심박수와 환기량을 이용한 최대산소섭취량 추정연구

김학렬,노성규,손태열,강인섭 龍仁大學校 體育科學硏究所 1991 體育科學硏究論叢 Vol.1 No.1

Direct measurement of oxygen uptake(V O₂??) is used to standard index of cardiorespiratory fitness, but is practical only in a laboratory setting. The purpose of this paper is presented assessing formular of V O₂?? with measured heart rate and ventilation as the independent variables and with directly measured V O₂?? as the dependent variables. Twenty males with college hand ball players volunteered to exercise on a bicycle ergometer by 2-min incremental load exercise. Incremented bicycle ergometer test was used to measure maximal values of metabolic variables. To calculated assessing formular of V O₂??, It was using linear regression and multiple linear regression. The conclusion were as follows : 1. Correlation Coefficient of heart rate and ventilation, oxygen uptake and ventilation, oxygen uptake and heart rate were presented r=0.918, r=0.936, r=0.930, respectively. also, multiple regression equation derived from data of the test group were; V O₂??(ml/kg/min)=HR(0.151)+VE-BTPS(0.012)-4.04…………(1) R²=0.9079 2. Linear regression of heart rate and oxygen uptake were: V O₂??(ml/kg/min)=HR(0.312)-14.03……………(2) R²=0.8654 3. Linear regression of ventilation and oxygen uptake were: V O₂??(ml/kg/min)=VE-BTPS(0.022)+6.997………(3) R²=0.8760 4. It was calculated more V O₂?? by using multiple linear regression considered two variables than assessing equation of V O₂?? with heart rate or ventilation.

의학 영상 저장 전송 시스템에 대한 연구 : 요구사항 및 사례연구를 중심으로 Requirements and Case Studies

이상학,전용희 대구효성가톨릭대학교 1998 연구논문집 Vol.57 No.2

The concept of Picture Archiving and Communication System(PACS) was originatted in radiology. The PACS is a medical imaging storage and dilivery system. The goal of PACS is to develop computer hardware and software which would enable electronic access, storage, transmission, and display of patient data and images. Installation of PACS in an existing hospital involves many technical and budget problems. Therefore, we need to study technical requirements which are necessary to implement PACS. According to the development of both computer and communication technologies, the introduction of PACS in domestic hospitals is becoming a reality and even appears as a vital component for the hospital information system. Therefore, the discussion and consideration on PACS before the installation inan existing hospital will be a real matter in the near future. Accordingly, we have defined general technical requirements for PACS in terms of hardware components required, imaging acquisition, media storage, compression/decompression, user interface, communication networks etc. Recent technology trends and case studies are also included. This basic study will be used for further study of PACS especially in terms of technical requirements for multimedia medical imaging storage, retrieval, and transmission on ATM networks.

양측 주관절 골관절염 후에 발생한 양측 척골신경 지연마비 1례 보고

이성태,안의환,이상학 건국대학교 의과학연구소 1996 건국의과학학술지 Vol.5 No.-

Tardy ulnar nerve palsy typically results from lateral condylar fracture of the humerus during periods of growth. There are many other causes inculding osteoarthritis of the elbow joint, medial epicondylar fracture of the humerus, recurrent dislocation of the ulnar nerve, and ganglion. We report a case of bilateral tardy ulnar nerve palsy resulting from osteoarthritis of both elbow joints in a 54-year-old male driver, who underwent anterior transposition of the ulnar nerve at the elbow joints.

