인산칼륨배합세치제의 상아질지각과민완화효과

손재범,성진효,김동기 대한구강보건학회 2003 大韓口腔保健學會誌 Vol.27 No.1

The desensitizing toothpaste which is containing potassium phosphate, sodium fluoride, ursodesoxycholic acid and tocopherol acetate was compared with other silica-base toothpastes for the treatment of dentinal hypersensitivity in a double-blind study. Of these, one acted as negative control containing only 1,000ppm of fluoride, another acted as positive control containing 5% postassium nitrate and 1,000ppm of fluoride, and the other acted experiment contained 2% monobasicpotassium phosphate, 3% dibasicpotassium phosphate, 0.02% UDCA, 0.05% tocopherol acetate and 1,000ppm of fluoride. 96patients who have dentinal hypersensitivity were randomly allocated to use those toothpastes for 8 weeks. Sensitivity was scored according to the response to thermal stimuli, tactile, evaporative stimuli. Recordings were made at baseline,1,3,5 and 8week. The statistical comparison showed that sensitivity duration of experimental group was reduced significantly compared to negative control group and positive control group(p<0.05). The clinical findings would be consistent with the in vitro observation that the experimental toothpaste occluded open dentinal tuble more effectively and increase the hardness of teeth more highly than positive control and negative control toothpastes.

맹출장애가 있는 하악대구치의 임상적 관리

손우성,이해경,남형진,강상욱,송효경,김성식 부산대학교 병원 암연구소 2009 부산대병원학술지 Vol.- No.25

혼합 치열기 어린이의 치은 섬유종증

한효정,최병재,김진,김성오,손홍규 大韓小兒齒科學會 2004 大韓小兒齒科學會誌 Vol.31 No.4

치은 섬유종증은 유리 치은과 부착 치은이 점진적으로 증식되는 비염증성 질환이다. 대부분 가족력이 있으며 영구치 맹출과 함께 발병하지만 유치 맹출 시기에, 드물게 출생 시부터 나타나기도 한다. 본 6세 여아의 경우 태어날 때부터 치은의 일부가 증식되어 있었고 가족력 및 치은 증식을 유발하는 약물을 복용한 병력은 없었다. 구강 내 검진 시 섬유성 치은 증식이 관찰되어 절제 생검을 시행하였고 그 결과 치은 섬유종증으로 진단하였다. 치은 섬유종증의 치료는 치은 절제술과 철저한 구강 위생의 관리이다. 그러나 치료 후 재발성 때문에 치료 시기에 대해서는 논란 중이다. 일반적으로 영구치가 모두 맹출 한 이후에 치료할 것을 추천하지만 조기 치료는 구강의 기능 및 환아의 심미적, 심리적인 문제점을 개선시켜 주는 장점이 있다. Gingival fibromatosis is a non-inflammatory oral disease, characterized by slowly progress enlargement of the free and attached gingiva. Gingival fibromatosis may have familial tendency. Gingival enlargement usually begins with the eruption of the permanent dentition but can also develop with the eruption of the primary dentition. In this case, a 6-year-old female had gingival enlargement at birth. There was no familial, medical and pharmacologic history of gingival overgrowth. Treatment is gingivectomy with a rigorous program of oral hygiene. Recurrence of gingival fibromatosis may well be inevitable. Therefore there is no general aggrement as to the timing of surgical intervention. Generally the best time is when all the permanent teeth have erupted. However early intervention can improve oral function and esthetic and psychologic effect.

