갑상선 초음파검진의 유용성

배오근,김재권,강명순,조영익,김임봉,신유진,임성규,서민호 한국건강관리협회 2000 건협 Report Vol.3 No.-

흉통의 양상에 따라 분류한 불안정형 협심증 환자의 임상적 소견의 비교

김명수,김성구,정호석,온영근,신원용,김철현,최태명,현민수,권영주 순천향의학연구소 2001 Journal of Soonchunhyang Medical Science Vol.7 No.1

Background and aims : The clinical syndrome unstable angina pectoris that encompasses a variety of symptoms and clincal presentations of transient episode of myocardial ischemia, was devided to several subgroups. Also, it has variable pathophysiologic factors to cause myocardial ischemia. According to clincal presentation, coronary angiographic finding and prognostic factor, the result of unstable angina pectoris is variable. In fact, there were a few data reported on the prognosis of wide spectrum of patients with unstable angina. However, the precise risk of subgroups according to classitication has not been established because it was difficult to compare between studies. We classified unstable angina pectoris by clinical nature of chest pain, and performed to establish and compare the clinical presentations, coronary angiographic findings, treatement and prognosis of patients with unstable angina within subgroups of classification. Methods : Retrospenctive data for 164 unstable angina pectoris patients admitted to the Internal Cardiology Division of Soon Chun Hyang University Hospital from May 1996 to July 1999 was analyzed. The patients were classified into one of the following categories: Class I, new onset of severe angina; Class II, acceleration of previous chronic stable angina; Class III, angina at rest. Clinical presentations, echocardiographic findings, coronary angiographic findings, treatment and prognosis were compared. Results : From the total 164 patients, the subjects of classes were as follows : Class I, 46 cases (28.1%); Class II, 74 cases (45.1%); Class III, 44 cases (26.8%). In view of age distribution, the 7th decade had the highest incidence, and then, 6th, 8th decades were followed. There was no baseline differences among the 3 classes with respect to gender, number of risk factors. Significantly, class II showed more severe findings in abnormal Q wave 15 cases (20.8%), total occclusive lesion 10 cases (20.8%) and three vessel coronary disease 11 cases (22.9%) than other classes. The change of ST segment was significantly apparent (p<0.02) among class I 28 cases (60.8%), class III 26 cases (59.0%), comparing with class II 30 cases (40.5%). Class III had the higher incidence of one vessel coronary artery disease than class I and III. The heparin treatment was performed in 99 cases (60.1%). The incidence of nonfatal myocardial infarction was much more in class I and III, each 4 cases (8.7%, 9.8%) than in class II 1 cases (1.4%). In-Hospital death was occurred in class I and II, each 1 case. Conclusion : The patients with the acclerated angina from chronic stable angina had more severe coronary artery disease than other classes, but they had better in-hospital prognosis.

六味知黃湯 投與가 高壓環境에 露出된 흰쥐의 血液造成과 臟器造織에 미치는 影響

오재근,강명신,조준용,이영일,최용어 韓國體育大學校附屬 體育科學硏究所 1996 韓國體育大學校附屬 體育科學硏究所論文集 Vol.15 No.1

This study was purposed to investigate the effect of yukmijihwangtang on rat blood components and organ histopathologic changes in the different environments of hyperbaric ambient air. The pharmacological effects of yukmijiwhangtang in oriental medicine have been reported to improve general condition and treat mental and physical weakness due to overload. 84 Male Sparague-Dawely rats, 200-250 g weight, were housed two per cage, fed Standard Rodent Diet with water ad libitum. The animals were assigned to 3 main groups for the blood components and gas analysis : normobaric control group (NC ; N=4), hyperbaric control group (HC ; N=8), hyperbaric medication group (HM ; N=8). HC and HM group were devided into 2 subgroups and kept on different situation of the hyperbaric ambient air (2ATA or 3ATA) for 2 hrs. HM group was administered 10cc extract of boiled yukmijiwhangtang before exposure. For histopathological analysis, hyperbaric groups(HC and HM : N=80) was further devided into 2 subgroups according to atmosphere absolute and exposure period : 2ATA (acute, 1, 2, 3, 4 wks), 3ATA (acute, 1, 2, 3, 4 wks). There were 20 groups in total, with 4 animals in each group. Experimental rats of HM group were administered 10cc extract of boiled yukmijiwhangtang 2 times per day and kept on situation of the hyperbaric ambient air (2ATA and 3ATA) 2 hrs per day for four weeks. In order to record the possible effects of yukmijiwhangtang in hyperbaric condition on the blood components, the rats were killed by decapitation directly after the hyperbaric exposure for 2 hrs. But the administered rats were killed on the morning following the last hyperbaric exposure during 4 wks. The samples were taken 2 hrs, 1, 2, 3, 4 wks after the begining of this study. Blood was collected from posterior abdominal vena cava immediately after decapitation. Organs for histopathological assays in hyperbaric groups (HC and HM) were also removed 2 hrs, 1, 2, 3, 4 wks and fixed at 10% formalin solution. The whole blood of 1㎖ was used for the analysis of pH, PO₂, PCO₂, HCO₃, BE, O₂CT, O₂SAT level by Blood Gas Autoanalyzer (Coning 175, U.S.A). And The rest whole blood of 1㎖ was utilized for the measurement of WBC (white blood cell), RBC (red blood cell), Hb (hemoglobin), Hct (hematocrit), MCV (mean corpuscular volume), MCH (mean corpuscular hemoglobin) level by Microcell Counter (Model; CC-170-TDA Co., Japan). Hematological and blood gas analysis and organ histopathological changes after exposure to hyperbaric ambient air were as follow; (1) Hematological parameters were lower in the hyperbaric medication group than all the control groups without WBC, MCV (2ATA) and MCV, MCH (3ATA). But a statistical significance among the groups was not shown. (2) The hyperbaric medication group was lower than another control groups on all parameters of blood gas analysis after 2 hours exposure to hyperbaric ambient air (2ATA and 3ATA) without O₂SAT. But a statistical significance among the groups was not shown. (3) On observing the histopathological system of the lung with microscope, the congestion, edema and hemorrhage on the alveolar sacs and alveolar wall damage in the hyperbaric control group were heavier than in the hyperbaric medication group.

