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      • KCI등재후보

        예방위주의 계속구강건강관리 제도의 운영사례에 대한 분석 연구 : 16세 이하 연령층을 대상으로

        원준영,신승철,서현석,류현 대한구강보건학회 2003 大韓口腔保健學會誌 Vol.27 No.3

        The purpose of this study was to obtain database for developing a model of incremental dental care system in Korea. The author conducted the incremental dental care for 232 persons during one year in personal dental hospital. The data was analyzed improvement of oral health conditions during initial stage and 1st incremental care stage, and required cost during one year. The results were as follows ; 1. Active caries free rate was increased from 75.43% to 94.83% during incremental dental care. 2. The mean care time was estimated 486.1 minutes per one person. The dental chair-time for incremental dental care was 314.9 minutes and the indirect required time was 171.2 minutes. 3. The mean care cost of incremental dental care was estimated 413,159 Won based on customary fee and 284,576 Won based on relative value scale, 278,521 Won based on labor cost and clinic operating cost. 4. The proper incremental dental care cost of the first year until highschool student was estimated about 280,000 Won, and the cost seemed to be reduced from second year. 5. It is suggested that incremental dental care program in personal dental clinic is effective means of improving oral health and it is recommended to extend the incremental dental care program.

      • SCISCIESCOPUS

        Photonic Crystals: Integration of Colloidal Photonic Crystals toward Miniaturized Spectrometers (Adv. Mater. 9/2010)

        Kim, Shin-Hyun,Park, Hyo Sung,Choi, Jae Hoon,Shim, Jae Won,Yang, Seung-Man WILEY-VCH Verlag 2010 Advanced materials Vol.22 No.9

        <B>Graphic Abstract</B> <P>The cover shows a schematic illustration of patterned colloidal photonic crystals with different bandgap positions. When an unknown light source impinges on the patterned photonic crystals, the light information can be identified from the reflection intensity profile of the constituent photonic crystals. The two optical microscopy images and background image display integrated photonic crystals with 20 different bandgaps spanning the entire visible range, and the SEM image shows the cross-section of the photonic crystal stripes, as reported by Shin-Hyun Kim, Seung-Man Yang, and co-workers on p. 946. <img src='wiley_img_2010/09359648-2010-22-9-ADMA201090022-content.gif' alt='wiley_img_2010/09359648-2010-22-9-ADMA201090022-content'> </P>

