Recent Developments in the Effects of Different Dopants on the Structure and Property of Lithium Titanate Material

Xi-Yang Li,Qian-Lin Chen,Min Yang,Ya-Nan Li,Jing-Bo Ma 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2019 NANO Vol.14 No.3

The lithium titanium spinel Li4Ti5O12 has attracted more and more attention as anode materials applied in lithium ion batteries. Li4Ti5O12 material has been found to be able to intercalate lithium ions without deformation of the lattice. However, compared with graphite and other anode materials, the low conductivity of Li4Ti5O12 restricts its charging and discharging rate. Doping is deemed to be a businesslike method to enhance ionic and electronic conductivity of Li4Ti5O12. This paper reviews the effects of Li4Ti5O12 with different doping ions on different crystal lattice states. And it has been found by a summary that the doping objective of doping ions at Li4Ti5O12 is also different. Moreover, the applications of ion doping in different fields of Li4Ti5O12 are prospected.

Particle size distributions and concentrations above radiators in indoor environments: Exploratory results from Xi`an, China

Xi Chen,Angui Li 대한환경공학회 2015 Environmental Engineering Research Vol.20 No.3

Particulate matter in indoor environments has caused public concerns in recent years. The objective of this research is to explore the influence of radiators on particle size distributions and concentrations. The particle size distributions as well as concentrations above radiators and in the adjacent indoor air are monitored in forty-two indoor environments in Xi’an, China. The temperatures, relative humidity and air velocities are also measured. The particle size distributions above radiators at ten locations are analyzed. The results show that the functional difference of indoor environments has little impact on the particle size distributions above radiators. Then the effects of the environmental parameters (particle concentrations in the adjacent indoor air, temperatures, relative humidities and air velocities) on particle concentrations above radiators are assessed by applying multiple linear regression analysis. Three multiple linear regression models are established to predict the concentrations of PM10, PM2.5 and PM1 above radiators.

Analytical calculation method for the axial equivalent elastic modulus of laminated FRP pipes based on three-dimensional stress state

Li Chen,Darong Pan,Qilin Zhao,Li-Cheng-Xi Huang,Liang Chen,Wei Xu 국제구조공학회 2021 Structural Engineering and Mechanics, An Int'l Jou Vol.77 No.1

In engineering design, the axial equivalent elastic modulus of laminated FRP pipe was mostly calculated by the average elastic modulus method or the classical laminated plate theory method, which are based on relatively simplified assumptions, and may be not accurate enough sometimes. A new analytical calculation method for the axial equivalent elastic modulus of laminated FRP pipe was established based on three-dimensional stress state. By comparing the results calculated by this method with those by the above two traditional analytical methods and the finite element method, it is found that this method for the axial equivalent elastic modulus fits well not only for thin-walled pipes with orthotropic layers, but also for thick-walled pipes with arbitrary layers. Besides, the influence of the layer stacking on the axial equivalent elastic modulus was studied with this method. It is found that a proper content of circumferential layer is beneficial for improving the axial equivalent elastic modulus of the laminated FRP pipe with oblique layers, and then can reduce its material quantity under the premise that its axial stiffness remains unchanged. Finally, the meso-mechanical mechanism of this effect was analyzed. The improving effect of circumferential layer on the axial equivalent elastic modulus of the laminated FRP pipe with oblique layers is mainly because that, the circumferential fibers can restrain the rigid body rotations of the oblique fibers, which tend to cause the significant deformations of the pipe wall units and the relatively low axial equivalent elastic modulus of the pipe.

CircFam190a: a critical positive regulator of osteoclast differentiation via enhancement of the AKT1/HSP90β complex

Chen Kun,Chen Xi,Lang Chuandong,Yuan Xingshi,Huang Junming,Li Zhi,Xu Mingyou,Wu Kerong,Zhou Chenhe,Li Qidong,Zhu Chen,Liu Lianxin,Shang Xifu 생화학분자생물학회 2023 Experimental and molecular medicine Vol.55 No.-

