국회의원의 지역구대표기능에 관한 일고찰

윤종빈 한국외국어대학교 사회과학연구소 2001 社會科學論集 Vol.19 No.1

국회 예산심의의 결정요인에 관한 신제도론적 접근

윤종빈 한국외국어대학교 사회과학연구소 2001 社會科學論集 Vol.18 No.2

6·13 지방선거과 시민단체의 역할 분석

윤종빈 명지대학교 사회과학연구소 2003 사회과학논총 Vol.19 No.-

한국인에서 DXS7132 유전좌와 GATA31D10 유전좌의 다형성에 관한 연구

안종성,장영길,이숭덕,신창호,이윤성,이정빈 大韓法醫學會 2000 대한법의학회지 Vol.24 No.1

The validation study for two STR loci on X-chromosome, DXS7132 and GATA31D10, was done including allelic distribution and frequency of each allele to use these results for individual identification and paternity testing. For 496 unrelated Koreans, above two STR loci were amplified simultaneously using duplex PCR amplification method. The amplified products were analyzed by polyarylamide gel electrophoresis followed by silver staining. In male DXS7132 locus revealed 7 different alleles ranging from 276bp to 300bp. The largest allele was consisted of 14 repetition of [TCTA] unit and took 0.3417. The allele 15 followed next as 0.3165 and allele 13 as 0.1726. In female general distribution was same except one allele, allele 18 was found additionally. The heterozygosity was 0.7706 and 23 different genotypes were found. Polymorphism information content(PIC) was 0.727. Two cases of mutation were noted in DXS7132 locus In both male and femal 7 different alleles were noted in GATA31D10 locus and the alleles ranged from 195bp to 231bp. The allele 15(199bp) took the majority of all as 0.825. The other alleles showed rather relatively low frequency. The heterozygosity was 0.2385 and 11 different genotypes were found. PIC was 0.2521, and no mutation was noted in GATA31D10 locus. Considering these two loci together, 22 different halpotype were noted.

소아환자의 깊은 진정요법 하에서 근단변위 판막술을 이용한 거대협소대의 치료

김종빈,윤형배 大韓小兒齒科學會 1999 大韓小兒齒科學會誌 Vol.26 No.1

The mandibular buccal frenum is defined as a fold of mucous membrane at the posterior labial vestibule and attaches the lips and the cheeks to the alveolar mucosa, gingiva, and underlying periosteum. The buccal frenum becomes a problem when its attachment is too colse to the marginal gingiva. It may then pull on healthy gingiva, encourage plaque formation and interfere with tooth brushing. Especially, heavy buccal frenum mucogingivally results in insufficent attached gingiva, inadequate vestibular depth and high frenum attachment and also difficulty in eruption of mandibular premolar. Frenotomy, frenectomy and mucogingival surgery are used in treating heavy buccal frenum. Frenotomy with autogenous free gingival graft has been used popularly because of its stable result. But, it is difficult in younger children because of inadequate donor site, difficulty in making recipient site and behavior management. Frenotomy with apically positioned flap is considered as more efficient way for a very young child with heavy buccal frenum. Additionally, modified deep sedation with N₂O-O₂can be used as an adjunct for the effective treatment outcome. Decrease in muscle pull, adequate width of attached gingiva and increased vestibular depth can be expected from this treatment approach.