치근단 병소의 임상적 연구

김상우,우순섭,유임학,이영수,심광섭 대한악안면성형재건외과학회 2001 Maxillofacial Plastic Reconstructive Surgery Vol.23 No.3

The purpose of this study was to find the clinical features of periapical lesions. A total of 130 periapical lesions which were obtained from biopsy and diagnosed histopathologically as periapical cyst, periapical abscess, and periapical granuloma at the Department of Dentistry in Hanyang University Hospital were throughly analysed according to the distribution and incidence of age, sex, location, and so on. The following results were obtained : 1.Out of 130 periapical lesions, 88 cases(67.7%) were periapical cysts, 30 cases(23.1%) were periapical abscesses, and 12 cases(9.2%) were periapical granulomas. 2.The periapical lesions occurred most frequently in the third decade, and followed by the fourth, fifth, sixth, and second decade. The periapical cysts occurred most frequently in the third decade(26.1%), the periapical granulomas in the fourth decade(33.3% ) the periapical abscesses in the sixth decade(26.7%). 3.The periapical lesions were more frequent in men than in women with the ratio of men to women of 1.4 : 1. The radio of men to women of periapical cysts was 1.6 : 1, that of periapical granulomas was 0.5 : 1, and that of periapical abscesses was 1.3 : 1. 4.The periapical lesions were more frequent in maxilla than in mandible with the ratio of 1.2 : 1. The ratio of maxilla to mandible of periapical cysts was 1.5 : 1, that of periapical granulomas was 0.5 : 1, that of periapical abscesses was 1 : 1. 5.The most commonly involved location of the periapical lesions was maxillary anterior teeth(40.8%), and followed by mandibular molars, mandibular premolars, and mandibular anterior teeth and maxillary molars. The most frequent location of the periapical cysts was maxillary anterior teeth(48.9%), that of periapical granulomas was mandibular molars(50.0%), that of periapical abscesses was mandibular molars(40.0%).