The identification of key regulatory factors that control osteoclastogenesis is important. Accumulating evidence indicates that circular RNAs (circRNAs) are discrete functional entities. However, the complexities of circRNA expression as well as the extent of their regulatory functions during osteoclastogenesis have yet to be revealed. Here, based on circular RNA sequencing data, we identified a circular RNA, circFam190a, as a critical regulator of osteoclast differentiation and function. During osteoclastogenesis, circFam190a is significantly upregulated. In vitro, circFam190a enhanced osteoclast formation and function. In vivo, overexpression of circFam190a induced significant bone loss, while knockdown of circFam190a prevented pathological bone loss in an ovariectomized (OVX) mouse osteoporosis model. Mechanistically, our data suggest that circFam90a enhances the binding of AKT1 and HSP90β, promoting AKT1 stability. Altogether, our findings highlight the critical role of circFam190a as a positive regulator of osteoclastogenesis, and targeting circFam190a might be a promising therapeutic strategy for treating pathological bone loss.

Solid Texture Synthesis and Mapping of Liver for Virtual Surgery

Chen Si-Xi,Li Jian-Wei,Chen Guo-Dong 보안공학연구지원센터 2016 International Journal of Hybrid Information Techno Vol.9 No.12

In order to see clearly the details inside the liver and enhance the users’ visual presence in the virtual surgery simulation system, the principles and methods of solid texture are used to render the photorealistic liver. Firstly, the sample sets are processed and multiple samples are used to synthesize the liver solid texture. Secondly, to improving the mapping efficiency of graphics hardware, the texture atlas is used to map the solid texture. In order to improve the fill rate of texture atlas, the height descending triangle bounding box method is used. The experimental result shows that the internal texture can be observed clearly. The study is of great significance to the photorealistic rendering of virtual liver surgery system, and provides a guideline for the solid texture synthesis and mapping of other human organs.

Plant Virome Analysis by the Deep Sequencing of Small RNAs of Fritillaria thunbergii var. chekiangensis and the Rapid Identification of Viruses

Lu-xi Chen,Hang-kai Pan,Yu-tian Tao,Dang Yang,Hui-min Deng,Kai-jie Xu,Wen-bin Chen,Jun-min Li 한국식물병리학회 2022 Plant Pathology Journal Vol.38 No.5

Thunberg fritillary (Fritillaria thunbergii), a perennial used in traditional Chinese herbal medicine, is a members of the family Liliaceae. The degeneration of germplasm is a severe problem in the production of Fritillaria thunbergii var. chekiangensis. However, no information about viral infections of F. thunbergii var. chekiangensis has been reported. In this study, we sequenced the small RNAs of F. thunbergii var. chekiangensis from leaves and bulbs, and viruses were identified using a phylogenetic analysis and BLAST search for sequence. In addition, multiplex reverse transcriptase-polymerase chain reaction (RT-PCR) was used to rapidly detect viruses in this variety. Our study first reported that five viruses infected F. thunbergii var. chekiangensis. Among them, fritillary virus Y (FVY), lily mottle virus (LMoV), Thunberg fritillary mosaic virus (TFMV), and hop yellow virus (HYV) had been reported in F. thunbergii, while apple stem grooving virus was first reported in the genus Fritillaria. A multiplex RT-PCR method was developed to rapidly test the four viruses FVY, LMoV, TFMV, and HYV in F. thunbergii var. chekiangensis. Our results provide a better understanding of the infection of F. thunbergii var. chekiangensis by viruses and a basic reference for the better design of suitable control measures.

Coupling membrane and Fe–Pd bimetallic nanoparticles for trichloroethene removing from water

Bangkai Li,Xi Chen,Kun Li,Chenghao Zhang,Yang He,Runhong Du,Jianzu Wang,Li Chen 한국공업화학회 2019 Journal of Industrial and Engineering Chemistry Vol.78 No.-