점포내 VMD요소가 SPA 브랜드 정체성에 미치는 영향

김소영, 손지훈, 심효진, 신동훈, 정일호, 홍동우, 김은영 충북대학교 생활과학연구소 2013 생활과학연구논총 Vol.17 No.2

This study was to examine the effect of VMD factors on brand identity for SPA brands. As brand stimulus, four SPA brands(e.g., Basic House, Codes combine, Uniqlo, Zara) were selected by pretest. For collecting data, a self-administered questionnaire was developed based on the literatures and intercept survey was conducted. A total 508 usable responses were obtained from consumers who shopped at the selected brands' stores. For data analysis, descriptive statistics, factor analysis, and regression analysis were used. As perceived by consumers, VMD consisted of seven factors: lightening, scent, color, layout, music, window display, and item presentation. The VMD factor was significantly related to brand identity for the SPA brands. Specifically, brand awareness was predicted by color, layout and item presentation; brand association strength was predicted by color, layout, and widow display; favorable brand association was predicted by item presentation; salience of brand association was predicted by color and music; and brand image association was predicted by color, layout, music, and item presentation. Thus, this study discussed a managerial implication for SPA retailers to develop a visual merchandising strategy in the competitive marketplace.

철 산화균(Thiobacillus ferrooxidans)을 이용한 황화수소 제거-온도변화에 따른 황화수소 제거효율변화

박양호,손효진,김려화,권규혁,이중헌 한국공업화학회 2002 응용화학 Vol.6 No.2

Effects of temperature on hydrogen sulfide removal efficiency has been studied in this research. Two reactors which combined iron oxidization reactor and reduction reactor were manufactured. Iron oxidation reactor was used to oxidize Fe(II) to Fe(III) with Thiobacillus ferrooxidans and the hydrogen sulfide was oxidized to make element sulfur with the reduction of iron. The optimal temperature for the iron oxidation was 30℃ however that of iron reduction was 40℃. From this result, the optimal continuous operation conditions has been determined.

고정화 세포를 이용한 황화수소 제거공정 최적화

박양호,손효진,김경주,권규혁,이중헌 한국공업화학회 2003 응용화학 Vol.7 No.1

In this study, the hybitd reactor has used to remove H_2S from the toxic gas. Since the oxidation and reduction reactors were combined, theri sizes were important to stabilize developed process. The optimal sizes of oxidation and reduction reactors were determined considering iron oxidation rate and H_2S removal rate. The optimal ratio of reactor size was 4 L for oxidation reactor to 1 L for reduction reactor.Immobilized Thiobacillus ferrooxidans has been developed to minimize the size of oxidation reactor. Since the immobilized cell enhanced the oxidation rate, it was possible to incrase H_2S removal efficiency. It was possible to incerase operation time because immobilized cell can survie lger than free cell.

압력용기의 설계기준 및 손상 평가

오환섭,정효진,박상필,손두익 한국공작기계학회 2005 한국공작기계학회 춘계학술대회논문집 Vol.2005 No.-

The damage of the pressure courage by degradation can become the reason of unexpected break down or failure accident and it is very important because safety accident, the production loss, environmental pollution, social problems are occur. Consequently The result to investigat of failure accident for domestic pressure vessel, the factor of degradation is SCC, Sorrosion, Cavity, Crack