      • KCI등재후보

        아미노글리코사이드 사용제한에 따른 병원성 균혈증 유발 그람음성간균의 내성변화 및 임상적 의의

        오종택,김신우,손종원,도병훈,한승우,신병철,박지현,이종명,김능수 대한감염학회 2003 감염과 화학요법 Vol.35 No.4

        목적 : 항균제 오남용으로 인한 내성균의 출현, 약물부작용의 발생 및 약제 비용의 증가는 환자 개인뿐만 아니라 사회적으로 문제가 되고 있다. 본 연구는 항생제의 오남용을 막기 위한 제도의 일환으로 시행한 아미노글리코사이드 사용 제한정책의 비용 효과적인 측면을 조사하고 그람음성간균에 의해 병원성 균혈증이 발생한 환자들을 대상으로 이 정책이 항생제 내성률과 환자 사망률에 미치는 영향을 연구하였다. 방법 : 930병상 규모의 3차 병원인 일개 대학병원에서 아미노글리코사이드 사용제한정책이 시행된 직후인 2002년 3월에서 9월 사이에 그람음성간균(Acinetobacter baumannii, Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli, Enterobacter cloacae, Enterobacter aerogenes, Serratia marcescens, Stenotrophomonas maltophilia, Burkholderia cepacia)에 의해 발생한 병원성 균혈증 환자 60명(실험군)과, 이 정책이 시행되기 전에 입원한 환자들 중 균주별로 같은 수만큼 선별한 병원성 균혈증 환자 60명(대조군)의 의무기록을 후향적으로 조사하였다. 결과 : 아미노글리코사이드 사용제한정책이 시행된 시기인 2002년 3월에서 9월 사이에 처방된 아미노글리코사이드 사용량 및 비용을 이 정책이 시행되기 전인 2001년 3월에서 9월 사이와 비교한 결과, 아미노글리코사이드의 사용량(antimicrobial utilization density)은 사용제한 후 225.2에서 130.3으로 42% 감소하였고 약제 비용은 44% 감소하였다. 아미노글리코사이드 사용제한 후 병원성 균혈증을 유발한 그람 음성간균의 이 항생제에 대한 내성률은 유의한 변화를 보이지 않았으며 균혈증과 직접 연관된 사망률도 환자의 나이, 성별, 기저질환 및 원발병소 등을 보정할 경우 유의한 차이를 보이지 않았다(40.4% vs. 24.1%, P=0.11). 결론 : 아미노글리코사이드를 5일을 초과한 사용 시 감염전문가의 사전 승인을 필요로 하는 사용제한정책은 아미노글리코사이드의 사용량과 비용을 유의하게 감소시켰다. 또한 이 정책 시행 후 그람음성간균에 의한 균혈증 환자에서 균혈증으로 인한 사망률과 아미노글리코사이드에 대한 내성률은 유의한 차이가 없었다. Objective : To evaluate the effects of an aminoglycoside restriction policy on expenditures for aminoglycosides, antimicrobial resistance rates and clinical outcome of nosocomial bacteremia caused by Gram-negative bacilli (GNB). Methods : Starting in February, 2002, a prior consultation with an infectious disease specialist for using aminoglycoside antibiotics over 5 days was required in a 930-bed university hospital. In retrospective analysis of medical records 7 months after initiation of the aminoglycoside restriction policy, sixty cases of clinically relevant nosocomial bacteremia caused by GNB were found. These bacteremic patients were compared with sixty, species-matched, control patients with nosocomial Gramnegative bacteremia before the policy for total expenditures for aminoglycosides, susceptibility to antibiotics and clinical outcomes of bacteremia. Results : During the same period of 7 months before and after the restriction policy, total expenditures for aminoglycosides decreased by 44% in cost (from 465,030,841 Won to 259,618,337 Won) and the antimicrobial utilization density of aminoglycosides decreased by 42% (from 225,2 to 130.3). On the other hand, the patterns of antibiotic susceptibility and bacteremia-related in-hospital mortality rates after the policy did not show a significant change, compared with those before the policy. Conclusion : Antibiotic restrictions are among the most popular methods to diminish the practice of antibiotic overuse in hospitals. In this study, requirement for prior approval of aminoglycoside use over 5 days led to a significant decrease in the amount and cost of total aminoglycosides without a significant change in susceptibility patterns and bacteremia-related mortality rates.

      • 고주파수대역에 적용되는 Fe-( BN, Si₃N₄)박막의 미세구조와 자기적특성에 관한 연구

        申東勳,張勝彦,李宰源,南勝義 弘益大學校 科學技術硏究所 1997 科學技術硏究論文集 Vol.8 No.-

        We have investigated the magnetic properties of FeBN thin films deposited by using RF magnetron sputtering and Fe-BN composite target. It was investigated that the area fraction of BN chips on the Fe target and partial pressure of nitrogen was the main factors influencing the soft magnetic properties and resistivity of FeBN thin film. The low addition of N₂increases significantly the soft magnetic properties and electrical resistivity. The good soft magnetic properties are obtained at N₂partial pressure of 5%, but futher increase in N₂ partial pressure degrade the soft magnetic properties due to formation of nitrides such as Fe₄N, Fe₂∼₃N. In a sputtering process, as the area fraction of BN increases, FeBN thin films fabricated at the area fraction of 0.25 exhibt soft magnetic properties (Bs∼17kG, Hc∼10e, μ∼1000).

      • 미역취속 식물 정유의 종간 비교연구

        신승원 德成女子大學校 藥學硏究所 1996 藥學論文誌 Vol.7 No.1

        The composition of essential oils from Solidago species, S. canadensis, S. Virgaurea var. gigantes(cultivated and wild), were compared. The oils were analysed by gas chromatography and mass spectrometry.