A novel composite membrane with membrane pores loading acrylic acid microgels coated by Fe–Pdbimetallic nanoparticles (NPs) was prepared for the dechlorination of trichloroethene (TCE) in water. Thismembrane was prepared byfirstly immobilizing acrylic acid microgels in poly (vinylidenefluoride)(PVDF) membrane pores and then in-situ synthesis of Fe–Pd bimetallic nanoparticles (NPs). The Fe–PdNPs coupled with the porous membranes enabled dechlorination to be conducted in a cross-flow modelincluding a penetrativeflow and a tangentialflow. In such a model, a large number of dechlorinationoccurred in penetrativeflowfluid while no dechlorination occurred in tangentialflowfluid. Thus,products and reactants are always timely isolated in the cross-flow dechlorination process. Thecomposite membrane prevents Fe–Pd NPs from contamination because its nanosize surface pores stopcolloids and bovine serum albumin (BSA) from entering into the membrane interior. However, thesesmall surfaces pores cannot slow the diffusion of reactants into membrane pores, and thus make the asformedcomposite membrane also show a fast dechlorination rate in a batch reaction. All in all, TCEdechlorination by the composite membrane shows many advantages including the fast dechlorinationrate, the convenient operation, the timely isolation of products from reactants, and the ignorable extrasteps for separation of metal NPs.

Terpenoid composition and the anticancer activity of Acanthopanax trifoliatus

Dong-Li Li,Xi Zheng,Yu-Chan Chen,Sen Jiang,Wei-Min Zhang,Huaqian Wang,Zhi-Yun Du,Kun Zhang 대한약학회 2016 Archives of Pharmacal Research Vol.39 No.1

The petroleum ether and ethyl acetate fractions of extract from an edible and medicinal plant Acanthopanax trifoliatus were found to show significant inhibitory effects against SF-268, MCF-7, HepG2 and NCIH460 cancer cells. Two new ursane-type triterpenoids, acantrifoic acid C (1) and acantrifoic acid D (2), along with five known triterpenoids (3–7) and eight known diterpenoids (8–15) were obtained from these two fractions. To the best of our knowledge, this is the first report concerning the isolation of compounds (5–12, 14, 15) from A. trifoliatus. Among all the isolated compounds, 3, 5 and 8 from the ethyl acetate fraction showed the strongest inhibitory effects against cancer cells, while 12 and 13 from the petroleum ether fraction showed moderate activities. These terpenoid compounds may be responsible for the anticancer activities of A. trifoliatus. Our study provides the first evidence that terpenoids from A. trifoliatus exert anticancer activities and indicates that A. trifoliatus may be a useful edible plant for further development of anticancer health supplement.

Structural and Functional Neural Alterations in Internet Addiction: A Study Protocol for Systematic Review and Meta-Analysis

Jun-Li Liu,Jing-Ting Sun,Hui-Lin Hu,Hao-Yuan Wang,Yun-Xi Kang,Tian-Qi Chen,Zhu-Hong Chen,Yu-Xuan Shang,Yu-Ting Li,Bo Hu,Rui Liu 대한신경정신의학회 2023 PSYCHIATRY INVESTIGATION Vol.20 No.1

A growing number of neuroimaging studies have revealed abnormal brain structural and functional alterations in subjects with internet addiction (IA), however, with conflicting conclusions. We plan to conduct a systematic review and meta-analysis on the studies of voxelbased morphometry (VBM) and resting-state functional connectivity (rsFC), to reach a consolidated conclusion and point out the future direction in this field. A comprehensive search of rsFC and VBM studies of IA will be conducted in the PubMed, Cochrane Library, and Web of Science databases to retrieve studies published from the inception dates to August 2021. If the extracted data are feasible, activation likelihood estimation and seed-based d mapping methods will be used to meta-analyze the brain structural and functional changes in IA patients. This study will hopefully reach a consolidated conclusion on the impact of IA on human brain or point out the future direction in this field.

Xanthones from Garcinia paucinervis with in vitro anti-proliferative activity against HL-60 cells

Da-Hong Li,Chen-Xi Li,Cui-Cui Jia,Ya-Ting Sun,Chun-Mei Xue,Jiao Bai,Hui-Ming Hua,Xiao-Qiu Liu,Zhan-Lin Li 대한약학회 2016 Archives of Pharmacal Research Vol.39 No.2

Three new xanthones, paucinervins H–J (1–3), as well as eleven known compounds (4–14), were isolated from the leaves of Garcinia paucinervis. The structures of the new compounds (1–3) were elucidated by 1D, 2D NMR spectra and HR ESIMS. In vitro antiproliferative activity against human promyelocytic leukemia HL-60 cells was tested, among which, compounds 2, 5, 6 and 7 exhibited strong growth inhibitory effects with GI50 values ranging from 1.30 to 9.08 lM, respectively. Preliminary SARs were also discussed.