong American Society of Nephrology 2007 Journal of the American Society of Nephrology Vol.18 No.3

<P>Donor kidney exchange is an established method to overcome incompatibility of donor-recipient pairs (DRP). A computerized algorithm was devised to exchange donor kidney and was tested in a multicenter setting. The algorithm was made according to the consensus of participating centers. It makes all possible exchange combinations not only between two incompatible DRP but also circularly among three DRP and selects an optimum set of exchange combinations, considering several factors that can affect the outcome of the exchanged transplant. The algorithm was implemented as a web-based program, and matching was performed five times. Fifty-three DRP were enrolled from five transplant centers. The numbers of DRP that were enrolled in each matching were 38 (25:13), 39 (34:5), 33 (31:2), 32 (28:4), and 34 (30:4) (carryover:newcomer). The numbers of generated exchange combinations were 4:11, 3:17, 2:12, 2:3, and 2:3 (two-pair exchange:three-pair exchange), and the numbers of DRP in selected exchange combinations were six, 12, six, five, and four in each matching. The numbers of DRP with blood type O recipient or AB donor were five and one, respectively, in selected exchange combinations. Six DRP of two-pair exchange combinations and six DRP of three-pair exchange combinations underwent transplantation successfully. Computerized algorithm of donor kidney exchange was tried not only between two incompatible DRP but also circularly among three DRP. It showed that the algorithm has potential to improve the outcome of donor kidney exchange, especially for disadvantaged DRP with blood type O recipients or AB donors.</P>

Online Registry for Nationwide Database of Current Trend of <i>Helicobacter pylori</i> Eradication in Korea: Interim Analysis

Kim, Beom Jin,Kim, Hyun-Soo,Song, Hyun Joo,Chung, Il-Kwun,Kim, Gwang Ha,Kim, Byung-Wook,Shim, Ki-Nam,Jeon, Seong Woo,Jung, Yun Jin,Yang, Chang-Hun,Kim, Ji Hyun,Kim, Tae Ho,Kim, Sang Gyun,Shin, Woon Ge The Korean Academy of Medical Sciences 2016 JOURNAL OF KOREAN MEDICAL SCIENCE Vol.31 No.8

<P>Eradication of <I>Helicobacter pylori</I> using first-line therapy is becoming less effective. Subjects who had been treated for <I>H. pylori</I> infection were prospectively enrolled through an on-line database registry from October 2010 to December 2012. Demographic data, detection methods, treatment indication, regimens, durations, compliance, adverse events, and eradication results for <I>H. pylori</I> infection were collected. Data of 3,700 patients from 34 hospitals were analyzed. The overall eradication rate of the first-line therapy was 73.0%. Eradication failure was significantly associated with old age, concomitant medication, and comorbidity. Regional differences in eradication rates were observed. The most common first-line therapy was proton pump inhibitor-based triple therapy (standard triple therapy, STT) for 7 days (86.8%). The eradication rates varied with regimens, being 73% in STT, 81.8% in bismuth-based quadruple therapy, 100% in sequential therapy, and 90.3% in concomitant therapy. The eradication rate in treatment-naïve patients was higher than that in patients previously treated for <I>H. pylori</I> infection (73.8% vs. 58.5%, <I>P</I> < 0.001). The overall eradication rate for second-line therapy was 84.3%. There was no statistical difference in eradication rates among various regimens. <I>H. pylori</I> eradication rate using STT is decreasing in Korea and has become sub-optimal, suggesting the need for alternative regimens to improve the efficacy of first-line therapy for <I>H. pylori</I> infection.</P>

체부에 발생한 다발성 Kimura씨 병

김상일(Sang-Il Kim),손종민(Jong-Min Son),이상욱(Sang-Uk Lee),주선영(Sun-Young Joo),오인수(In-Soo Oh) 대한정형외과학회 2011 대한정형외과학회지 Vol.46 No.2

Kimura 병은 원인이 잘 알려져 있지 않은 드문 양성 림프 증식성 염증성 질환이다. 체부에 발생한 비압통성 다발성 종괴를 주소로 내원한 48세 남자환자에 대해 절제 생검술 후 조직병리학 결과, Kimura 병으로 진단하였다. 체부에 발생한 다발성 Kimura시 병에 대해 보고하고 이에 대한 문헌을 고찰하는 바이다. Kimura's disease is a very rare, benign, Iymphoproliferative inflammatory disorder of unknown etiology. A 48 year-old man had multiple soft tissue masses in his trunk, which was diagnosed as Kimura's disease by histopathologic evaluation. Here, we report the case with a review of the literature.

