Hydrophobic Aminostyryl Quinolinium Dyes as New Fluorescent Stains for Proteins in Sodium Dodecyl Sulfate-polyacrylamide Gel

Sooyeon Hong,Seung Soo Yoon*,Chulhun Kang,Myungkoo Suh* 대한화학회 2004 Bulletin of the Korean Chemical Society Vol.25 No.3

식품의 건강함 정도가 기업 성과에 미치는 영향 : 한국 식품 기업 사례를 중심으로

서용원(Suh, Youngwon),이수현(Lee, Suhyeon),정수연(Jung, Sooyeon),정드림(Jung, Dream),윤원주(Yun, Wonjoo) 한국상품학회 2021 商品學硏究 Vol.39 No.4

본 연구는 식품의 건강함 정도를 정량화하고, 브랜드 매출 및 기업의 성과에 미치는 영향을 실증적으로 검증하고자 한다. 구체적인 연구 목표는 다음과 같다. 첫째, 한국 실정에 맞는 식품의 건강함 정도를 계량화한다. 둘째, 한국에서 판매중인 모든 가공식품에 식품의 건강함 정도를 적용하고자 한다. 셋째, 식품의 건강함 정도가 실제 기업성과와 연관이 있는지 살펴보고자 한다. 식품의 건강함 정도를 측정하기 위해 식품의약품안전처 제공 식품영양성분 데이터베이스에서 47,605개 제품의 영양성분데이터를 수집하였다. 실증분석을 위해 2011년부터 2019년까지 9년간 닐슨코리아 제공 식품 브랜드별 매출액 데이터와 2008년부터 2020년까지 13년간 기업의 재무 성과지표와 주가정보를 KIS-Value를 통해 수집하였다. 이 건강함 척도를 기준으로 High healthfulness, Low healthfulness 그룹으로 나누어 t-test 분석 결과, 식품의 건강함 정도가 높은 기업들이 낮은 기업들보다 브랜드 매출과 수익성 측면에서 부분적으로 긍정적인 성과를 보였고, 시장 가치의 경우에도 더 좋은 성과를 거두었다. 본 연구의 탐색적 분석과 실증분석 결과 및 전략적 제언을 통해 실무적 연관성을 극대화하고 관련 이론의 발전을 꾀하고자 한다. This study quantifies the overall healthfulness of food and empirically tests the relationship between healthfulness and firm performance. The research objectives are as follows: First, the authors present an improved overall healthfulness measure reflecting the circumstances in South Korea. Second, the overall healthfulness measure is applied to all processed foods available in South Korea. Third, the authors explore the relationship between healthfulness and firm performance including actual brand sales, ROA, and Tobin’s Q. To measure the overall healthfulness, the authors analyze nutritional content data of 47,605 products from the Ministry of Food and Drug Safety (MFDS). To empirically test the relationship, this study employs actual brand sales over a 9-year period (2011-2019) by Nielsen Korea and financial performance measures by KIS-Value. According to the results, companies with higher overall healthfulness showed greater brand sales and firm value than those with lower overall healthfulness. Finally, theoretical, managerial, and public policy implications will be discussed.

경찰공무원 정신건강 실태 및 정책 개선방안 연구

이지영(Jiyoung Lee),임재호(Jaeho Lim),서수연(Sooyeon Suh) 한국인사행정학회 2017 한국인사행정학회보 Vol.16 No.3

