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발전기 고정자 권선용 마이카/에폭시 수지의 표면 및 구조분석
이상교,심재선,정의남,송우창,박하용,심상흥,임윤희,박종국,심낙순 三陟大學校 1998 論文集 Vol.31 No.1
The purpose of this study is to determine the ageing mechanism of Mica/Epoxy composite material for large generator stator windings in order to estimate remaining life of generator. X-ray analysis is performed to investigate the position and structure of mica crystal in insulation materials. The phase change of aged and sound specimen under each atmosphere isn't observed. Surface analysis of insulation materials by optical microscope also show that the sound and aged specimen, sliding phenomenon by shear and thermal stress is observed both interface between mica and epoxy.
양측성 고정원을 이용한 이소 맹출의 치료에 대한 증례 보고
선예경,심연수,안성인 大韓小兒齒科學會 1999 大韓小兒齒科學會誌 Vol.26 No.2
제 1 대구치의 이소 맹출이란 제 1 대구치가 비정상적인 맹출 경로를 취해 제 2 유구치의 비정상적인 조기 흡수를 일으키는 경우를 뜻한다. 비가역적 이소 맹출의 경우 제 2 유구치의 조기상실은 공간 상실, 제 1 대구치의 근심 경사, 제 2 소구치의 함몰, 총생과 대합치의 과맹출등을 야기 시킨다. 치료의 주목적은 (1) 제 2 유구치의 조기 상실을 막아 공간 유지의 역할을 하게하고 (2) 상실된 치열장을 회복해 제 2 소구치의 정상적인 맹출을 돕는 것이다. 치료 방법은 제 1 대구치의 맹출 정도, 제 1 대구치의 위치 변화, 제 1 대구치가 걸려있는 제 2 유구치의 enamel ledge 양, 제 2 유구치의 동요도, 동통이나 염증의 유무에 의해 결정된다. 제 1 대구치의 근심 경사의 치료에 사용되는 대부분의 편측성 장치는 결과적으로 공간 상실을 증가시키는 힘을 가하게 된다. 따라서 고정원의 보강을 위해 holding arch와 같은 양측성 고정원의 사용이 추천되고 있다. 본 증례 보고는 삼성 서울 병원을 내원한 환아 중 제 1 대구치의 비가역적 이소 맹출로 제 2유구치의 치근 흡수와 동요도 증가를 보이는 환아에서 양측성 고정원을 이용한 장치를 사용해 제 2 소구치의 정상적인 맹출에 필요한 충분한 공간을 유지할 수 있었기에 이에 보고하는 바이다. Ectopic eruption of the first permanent molar means the first permanent molar assumes an atypical path of eruption resulting in premature atypical resorption of the second primary molar. If the reversible eruption does not occur, early loss of the second primary molars results in space loss, mesial tipping of the first permanent molar, impaction of the second premolar, buccal segment crowding and overeruption of opposing tooth. The main objectives of treatment are (1) to prevent loss of the second deciduous molars so it can continue to serve as a space maintainer and (2) to regain lost arch length, allowing the second premolar to erupt into normal position. The optimal treatment approach depends on a number of factors including the clinical eruption status of/6/, the change in position of/6/, the amount of enamel ledge of/E/ entrapping/6/, the mobility of/E/, and the presence of pain of infection. Unilateral appliance to correct the mesial angulation of ectopic permanent first molars, as in the majority of the appliance designs, would produce a resulotant force that would further enhance the space loss. A bilateral support similar to the holding arch design is recommended to maximize the anchorage. These case reports present the successful result of preserving space for the second premolar in treatment of ectopic eruption of the first permanent molar using Halterman appliance with bilateral anchorage on patients visting department of pediatric dentistry in Samsung Medical Center.