The Multifaceted Clinical Characteristics of Congenital Cytomegalovirus Infection: From Pregnancy to Long-Term Outcomes

Kim Yejin,Kim Yoo-min,Kim Doo Ri,Kim Han Gyeol,Sung Ji-Hee,Choi Suk-Joo,Oh Soo-young,Kim Yae-Jean,Chang Yun Sil,Kim Dongsub,Kim Jung-Sun,Moon Il Joon,Roh Cheong-Rae 대한의학회 2023 Journal of Korean medical science Vol.38 No.32

Background: The aim of this study was to capture multifaceted clinical characteristics of congenital cytomegalovirus (CMV) infection from diagnosis to treatment using a multidisciplinary approach including obstetrics, pediatrics, pathology, and otorhinolaryngology-head and neck surgery. Methods: This is a retrospective study including 30 consecutive cases of congenital CMV infection that were diagnosed at a single tertiary hospital located in Seoul, Korea from January 2009 to December 2020. Congenital CMV infection was defined as a positive result by polymerase chain reaction from urine, saliva or cerebrospinal fluid or positive CMV IgM from neonatal blood sampled within 3 weeks after birth. All cases were analyzed with respect to whole clinical characteristics from diagnosis to treatment of congenital CMV by a multidisciplinary approach including prenatal sonographic findings, maternal immune status regarding CMV infection, detailed placental pathology, neonatal clinical manifestation, auditory brainstem response test, and antiviral treatment (ganciclovir or valganciclovir). Long-term outcomes including developmental delay and hearing loss were also investigated. Results: The total number of births during the study period in our institution was 19,385, with the prevalence of congenital infection estimated to be 0.15%. Among 30 cases of congenital CMV, the median gestational age at delivery was 32.2 weeks [range, 22.6–40.0] and 66.7% of these infants were delivered preterm at less than 37 weeks. Suspected fetal growth restriction was the most common prenatal ultrasound finding (50%) followed by ventriculomegaly (17.9%) and abnormal placenta (17.9%), defined as thick placenta with calcification. No abnormal findings on ultrasound examination were observed in one-third of births. Maternal CMV serology tests were conducted in only 8 cases, and one case each of positive and equivocal IgM were found. The most common placental pathologic findings were chronic villitis (66.7%) and calcification (63.0%), whereas viral inclusions were identified in only 22.2%. The most common neonatal manifestations were jaundice (58.6%) followed by elevation of aspartate aminotransferase (55.2%) and thrombocytopenia (51.7%). After excluding cases for which long-term outcomes were unavailable due to death (n = 4) or subsequent follow up loss (n = 3), developmental delay was confirmed in 43.5% of infants (10/23), and hearing loss was confirmed in 42.9% (9/21) during the follow-up period. In our cohort, 56.7% (17/30) of neonates were treated for congenital CMV with ganciclovir or valganciclovir. Conclusion: Our data show that prenatal findings including maternal serologic tests and ultrasound have limited ability to detect congenital CMV in Korea. Given that CMV is associated with high rates of developmental delay and hearing loss in infants, there is an urgent need to develop specific strategies for the definite diagnosis of congenital CMV infection during the perinatal period by a multidisciplinary approach to decrease the risks of neurologic impairment and hearing loss through early antiviral treatment.

