급성 심근경색증에 동반된 승모판 폐쇄부전증의 임상적 특징

정상만,조영일,조화상,유광하,송기호,인행환 건국대학교 의과학연구소 1997 건국의과학학술지 Vol.- No.7

급성 심근경색증에 동반된 승모판 폐쇄부전증의 임상적 특징

정상만,조영일,조화상,유광하,송기호,인행환 건국대학교 의과학연구소 1997 건국의과학학술지 Vol.7 No.-

The early detection and proper management of mitral regurgitation(MR) associated with acute myocardial infarction(MI) is very important to improve the clinical course and outcome of disease. The change of left ventricular shape and regional function, papillary muscle rupture are major determinant of the existence and severity of MR. We performed 2D and M mode echocardiography of 28 patients at the early stage of acute MI to evaluate the existance and degree of MR and its pathogenetic factor. Significant MR occured in 12 (42.9%) patients. In the group of MI with MR, the inferior MI was frequent (7 case) than anterior MI (5 case) comparing to the patient group of MI without MR (inferior MI : 6 case, anterior MI : 10 case) (p<0.01).The left ventricular end diastolic dimension(LVEDD), end systolic dimension (LVESD) and left atrial dimension (LAD) were significantly increased in MI with MR than MI without MR (LVEDD : 57.3 ±8.6 vs 46.4 ±9.2, p<0.05 ; LVESD : 52.9 ±9.2 vs 38.3 ±7.4, p<0.01 ; LAD : 45.4 ±3.8 vs 37.7 ±3.7, p<0.05).However, the ejection fraction was not different between two group two groups. These datas showed that MR was more frequent in inferior MI and the hemodynamic derangement was more serious in acute MI with MR.

全北 401號의 操縱性能에 關한 硏究

鄭興基,徐萬錫 군산대학교 1986 群山水産專門大學 硏究報告 Vol.20 No.3

The Z-test was carried out in order to know the maneuverabilities of the M.S. Jeonbuk 401(303 ton) which is the training vessel of Kunsan National Fisheries Junior College. The main results obtained are as follows: 1. The maneuvering indices K' and T' are 1,132, 0.904, 1,277 and 1,431, 0.959, 1,752 at 10˚, 20˚, 30˚ tests respectively. This results mean that the maneuverabilities are good at the rudder angle 30˚, and the obeying ability is also good at the rudder angle 20˚c. 2. Since the maneuvering indices K' and T' at 10˚ test are just a little high compared with those of other fishing boats, the turning ability of this vessel is considered to be good state, but the boeying ability is considered to be bad state. 3. The running distance at 10˚ test is about 9.5 times of her own length, and doesn't exceed the standard maneuvering distance 5 to 11 times. Therefore, it can be said that the maneuverabilities of this vessel are comparatively good. 4. The relationship between K' and T' is appeared as (1/K') = 0.430+0.648(1/T').

관절염 환자의 실태와 관련요인에 대한 분석적 연구

정승기,남철현,신두만,양숙희,김기열,이미경,문기내 대한보건협회 2002 대한보건연구 Vol.28 No.3

This study was conducted to examine the condition of patients with arthritis and its related factors. Data were collected from 100 people who suffered from arthritis in Seoul. Busan, Daegu, Daejun, Junjoo, and pohang from April 2, 2000 to July 31, 2000. The results of this study are summarized as follows : 1. 6L0% of the subjects were female. The incidence rate of arthritis was higher in the higher age group, lower educated group, and thinner group. In case of male, the incidence rate was higher in the groups of single, residents in big cities, and technicians. In case of female, it was higher in the groups of the married, residents in towns or villages, and housewives. 2. According to the parts of arthritis, knee joint covered 67.4% and backspine joint covered 9.0%. The incidence rate of arthritis was higher in the groups of forties, housewives, single, irreligious people, residents in towns and villages, primary school graduates, thin people, and walk exercisers. 3. The arthritis patients felt pain most when they stood up (31.5%). According to the time when they felt pain most, the time when they were active during daytime was 31.5% and nighttime was 29.8%. When they got up in the morning was 22.4%, while 10.9% felt pain all cay long. 4. they had arthralgia knees and cramp in crook of the knees (21.8%). Their knees ticked when they moved (21.1%). The had to rest hands on anyplace when they stood up (18.7%) and they could not completely unfold their knees. 5. The medical institutions which diagnosed them showed significant difference in the variables of sex, age, marital status, religion, place in residence, education level, economic status, obesity level, exercise, parts of arthritis, and posture of feeling pain. from above results, it can be concluded that it is necessary to develop appropriate medical treatment on the basis of the respondents' socio-democraphic characteristics, pain parts, period of having a pain, satisfaction level with treatment and its related factors. Therefore, related professionals and organizations must develop education program for prevention of arthritis in order to educate them.