돼지 신장세포(PK15)의 이종이식 거부반응에 대한 재조합 IL-18의 영향
최연실,김은미,김영관,박상연,심정현,윤도영,강형식,명평근 충남대학교 형질전환복제돼지연구센터 2004 논문집 Vol. No.8
Various cytokines including IL-1β, IL-2, IL-4, IL-10, IL-12p40, IFN-r, and TNF-α have been recently reported to play important roles in both host and donor cell activations during xenotransplantation. Interleukin (IL)-18, a proinflammatory cytokine, can induce IL-4 and IL-13 production in T cells, NK cells, B cells, mast cells, and basophils. IL-18 has the capacity to stimulate innate immunity and both Th1-and Th2- mediated responses, but little is known to involve in the xenograft rejection. In order to investigate the role of IL-18 in xenograft rejection, we transplanted the pig kidney (PK15) cells to C57BL/6 mouse with or without intraperitoneal injection of mouse recombinatant IL-18, It was analyzed the population of T cell, B cell and NK cell in the mice transplanted with PK 15 cells and recombinant IL-18 by flow cytometry. We found that splenic CD3+ T cells were increased in mice injected PKl5 cells with recombinant IL-18. These results suggest that recombinant IL-18 is critical in the xenograft rejection by increasing T cell population of the recipients.
돼지 신장세포(PK15)의 이종이식 거부반응에 대한 재조합 IL-18의 영향
최연실,김은미,김영관,박상연,심정현,윤도영,강형식,명평근 충남대학교 생물공학연구소 2004 생물공학연구지 Vol.10 No.1
Various cytokines including IL-1β, IL-2, IL-4, IL-10, IL-12p40, IFN-γ, and TNF-α have been recently reported to play important roles in both host and donor cell activations during xenotransplantation. Interleukin (IL)-18, a proinflammatory cytokine, can induce IL-4 and IL-13 production in T cells, NK cells, B cells, mast cells, and basophils. IL-18 has the capacity to stimulate innate immunity and both Th1-and Th2- mediated responses, but little is known to involve in the xenograft rejection. In order to investigate the role of IL-18 in xenograft rejection, we transplanted the pig kidney (PK15) cells to C57BL/6 mouse with or without intraperitoneal injection of mouse recombinatant IL-18. It was analyzed the population of T cell, B cell and NK cell in the mice transplanted with PK 15 cells and recombinant IL-18 by flow cytometry. We found that splenic CD3+ T cells were increased in mice injected PK15 cells with recombinant IL-18. These results suggest that recombinant IL-18 is critical in the xenograft rejection by increasing T cell population of the recipients.
Notes : Culture Conditions Affecting the Optimal Mycelial Growth of Cystoderma ami anthinum
( Sung Mi Shim ),( Yun Hee Oh ),( Kyung Rim Lee ),( Seong Hwan Kim ),( Kyung Hoan Im ),( Jung Wan Kim ),( U Youn Lee ),( Jae Ouk Shim ),( Mi Ja Shim ),( Min Woong Lee ),( Hyeon Su Ro ),( Hyun Sook Lee 한국균학회 2005 Mycobiology Vol.33 No.1
Recent Advances in Management of Laryngeal Cancer
Youn Sang Shim 대한암학회 2004 Cancer Research and Treatment Vol.36 No.1
Laryngeal cancers account for approximately 1.5% (1~2%) of the total cancers in Korea, and 30% of all head and neck cancers, not including thyroid cancer. Early laryngeal cancer is treated by operation, including transoral laser excision or radiotherapy. Advanced laryngeal cancer has been treated with mutilating operations, such as a total laryngectomy. However, a laryngeal preserving approach, which can improve the quality of life, has recently been tried with advanced laryngeal cancer.(Cancer Res Treat. 2004;36:13-18)
Carbonylation of 1-Bromo-2,6-bis(bromomethyl)benzene Catalyzed by Cobalt Carbonyl
Sang Chul Shim,Shin Ae Chae,Dong Yeob Lee,Young Zoo Youn,Jae Goo Shim,Chil Hoon Doh Korean Chemical Society 1993 Bulletin of the Korean Chemical Society Vol.14 No.4
Dialkyl 1-bromobenzene-2,6-diacetates were easily prepared by the carbonylation of the moiety of benzylic bromide in 1-bromo-2,6-bis(bromomethyl)benzene with alcohol in the presence of NaOAc< ${\cdot}$3H$_2$O and a catalytic amount of Co$_2$(CO)$_8$under the atmospheric pressure of carbon monoxide at room temperature in excellent yield. Alkyl 2,6-bis(alkoxymethyl)benzoates were obtained by the carbonylation of the moiety of aryl bromide in 1-bromo-2,6-bis(alkoxymethyl)-benzene, which derived from 1-bromo-2,6-bis(bromomethyl)benzene, alcohol, NaOR, and CH$_3$I under the same conditions. Alkyl 2,6-bis(carboxymethyl)benzoate was also obtained in a trace amount for 24 hrs at room temperature.