요관 및 방광의 무형성이 동반된 신무발육증 1예

김동출,신은택,이동명,이윤경,기근홍 조선대학교 부설 의학연구소 1998 The Medical Journal of Chosun University Vol.23 No.2

Bilateral renal agenesis is an uniformly lethal malformation occurring in 1-2/10000 birth. This condition is associated with severe oligo-hydroamnios, intrauterine growth retardation, pulmonary hypoplasia and extrarenal anomalies. We experience a case of bilateral renal agenesis associated with agenesis of both ureters and bladder, and single umbilical artery. But the infant had normal pulmonary development. Specific IgM for herpes virus in maternal serum was detected.

양수 다발성 수지 재접합수의 치험례 : 4 cases report

차진한,박명철,김우경,한근태,김수신,백세민 大韓成形外科學會 1990 Archives of Plastic Surgery Vol.17 No.2

Since the first successful replantation operation, several reports have been recorded replantated finger survival with high success rates. But ten and nine digits amputations are not common. It is even more unusual to have all digits suitable for replantation. 4 cases are presented where replantation of ten and nine digits were done at the department of PRS. Guro Hospital, Korea University from March 1987 to Jun 1988. In these cases, the patients were young and healthy, all of ten and nine digits were sharply amputed near the proximal phalanx, so a replantation team of 8 surgeons in alternating fashion replanted all ten and nine digits over 30 hours and each patient received 28 pints of whole blood during the procedure. Under general anesthesia, replantatin of both started simultaneously. All digits survived completely except partial necosis of right little finger in case 1. The ischemic time of each digit ranged from 4 hours and 45 minutes to 31 hours as shown in table 5. The long ischemic time did not criticaly affected the survival of amputated digit. Follow-up was from 12 months to 20 months postoperatively. The functional evaluation revealed as follows: 1. The grasping power ranged 13 lb to 65 lb(average;39.7lb) 2. The pinching power with index finger ranged 5 lb to 15 lb(average:10.2 lb) 3. The palm to pulp distance ranged 0 cm to 6 cm.(average;2.2cm) 4. The two point discrimination ranged 2.5mm to 22mm.(average;7.8mm) 5. The shape of digits were acceptable aesthetically. 6. All 4 patients were able to use both hands well in all activities of daily living.