진행된 HIV 감염 환자에서 십이지장의 미란성 병변으로 발현한 Mycobacterium genavense 감염 1예

진상만,박종선,김홍빈,오명돈,최강원,김희연,국윤호,김남중 대한감염학회 2007 감염과 화학요법 Vol.39 No.4

Mycobacterium genauense는 최근에 알려진 미코박테륨으로서, 식욕 부진, 체중 감소, 설사, 림프절 병증 등 파종성 Myocobacterium avium-intracellulare complex 감염과 유사한 임상상을 보이며, 위장관 침범을 잘 하는 것으로 알려져 있으나 아직 국내에서 증례는 보고된 바가 없다. 저자들은 진행된 HIV 감염 환자에서 십이지장의 미란성 병변으로 발현한 Mycobacterium genavense 감염 1예를 경험하였기에 문헌 고찰과 함께 보고하는 바이다. 환자는 상복부 동통과 발열, 설사로 내원하였다. 십이지장의 미란성 병변에서 시행한 조직검사에서 항산균이 가득 차있는 거품세포가 관찰되었으며, 이 검체에서 16S rRNA 유전자의 중합연쇄반응 검사를 시행하여 Mycobacterium genavense를 확인하였다. Mycobacterium genavense, first identified in 1990, is known as a pathogen that mimics disseminated Myocobacterium avium-intracellulare complex (MAC) infection with particular propensity for the gastrointestinal tract. In Korea, no case with the organism has been reported. Herein we report a case of Mycobacterium genavense infection that manifested with erosive lesion of duodenum in a patient with acquired immune deficiency syndrome. The patient presented with epigastric pain and fever, diarrhea. Duodenal biopsy showed histiocytic infiltration with numerous acid-fast bacilli. Identification of the mycobacterial isolate by the polymerase chain reaction restriction analysis of 16S rRNA gene revealed Mycobacterium genavense.

재발성 호흡기 유두종증의 임상양상과 보조 치료의 유용성

성명훈,최병윤,진정욱,성원진,박범정,노종렬,김대우,원태빈,김광현 대한이비인후과학회 2001 대한이비인후과학회지 두경부외과학 Vol.44 No.12

Value of Screening Spirometry for Early Diagnosis of Bronchiolitis Obliterans Syndrome in Children After Allogeneic Hematopoietic Stem Cell Transplantation

Yoon, Jong-seo,Chun, Yoon Hong,Lee, Jae Wook,Chung, Nack Gyun,Cho, Bin Wolters Kluwer Health, Inc. All rights reserved. 2015 Journal of pediatric hematology/oncology Vol.37 No.8

Bronchiolitis obliterans syndrome (BOS) is a chronic graft-versus-host disease that occurs in the lungs after hematopoietic stem cell transplantation (HSCT). Serial screening pulmonary function test (PFT) is recommended after transplantation for early diagnosis of BOS. However, little is known about the value or the optimum methods of serial PFT in this context. One hundred and 10 consecutive patients of 6 to 17 years of age at the time of transplantation who underwent allogeneic HSCT were recruited for this study. Screening PFTs were performed 1 week before transplantation and 3, 6, 9, and 12 months after transplantation. When findings of obstructive lung disease were found on PFT, chest high-resolution computed tomography was performed. Of the 110 patients, 5 (4.5%) developed BOS. Of the 5 patients who developed BOS, 2 patients were diagnosed early by screening PFT. However, screening PFT did not allow for early diagnosis of BOS in the other 3 patients because BOS developed after 12 months of transplantation, which is beyond the PFT screening period. In conclusion, trimonthly PFTs performed through 12 months after transplantation in patients who underwent allogeneic HSCT helped in the early diagnosis of BOS; however, there are some limitations to this screening protocol. Future studies will aid in the development of a new screening protocol that can subsequently be evaluated.

LC : Side Population in LX2 Cells Decreased by TGF-β

( Jong Bin Kim ),( Yeon Hwa Ann ),( Seo Young Park ),( Hyeon Gun Jee ),( Hye Ri Kim ),( Jeong Hoon Lee ),( Su Jong Yu ),( Hyo Suk Lee ),( Yoon Jun Kim ) 대한간학회 2013 춘·추계 학술대회 (KASL) Vol.2013 No.1