Rhizopus japonicus IAM 6029의 Glucoamylase에 관한 硏究 第1報 Glucoamylase의 精製와 性質

鄭萬在,金基淵,李明烈 충북대학교 농업과학기술연구소 1988 農業科學硏究 Vol.6 No.1

These experiments were conducted to investigate the purification and the properties of glucoamylase produced by Rhizopus japonicus IAM 6029. The results obtained were as follows : 1.The optimum culture time, the optimum culture temperature and the optimum amount of added water in the wheat bran medium were about 3 to 5 days, about 30℃ and about 100%, respectively. 2.The crude enzyme was purified by ammonium sulfate fractionation and CM-cellulose columm chromatography. The specific activity of glucoamylase was 220. 2U/mgㆍprotein and the yield was 9.1%. 3.The purified enzyme showed a single band on polyacrylamide disc gel electrophoresis. 4.The optimum temperature, optimum pH, the stable pH range and the stable temperature of the glucoamylase were about 50℃, about pH 4.0, pH 4.0~8.0 and below 40℃, respectively, and it was rapidly inactivated above 55℃.

치료적 공동사회의 한 변형 : It's One Year Follow-Up 1년간의 추적

이만홍,정영기 大韓神經精神醫學會 1983 신경정신의학 Vol.22 No.3

The authors presented a an illustration of the modified therapeutic community, which was organized in Aug. 1981, as a psychiatric inpatient unit of Wonju Christian Hospital, Yonsei University, and was located in one of the strongly culture-bound district in Korea (Kangwon-Do, Wonju). It was an active therapy unit as well as a teaching facility for medical students and nursing students, and was a mixed milieu consisted of 22 to 26 inpatients with heterogenous diagnostic entities. Organization and vicissitude of the therapeutic community was presented in terms of therapeutic team, therapeutic strategies, patient previlige system, and ward activities including community meeting, intensive group psychotherapy family accompanied admission programme, ward round, occupational programme, staff sensitivity meeting etc. Based on the one-year follow-up experience compared with western ones, the authors' discussion was focused on the predicted modification how the concepts and strategies of therapeutic community could be applied and changed in accordance with the socio-cultural characteristics of our country, and several problems were suggested to be examined further as follows; (1) the patient's heterogeneity seemed to be rather contributory to increasing therapeutic effect in the mixed milieu, but where, organic brain syndrome, compensation neurosis and antisocial personality disorder seemed to be contraindicated. (2) the patient priviliege system was successfully applicable to our therapeutic community as an organized democracy and several patient's requirement tasks were developed spontaneously and informally in each step of priviliege system. (3) the patient value system and culture of therapeutic community should be scrutinized in accordance with our socio-cultural background. The mostly frequently confronting and conflict-provoking issues of our therapeutic community were patient's difficulty in expression of aggression, unresolving strong ambivalence toward the authority figure, and the need for new type of leadership for it's resolution. (4) the counter-transference reaction seemed to be final problem to be successfully dealt with in the therapeutic community just as in individual psychotherapy, and that was analyzed in 3 system-levels; counter-transference reaction originated from the therapists' intrapsychic conflict, the one from the interaction between therapists' subgroups, and the one from the therapeutic community organization as a whole.