경찰공무원은 민원인과의 갈등, 각종 사고 및 폭력 현장에 대한 노출이 많은 직업 중 하나이다. 이로 인한 높은 직무 스트레스, 정신적 어려움과 트라우마는 즉각적이고 효과적인 치안 서비스에 방해로 작용하게 되고, 경찰 업무수행에 상당한 문제를 가져올 수 있다. 따라서 본 연구는 일선 경찰공무원의 정신건강과 관 련된 문제를 분석하는 것이 주요 목적이다. 이를 위해 서울시 한 경찰서의 경찰공무원 278명(평균 연령 45.27±9.00, 남성 88.5%)을 대상으로 양적 및 질적인 연구 방법론을 활용하여 6가지 문제 영역의 실태 조사를 하고, 1:1 면담을 통해 심층적인 원인과 이후 개선방안을 조사하고자 하였다. 연구 결과, 경찰공무원이 가장 흔히 경험하는 문제는 불면증이었다(52.5%). 이에 더해 73.4%는 본 연구에서 측정한 정신건강 영역 중 한 가지 이상 위험군에 해당하였으나 전문적인 치료 혹은 상담연계는 2.5%만 이어졌다. 이는 경찰공무원의 정신건강 문제에 개입이 필요하지만 상당한 장애물이 존재할 수 있다는 것을 시사한다. 따라서 본 연구는 이를 바탕으로 현행 정신건강 증진 정책을 검토하고 실질적인 정책 개선방안을 제안하였다. 나아가 매년 시행되고 있는 경찰공무원 심리안정 사업이 보다 효과적으로 안착되고 발전할 수 있는 방향성을 제시하고자 한다. Police officers are one of the occupations that are at highest risk for occupational stress, emotional distress, and trauma. Often times, such mental health issues interfere with the performance of police officers in their ability to effectively maintain public order. The purpose of this study was to understand the current mental health status of police officers utilizing both quantitative and qualitative methodology. Participants consisted of 278 police officers(mean age 45.27±9.00, males 88.5%) in Seoul. All participants completed self-report measures of the following domains: depression, suicide, stress, sleep, PTSD, and alcohol. Subsequently, a semi-structured interview was conducted to investigate reasons why police officers do not seek treatment, and recommendations to policies to improve mental health in police officers. The results showed most of police officers experienced insomnia(52.5%). Additionally, 73.4% of the sample reported having at least one at risk symptom of mental health problems. However only 2.5% agreed to seek treatment for these problems. These finding indicate that it is necessary to implement interventions to improve mental health of police officers, considering the obstacles. Thus, this study suggests that substantive and efficient policies of mental health in police officers are needed.

Cigarette Smoking in South Korea: A Narrative Review

Rebekah Gunter,Edwin Szeto,Se-Hoon Jeong,Sooyeon (Aly) Suh,Andrew J. Waters 대한가정의학회 2020 Korean Journal of Family Medicine Vol.41 No.1

Although the prevalence of cigarette smoking has declined in Western countries over the past few decades, a comparable decline among males has not been observed in Asian countries, especially in South Korea, where approximately 40%–50% of men and 4%–8% of women have been identified as smokers, and there is a pressing need to understand the background of cigarette smoking in these populations. The present study is a narrative review of the research literature on cigarette smoking in South Korea. First, we describe the social, economic, and cultural factors that impact cigarette smoking in South Korea. The paper also reviews the available peer-reviewed literature comprising observational studies and interventional studies, including randomized controlled trials. The extant literature on smoking in Korean Americans is also reviewed. Cigarette smoking in South Korea has been relatively understudied, and this review identifies priority areas for future research, including the use of mobile interventions.

Metformin ameliorates olanzapine-induced disturbances in POMC neuron number, axonal projection, and hypothalamic leptin resistance

( Jaedeok Kim ),( Nayoung Lee ),( Sang Bum Suh ),( Sooyeon Jang ),( Saeha Kim ),( Dong-gyu Kim ),( Jong Kook Park ),( Keun-wook Lee ),( Soo Young Choi ),( Chan Hee Lee ) 생화학분자생물학회 2022 BMB Reports Vol.55 No.6

Antipsychotics have been widely accepted as a treatment of choice for psychiatric illnesses such as schizophrenia. While atypical antipsychotics such as aripiprazole are not associated with obesity and diabetes, olanzapine is still widely used based on the anticipation that it is more effective in treating severe schizophrenia than aripiprazole, despite its metabolic side effects. To address metabolic problems, metformin is widely prescribed. Hypothalamic proopiomelanocortin (POMC) neurons have been identified as the main regulator of metabolism and energy expenditure. Although the relation between POMC neurons and metabolic disorders is well established, little is known about the effects of olanzapine and metformin on hypothalamic POMC neurons. In the present study, we investigated the effect of olanzapine and metformin on the hypothalamic POMC neurons in female mice. Olanzapine administration for 5 days significantly decreased Pomc mRNA expression, POMC neuron numbers, POMC projections, and induced leptin resistance before the onset of obesity. It was also observed that coadministration of metformin with olanzapine not only increased POMC neuron numbers and projections but also improved the leptin response of POMC neurons in the olanzapine-treated female mice. These findings suggest that olanzapine-induced hypothalamic POMC neuron abnormality and leptin resistance, which can be ameliorated by metformin administration, are the possible causes of subsequent hyperphagia. [BMB Reports 2022; 55(6): 293-298]

Improvement of Vase Life and Flowering Quality of Cut Freesia (Freesia refracta) ‘Gold Rich’ by Combination of Pretreatments and Holding Solutions

