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김재홍,윤기범,박평원,김영진,전경민,김영태,김중환,곽호,구상완,송민석,유옥,지혜구,김동원,문상은,박영립,정승호,성범진,성순제,엄주용,황정열,이기홍,이주협,전태진 대한화학요법학회 1994 대한화학요법학회지 Vol.12 No.1
The prevalence of PPNG among pretreated gonorrhea cases isolated at the STD clinic of Choong-Ku Public Health Center in Seoul has been studied and reported annually since 1981. In 1991, 123 strains of N.gonorrhoeae were isolated, among which 58(47.1%) were PPNG. In 1992, 98 starains of N.gonorrhoeae were isolated, among which 51(52.0%) were PPNG. In all, 109(49.3%) strains were found to be PPNG among 221 strains isolated between 1991-1992. The prevalence of PPNG in Seoul showed increased tendency till 1989, thereafter, it has been stationary or slightly decreasing.
Eom Ji-Eun,Kim Gun-Dong,Kim Young In,Lim Kyung min,Song Ju Hye,Kim Yiseul,Song Hyeon-Ji,Shin Dong-Uk,Lim Eun Yeong,Kim Ha-Jung,Kim Sung Hoon,Lee Deuk Sik,Lee So-Young,Shin Hee Soon 한국미생물·생명공학회 2023 Journal of microbiology and biotechnology Vol.33 No.5
Chronic obstructive pulmonary disease (COPD), one of the leading causes of death worldwide, is caused by repeated exposure to harmful matter, such as cigarette smoke. Although Lilium longiflorum Thunb (LLT) has anti-inflammatory effects, there is no report on the fermented LLT bulb extract regulating lung inflammation in COPD. Thus, we investigated the protective effect of LLT bulb extract fermented with Lactobacillus acidophilus 803 in COPD mouse models induced by cigarette smoke extract (CSE) and porcine pancreas elastase (PPE). Oral administration of the fermented product (LS803) suppressed the production of inflammatory mediators and the infiltration of immune cells involving neutrophils and macrophages, resulting in protective effects against lung damage. In addition, LS803 inhibited CSE- and LPS-induced IL-6 and IL-8 production in airway epithelial H292 cells as well as suppressed PMA-induced formation of neutrophil extracellular traps in HL-60 cells. In particular, LS803 significantly repressed the elevated IL-6 and MIP-2 production after CSE and LPS stimulation by suppressing the activity of the nuclear factor kappa-light-chainenhancer of activated B (NFκB) in mouse peritoneal macrophages. Therefore, our results suggest that the fermented product LS803 is effective in preventing and alleviating lung inflammation.
콩나물의 재배기간에 따른 NDF에 결합된 미량 무기질의 변화와 추정이용률
엄지혜(Ji Hye Eom),은정화(Jeong Hwa Eun),최희정(Hee Jeong Choi),김대진(Dae Jin Kim) 한국식품영양과학회 2009 한국식품영양과학회지 Vol.38 No.3
본 연구는 한국인이 많이 섭취하는 채소류의 하나인 콩나물을 재배기간 1, 3, 5일에 따라 자엽과 배축으로 분리하고 cell wall에 결합된 Cu, Fe, Mn, Zn의 함량을 측정하여 간과하기 쉬운 미량 무기질의 이용률을 추론하고자 실시하였다. 자엽의 NDF에 결합된 미량 무기질은 Mn을 제외하고 모두 5일째에 가장 적게 결합되어 있었고, 배축에서는 Cu와 Mn이 5일째에 많이 결합되어 있었으며 Fe과 Zn은 재배기간이 증가할수록 결합 정도가 유의적으로 감소하였다. 또한 자엽과 배축에서의 추정이용률을 보면 자엽에서 Cu, Fe 및 Zn은 재배기간이 증가할수록 높은 이용률을 보였고 Mn은 1, 3, 5일째 모두 99% 이상의 매우 높은 이용률을 보여 콩나물자엽에 있어서 특히나 Mn 자원으로서의 그 이용이 기대될것으로 판단되었다. 배축에서는 Cu와 Fe이 다소 낮은 이용률을 보였지만 Mn과 Zn은 3일째에 95% 이상으로 추정이용률이 높았다. This study was conducted to determine contents and estimated availabilities of trace minerals (Cu, Fe, Mn, Zn) in soybean sprouts depending on culture periods such as 1, 3 and 5 days. The proportional changes of Cu estimated availability in cotyledon were between 57.31 and 98.34%, between 63.69 and 82.56% for Fe, 99.19 and 99.82% for Mn and 48.60 and 94.56% for Zn, respectively, based on dry matter. The estimated availabilities of Cu, Fe, Mn, and Zn in hypocotyl were between 34.63 and 56.0%, 20.74 and 40.33%, 86.5 and 95.88%, and 96.11 and 96.61%, respectively, on dry matter basis.
Korean Gastric Cancer Association Nationwide Survey on Gastric Cancer in 2014
Eom, Bang Wool,Ahn, Hye Seong,Lee, In Seob,Min, Jae-Seok,Son, Young Gil,Lee, Sang Eok,Kim, Ji Hoon,Lee, Se-Youl,Kim, Jie-Hyun,Ahn, Sang-Hoon,Kim, Hyung-Ho,Kim, Young-Woo The Korean Gastric Cancer Association 2016 Journal of gastric cancer Vol.16 No.3
Purpose: The Korean Gastric Cancer Association (KGCA) has conducted nationwide surveys every 5 years, targeting patients who received surgical treatment for gastric cancer. We report the results of the 2014 nationwide survey and compare them to those of the 1995, 1999, 2004, and 2009 surveys. Materials and Methods: From March 2015 to January 2016, a standardized case report form was sent to every member of the KGCA via e-mail. The survey consisted of 29 questions, regarding patient demographics as well as tumor-, and surgery-related factors. The completed data forms were analyzed by the KGCA information committee. Results: Data on 15,613 patients were collected from 69 institutions. The mean age was $60.9{\pm}12.1$ years, and the proportion of patients more than 70 years of age increased from 9.1% in 1995 to 25.3% in 2014. Proximal cancer incidence steadily increased from 11.2% in 1995 to 16.0% in 2014. Early gastric cancer incidence consistently increased and accounted for 61.0% of all cases in 2014. The surgical approach was diversified in 2014, and 7,818 cases (50.1%) were treated with a minimally invasive approach. The most common anastomosis was Billroth I (50.2%) after distal gastrectomy, and the proportion of Roux-en-Y anastomoses performed increased to 8.6%. Conclusions: The results of this survey are expected to be important data for future studies and to be useful for generating a national cancer control program.