중·장거리 선수들의 강력한 스프린트성 반복운동후 혈장 젖산, 젖산탈수소효소 및 젖산탈수소 동위효소의 변화

이규성,김학렬,최용어 韓國體育大學校附屬 體育科學硏究所 1992 韓國體育大學校附屬 體育科學硏究所論文集 Vol.11 No.1

훈련된 중, 장거리 런너를 대상으로 강력한 스프린트성 운동(400m)을 반복적으로 수행하였을때 유발되는 형중 젖산농도, 젖산탈수소효소 및 젖산탈수소 동위효소의 변화를 평가함으로서 무산소성 운동에 대한 LDH 활성도의 특성을 재검토하고 이러한 무산소성 운동을 반복적으로 실시함으로서 유발되는 생체의 스트레스 및 근섬유 동원양상을 평가하고자 400m 트랙을 이용하여 강력한 스프린트 운동을 10회 동안 반복적으로 수행 하였다. 혈중 젖산농도, 젖산탈수소효소 및 젖산탈수소 동위효소를 분석하기 위한 혈액샘플은 400m 질주후 5분의 유식을 취하는 중 3분 경과시에 약 5ml의 혈액을 채혈 하였으며 혈액쌤플의 일부는 혈중 젖산농도를 분석하기 위하여 0.3M Perchloric acid 1000ul에 전혈 200ul를 첨가하고 30초간 진탕한후 원심분리하여 제단백 하였으며 상충액을 냉동보관하였다. 상충액은 1120ul Regent를 혼합하고 실온에서 60분간 방치한후 파장 340nm에서 time scan법으로 측정 하였다. 남은 혈액샘플은 혈장을 분하 하였으면 Beckmann Paragon 법을 이용하여 tltal LDH 활성도를 측정 하였다. 또한 LDH isozyme은 전기영동법으로서 Agarose gel을 사용하여 5개의 동위효소를 분리야였으며 scanning densitometer를 이용하여 상대적 %를 산출하였다. 스프린트성 반복운동에 따른 혈중 젖산농도는 안정시에 비해 1회 400m 질주 후 크게 증가된 수준(p<0.00001)을 나타내었으나 10회 질주가 반복될때가지 더이상의 유의한 증가 없이 전체적으로 일정한 수준을 유지 하였다. 그러나 total LDH 활성도는 혈중 전산농도와는 달리 안정시에 비해 400m 반복힛수에 따라 점차적으로 증가되는 경향을 나타내었으며 9회 400m 반복질주까지 안정시 수준과는 유의한차가 없었으나 10회 400m 질주후 증가수준은 안정시 수준보다 유의하게 높은 수준(p<0.01)을 나타내었다. 또한 total LDH 활성도의 상대적 %로 나나탠 LDH isozyme은 H-type(LDH1+2)의 경우 안정시에 비해 400m의 반복운동에 따라 감소되는 경향을 나타내였으며, 특히 LDH2에서 반복질주간에 통계적 유의차(p<0.01)를 나타내었다. 반면에 M-type(LDH3+4+5)은 반복 운동의 빈도에 따라 점차적으로 증가되는 경향을 나타내었으며, 특히 LDH4와 LDH5에서 현저하게 큰 증가경향을 나타내었다(p<0.001). 이러한 변화양상에 따라 M/H Subunit ratio가 점차적으로감소되는 경향을 나타내었으나 유의한차(p>0.05)는 없는 것으로 나나났다. 결과적으로 본 연구에서의 400m 반복적 질주에 따른 혈중젖산, total LDH 활성도 및 M-type LDH isozyme은 크게 증가를 나타내었다. 이러한 연구결과가 시사하는 바는 400m 반복적 질주에 따른 높은 혈중젖산의 축적이 증가된 totlal LDH 활성도와 M-LDH isozyme분포와 밀접한 관련성을 나나탠다는 것을 시사하는 바이다. The Purpose of this study was to-examine the profile of Lactate dehydrogenase activity during exercise by evaluating a changes of blood lactate concentration, LDH and LDH isozymes induced as a strenuously performed repetitive exercise(400m). Also, it was estimated from a physiological stress and recruitment patterns of muscle fibers indueced as an anaerobi exercise performed. Ten elite middle and long distance runers were employed for this study. Exercise protocol utilized a 10th 400m sprint run. Blood sample for analyzing the blood lactate concetration, lactate dehydrogenase, lactate dehydrogenase isozymes was collected at 3min out of rest period of 5min after 400m maximal run. One portion of the blood sample for analyzing a lactate concentration was deprotenized from 0.3M perchlioric regent to analyze a blood lactate cocnetration was measured by time scan methods in 340nm wave length after 60min ambient temperature. The reminder of the blood sample was stored in refrigerator after centrifuge. Total LDH activity of plasma was examined by using Beckman Paragon tchniques. Also, LDH isozymes was determined to electrophoresis separation by using agarose gel buffered by paragon LD isoenzymes kit. These distribution of LDH isozymes was calculated from a relative percentage by scanning densitometer. Blood lactate concentration followed strenuous repetitive exercise(400m) was shown significantly increased levels (p<0.0001) from 1th to 10th 400m maximal run in comparison with levels of rest. However, it was sustained a const.ant levels without more significant increase from 1th maximal run to 10th run. Total LDH activity showed a progressivly shift, trend as 400m run went on repetitively but, there was not significant difference(p>0.05) from rest levels to 9th maximal run. However, total LDH activity after the 10th 400m maximal run showed significantly increased levels(p <0.01), compared with rest levels. Also, distribution of LDH isozymes determine as relative percent.age of total LDH activity was displayed a decreased levels in case of H- specific type(LDH1+2) by increasing of 400m repetitive frequency. Especially, there displayed a significant difference(p<O.O1) in the LDH4 between 400m repetitive run. Wheareas, M- specific type(LDH3+4+5) was shown a increased levels by increasing of 400m repetitive frequency. Especially, there was significant difference (p <0.001) in the LDH 4 and LDH5. H/M subunit ratio followed changes of LDH isozymes distribution was shown a decreased levels, but there was not significant difference(p >0.05). In Conclusion, The results of this study showed a increase in blood lactate concentration, total LDH activity and M -type LDH isozymes. It was suggested that increase levels of blood lactate accumulation followed 400m repetitive maximal run was a close relation with the increase levels of total LDH activity, and M-LDH isozymes distribution.

