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김용배,장원기,황보영,김화성,안규동,이병국,이용진,이종은,이준숙,이찬구,이한정,이성수 순천향대학교 2006 Journal of Soonchunhyang Medical Science Vol.12 No.1
Objective : Serum uric acid has now been identified as a marker for a number of metabolic and hemodynamic abnormalities. The aim of this study is to evaluate risk factors which influence hyperuricemia in the citizens of Asan. Method : The study design was cross-sectional and research subjects were 1086 citizens of Asan. General characteristics, cigarette smoking, alcohol consumption, and past history were obtained by interview using a structural questionnaire. Also, we measured height, weight and blood pressure, and serum uric acid of the subjects. Results : The mean serum uric acid level was 5.27 ㎎/㎗ in men and 4.01 ㎎/㎗, in women, In the multiple logistic regression analysis, statically significant risk factors of hyperuhcemia were gender, body mass index, blood lead concentration, and serum creatinine. Conclusion : Our results suggest that gender, body mass index, blood lead concentration, and serum creatinine might be the most important risk factors of hyperurcemia. Education program as well as routine check-up for serum uric acid was highly recommended for the effective prevention of hyperuricemia.
이대형,유형은,이종수 배재대학교 자연과학연구소 2004 自然科學論文集 Vol.15 No.1
To develop a new functional fruit wine, quality characteristics and physiological functionality of wild grape wine(WGW) were investigated and compared with that of foreign grape wine(FGW). Ethanol contents of WGW was 11.0%, similar to that of FGW(10.6%), but total acidity(0.67%) and total anthocyanin content(A_(520): 0.32) of WGW were higher than those of FGW(0.4%, 0.22). Antioxydant activity and SOD-like activity of WGW which is related in anti-aging functionality were 93.6% and 53.0%, respectively, higher than those of FGW(85.9%, 42.5%). From this results, we concluded domestic wild grape wine is very excellent functional fruit wine.
이병국,황규윤,장봉기,김용배,리갑수,안현철,김화성,이성수,안규동,박종범 순천향대학교 산업의학연구소 1999 순천향산업의학 Vol.5 No.1
The inhibition of δ-aminolevulinic acid dehydratase (ALAD) in the heme synthetic pathway results in increased protophoryphyrin (ZPP) and δ-aminolevulinic acid (ALA) and is responsible for some of toxicological effects of lead. This enzyme is coded by the ALAD gene containing 2 co-dominant alleles. The polymorphisms of ALAD gene may be related to differential effects of lead on ZPP and ALA, ALAD genotype was measured in 975 Korean male lead workers, of whom 897 were homozygous for ALAD1 (ALAD 1-1 genotype) and 96 were heterozygous for ALAD2 (ALAD 1-2 genotype). Blood lead in subjects with ALAD1 was significantly higher than those with ALAD2 (p = 0.01). No difference between ALAD genotypes was found for age, exposure duration, ZPP, ALA, hemoglobin, hematocrit, body mass index, tobacco and alcohol use. After adjustment for possible confounders, ALA and ZPP became significantly elevated in ALAD1 subjects (p = 0.004 and 0.055, respectively). This result suggests that ALAD1 subjects may be more susceptible to the hematotoxicologic effects of lead than ALAD2 subjects.
동물원에서 사육중인 Japanese Macaque (Macaca fuscata)에서 Zoletil 마취에 관한 연구
이재일,이수진,홍성혁,신남식,김덕환,박창식,전무형,조종민,김영석,김명철 충남대학교 형질전환복제돼지연구센터 2004 논문집 Vol. No.8
To evaluate the effects of Zoletil (tiletamine-zolazepam) that have been widely used for the chemical restraint and anesthesia of primates, on physiologic alteration, blood gas analysis and anesthetic duration in the Japanese macaque(Macaca fuscata), this study was carried out. Zoleril was administered by intramuscular injection, Evaluation of temperature, heart rate, respiration rate and blood gas analysis were performed before administration ancl at 1,10, 20, 30, 40, 50 and 60 min after administration, and induction and maintenance time was recorded. There was no significant difference in heart rate, PCO₂PO₂after Zolcril administration and temperature, respration rate, pH were significant difference compared with those of before administration, The induction time was 2.5±l.Omin and maintenance time was 86±23.2min. It was considered that Zoletil could he usefully used for the sedation and immobilization of Japanese macaque reared in zoological garden.
이종수,김도영 梨花女子大學校 醫科大學 醫科學硏究所 2001 EMJ (Ewha medical journal) Vol.24 No.3
Infectious mononucleosis is an acute lymphoproliferative disease that is most common in children and young adults and is caused by Epstein-Barr virus. Characteristic clinical feastures include : 1) fever, sore throat, and lymphadenopathy ; 2) an associated absolute lymphocytosis greater than 50%, of which at least 10% are atypical lymphocytes in the peripheral blood ; 3) development of transient heterophil and persistent antibody responses against Epstein-Barr virus ; and 4) abnormal liver function tests. The most prevalent age of infectious mononucleosis in Korea was less than 5 years old and it has been very rare in adulthood. However, recently in Korea, possibly due to the increasing number of people who are non-immune to Epstein-Barr virus, the age range seems to be increasing from young childhood to over 10 years old and even to adulthood. We present a 19-year-old man who showed typical clinical features of infectious mononucleosis.
A Hybrid Control Algorithm for the Direct Drive Robotic Manipulators
李鍾洙,崔京三 弘益大學校 1989 弘大論叢 Vol.21 No.2
본 논문에서는 직접 구동 팔의 효율적인 경로 제어를 위해 이산 제어 성분과 연속 제어 성분의 두 가지가 혼합된, 새로운 하이브리드 제어 방식을 제안한다. 이산 제어 성분은 로보트 팔의 근사적 추정 모델을 이용하여, 로보트의 규정경로를 따라 계산하는 규정 토오크로서, 로보트의 동력학 정보를 계산하기 위해 필요한 많은 계산 시간을 고려하여, 큰 표본 시간을 갖도록 한다. 이 제어 입력은 로보트 관절들간에 상호 작용하는 강한 결합 토오크를 근사적으로 보상한다. 연속 제어 성분은 가변 구조 제어 이론을 변형한 제어 입력으로서, 모델링 오차나 작업부하의 변화에 따른 외란 등에 강하게 대처하여 경로 추적의 정학성을 높일 수 있도록 한다. 최근의 제어기 개발 추세에 따라 제안한 알고리즘을 디지탈 제어로서 실현할 경우 '연속 제어 성분은 이산 제어 성분에 비하여 매우 작은 계산량 만을 필요로 하므로, 두 가지의 서로 다른 표본 시간을 갖는 이산 제어 형태로서 구현할 수 있음을 보였다. 제어 시스템의 안정성을 증명하였으며, 제안한 알고리즘의 효용성을 보이기 위하여 작업 부하 오차, 모델링 오차 및 계산에 의한 제어 입력의 시간 지연을 고려하여 3자유도의 직접 구동 로보트 팔에 대하여 시뮬레이션 하였다.