여성호르몬 대체요법후 체중변화와 베타3 아드레날린 수용체 유전자형의 연관성에 관한 연구

이기호,김상만,이득주,최희정,한인권 대한비만학회 2003 The Korean journal of obesity Vol.12 No.3

연구배경: 폐경 전후에서의 체중 증가와 여성호르몬과의 연관성이 지속적으로 논의되어왔다 교감 신경계는 지방대사를 촉진하여 대사적 열생산을 증가시키는 작용을 가지고 있으므로 이와 관련하여 베타3아드레날린 수용체의 유전자형이 폐경여성에서 여성호르몬 대체요법 이후의 체중증가와 연관이 있는지를 밝히고자 본 연구를 시행하였다. 방법: 1995년부터 2002년 5월까지 삼성제일병윈 비만클리닉 및 갱년기 클리닉에 방문하여 여성 호르몬 대체요법을 시행 받았으며, 폐경에 관련한 과거력, 여성 호르몬 투여 전후의 체중, 체질량 지수에 대한 자료를 확보할 수 있곤, 베타3 아드레날린 수용체 유전자의 다형성을 분석한 92명을 최종 연구 대상자로 하였다. 결과: 베타3 아드레날린 수용체 유전자 다형성 분포는 Trp64Trp형 39.1%, Trp64Arg형 25.0%,Arg64Arg형 34.8%,로 나타났다 여성호르몬 투여 전 체중의 평균은 61.07±7.06이었으며, 여성 호르몬대체요법 후 체중 변화의 평균은 1.28±3.20 증가로 나타났으나, 통계적으로 유의하지 않았다 β3 아드레날린 수용체 유전자 아형에 따른 체중의 평균 변화는 Trp64Trp형에서 1.86±2.94 증가, Trp64Arg형 0.74±2.97 증가, Arg64Arg형 1,00±3.61 증가로 나타났으나 이들 모두 통계적 유의성은 없었으며, 세 아형간의 변화량도 유의하지 않았다. 결론: 폐경여성에서 여성호르몬 대체요법 후 체중이 증가하였으나 통계적으로 유의하지 않았으며, β3아드레날린 수용체 유전자 아형에 따른 차이를 관찰할 수 없었다. Background: The study results to determine the relationship between postmenopausal estrogen use and weight gain have not been consistent. Genetic studies have reported the association of BMI with the beta3-adrenergic receptor gene polymorhism. This study as designed to indentify association of beta3-adrenergic receptor gene polymorhism with weight gain related to HRT in postmenopausal women. Methods: 192 postmenopausal women at a general hospital, Bariatric and climacteric clinic have been collected. Subtypes of beta3 adrenergic receptors were measured and physical, anthropomeric data including body fat and BMI was obtained before and after HRT. Results: Arg/Arg group was 34.8%, Trp/Arg group was 25.0%, Trp/Trp group was 39.1%. Mean weight gain in 192 postmenopausal women was 1.28±3.20 kg and the percent changes in weight gain between initial and final point was 2.32±5.66% but these resulst had no statistical significance (p>0.05). Weight gain(%) were 2.24%(95% C.I 0.35~4.13) in Arg/Arg group, 1.08%(-1.17~3.29) in Trp/Arg group and 3.18%(1.49~4.92) in Trp/Trp, but these results did not show statistical significance(F=1.13, p=0.03). Conclusion: Polymorphism of beta3 adrenergic receptor gene was not associated with weight gain after HRT in postmenopausal women. From these results, we may conclude that polymorhism of beta3 adrenergic receptor may not be the predicting factor to understand the weight gain after HRT in postmenopausal women.

Bi를 첨가한 BaTiO_3 자기반도체

孫炳基,丁潤夏,李萬浩 慶北大學校 1976 論文集 Vol.21 No.-

The (Ba_(1-x)Bi_x) TiO_3 (0.05≤x≤5a/0) has been prepared by sintering the mixture of BaTiO_3 and Bi_2O_3. The measuremnts of the capacitance and resistance showed that the optimum doping level of Bi was 0.1≤x≤0.5a/0. Typically, for the sample of x=0.5a/0, thearea capacitance was 3.5nF/㎠ which gave the effective dielectric constant of 3.4×10^4. The change in capacitance and loss tangent were 0.4∼-26% in the temperature range of -50∼85℃ and 5∼-7% in the temperature range of -50∼150℃ relative to room temperature capacitance and loss tangent, respectively. The frequency characteristics of the capacitance and loss tangent for the sample of 0.5a/0 showed that this sample was suitable for a capacitor in the higher frequency region than 1 kHz. Although the loss tangent(0.1) and the insulation registance (0.02MΩ·μF) are lower than JIS values, the semiconductors in the optimum doping range are valuable to be used as a high dielectric capacitor. The x=0.5a/0 sample had shown a PTC thermistor characteristics by having the resistance anomaly index ψ=2.5 and the room temperature resistivity ρ=10^4Ω·㎝.

