http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Hyein Jung,Hyein Shim,Jiwon Jeong,Jungeun Lee,Sangah Shin 한국식품영양과학회 2021 한국식품영양과학회 학술대회발표집 Vol.2021 No.10
Alcohol abuse is one of the health risk factors worldwide. It is known that the presence of alcoholic liver disease (ALD) has the greatest correlation with alcohol consumption. A cross-sectional analysis was conducted to investigate the alcohol consumption and nutritional status of ALD patients among Korean adults. A total of 156,790 subjects, 2,226 (1,921 males, 305 females) in the ALD group, and 154,564 (50,593 males, 103,971 females) in the normal group were included in the final analysis. Alcohol and nutrient intakes were assessed using a validated food frequency questionnaire. The ALD was defined as heavy alcohol consumption (male >40 g/day, female >20g/day) and elevated level in the liver function test. It was confirmed that ALD patients exhibited a higher total alcohol intake, the proportion of heavy drinkers, and increased total energy intake compared to the normal group, and tended to lack micronutrient intake through dairy and plant-based foods. Based on the results of the study, it is recommended to reduce the amount and frequency of alcohol consumption and to consume sufficient vitamins and minerals through dairy and plant-based foods for patients with ALD.
Langmuir-Blodgett Films of Perfluoroalkyl Monomaleate Copolymers on Porous Substrate
Hyein Jeong,Burm-Jong Lee,Young-Soo Kwon Korean Chemical Society 1994 Bulletin of the Korean Chemical Society Vol.15 No.8
Stable polyion-complexed polymeric monolayers were prepared by spreading perfluoroalkyl monomaleate copolymers, $C_2F_8MA-VE_2$ and $C_2F_8MA-VE_3$, on a aqueous poly(allylamine) subphase. The monolayer properties have been studied by the surface pressure-area (${\pi}$-A) isotherms. The $C_2F_8MA-VE_3$ containing longer oligoethyleneglycol pendant showed more expanded monolayer phase than the $C_2F_8MA-VE_2$. The polyion-complexed monolayers were transferable on various substrates, and the resulting Langmuir-Blodgett (LB) films were characterized by FT-IR spectroscopy and scanning electron microscopy (SEM). Two-dimensional crosslinking to form a polymer network was achieved by amide formation through heat treatment under vacuum with concurrent removal of perfluoroalkyl tails. SEM observation of this film on a porous membrane filter showed that the four layer film was sufficiently stable to cover the filter pore size of 0.1 ${\mu}$m. The $C_2F_8MA-VE_3$ revealed better covering capability than the $C_2F_8MA-VE_2$. Immersion of this film in water or in benzene did not cause any change in its appearance and in Fl-IR spectra.
Ju Hyein,Yun HongDuck,Kim YongHwan,Nam Yun Ji,Lee Seungun,Lee Jinwon,Jeong Seon Min,Heo Jinbeom,Kwon Hyungu,Cho You Sook,Jeong Gowun,Ryu Chae-Min,Shin Dong-Myung 생화학분자생물학회 2023 Experimental and molecular medicine Vol.55 No.-
Glutathione (GSH), an abundant nonprotein thiol antioxidant, participates in several biological processes and determines the functionality of stem cells. A detailed understanding of the molecular network mediating GSH dynamics is still lacking. Here, we show that activating transcription factor-2 (ATF2), a cAMP-response element binding protein (CREB), plays a crucial role in maintaining the level and activity of GSH in human mesenchymal stem cells (MSCs) by crosstalking with nuclear factor erythroid-2 like-2 (NRF2), a well-known master regulator of cellular redox homeostasis. Priming with ascorbic acid 2-glucoside (AA2G), a stable vitamin C derivative, increased the expression and activity of ATF2 in MSCs derived from human embryonic stem cells and umbilical cord. Subsequently, activated ATF2 crosstalked with the CREB1-NRF2 pathway to preserve the GSH dynamics of MSCs through the induction of genes involved in GSH synthesis (GCLC and GCLM) and redox cycling (GSR and PRDX1). Accordingly, shRNA-mediated silencing of ATF2 significantly impaired the self-renewal, migratory, proangiogenic, and anti-inflammatory capacities of MSCs, and these defects were rescued by supplementation of the cells with GSH. In addition, silencing ATF2 attenuated the ability of MSCs to alleviate airway inflammatory responses in an ovalbumin-induced mouse model of allergic asthma. Consistently, activation of ATF2 by overexpression or the AA2G-based priming procedure enhanced the core functions of MSCs, improving the in vivo therapeutic efficacy of MSCs for treating asthma. Collectively, our findings suggest that ATF2 is a novel modulator of GSH dynamics that determines the core functionality and therapeutic potency of MSCs used to treat allergic asthma.