止浦 金坵의 詩文 연구 : 불교시문과 表箋文을 중심으로

김상일(Kim, Sang-Il) 동악어문학회 2020 동악어문학 Vol.80 No.-

이 글은 고려후기를 살았던 金坵(1211-1278)가 지은 시문의 제재적 성격과 문학적 품질을 분석한 것이다. 1. 김구의 시는 현재 14題 16首가 전한다. 먼저, 그의 시 중에는 매우 감각적인 작품이 있다. 특히 그의 詠物詩에 보이는 섬세한 관찰과 형상은 매우 뛰어나다. 이러한 그의 시 짓기 능력은 ‘시인의 솜씨’라 하겠다. 한편, 그의 『北征錄』에 실렸다는 시작품에는 사대부 의식이 투영되어 있다. 이런 점은 고려말 新興士大夫의 巡行詩의 作風과 조선시대의 燕行詩와 상통한다. 2. 김구의 불교시문은 그의 불교에 대한 깊은 인식을 보여준다. 그리고, 고려후기의 사회 현실에 대한 깊은 인식을 보여주는 점에 특징이 있다. 3. 김구의 시와 산문을 모아 엮은 『止浦集』에는 시 12제 외에도, 敎冊 5편, 啓 1편, 䟽 5편, 書 3편, 碑銘2편, 表箋 69편 등의 산문이 들어 있다. 이 중의 표전은 대개 몽고에 대한 외교문서로 지은 것인데, 당시 몽고의 강압적 요구에 대응해 오랜 전쟁으로 民生이 도탄에 빠진 현실을 들어 받아들이기 어렵다는 고려쪽의 의지가 짙게 투영되어 있다. 그러므로 이러한 표전은 文章報國을 위한 문장임을 알 수 있다. 따라서, 김구는 시문에 뛰어난 문신 관료 출신 작가로서, 불교에 대한 깊은 인식을 가지고 있었고, 고려사회에 대한 깊은 성찰을 토대로 抗蒙時期 위험에 처한 고려를 문장으로 구하고자 했던 表箋 전문의 작가였다고 하겠다. This paper analyzes the sanctions and literary quality of poems and prose written by Kim Gu (金坵), a late the Goryeo (高麗後期) writer. 1. Kim"s poem is currently only 14 episodes. There is a very sensual piece in his poem. In particular, the delicate observations and images of his youngmool [詠物] (the poems made of grass, trees, birds, and beasts) are outstanding. His ability to write poetry is called the poet"s skill. On the other hand, his Bookjeongrock [北征錄: A collection of poems written while traveling north.] is reflected in the idea of Confucian scholars. This is in common with the Joseon Dynasty (朝鮮) poems, which were created by visiting and visiting diplomats in Beijing(北京). 2. Kim"s Buddhist poetry (Buddhist poetry and prose) shows his deep appreciation of Buddhism. In addition, his Buddhist poems show deep reflection and recognition of society in the late Goryeo period. 3. The collection of Kim Poem"s poems and prose contains 14 poems, 5 books, 1 a long letter, 5 Prayer sentences, 3 letters, 2 writing on a tombstones, and 69 diplomatic documents. The representation of these was usually built during the time that Koryo (고려) opposed Mongolia (蒙古, 元). This expression contains diplomatic content, and the author"s willingness to overcome the dangerous situation that was considered at the time is deeply projected. Therefore, it can be seen that these symbols are for sentence-serving states (文章報國: sentence means to rescue the nation"s crisis). Therefore, it can be seen that Kim Gu was a Confucian scholars who had a deep understanding of Buddhism. And based on a deep reflection on Korea society, it can be seen that he was a professional writer who tried to defend the Goryeo and defeat Mongolia"s invasion.

한국인 직무 스트레스 측정도구의 개발 및 표준화

장세진,고상백,강동묵,김성아,강명근,이철갑,정진주,조정진,손미아,채창호,김정원,김정일,김형수,노상철,박재범,우종민,김수영,김정연,하미나,박정선,이경용,김형렬,공정옥,김인아,김정수,박준호,현숙정,손동국 大韓産業醫學會 2005 대한직업환경의학회지 Vol.17 No.4

Background and Purposes: Over the past three decades, numerous studies performed in Korea have reported that job stress is a determinant risk factor for chronic diseases and work disability. Every society has its own culture and occupational climate particular to their organizations, and hence experiences different occupational stress. An occupational stress measurement tool therefore needs to be developed to estimate it objectively. The purpose of this study is to develop and standardize the Korean Occupational Stress Scale (KOSS) which is considered to be unique and specific occupational stressors in Korean employees. Subjects and Methods: Data were obtained from the National Study for Development and Standardization of Occupational Stress (NSDSOS Project: 2002-2004). A total of 12,631 employees from a nationwide sample proportional to the Korean Standard Industrial Classification and the Korean Standard Occupational Classification were administered. The KOSS was developed for 2 years (2002-2004). In the first year, we collected 255 items from the most popular job stress measurement tools such as JCQ, ERI, NIOSH and OSI, and 44 items derived from the a qualitative study (depth interview). Forty-three items of KOSS, in the second year, were retained for use in the final version of the KOSS by using Delphi and factor analysis. Items were scored using conventional 1-2-3-4 Likert scores for the response categories. Results: We developed eight subscales by using factor analysis and validation process: physical environment (3 items), job demand (8 items), insufficient job control (5 items), interpersonal conflict (4 items), job insecurity (6 items), organizational system (7 items), lack of reward (6 items), and occupational climate (4 items). Together they explained 50.0% of total variance. Internal consistency alpha scores were ranged from 0.51 to 0.82. Twenty-four items of the short form of the KOSS (KOSS-SF) were also developed to estimate job stress in the work setting. Because the levels of the subscales of occupational stress were gender dependent, gender-specific standard norms for both the 43-item full version and the 24-item short form using a quartile for the subscales of KOSS were presented. Conclusion: The results of this study suggest that KOSS might be an appropriate measurement scale to estimate occupational stress of Korean employees. Further and more detailed study needs to be conducted to improve the validity of this scale.