大家畜의 受精卵 移植에 關한 硏究

李基萬,鄭吉生,高光斗 건국대학교 1982 學術誌 Vol.26 No.2

This study was carried out in order to induce multiple birth following egg transfer in Korean native cattle, and composed of three experiments ; induction of multiple birth following GTH single administration, Ovarian response to the administration of GTH in combination with Prostaglandin F2α and non-surgical egg transfer following superovulation and non-surgical recovery of fertilized eggs. The results obtained in three experiments were summarized as followings: Experiment I. Induction of multiple birth following GTH single administration. (1) Average duration from PMS administration to the onset of estrus was 3.8 to 4.7 days and no difference due to dosage and administration site of PMS were observed. (2) Duration of induced estrus was ranged from 3.1 to 4.6 days and that of induced estrous cycle was shortened by the length of induced estrus. (3) The most slowed follicles (5.3- 5.5) were observed in the cattle administrated with 2,000 IU of PMS and 1,000 IU of PMS was considered to be the optimum dosage for the limited ovulation. (4) Ovulation rate was declined when the PMS dosage was increased more than, 1000 IU (5) Highest rate of twin birth (35.7%) was obtained from the cattle treated with 1,000 IU of PMS and the next was the catties treated with 500 IU and 2,000 IU of PMS, respectively. Experiment II. Ovarian response to the administration of GTH in combination with Prostaglandin F2α. (1) Average duration from PMS administration to the onset of estrus was 5 days and the duration was shortened with the increasing dosage of PMS. (2) Duration of induced estrus was ranged from 2.3 to 4.5 days and the duration of estrus was shortened with the decreasing dosage of PMS. (3) Number of follicle obtained from the cattle treated with 4,000, 3,000, 2,000, 1,000 and 500 IU of PMS were clarified to be 11.4, 11.5,7,2.3 and 2.5, respectively, after 4.8-5.2 days of PMS administration. (4) Observing the results of slaughter, ovulation rates of the cattle treated with 4,000, 3,000, 2,000, 1,000, and 500 Iu of FMS were 16.3, 35.6, 60.0, 65 and 75%, respectively. (5) The numbers of degenerated, or bled follicle were increased with the increase of PMS dosage. Experiment III. Non-surgical egg transfer following superovulation and non-surgical egg transfer. (1) Average six eggs per donor were ovulated and 65% of them were recovered by non-surgical technique. (2) Eighty two percent of eggs recovered were found to be normal morphologically and were at 4-32 cell stage, respectively. (3) Seventy five percent of cattle treated with prostaglandin F2α were synchronized in their estrus within 4 days of administration. (4) No twin fetation was obtained from the five recipients received fertilized eggs.

부산지역 무균성 뇌막염 원인 바이러스의 분리 및 동정 : 1998년을 중심으로

김영희,정영기,김기순,지영미,윤재득,김병준,구평태,민상기,정구영,김만수,조경순 동의대학교 기초과학연구소 2000 基礎科學硏究論文集 Vol.10 No.1

The incidence of aseptic meningitis infection is ensuing and threatening the health of children. Enteroviruses are the major agents of aseptic meningitis and identification of virus has been a clue to diagnosis and epidemiology. The outbreak of aseptic meningitis occurred in Pusan, 1998. Patients were concentrated from April through November. Children were more susceptible than adults. Among 306 cases of specimens from stool, throat swab tested, only 7.2% were positive on virus isolation, 12 cases from stool and 10 from throat, respectively. All isolated 7 serotypes of viruses represented cytopathic effect on cultured cells. Three types of echovirus 6, 25, 30 and coxsackievirus B2, B3, B4, B6 were identified by neutralizing anti body test. Isolated coxsackievirus and echovirus were observed by an electron microscope with negative staining.