예비유아교사의 다문화 감수성과 다문화 교수효능감의 관계연구
정혜인(Jeong, Hyein),김진영(Kim, Jinyoung) 학습자중심교과교육학회 2018 학습자중심교과교육연구 Vol.18 No.7
본 연구는 예비유아교사를 대상으로 그들의 다문화 감수성과 다문화 교수효능감의 관계를 분석하는 것에 목적을 두고 있다. 본 연구의 대상은 D 광역시에 위치한 4년제 유아교육과 1-4학년 재학생 240명이다. 본 연구를 위하여 Chen과 Strosta(2000)가 개발한 다문화 감수성 척도와 옥장흠(2009)이 개발한 다문화 교수효능감 척도를 사용하였다. 다문화 감수성 척도의 하위변인은 상호작용참여, 문화차이존중, 상호작용 자신감, 상호작용 향유, 상호작용 주의로 구성되어 있다. 연구문제는 첫째, 예비유아교사 중 다문화 감수성이 높은 집단과 낮은 집단은 다문화 교수효능감에 차이가 있는가? 둘째, 예비유아교사 중 다문화 감수성 하위변인이 다문화 교수효능감을 예측하는 설명력은 어떠한가? 이며 이를 분석한 결과는 다음과 같다. 첫째, 다문화 감수성이 높은 집단과 낮은 집단 사이에는 다문화 교수효능감의 평균차이가 통계적으로 유의하게 나타났다. 즉, 다문화 감수성이 높은 집단의 다문화 교수효능감이 다문화 감수성이 낮은 집단보다 높게 나타났다. 둘째, 다문화 감수성 하위변인 이 다문화 교수효능감 전체에 대한 설명력은 45.0%로 분석되었으며 하위 변인 중, 상호작용 참여가 가장 많은 설명력을 지니고 있었다. 본 연구 결과는 다문화 교수효능감 향상을 위한 예비교사 및 교사를 위한 교육내용 구성에 상호작용 참여하는 방 안에 대한 고려를 시사하고 있다. The study aims to explore the effect of preservice early childhood teachers’ multicultural sensitivity on their multicultural teaching efficacy. Research for this study focuses on 240 perservice teachers enrolled in early childhood education at a private university in D city, South Korea. This study addresses these topics by exploring a key issue: it illustrates how preservice teachers’ multicultural sensitivity and multicultural perception are influence on their multicultural teaching efficacy. The data for this research was obtained through the participants’ surveys. Statistical analysis of the collected data was carried out with SPSS 22.0 program. The results of this research are as follows. First, the participant preservice teachers’ multicultural sensitivity is influenced on their multicultural teaching efficacy. Second, Among multicultural sensitivity’s subvariables, respect for interaction engagement to interact with others significantly influenced multicutural teaching efficacy.
자폐 스펙트럼 장애 치료효과 평가를 위한 미니척도 개발
정혜인(Hyein Jeong),김봉석(Bongseog Kim) 대한사회정신의학회 2023 사회정신의학 Vol.28 No.2
목적 : 자폐스펙트럼장애(ASD)의 유병률이 증가하며 효과적인 진단 및 선별도구가 필요하다. 본 연구는 현재 사용되는 여러 평가도구는 임상 현장에서 사용하기에 제한이 있어 간편하게 사용 가능한 미니척도를 개발하고 그 유용성을 평가하고자 한다. 방법 : 정신건강의학과 전문의에게 ASD를 진단받은 아동 20명에 대해 Theraplay를 시행하여 치료 전 후 얻은 임상적 정보를 바탕으로, 사회적 의사소통설문지(K-SCQ)와 미니척도를 평정하여 두 점수 간의 상관관계를 확인한다. 결과 : 미니척도에 대해 요인분석을 시행하고, 요인분석 결과에 따라 미니척도의 3개의 하위항목과 K-SCQ의 하위점수에 대해 상관관계를 확인하였다. 미니척도의 하위척도가 K-SCQ의 각 하위척도 중 제한적/반복적 행동을 제외하고는 모두 유의미한 상관관계가 있었다(p<0.05). 결론 : 본 연구에서 제시한 MINI 척도에 대해 신뢰도와 타당도를 추가적으로 평가하여 임상 현장에서 사용을 고려해볼 수 있을 것이다. Objectives: The growing prevalence of autism spectrum disorder (ASD) raises a need for effective diagnosis and select instruments. Recognizing that several assessment tools that are currently in use have limitations for the clinical field, this study aims to develop a mini scale of simple availability and assess its usefulness. Methods: The study applied Theraplay to 20 children diagnosed with ASD by a neuropsychiatry specialist, rated them with the Korean Version of Social Communication Questionnaire (K-SCQ) and the MINI scale based on clinical information obtained before and after therapy, and examined correlations between their two scores. Results: Following a factor analysis for MINI scale results, the study checked the correlations between its three subitems and the subscores of K-SCQ according to the factor analysis results. There were significant correlations between the subscales of MINI and those of K-SCQ except for restricted/repeated behavior (p<0.05). Conclusion: The application of the MINI scale proposed in this study can be considered for use in the clinical field based on an additional evaluation of its reliability and validity.
한국어 문장이해에서 다의어와 동음이의어의 표상과 처리: ERP 연구
정혜인 ( Hyein Jeong ),윤홍옥 ( Hongoak Yun ),홍우평 ( Upyong Hong ) 한국외국어대학교 언어연구소 2015 언어와 언어학 Vol.0 No.68
This study iNvestigated the differeNces of polysemy aNd homoNym duriNg oNliNe seNteNce compreheNsioN iN KoreaN. UsiNg the ERP paradigm, we maNipulated the coNteNt of coNtext to be biased iN a way that the seNses of polysemy aNd homoNym were to be domiNaNt, subdomiNaNt or Neutral. IN each coNtext coNditioN, we also maNipulated the meaNiNg of the seNteNce-fiNal verb was to be coNgrueNt or iNcoNgrueNt to the coNtext. At the verb regioN, we observed the coNgrueNcy effect emerged as the N400 aNd the P600 iN the processiNg of homoNym but appeared as the P600 iN that of polysemy. These results supported the claim of the core meaNiNg approach such that the multiple seNses of polysemy share their core meaNiNgs iN their siNgle represeNtatioN, uNlike the wide agreemeNt that the multiple seNses of homoNym are separately represeNted.