Poster Session : PS 0831 ; Upper GI Tract : Clinical Factors to Predict Angiographically Detectable Non-Variceal Upper Gastrointestinal Bleeding in Patients Refractory to Endoscopic Treatment

( Tae Hwan Ha ),( Tae Hoon Oh ),( Sung In Yu ),( Min Kim ),( Jong Wook Kim ),( Won Ki Bae ),( Jae Hyung Kim ),( Seung Suk Baek ),( Mi Jin Ryu ),( Ye Na Choi ),( Ji Young Park ),( Eileen L Yoon ),( Tae 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

Background: Non-variceal upper GI bleeding (NVUGIB) is a common medical problem that has signifi cant association with morbidity and mortality. Angiographic detection and subsequent transarterial embolization (TAE) is a primary treatment option when medical and endoscopic treatments fail. We investigated clinical factors that could affect the success of the angiographic detection and prognosis after TAE in patients with NVUGIB refractory to endoscopic therapy. Methods: A retrospective analysis of the clinical data was done in patients with failed endoscopic treatment who underwent angiography for the treatment of acute NVUGIB between May 2002 and May 2013. Patients were divided into detection or non-detection groups according to the presence of bleeding stigmata in angiographic fi nding. Rebleeding defi ned as subsequent bleeding event within 7 days and mortality within 30days were analyzed as outcome parameters after TAE following detection in angiography. Results: A total 45 patients 37 (male, mean age, 65.9±14.9 years) were analyzed and classifi ed as a detection group (n=25, 55.5%) and non-detection group (n=20, 44.6%). Peptic ulcers were the most common cause of refractory NVUGIB. Larger transfusion amount (5.7±3.9 unit vs. 3.5±2.8 unit; P=0.03), prolonged aPTT level (34.2±17.3 sec vs. 21.8±13.8 sec; P=0.01) and short time interval between last endoscopy and angiography (17.5±25.9 hours vs. 34.3±59.5 hours; P=0.04) were found to be signifi cant factors for predicting angiographic detection. TAE was performed in all patients detected in angiography. Rebleeding (44%) was significantly associated with higher Rockall score (8.3±1.5 vs. 6.6±2.4; P=0.046) and mortality (12%) was signifi cantly associated with higher Rockall score (9.3±0.6 vs. 7.1±2.2; P=0.002) and higher level of BUN (55.3±47.4 vs. 27.6±17.4; P=0.01). Conclusions: Clinical characteristics associated with angiographic detection in patients with NVUGIB refractory to endoscopic therapy were severe bleeding, bleeding tendency and early angiographic intervention. The Rockall score is useful parameter for predicting rebleeding and mortality after TAE.

슬관절 등속성 운동시 근골격 모델의 검증:실험 및 모의실험 연구 : 실험 및 모의실험 연구 An Experimental and Simulatio study

배태수,강성재,최경주,김신기,유재욱,진미령,문무성 대한정형외과연구학회 2003 대한정형외과연구학회지 Vol.6 No.2

한국 약용식물부터 폴리폐놀류군의 분리 및 기능성화장품소제로서의 응용

배두경,김성기,고대원,이창언,이진태,안봉전 경산대학교 생명자원개발연구소 2001 생명자원과 산업 Vol.5 No.-

For develope the functional cosmetic material. we extracted the Korean persimmon leaves in 80% ethanol solution and isolated fraction I, II, III, to use Sephadex LH-20 column. Their polyphenol quantity was 20%, 70%, 82.8% individually and fraction II, III had polyphenol which included a many flavan-3-ol skeleton structure. We investigated various biological activity such a tyrosinase, xanthin oxidase inhibition, SOD-like acivity and DPPH. Inhibitory effect of tyrosinase was inhibited 51.7%, 74.7% at 50 ppm, 500 ppm of the fraction III and SOD-like activity increased quickly at 500ppm of the fraction II, III. DPPH effect had 80% electron donate ability at 50 ppm all of the fraction and xanthin oxidase was more inhibited 80% at 50 ppm of fraction II, III. These results showed possibility that polyphenols of the Korean persimmon leaves become the functional cosmetic ingredient

가열 및 저장중 고추 oleoresin의 지질산화 및 항산화성

배태진,김현주,강훈이,최옥수 여수대학교 1994 論文集 Vol.8 No.-

Changes of lipid oxidation and antioxidative activity in modified oleoresin during heat treatment and storage were investigated. Lipid oxidation occurred somewhat to oleoresin red pepper after heat treatment for 5 hours at 150℃ and 200℃, whereas in the heat treatment at 50℃ and 100℃, occurred in little. During heat treatment for 5 hours at 100℃, oleoresin red pepper had a moderate antioxidation effect, but its antioxidation effect at 200℃ was not shown due to degradation of capsaicin. And oleoresin red pepper greatly inhibited the oxidation of soybean oil during storage at 25℃ and 40℃.