A Patient with Ankylosing Spondylitis Treated with Acupotomy and Traditional Korean Medicine

Kim, Beom Seok,Kim, Jae Ik,Kim, Hyo Bin,Lee, Ye Ji,Sung, Ki Jung,Jeon, Ju Hyun,Kim, Eunseok,Kim, Young Il Korean AcupunctureMoxibustion Medicine Society 2019 Korean Journal of Acupuncture Vol.36 No.3

This case report relates to a 40-year old male patient diagnosed with ankylosing spondylitis who was treated with acupotomy and traditional Korean medicine. He showed a significant improvement in joint range of motion (ROM) in cervical and lumbar vertebrae, and in pain and functional disorder symptoms. The patient received acupotomy, acupuncture, pharmacopuncture, herbal medicine and physical therapy (November 26, 2018 to December 17, 2018). Joint ROM for cervical and lumbar vertebrae was measured, and the pain level was assessed using a numerical rating scale. The functional disorder and quality of life scales were also assessed using the Bath Ankylosing Spondylitis Functional Index, Bath Ankylosing Spondylitis Disease Activity Index, Korean Health Assessment Questionnaire, and Modified Health Assessment Questionnaire. After applying acupotomy and traditional Korean medicine, the patient exhibited increased joint ROM and reduced pain, also in conjunction with improved responses in functional disorder and quality of life.

Radiation-induced Pulmonary Toxicity and Related Risk Factors in Breast Cancer

Kim, Hak Jae,Jang, Won Il,Kim, Tae Jung,Kim, Jee Hyun,Kim, Sung Won,Moon, Sung Ho,Kim, Jae Sung,Kim, In Ah Korean Breast Cancer Society (KAMJE) 2009 Journal of breast cancer Vol.12 No.2

Hepatic venous pressure gradient can predict the development of hepatocellular carcinoma and hyponatremia in decompensated alcoholic cirrhosis

Kim, Moon Young,Baik, Soon Koo,Yea, Chang Jin,Lee, Il Young,Kim, Hye Jung,Park, Kyong Won,Kim, Hearn Kook,Suk, Ki Tae,Kim, Jae Woo,Kim, Hyun Soo,Kwon, Sang Ok,Cha, Seung Hwan,Kim, Young Ju,Koh, Sang B Lippincott Williams Wilkins, Inc. 2009 European journal of gastroenterology & hepatology Vol.21 No.11

OBJECTIVE: Portal hypertension is closely associated with serious complications of cirrhosis, which contribute to bad prognosis. Hepatocellular carcinoma (HCC) and low serum sodium (SNa) are manifestations of end-stage liver disease and are associated with poor survival in decompensated cirrhosis patients. We aimed to determine the relationship between hepatic venous pressure gradient (HVPG) and the development of HCC or low SNa in decompensated alcoholic cirrhosis patients. METHODS: Child-Pugh scores, Model for End-Stage Liver Disease scores, and HVPG at baseline, and the development of HCC or low SNa (SNa <130 mEq/l) during follow-up were analyzed prospectively in 170 patients with decompensated alcoholic cirrhosis from December 1999 to January 2008 (mean follow-up period of 33.9±27.9 months). The predictive value of different risk factors for the development of HCC and low SNa and survival were investigated. RESULTS: Twenty-four patients developed HCC during the follow-up period. In the multivariate analysis, only baseline HVPG greater than 15 mmHg was an independent predictive factor for the development of HCC (relative risk=1.128, P<0.05) and which showed a significantly shorter time for the development of HCC on the Kaplan–Meier analysis. Twenty patients developed low SNa during follow-up. Initial HVPG was also an independent predictive factor for the new development of low SNa in the multivariate analysis (relative risk=1.169, P<0.05) and which also showed significantly shorter times for the development of low SNa on the Kaplan–Meier analysis. CONCLUSION: In decompensated alcoholic cirrhosis, HVPG may be a useful predictive factor for the development of HCC and low SNa.