6주간의 淸暑益氣湯 經口投與가 에너지대사 및 호르몬 변화에 미치는 영향

최용어,강명신,유종만,이규성,오재근,조준용 韓國體育大學校附屬 體育科學硏究所 1994 韓國體育大學校附屬 體育科學硏究所論文集 Vol.13 No.1

The purpose of this study was to investigate the effects of chung-seo-ik-gi -tang administration on the metabolic responses and hormones in 18 healthy-male elite boxes. All subjects were divided randomly with two groups, Chung-sea-ik-gi-tang Group(N=18) and placebo group(N=18) and perfored with 70% of HR max using bycicle ergometer unfil exhaustion. During the submaximal exercise, heart rate was maesured every two min. The blood samples were collected from antecubital vein by 10ml syranges(6ml/each) before immediately after exhaustion, recover-10 min, recover-20 min and recover-30 min. The samples were to analyzed for the level of glucose, lactate, TG, TC, HDL-C, insulin and catecholamine. The results of various blood parameters were summarized as follow; l. Energy substrates (plasma glucose, TG, TC, HDL-C) changes in group C were significantly different from group P. Plasma glucose in group C was significantly lowered at recover-10 min compared to group P (P<0.05). and also TG, TC and HDL-C in group C were significantly increased after 3 weeks compared to group P (P<0.05) whereas. Lactate accumulation in group C was significantly decreased after 3 weeks compared to group P (P<0.05). 2. Plasma insulin level was not showed significant difference between two groups. But insulin depression tendency after 3, 6 weeks in group C was allevated compared to group P. Increasing rate of norepinephrine in group C at Post-exhaustion after 3weeks lowered compared to group P. Norepinephrine in group C at rest periods after 3 weeks showed significant difference compared to group C. The results indicated that Chung-seo-ik-gi-tang had the effects of ergogenic aids on fatigue resistance and recovery from exhaustive exercise at the level of 70% HR max.

소아에서 출혈을 동반한 단일 연소성 용종의 내시경적 절제술

김준기,조상욱,신성하,고영춘,최정영,서강석,강명원,임연근,여향순,김경수 全南大醫大 2001 전남의대학술지 Vol.37 No.3

식도를 포함한 전위장관을 침범한 전이성 악성 흑색종 1예

최정영,김준기,신성하,고영춘,조상욱,서강석,강명원,임연근,여향순,김경수 全南大醫大 2001 전남의대학술지 Vol.37 No.1

운동전·후 淸暑益氣湯 투여방법이 2,000m 달리기시 선수들의 운동피로회복에 미치는 영향

유종만,이규성,강명신,오재근,최용어 韓國體育大學校附屬 體育科學硏究所 1994 韓國體育大學校附屬 體育科學硏究所論文集 Vol.13 No.1

The purpose of this study was to investigate the effects of two different chung-seo-ik-gi-tang administration types on fatigue induced during 2,000 m running in 12 healthy-male elite boxer. All subjects were divided randomly with two groups, Pre-administration Group(A: N=7) and Pre- and Post-administration Group(B: N=7) and performed 2,000 m maximal running. The blood samples were collected from antecubital vein by 10ml syranges(6ml/each) at before exercise, immediately after exhaustion, recover-10 min, recover-20 min and recover-30 min. These samples were used to analyze for the level of glucose, lactate, TG, LDH, pH, HCO₃?, Na??, K??. The statistically analyzed results of various blood parameters were summarized as follow, 1. Plasma glucose were not showed significant difference between two groups. but glucose lwvel at post-exercise and rest-30 min in B group wes significantly decreased. 2. Lactate accumulation in B group was significantly decreased at post-exercise and rest-30 min.. And lactate level at rest-30 min. was showed significant difference between two gruops. 3. Serum LDH response to 2,000 m running at post-exercise and recovary periods was showed significant changes in B group. 4. Venous pH at post-exercise, HCO₃? at post-exercise and rest-30 min. in A group and pH at post-exercise and rest-10, 20 min., HCO₃? at post-exercise were showed significant changes. But there were not showed significant difference between two groups. 5. K?? level in B group was showed significant difference compared to A group. And also K?? level at rest-30 min. in B group was showed significant change. The results indicated that Chung-seo-ik-pi-tang had the effects of ergogenic aids on fatigue and recovery during 2,000 m maximal running.

흰쥐에서 염화비닐 폭로수준에 따른 소변내 thiodiglycolic acid 농도의 변화

왕승준,차봉석,노재훈,신동천,김명수,전근재 大韓産業醫學會 1999 대한직업환경의학회지 Vol.11 No.4

Objectives : It is the objective of this research to identify the variation of thiodiglycolic acid(TdGA) in urine with vinyl chloride monamer(VCM) exposure levels through methylation. Methods : After rats were exposed to vinyl chloride monomer of 4 levels, 0㎎/㎥, 50㎎/㎥, 150㎎/㎥, 500㎎/㎥, respectively, of which urine was sampled in each sampling time of 0 hour, 2 hours, 4 hours, 8 hours, 16 hours, 36 hours, 48 hours. After urine had been methylated with diazomethane in the preliminary experiment and the peak of 146 m/z had been verified, the main experiment was done. Results : In the variation of TdGA with sampling times, concentration of TdGA increased rapidly in 4 hours and then decreased after 8 hours. When the variation of urinary TdGA concentration in urine according to exposure level of VGM was verified through Kruskal-Wallis statistical method at each sampling time, the significant increment with the exposure levels at 2 hours, 4 hours, 8 hours after exposure was clarified. Conclusion : TdGA concentration in urine with increment of VCM exposure level increased, especially significantly at 2 hours, 4 hours, 8 hours of sampling time.