이용도가 낮은 어패류의 가수분해물을 이용한 속성액젓의 제조

배태진,최옥수 한국식품영양학회 1998 韓國食品營養學會誌 Vol.11 No.4

DiffServ 환경에서 Mobile Xcast 지원에 관한 연구

배진호,김태수,이광휘 국립7개대학공동논문집간행위원회 2003 공업기술연구 Vol.3 No.-

In the third generation of mobile computing environment, the applications that are compatible with small members of group in which the applications join the multicast sessions such as Internet phone, video conference and networked games are more prevalent. However, since the traditional multicast mechanisms supporting the mobile computing are suitable for large members of group in the multicast session, we need to consider a new mechanism to complement them. Therefore, in this paper we suggest a new multicast model that adopted explicit multicast(xcast), which has more gradual deployment with legacy Internet backbone. This proposed model is cost-effective and more scalable and guarantees the QoS in mobile computing.

참모자반 2단추출액의 유동특성

배태진 여수대학교 산업기술지역개발연구소 2000 産業基術硏究所 論文集 Vol.9 No.-

The rheological property of gulf weed, Sargassum Fulvellum, extract at various concentration(Brix 5~20) was investigated. Gulf weed was extracted with two stage extraction, that extracted with 70% of ethyl alcohol at 25℃ for 1 hour I the first place, and reside was successively extracted with water(1:14, w/v) 70℃ for 2 hours. Gulf weed extract showed the movement of non-Newtonian fluid and pseudoplastic property was typically emerged. The shear rate dependence of apparent viscosity in the gulf weed extract increased as concentration go higher. As the measuring concentration of extract increase from Brix 5 to Brix 20 under constant temperature, flow behavior index(n) was decreased, whereas, consistency index(K) was increased. The flow behavior indexes in the range of Brix 5~20 of gulf weed extract were 0.68~0.85, consistency indexes were 0.0343~1.1820 Pa×s□ at 30℃. And the yield stresses were 0.002~0.885 Pa. As the measuring temperature increase from 10°C to 40℃, n was increased. Whereas, K was decreased and existence nature of temperature followed Arrhenius equation. And the activation energy of gulf weed extract with the range of Brix 5~20 was 2,0635~3.1958 J/kg×mol. And at this time rate constants(k□) and frequency factor(A) were 0.7734~1.6793×10□Pa×s and 0.1274~0.1524 Brix□, respectively.

팽이 톱밥 人工栽培時 培地微生物相의 經時的인 密度變化

배태웅,文炳周,辛元敎,宋模烈,李鉉旭,曺東進 東亞大學校生命資源科學大學附設 農業資原硏究所 1996 農業生命資援硏究 Vol.5 No.1

팽이 재배에 있어 가장 큰 문제 중의 하나는 雜菌에 대한 汚染, 특히 細菌에 의한 피해가 극심하므로 作業段階와 栽培過程 전반에 걸쳐 培地徵生物相의 經時的인 密度變化에 따른 雜菌의 培地內 流入時期를 조사하여 汚染菌의 發生消長을 알아보기 위해 現地農家에서 시험해 본 결과 接種후 培養室에서 菌絲培養을 시작한 5일후부터 細菌이 檢出되기 시작하여 菌긁기전까지 약 25일간 0.5∼3.1×10⁴cfu/g의 密度를 보였으나 經時的인 密度增加는 없었고, 菌絲培養이 끝난 뒤 菌긁기직후부터 細菌의 密度는 118.3×10⁴cfu/g으로 급격히 높아졌으며 子實體生育 기간동안에 시간이 경과함에 따라 密度가 현저하게 증가되는 경향을 나타냈다. 이는 培養室 안으로 흐르는 空氣를 통하여 甁內로 細菌이 流入되고 또한 菌긁기 직후 培地表面에 灌注하는 물과 加濕機에서 噴霧되는 물粒子가 細菌의 密度增加에 절대적으로 영향을 미치는 것으로 판단되므로 이때가 細菌性褐斑病菌에 感染되기 가장 용이한 시기로 생각된다. 眞菌은 菌긁기후 子實體生育 기간동안 1.17∼7.87×10⁴/g의 密度로서 菌絲培養 기간동안의 密度보다 다소 높게 檢出되었으나 대체로 經時的인 密度增加는 보이지 않았으며, 放線菌은 거의 검출되지 않거나 菌絲培養 후 5일째부터 다소 검출되기 시작했으나 밀도가 매우 낮았고 經時的으로도 증가되지 않았다. One of the most serious problem on the Enoki mushroom cultivation is the infection by pathogenicitic microorganisns, especially bacterial diseases causing serious economical losses in the mushroom production. It was carried out to find the tendency of the development of mushroom diseases by temporal changes and variation of the densities of media microflora through the cultivation periods and working stages in a mushroom farm. According to the results, several bacteria were detected from the fifth day after the inoculation and incubation of mycelium in the incubation room, and the density of bacterium was 0.5∼3.1×10⁴cfu/g media for 25 days before the inoculum-removing, although there was no increment of the density. Since the inoculum-removing after the spawn run, the density of bacterium was rapidly increased as 118.3×10⁴cfu/g media, and was significantly increased by time during the growth period of fruitbodies. It was hypothesized that it is the most suitable period for the pathogen infection because the bacterium might be introduced by the air in the incubation-room, and the increment of bacterium density might be affected by moisture supplied through watering or humidifier in the growing room after the inoculum-removing. Fungi were detected as the density as 1.17∼7.87×10⁴/g media and the density was slightly higher than that during the incubation period of hyphae, although there was no significant increment. Generally, the density of Actinomycetes was disregardfully low, or Actinomycetes were hardly ever found, although there was found some 5 days after incubation hyphae in few cases.

