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윤복연,문덕환,박명희,황용식,함성애,손병철,김대환,이창희,김휘동,이채언 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.5
Objective : This study was conducted to prepare the fundamental data on heavy metal concentration in hair permanents agents and to prevent the health impairment due to heavy metal. Methods and Material : The author determined of 5 heavy metals(Pb, Cr, Mn, Ni, and Cu) concentration hair permanent agents in the market with flameless atomic absorption spectrophotometer. Results : The results were as follows: 1. The geometic mean concentrations of total subjects were 0.04㎍/g for Pb, 0.09㎍/g for Cr, 0.06㎍/g for Mn, 0.03㎍/g for Ni, and 0.04㎍/g for Cu. 2. The most highest mean concentrations of heavy metals in hair permanent agents by using type were Cr for wave agent and straight cream agent, Cu for setting iron agent, Cr and Cu for coating perm agent. 3. Metal most hlghest mean concentrations of heavy in hair permanent agents by type of color was green for Cu. 4. The mean concentration of Cu among 5 heavy metals in hair permanent agents by marker was most highest. 5. There was most statistically significant difference on mean concentration in hair permanent agents between domestic and foreign products. 6. The exposure amount of heavy metal concentration by one time using the permanent agent were 4.O㎍ for Pb, 9.O㎍ for Cr, 6.0㎍ for Mn, 3.O㎍ for Ni and 4.0㎍ for Cu. Conclusion : As above results author suggest to prepare the preventive program of health impairment due to heavy metal by long term chronic exposure to who were using the hair permanent agents hair designer and customers.
류복희(Bok-Hee Ryu),문광덕(Kwang-Deog Moon),김성달(Sung-Dal Kim),손태화(Tae-Hwa Sohn) 한국식품영양과학회 1990 한국식품영양과학회지 Vol.19 No.2
성숙중 토마토 과실의 연화현상과 관련한 무기성분들의 함량 및 존재형태의 변화와 호흡량, 경도의 변화를 측정하였다. 성숙에 따라 토마토 과실의 호흡량은 감소하다가 개화후 42일경부터 증가하여 49일경에 climacteric maximum에 도달하였으며 그후 감소하였다. 토마토 과실의 경도변화는 개화후 45일까지는 큰 변화가 없었으나 그후 급격히 감소하였다. 토마토 과실의 무기성분으로 K, Ca, Mg의 함량은 높았으나 Zn, Fe, Mn, Cu 등은 소량으로 함유되어 있었다. 개화후 45일 이후 soluble Ca, Mg 및 K은 성숙에 따라 증가하였고 bound Ca, Mg은 크게 감소하였으며 그 밖의 다른 무기성분은 성숙중에 큰 변화를 나타내지 않았다. This study was conducted to investigate the relation of softening with the mineral components during ripening of tomato fruits. The mineral contents of Ca, K, Mg, Zn, Fe, Mn and Cu and its existence form, respiratory rate and hardness during ripening were evaluated. The respiratory rate of tomato fruits was decreased until 42 days after anthesis and then increased the climacteric maximum was found on 49 days after anthesis, then decreased. The hardness of tomato fruits during ripening did not change greatly until 45days after anthesis, then decreased markedly. The major mineral components of tomato fruits were K, Ca and Mg. Zn, Fe, Mn and Cu were the minor components. The contents of soluble Ca, Mg and K increased markedly and those of bound Ca and Mg decreasd markedly after 45days during ripening. However other components were not changed greatly.
An analysis of the number of liver and kidney transplantations during COVID-19 pandemic in Korea
Jung-Ja Hong,Shin Hwang,Deog-Bok Moon,Young Hoon Kim,Sung Shin,In-Ok Kim,Sae-Rom Lee,Ah-Young Lee,Jiwon Woo 대한이식학회 2021 Korean Journal of Transplantation Vol.35 No.4
Background: The severity of the coronavirus disease 2019 (COVID-19) pandemic has discouraged organ donation. However, the prevalence of COVID-19 in Korea was much lower in comparison to Western countries. With this, the authors decided to determine the real-world impact of COVID-19 on organ donation and transplantation in Korea. Methods: The number of kidney transplantations (KTs) and liver transplantations (LTs) performed in 2020 were compared with those in 2019 using the Korean Network for Organ Sharing database and Asan Medical Center (AMC) database. Results: The annual number of deceased donors (DDs) was 450 in 2019 compared to 478 in 2020. Monthly DD number was 37.5±5.9 in 2019 and 39.8±4.4 in 2020 (P=0.284). Annual number of DD kidney transplant (DDKT) was 794 in 2019 and 848 in 2020, and monthly number was 66.1±10.4 in 2019 and 70.7±9.8 in 2020 (P=0.285). The annual number of DDLT was 391 in 2019 and 395 in 2020, and the monthly number was 32.6±5.7, 2019 and 32.9±4.7 in 2020 (P=0.877). The annual number of living donor (LD) KT was 2,293 in 2019 and 1,432 in 2020, and the monthly number was 191.1±19.5 in 2019 and 119.3±11.7 in 2020 (P<0.001). Annual number of living donor LDLT was 1,577 in 2019 and 1,146 in 2020, and monthly number was 131.4±18.1 in 2019 and 95.5±8.0 in 2020 (P<0.001). In the AMC, not all types of KT and LT changed significantly. Conclusions: The results of this study indicate that the number of DD organ transplantations remained stable in Korea in 2020, but the number of LD organ transplantations was significantly reduced. However, the number of organ transplantations did not change in the AMC.
