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중증 궤양성 대장염에서 치료 성적의 예측인자와 Cyclooxygenase - 2 발현과의 관계
박동일(Dong Il Park),김영호(Young Ho Kim),성인경(In Kyung Sung),이용육(Yong Wook Lee),이준행(Jun Haeng Lee),김지은(Jee Eun Kim),현재근(Jae Geun Hyun),장재권(Jae Kwon Jang),손희정(Hee Jung Son),이풍렬(Poong Lyul Rhee),김재준(Jae J . K 대한소화기학회 2001 대한소화기학회지 Vol.38 No.1
Background/Aims: Percutaneous endoscopic gastrostomy (PEG) has been widely performed for patients who require prolonged tube feeding support. A retrospective study was conducted to evaluate the complications of PEG and determine the predictors of wound infection. Methods: Medical records of 144 cases of PEG that was per- formed between January 1996 and June 2000 were reviewed to examine the types and frequency of complication, difference in wound infection rates according to age, sex, and underlying diseases. We also analyzed the effects of antibiotics prophylaxis on wound infection and the result of culture from wound infection site. Results: In 28 of 144 PEG cases (19.4%), several complications developed after procedure. Wound infection was the most common complication and occurred in 22 of 144 cases (15.3%) and Pseudomonas aeruginosa was the most common pathogenic microorganism. Other complications included bleeding from gastrostomy site, stomal leaks, and gastroesophageal reflux. There was no statistical difference in wound infection rates according to underlying diseases and antibiotics prophylaxis. However, wound infection developed more frequently in diabetes patients (p<0.05). Old age and underlying diabetes were predictors for developing wound infection after PEG in multiple logistic regression analysis. Conclusions: Old age and DM can be predictors of wound infection associated with PEG. (Korean J Gastroenterol 2001;38:23-28)
박동일 ( Dong Il Park ),안승섭 ( Seung Seop Ahn ),고병련 ( Byong Byeon Ko ),오영훈 ( Young Hun Oh ) 한국수처리학회 2015 한국수처리학회지 Vol.23 No.5
According to the analysis on previous studies of numerical modeling and evaluation of ground water effects, most of them focused on mediating variables, rather than a grid size. The first setting for modeling is a proper grid size of an area to analyze. Therefore, this study used the three-dimensional numerical analysis model MODFLOW to vary a grid size, to estimate an observation level and a calculation level, and to compare the characteristics of ground water. As a result, when the optimal mediating variable with the grid size of 50m×50m was estimated for the initial mediating variable, Mean error was 0.159, Mean absolute error 1.072, Root mean squared error 1.489. Therefore, the target area had applicability of numerical model. In the condition where the optimal mediating variable was fixed and a grid size varied, the model was applied. As a result, just as the value of observation level, the value of determination coefficient was 0.999. It indicated that mediating variable was more sensitive to ground water modeling than a grid size. Nevertheless, in the case of modeling for wells density area or for precision, each grid size was analyzed to be determined according to well in order for more accurate analysis. Therefore, it was found that it was necessary to set a proper grid size and assign each grid size to each well in order to increase accuracy of modeling.
혈관침범이 의심되는 췌장암 환자에서 절제 가능성과 생존율 분석
박동일(Dong Il Park),이종균(Jong Kyun Lee),김지은(Jee Eun Kim),현재근(Jae Geun Hyun),이규택(Kyu Taek Lee),이풍렬(Poong Lyul Rhee),김재준(Jae Jun Kim),고광철(Kwang Cheol Koh),백승운(Seung Woon Paik),이종철(Jong Chul Rhee),최규완(Kyoo 대한내과학회 2000 대한내과학회지 Vol.58 No.6
Background : One of the major limitations of curative resection in pancreatic cancer patients is local tumor extension to the mesenteric vessels. Thus, the purposes of our study were (1) to assess the clinical value of contrast enhanced spiral CT in predicting the resectability and survival of pancreatic cancer patients with suspicious vascular invasion and (2) to assess the influence of curative resection on survival in these patients.Methods : Forty cases of the pancreatic cancer patients who were suspected of having involvement of adjacent large vessels and subsequently underwent operation with curative intent were enrolled in this study. Resectability and survival were correlated with CT findings such as segment length, degree of encasement, type and number of vessel involved. Survival rate was compared between curative and palliative resection groups. And survival was also compared between resected and non-resected groups. Results : Of the 40 patients with adenocarcinoma of the pancreas, 14 patients had curative resections, and 26 patients had palliative resections. The probability of curative resection was higher in patients with segment length less than 2 cm, compared with those with more than 2 cm. However, there was no difference in survival between two groups. There were no differences of resectability and survival according to the degree of encasement, type and number of vessel involved. There were no difference in survival between curative and palliative resection groups, and between resected and non-resected groups. Conclusion : A survival benefit is not achieved by curative resection in pancreatic cancer patients with vascular invasion. So other non-operative treatments should be considered as effective tools prior to resection in these patients.(Korean J Med 58:651-656, 2000)
원발성 담즙성 경변증 16예의 임상상 : 단일 센터 경험
박동일(Dong Il Park),고광철(Kwang Cheol Koh),이준혁(Jun Hyek Lee),최문석(Moon Seok Choi),강태욱(Tae Wook Kang),문원(Won Moon),류민규(Min Kyoo Ryu),이용욱(Yong Wook Lee),김지은(Jee Eun Kim),현재근(Jae Geun Hyun),장재권(Jae Kwon Jang) 대한내과학회 2000 대한내과학회지 Vol.59 No.6
Background : Primary biliary cirrhosis (PBC) is a chronic cholestatic liver disease of unknown etiology. The disease is relatively common in western countries, but so far, only about 20 cases have been reported in Korea. Thus, the purpose of our prospective study was to evaluate the clinical characteristics of PBC in Korea. Methods : Between October 1994 and February 1999, 16 patients diagnosed as PBC at our department were enrolled in this study. We analyzed these patients for the distribution of age and sex, initial symptoms and signs, associated disorders, laboratory, endoscopic, and radiologic and histologic findings. Results : Of the 16 patients, the ratio of male to female was 1:7 and the average age was 57.5 years. Pruritus (37.5%) was the most frequent presenting symptom followed by xerostomia and xerophthalmia (12.5%), jaundice (6.3%), chronic fatigue (6.3%), melena (6.3%). Associated disorders were Sj gren's syndrome (25%), arthropathy (12.5%), Raynaud's phenomenon (6.3%) and diabetes (6.3%). Abnormalities of liver function were found frequently. Antimitochondrial antibody (100%), antinuclear antibody (31.25%) and rheumatoid factor (31.25%) were found. Long-term administration of UDCA improved both clinical and biochemical signs in most patients, however, 2 patients experienced exacerbation during UDCA therapy. Conclusions : We experienced 16 cases of PBC within a short period. It is expected that we can find these patients more frequently if we suspect this disease in patients with pruritus and unexplained obstructive pattern of liver function abnormality.(Korean. J. Med 59:634-640, 2000)