Haejo Yang,Youn Jung Choi,Jae A Jung,Jung-Nam Suh,Sooyeon Lim,Ji Weon Choi,Yoonpyo Hong,Il Sheob Shin 한국화훼학회 2020 화훼연구 Vol.28 No.3

본 연구는 몇가지 전처리제 및 보존용액 처리가 국내 육성 절화 프리지아 ‘Gold Rich’의 수확후 절화수명과 개화 품질에 미치는 영향을 구명하고자 수행하였다. 10% sucrose, 200mg・L-1 Al2(SO4)3, 200mg・L-1 GA3, 150mg・L-1 citric acid가 혼용된 전처리 용액에서 절화 관상 기간 동안 수분 흡수량과 생체중은 유의적으로 증가한 것으로 조사되었지만 절화수명에는 큰 영향을 미치지 않았다. 보존용액으로 5% sucrose와 살균제인 300mg・L-1 8-HQ를 혼용 처리하였을 때 절화수명 연장(1일 이상), 높은 개화율(82.3~89.1%) 및 만개율(71.5~84.2%) 등의 개화 품질이 향상되었다. 이러한 결과들을 통해 10% sucrose, 200mg・L-1 Al2(SO4)3, 200mg・L-1 GA3, 150mg・L-1 citric acid를 혼합한 전처리제와 5% sucrose, 300mg・L-1 8-HQ를 혼합한 보존용액 처리는 절화수명 연장, 개화율 및 만개율 증가에 효과적일 것이라고 판단된다. 특히, sucrose가 포함된 보존용액은 절화 프리지아 ‘Gold Rich’ 의 상품성 향상에 있어 매우 유용할 것이다. This experiment was conducted to investigate the effects of pretreatment and holding solutions on the vase life and quality of cut freesia ‘Gold Rich’ flowers. The pretreatment solution contained 10% sucrose, 200 mg・L-1 Al2(SO4)3, 200 mg・L-1 GA3, and 150 mg・L-1 citric acid. This solution significantly increased the water uptake and fresh weight of the flowers, but did not significantly affect vase life. The holding solution contained 5% sucrose and 300 mg・L-1 8-HQ significantly improved the flowering quality of the plants, extended vase life (by 1 day or more), resulted in a high percentage of flowers (82 - 89%) and a high percentage of full blooms (71 - 84%). These results suggest that a combination of the pretreatment solution and the holding solution could effectively increase the flowering percentage, the full bloom percentage, and the vase life. In particular, treatment of a holding solution containing sucrose will be very useful to improve the commerciality of the cut freesia ‘Gold Rich’.

The Relationship between Mother’s Smartphone Addiction and Children’s Smartphone Usage

Bomi Kim,So ra Han,Eun-Jin Park,Heejeong Yoo,Sooyeon Suh,Yunmi Shin 대한신경정신의학회 2021 PSYCHIATRY INVESTIGATION Vol.18 No.2

Objective As smartphone use is becoming more common, the age of initial exposure to devices is becoming younger. Young children’s screen use is influenced by various factors; it is more directly dependent on family environment than school-aged children. Our study aimed to examine the effect of mother’s smartphone addition on their child’s smartphone use. Methods Participants were from the Kids Cohort for Understanding of internet addiction Risk factors in early childhood (K-CURE) study. Adult smartphone addiction self-diagnosis scale was used to evaluate smartphone addiction degree of mother. Child’s smartphone use was assessed by parental questionnaire. Using logistic regression analysis, we examine the association between mother’s smartphone addiction and child’s smartphone use. Results After adjusting for other factors, mother’s smartphone addiction is related with early smartphone exposure of children. Highrisk group’s children was exposed to smartphone earlier than low risk group (adjusted OR, 0.418; p=0.021). Contrary to expectation, there is no correlation between mother’s smartphone addiction and child’s smartphone use time. Conclusion Our study explain that mother’s smartphone addiction can affect early smartphone exposure on children. Based on our findings, further study might explore the effect of early smartphone exposure on children.