Resection of Pulmonary Metastases from Hepatocellular Carcinoma following Liver Transplantation
Shin Hwang,Yong-Hee Kim,Dong Kwan Kim,Chul-Soo Ahn,Deog-Bok Moon,Ki-Hun Kim,Tae-Yong Ha,Gi-Won Song,Dong-Hwan Jung,Hyeong Ryul Kim,Gil-Chun Park,Yong-dong Yu,Sung-Gyu Lee 한국간담췌외과학회 2010 한국간담췌외과학회 학술대회지 Vol.2010 No.4
Dong-Ju Kim,Joong-Ho Kwon,정용진,Kwang-Deog Moon,Hye-Jin Kim,Seon-Min Jeon,Mi-Kyung Lee,Yong Bok Park,Myung-Sook Choi 한국식품영양과학회 2008 Journal of medicinal food Vol.11 No.2
The current study investigated the antidiabetic effect of chungkukjang, a widely used traditional Korean soy-bean fermentation food, in a type 2 diabetic animal model, C57BL/KsJ-db/dbmice. After a 2-week acclimation period, thedb/dbmice (male, 5 weeks old) were divided into three groups: diabetic control (AIN-76 diet), chungkukjang (5 g/100 g ofdiet), and rosiglitazone (0.005 g/100 g of diet). The supplementation of chungkukjang induced a significant reduction of bloodglucose and glycosylated hemoglobin level, and it improved insulin tolerance compared to the diabetic control group. Plasmaand pancreatic insulin levels of the chungkukjang-supplemented group were significantly higher than those of the diabeticcontrol mice, and the plasma glucagon level was also significantly different. The supplementation of chungkukjang and rosigli-tazone significantly elevated hepatic glucokinase activity with a simultaneous reduction of glucose-6-phosphatase andphosphoenolpyruvate carboxykinase activity in the db/dbmice compared to the diabetic control mice. In addition, the chungkuk-jang-supplemented group had an increased hepatic glycogen content compared to the diabetic control and rosiglitazone-sup-plemented groups. Consequently, these results suggest that chungkukjang may be beneficial in improving insulin resistanceand hyperglycemia in type 2 diabetic animals that are partly medicated by the regulation of hepatic glucose enzymes and in-sulin sensitivity in peripheral tissues.
TAK, EUNYOUNG,HWANG, SHIN,LEE, HAN CHU,KO, GI-YOUNG,AHN, CHUL-SOO,YOON, YOUNG-IN,LIM, YOUNG-SUK,JUN, DAE-YOUNG,KIM, KI-HUN,SONG, GI-WON,MOON, DEOG-BOK,RYOO, BAEK-YEOL,KIM, NAYOUNG,LEE, SUNG-GYU Potamitis Press 2016 Anticancer research Vol.36 No.11
<P>Background/Aim: We investigated the expression of hepatitis B virus (HBV) covalently closed circular DNA (cccDNA) and HBV X protein (HBx) in human hepatocellular carcinoma (HCC) and evaluated the effect of high-concentration nucleos(t)ide analogs (NUCs) on liver tumor cell lines. Materials and Methods: This study consisted of three parts: part I used human blood and non-tumor liver tissues; part II used human HCC and adjacent liver tissues; and part III used an HBV-expressing liver tumor cell line. Results: There were close correlations among blood and liver HBV DNA and liver cccDNA. HBV cccDNA and HBx were highly up-regulated in HCC compared to adjacent liver tissues despite NUC therapy. HBV cccDNA and HBx were highly up-regulated in the cccDNA-expressing HepG2.2.15 cell line. Their expression was down-regulated and apoptosis was induced by a very high concentration of NUCs in dose-and time-dependent manner. Conclusion: Very high concentrations of NUCs may have a novel potential to kill replicating HBV-expressing liver tumor cells.</P>