점증부하와 지속부하 운동강도가 회복기 생리적 변화에 미치는 영향

김학렬,노성규,손태열,우도영 龍仁大學校 體育科學硏究所 1991 體育科學硏究論叢 Vol.1 No.1

1. The time of break point between Fast-component and slow component of O₂ up-take curve was presented at 12sec after recovery and its level of % VO₂max showed 32.18% VO₂max(Incremental) and 32.98% VO₂max(Continuous). 2. There were no significant differences of the break point between Incremental load and continuous load during recovery time. By above results, Though it was suggested that there will no problem for select any kind load exercise to evaluate O₂Debt during recovery time, but it shall be more desirable that Incremental load be applied to aged or women subjects and continuous load be applied to athletes or healthy subjects. To examine the level of % VO₂max which points the break point between Fast component and slow component by analyzing V E, VO₂, and LA concentration during recovery period after two kinds of treadmill exercise, 10healthy men(32.3%±4.72yrs) were tested as subjects. The methods of exercise load were Incremental load(start with 1.5mph, increasing the speed of 1.1mph at every 2min) and continuous load(continual running with the speed of 100% VO₂max level) with fixed 6% grade of treadmill. Results from the two kinds of load exercise are follows ;

조선대학교 의과대학 의학과 학사편입학제도의 전향적 검토

임성철,박상기,도남용,박상학,이승일,송창훈,박종 조선의대 1998 The Medical Journal of Chosun University Vol.23 No.1

Antioxidant and cytoprotective effects of enzyme‐extracted constituents of Protaetia brevitarsis seulensis powder

Choi In‐Hag,Choi Sung‐Up,Son Jin‐Sung,Jang Woo‐Whan,Chung Tae‐Ho 한국곤충학회 2021 Entomological Research Vol.51 No.2

This study was aimed to compare the antioxidant and cytoprotective effects of hot‐water and enzyme‐extracted constituents of Protaetia brevitarsis seulensis powder. The products of enzymatic extraction had 1,1‐diphenyl‐2‐picrylhydrazyl (DPPH)‐radical‐scavenging activity, cytotoxic effects, and provided cytoprotection against H2O2 and intracellular reactive oxygen species. Enzymatic extraction improved DPPH‐radical‐scavenging activity relative to hot‐water extraction (P < 0.05), with inhibition rates of 33% at 500 μg/mL and 35% at 1000 μg/mL. Cell viability ranged from 100 to 122%, and was higher for hot‐water than for enzymatic extraction (P > 0.05). Hot‐water extraction achieved greater cytoprotection against H2O2 than enzymatic extraction. However, enzymatic extraction achieved greater antioxidant and cytoprotective activity against reactive oxygen species than hot‐water extraction. These results provide evidence of the antioxidant and cytoprotective effects produced by enzymatic extraction of the active ingredients from Protaetia brevitarsis seulensis powder.

남성 성기자해

김상훈,문남식,황걸,박상학,김학렬,김경환 朝鮮大學校 附設 醫學硏究所 2005 The Medical Journal of Chosun University Vol.30 No.2

Background and Objectives: Intentional self-mutilation of the genitals in male is exceedingly rare. As the authors experienced 3 cases of male genital self-mutilation while psychotic, we investigated with psychiatric points of view including general and psychiatric characteristics of genital self-mutilation in Korea. Materials and Methods: Total 21 cases of the genital injury were obtained from the index book of Journal of Korean Neuropsychiatric Association and the Electronic Library Search Engine. From these, excluding the 4 accident-caused cases of penile amputation, the authors investigated 17 cases in terms of general epidemiological characteristics, the type of mutilation, diagnostic classification, psychodynamics of their behavior. Results: Epidemiological data showed that the most of the genital self-mutilation cases are twenties (52.9%); most are single (64.7%). In terms of the mutilation types, complete transection of penis type were committed most frequently (72.1%). The formal diagnoses were mainly schizophrenia (82.3%) and schizoid personality disorder(11.8%). Psychodynamically, lots of cases could be explained as to punish failures in the male role (20.6%), related to religiosity (14.7%), and related to physical pain or somatic illness (14.7%). Conclusion: We are unable to say exactly what prompts a man to divest himself of his genitals. On the basis of 17 cases, we are willing to hazard several risk factors. For individuals psychotic at the time of act there seem to be at least three paradigmatic at-risk groups: (1) younger acutely psychotic men with related to cure or punish failures in the male role, (2) the men with personality disorders who act rageful feelings against themselves and/or close objects, and (3) sociocultural factors known to contribute to such an act include some complex religious belief regarding purification or resisting temptation. Psychological factors yet undetermined may be' equally important.