Sleep Characteristics and Risk Factors of Korean Esports Athletes: An Exploratory Study

이상하,Bonnar Daniel,Kim Yeji,Lee Yoojin,Lee Sunkyung,Gradisar Michael,Suh Sooyeon 대한수면학회 2020 sleep medicine research Vol.11 No.2

Background and ObjectiveaaAlthough sleep is a potentially important determinant of performance in esports, there have been no published data on the sleep behavior of professional esports athletes. The aim of this study is to investigate sleep aspects and sleep risk factors in esports athletes. MethodsaaThirty-four esports athletes were compared with 21 nonathletes from the general population to assess their sleep patterns and mood. Study 1 is a quantitative study with a 2-week observation period of sleep that was performed after evaluating insomnia severity, daytime sleepiness, sleep knowledge, and mood state. During the sleep observation period, participants recorded sleep diaries. In study 2, qualitative research was conducted with in-depth interviews from 6 participants. ResultsaaThe esports athlete group reported significantly delayed sleep phase compared to the nonathlete group (d = 2.10 hours, p < 0.001). The esports athlete group reported significantly lower sleep quality and scores for feeling refreshed upon awakening, higher depression scores and significantly higher proportion of individuals with clinical symptoms of depression compared to the nonathlete group (ps < 0.01). In study 2, six themes emerged from the interviews: sleep risk factors, sleep protective factors, lifestyle, stressors, organizational management, and demands for sleep/ psychological intervention. ConclusionsaaThe professional esports athletes showed more depressed mood and more delayed sleep phase compared to the non-athletes. A wide range of interventions tailored to esports athletes should be developed and implemented on both individual and organizational levels.

Effects of Depression and Resilience of Public Workers on Work-related Stress and Anxiety in Response to the COVID-19 Pandemic

Ju Gawon,Lee Jeonghwan,Ahn Myung Hee,Lee Joohee,Kim Eun Jeong,Suh Sooyeon,Chung Seockhoon 대한의학회 2021 Journal of Korean medical science Vol.36 No.36

Background: This study explored the clinical variables related to public workers' stress and anxiety regarding the viral epidemic, and the mediating effect of resilience on the relationship between their depression and anxiety in response to coronavirus disease 2019 (COVID-19) pandemic. Methods: A total of 938 public workers answered anonymous questionnaires in May 2020. The survey included rating scales such as the Stress and Anxiety to Viral Epidemics-9 (SAVE9), Patients Health Questionnaire-9 (PHQ-9), Generalized Anxiety Disorder-7 (GAD-7), and Connor-Davidson Resilience Scale 2 items (CD-RISC 2), and subjects also answered whether they were employed in COVID-19 related fields. Results: Married, female, junior, public workers reported a higher level of stress and anxiety in response to the viral epidemic. Furthermore, high levels of stress and anxiety toward the epidemic are defined by high PHQ-9, high GAD-7, and low CD-RISC 2 scores. It could also be seen that resilience mediated the effect of depression in public workers and their stress and anxiety levels toward the epidemic. Conclusion: It is important to reduce the psychological burden of public workers and manage their mental health to help them cope with the epidemic wisely and efficiently. Among many mental health factors, psychological resilience represents an essential target for psychological intervention among public workers.

Obstructive Sleep Apnea as a Risk Factor for Stroke

( Eo Rin Cho ),( Hyun Kim ),( Hyung Suk Seo ),( Sooyeon Suh ),( Seung Ku Lee ),( Seung Hyeun Lee ),( Je Hyeong Kim ),( Chol Shin ) 대한결핵 및 호흡기학회 2012 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.114 No.0

Previous studies have suggested that obstructive sleep apnea (OSA) may be a risk factor for stroke. In this study, we assessed that OSA is an independent risk factor of stroke in the general population, and in a non-obese population. The study recruited a total of 746 participants (252 men and 494 women) aged 50-79 years as part of the Korean Genome and Epidemiology Study (KoGES), and they underwent polysomnography, brain magnetic resonance imaging, and health screening examinations. Stroke was assessed by subtypes and brain regions, and lacunar infarction represented lesions less than 15 mm in size in the penetrating arteries. Moderate-severe OSA was determined by apnea-hypopnea index ≥15. Results indicated that 12.06% had Moderate-se-vere OSA, 7.64% of participants had stroke, and 4.96% had lacunar infarction. Moderate-severe OSA was positively associated with stroke (OR, 2.47; 95% CI, 1.01-6.02) and lacunar infarction (OR, 3.64; 95% CI, 1.34-9.92) in age ≥65 compared those with non-OSA. Additionally, in the basal ganglia, OSA was associated with an increase in the odds for stroke and lacunar infarction in all age groups and especially in the ≥65 age group. In the non-obese participants, OSA was also positively asso-ciated with stroke in ≥65 age group, and lacunar infarction in all age groups and especially in the ≥65 age group. There was also positive association with the basal ganglia. Moderate-severe OSA was positively associated with stroke and lacunar infarction in the elderly. Treatment of OSA may reduce prevalence and progression of stroke.