      • KCI등재후보
      • 속단류의 성분 연구(1)

        신승원,오현경 德成女子大學校 藥學硏究所 1996 藥學論文誌 Vol.7 No.1

        The saponin fraction of Dipsacus asper Wall. was analysed. By utilizing silicagel column chromatography, 3-O-α-L-arabinopyranosyl hedragenin 28-O-β-D-glucopyranosyl (1-6)-β-D-glucopyranoside (akebia saponin D) and one triterpene compound were isolated from saponin fraction. Analgesic effect of the isolated saponin was recognized by the hot plate method and acetic acid stimulating method in mice.

      • Push-Pull Converter에 의한 대체에너지 발전시스템에 관한 연구

        申明澈,元忠淵,梁承浩,金學成 成均館大學校 科學技術硏究所 1990 論文集 Vol.41 No.1

        대출력범위의 DC-DC 컨버어터는 가변 저입력과 일정한 고출력 전압의 특성을 가지고 있다. 1KW push-pull 컨버어터 시스템이 실험을 위하여 제작되었다. 이 컨버어터는 25KHz의 내부 주파수를 가진 1KW의 전력을 처리한다. 이 컨버어터는 종래의 전력레벨 컨버어터에 스위칭 레귤레이터의 장점을 살린 것을 의미한다. 고주파 스위칭의 사용으로 DC-DC컨버어터의 크기와 중량을 감소시키게 되었다. 이러한 감소는 주파수가 증가함에 따라 필커값과 변압기의 크기가 감소하기 때문에 일어난다. 그러므로 저자는 고주파 변압기와 출력필터의 설계기준을 언급하였다. 마지막으로 연료전지 및 태양전지 발전시스템이 제시되었다. In this paper, a DC-DC converter for multikilowatt power level is described which has the characteristics of variable low input voltage and constant high output voltage. An 1KW push-pull converter system was constructed for experimentation. This converter processes 1KW power with an internal freqency of 25KHZ, which means to turn the merits of the switching regulator to the conventional power level converters. The use of high-frequency switching allows the DC-DC converter designer to reduce the size and weight of the DC-DC converter significantly. This reduction occurs because of filter component value and transformer size decrease with increasing frequency. Therefore, the authors in this paper the design criterion of the high frequency transformer and output filter was mentioned. Finally, applications for an inverter used in a fuel cell generation and solar cell generation system are presented.

      • 유산균의 배양 및 건조조건에 관한 연구 : 제1보 유산균의 배양조건에 관한 연구 partⅠ.Optimum Cultural Conditions of Lactic Acid Bacteria

        신원철,윤주천,김갑수,최승락,이근억,유주현 江原大學校 産業科學硏究所 1981 産業技術硏究 Vol.1 No.-

        In order to use as a starter after drying, optimum growth conditions of Str. thermophilus and L. bulgaricus were investigated. The results were as follows. The growth of Str. thermophilus was reached at stationary phase after 12 hours incubation and L. bulgaricus was after 6 hours. Str. thermophilus was grown well, in the medium containing 10% of skim milk, 2%5 of sucrose, 0.1% of KCl and 0.015%(v./v.) of soy-sauce. In the case of L. bulgaricus, 10% of skim milk, 2% of glucose, 0.5% of bacto-peptone, 0.1% of K₂HPO₄ and 0.02% of pyridoxine was suitable for the maximum growth.

      • 영구 심박동기 삽입 후에 발생한 우심실 천공 1례

        신원용,이승진,진동규 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

        Myocardial perforation is a rare complication after pacemaker implantation. We experienced the right ventricular perforation during implantation of a transvenous pacing electrode. The patient was 83-year-old woman who had permanent pacemaker(VDD) for 2:1 AV block. After insertion of a permanent pacemaker, she was pale and blood pressure, 80/50mmHg. An echocardiography revealed a moderate pericardial effusion without signs of cardiac tamponade. At serial echocardiography, pericardial effusion was decreased. She was discharged uneventfully.

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