Aim: Side population (SP) cells are known to be enriched in stem/progenitor-like cells. Transforming growth factor (TGF)-β signaling is associated with ECM production in hepatic stellate cells. We hypothesized that the SP fraction in LX2 cells is associated with ECM deposition, which is regulated through TGF-β signaling. Methods: We investigated the relationship between SP cells and TGF-β signaling in the hepatic stellate cell line LX2. The effects of TGF-β and SB431542 on the SP fraction and expression of collagen type I and phospho-Smad2 was determined. Results: We identified 0.8.3% SP cells in LX2 cells. The growth rate of sorted SP and non-SP cells was similar to that of the original LX2 population, but population of the G0/G1 phase was increased in SP cells. Treatment of LX2 cells with TGF-β decreased the SP fraction in a dose-dependent manner and increased the production of collagen type I. Treatment of LX2 cells with SB431542 blocked the effect of TGF-β on the SP fraction and the expression of collagen type I. We cultured LX2 cells on collagen-coated dishes to observe the effect of ECM deposition on the SP fraction. The growth rate and cell cycle distribution was similar to that observed on normal tissue culture dishes, but the SP fraction was decreased when LX2 cells were cultured on collagen-coated plates. Conclusions: These results show that LX2 cells contain a SP fraction and that TGF-β signaling is involved in the induction of ECM deposition as well as the number of SP cells.

2007 대선과 수도권 투표성향

윤종빈(Jong-Bin Yoon) 한국정당학회 2007 한국정당학회보 Vol.6 No.2

이 연구는 유권자 투표성향을 수도권을 중심으로 살펴본다. 2002년 대선과 그 이후 몇년간의 변화를 분석해 2007 대선을 전망한다. 2002 대선 분석에서 수도권 유권자들은 정치적 지식의 수준이 높고, 지역주의에 덜 영향을 받으며 인물과 능력, 정책과 공약을 상대적으로 더 중요시하고 이념에 따라 선호 후보를 결정하는 경향이 뚜렷하다는 것을 알 수 있다. 2002 대선에서 나타난 이념·세대 간 대결 구도 및 지역주의는 2007년 대선에서는 약화될 것으로 전망된다. 20대 젊은 세대의 대통령과 범여권 지지 철회, 유권자의 중도·보수화 경향, 40대 유권자의 진보세력 지지 철회, 3김의 정치적 퇴장 등이 그 원인으로 분석된다. 그러나 만일 양자 대결구도가 형성되면 지역주의 및 이념 요인이 다시 부상하고 동서대결구도가 구축될 것으로 예측된다. 또한 2007 대선은 도덕성을 중심으로 인물 요인이 크게 작동할 것으로 전망된다. 수도권 유권자들은 후보자의 도덕성과 자질을 포함한 인물 요인을 투표지지 결정의 가장 중요한 기준으로 삼는 특성이 있는 것으로 나타났다. 또한 새로운 이슈나 인물 검증에 민감하고 정당충성도가 약해 선호 후보를 쉽게 바꿀 개연성이 높은 것으로 나타났다. 비록 현재는 경제 변수가 대선의 선거 전략 담론이 되어 이명박 후보가 수도권을 중심으로 전국에서 고른 지지를 받고 있지만, 선거 막바지에 경제 변수를 대체하는 새로운 시대적 요구를 담은 선거 전략이 등장한다면 도덕성의 인물 요인을 중시하는 수도권 유권자들은 민감하게 반응할 것이고 지지 후보를 변경할 수 있을 것이다. 선거를 6개월 여앞둔 시점에서 바라볼 때, 2007 대선은 투표일이 임박하면서 후보자의 경제 문제 실행능력 보다는 도덕성이라는 인물 요인이 좌우할 것으로 전망된다. 전국 선거인수의 약 47%를 차지하는 수도권 유권자의 표심은 선거결과를 좌우하는 중요한 요인이 될 것이다. This paper, first of all, analyzes voting behavior of the metropolitan electorates in the 2002 presidential election. Based on the further testing of the following four years, this study foresees the 2007 presidential election. It is very hard to predict the results of the upcoming election, considering the fluctuating Korean electoral process. However, it may be maintained that the upcoming election will be significantly different from the previous one in a sense that it will not be strongly influenced by ideology, generation, and regionalism unless a bipolar system of competition is being made. It can be argued that the 2007 presidential election will be mainly determined by candidate-oriented factors, especially individual morality, rather than by candidate capabilities of economy recovery. In this process, the voting choice of metropolitan areas, consisted of almost a half of total eligible voters, will greatly influence voting turnout as a whole.