의과 대학생의 심리적 특성과 학업 성취도와의 관계

박상학,박찬원,조용래 大韓神經精神醫學會 1999 신경정신의학 Vol.38 No.5

연구목적 : 의과대학생들의 심리적 특성을 조사하여 이러한 특성과 학업 성취도와의 관계를 알아보고, 더 나아가 그들의 학업 성취도를 예견할 수 있는 요인을 탐색해보고자 하였다. 방 법 : 의과대학 의학과 1, 2, 3학년에 재학중인 학생 489명을 대상으로, 이전 유급 횟수, 여러 가지 심리적 특성들을 자기 보고형 설문지로 조사하였고, 이를 학기말 성적과 비교, 의과 대학생의 심리적 특성과 학업 성취도의 관계를 조사하였다. 결 과 : 1) 유급 경험자는 34.3%, 편입 경험자는 6.7%였다. 유급 경험 횟수는 1회부터 6회까지였다. 2) 이전 유급 경험은, 성적(G.P.A), 수행 불안, 자기 효능감과 각각 유의한 부적 상관을 나타낸 반면에, 시험 불안과는 유의한 정적 상관을 나타냈다. 이전 유급 경험은, 우울, 자기 불일치, 상태 불안등과 유의한 상관을 보이지 않았다. 3) 학업 성취도는 성별 및 자기 효능감 양자 모두와 각각 유의한 정적 상관을 나타낸 데 비해, 우울, 자기 불일치, 시험 불안, 상태 불안등과는 유의한 부적인 상관을 보였다. 4) 나이, 성, 편입경험, 유급, 우울, 자기불일치, 시험 불안, 상태 불안, 수행불안, 자기 효능감 등은 학업 성취도의 10.86%를 설명하였다. Objective : Several psychological characteristics of medical students were investigated, the relationship between these characteristics and academic achievement was identified, and futhermore some significant predictors of their academic achievement were explored. Method : Subjects were a total of 489 medical students, 1st, 2nd, 3rd year in Chosun university as of in 1998. We administered self-report questionnaires including age, sex, grade failure, and transfer experience. And Beck Depression Inventory, Achievement Self-Discrepancy Scale, Self-Efficacy Scale, State-Trait Anxiety Inventory(state), Test Anxiety Scale, and the Inventory of Performance Anxiety were handed out to them on April 1998. After the semester, we examined the academic achievement according to grade point average. Person's correlations were calculated to explore the relationships between grade failure and other psychological variables, as well as the relationships between academic achievement and other psychological variables. The amount that academic achievement was explained by the psychological variables was obtained using multiple regression analysis. Result : 1) In 489 students, grade failure was 168(34.3%), non-failure was 321(65.7%), and transfer was 33(6.7%). 2) While G.P.A., performance anxiety, and self-efficacy, respectively, were negatively correlated with the failure, test anxiety was positively correlated with the grade failure. There were no statistically significant correlations between grade failure and depression, self-discrepancy, or state anxiety. 3) Academic achievement was positively correlated with both gender and self-efficacy, whereas it was negatively correlated with depression, self-discrepancy, test anxiety, and state anxiety, respectively. Female students were better than males in academic achievement. 4) The amount that age, gender, grade failure, transfer, depression, self-discrepancy, test anxiety, state anxiety, performance anxiety, and self-efficacy accounted for academic achievement was 10.86% totally. Conclusion : Gender, grade failure, and depression in medical students affected their academic achievement significantly.