초등학교 고학년 학생의 장애아동에 대한 인식 조사

김보람,김호영,손유라,오진주,윤슬기,이효정,장문영 대한감각통합치료학회 2011 대한감각통합치료학회지 Vol.9 No.1

목적 : 초등학교 고학년 학생의 장애아동에 대한 인식을 알아보는 것이다. 연구방법 : 연구 대상은 김해시에 소재한 통합교육을 실시하지 않는 초등학교의 4, 5, 6학년의 비장애 아동이었다. 연구 기간은 2008년 10월 2일부터 10월 17일까지였으며, 설문지를 사용하였다. 설문지의 하위 영역은 사귐, 활 동, 학업 영역의 세 부분으로 각 10문항으로 이루어져 있으며 SPSS 12.0을 사용하여 분석하였다. 결과 : 장애아동에 대한 인식조사 결과 첫째, 성별에 따른 인식은 남학생보다 여학생의 평균 점수가 높았으나 통계 적으로 유의미한 차이는 없었다. 둘째, 학년에 따른 인식은 4학년의 평균 점수가 가장 높았고 6학년이 가장 낮았으 며 통계적으로 유의미한 차이가 있었다(F=3.546, p<0.05). 셋째, 장애인 접촉 유무에 따른 인식은 접촉 경험이 없 는 학생이 있는 학생보다 평균점수가 높았으나 통계적으로 유의미한 차이는 없었다. 결론 : 비장애학생의 장애아동에 대한 인식은 학년에 따라 차이가 있었다. 본 연구는 작업치료사들에게 장애아동에 대한 또래집단의 인식에 대한 정보를 제공함으로써 학교환경에 대한 이해를 도울 수 있을 것이다. Objective : The purpose of this study was to investigate attitude of grade-schoolers toward children with disabilities. Methods : The subjects of this study were grade-schoolers who have not received an inclusive education in Gim-hae. The study was surveyed from October second to 17th in 2008. The survey was categorized into three parts; comradeship, activity, and study. Each part of the survey consists of 10 questions. Data were analyzed by SPSS (version 12.0). Results : The results were as follows; First, the attitude of girls toward disabled students was non-significant compared to boys. Second, the order of attitude degree in grade of students was 4, 6, and 5. The attitude toward children with disabilities showed statistically significant difference according to grade(F=3.546, p<0.05). Third, the attitude of students who have experience of contact with people with disabilities was non-significant compared to non-experienced students. Conclusion : In conclusion, therefore peer groups in lower class levels showed more positive attitude toward the children with disabilities. The result will be useful information for understanding disabled children and making positive attitude. Also it is expected that occupational therapists help disabled children to participate in school life successfully using these information.

Ascorbate Peroxidase 유전자의 도입에 의한 식물의 형질전환

이인애,이효신,배은경,김기용,이병헌,손대영,조진기 Plant molecular biology and biotechnology research 2002 Plant molecular biology and biotechnology research Vol.2002 No.-

This study was conducted to obtain the transformed tobacco (Nicotiana tubacum) plants with cytosolic ascorbate peroxidase gene(ApxSC7) using Agrobacterium tumefaciens LBA4404. A cDNA encoding the cytosolic ascorbate peroxidase of strawberry, ApxSC7, was introduced into tobacco plants via Agrobacterium-mediated gene transfer system. The expression vector, pIG-AP8, harboring ApxSC7 gene was used for production of transgenic tobacco plants. A large number of transgenic plants were regenerated on a medium containing hygromycin. Integration of ApxSC7 gene was confirmed by PCR and Southern blot analyses with genomic DNA. Northern blot analyses revealed that the pIGap8 gene was constitutively expressed.

Bupivacaine과 ropivacaine이 Xenopus oocyte에 발현된 HERG 전류에 미치는 영향

김국성,이규승,김효신,손숙진,이상도,김광진,전병화,김윤희,박진봉 충남대학교 의과대학 의학연구소 2003 충남의대잡지 Vol.30 No.1

Bupivacaine is an amide-type local anesthetic widely used for regional anesthesia. Ropivacaine is developed as a less cardiotoxic alternatives to bupivacaine. In the present study, we have analyzed the effects of bupivacaine and ropivacaine on HERG currents expressed in Xenopus oocytes. Bupivacaine and ropivacaine(3∼1,000μM) blocked HERG currents in a concentration dependent manner. EC_(50) was 26.1±3.1μM(n_(R) 0.65±0.04) and 43.5±7.9μM(n_(H) 0.99±0.13) in bupivacaine and ropivacaine, respectively. Bupivacaine and ropivacaine did not affect the activation and deactivation kinetics of HERG channels. However, the drugs decreased the slope conductance measured from fully activated current-voltage relationship curves. These results suggest that bupivacaine and ropivacaine have a similarinhibitory effect on HERG channels, which could be a possible cellular mechanism of LQT or ventricular arrythmia by the drugs.