표고 버섯 중의 Branched chain amino acid Aminotransferase 의 분리정제 및 그 성질에 관한 연구

배강규,민태진,이수용 동국대학교 자연과학연구소 1987 자연과학연구 논문집 Vol.7 No.-

표고버섯중의 branched chain amino acid aminotransferase〔BCAT(EC 2,6,1,42)〕를(NH₄)₂SO₄ 분별침전, DEAE-cellulose column chromatography 및 sephades G-150겔 여과로 정제하여 그 특성을 조사하였다. 이 효소의 최적 pH는 8.5, 최적 온도는 36℃였고, 20℃이하에서 30분동안 열에 안정하였다. 이효소의 분자량은 69,000dalton이었으며, 산 가수분해하여 아미노산을 분석한 결과 18종의 서로 다른 아미노산들로 구성되어 있었다. 이 효소는 가지달린 아니노산인 L-valine, L-leucine 및 L-isoleucine에 대해서 특이성을 보였으며 phenylamine, potassium cyanide, phenylhydrazine, N-ethylmaleimide 및 p-chloromercuribenzoate에의하여 효소활성이 억제되었다. 또 한, L-leucine, a-ketoglutarate 및pyridoxal-5-phosphate에대한 이 효소의 Km값은 각 각 2.40mM, 2.98mM 및 1.74uM이었다. Branched cnain amino acid aminotransferaase 〔BCAT (EC 2.6.1.42)〕was purified by ammonium sulfate saturation. DEAE-cellulose column chromatography and sephadex G-150 gel filtration in Lentinus edodes(Berk.) Sing. Optimum pH and temperature were found to be 8.5 and 36℃, respectively. Apparent molecular weights of this enzyme was estimated 69.000 dalton by HPLC and SDS-PAGE. It showed activity toward L-leucine, L-isoleucine and L-valine as a substrate. It was ingibited by hydroxylamine, potassium cyanide, phenylgydrazine. N-ehylmaleimide, p-chloromercuribenzoate (CMB). cupric acetate and mercuric chloride. The Km values of this enzyme were determined to be 2.40mM for leucine, 2.98mM for a-ketoglutarate and 1.74μM for pyridexal-5- phospate, respectively.

이동 애드 혹 네트워크에서의 환경적응형 QoS AODV 라우팅 프로토콜에 관한 연구

裵振勝,宋東勳,吳世德,鄭燦赫,金玄郁,李光培,文泰洙,郭承郁,河載承 明知大學校 産業技術硏究所 2004 産業技術硏究所論文集 Vol.23 No.-

In this paper, we propose a bidirectional mobile Ad Hoc routing protocol based on AODV(ad-hoc on-demand distance vector routing) with QoS(quality of service) support. At presence, wireless mobile communication focuses on how to efficiently support mobility of users more than QoS guarantee. However, in order to satisfy requirement of various applications which have been or will be served, QoS guarantee between end points is a very important issue. The existing AODV routing protocol is implemented to use only BE (Best Effort) service. However, actual wireless mobile environment requires to reduce a waste of communication resources and meet with the real-time change of data paths by setting up routes with QoS support, considering available communication resources at each node in advance. Therefore, in this thesis, we propose an adaptive QoS support method using hello message in order to rapidly meet with the change of available communication resources and to smoothly perform route maintenance. For performance evaluation, we analyzed the average data reception rate. At that time, we used evaluation parameters such as node's mobility-stop time, hello message period, and packet priority, considering the node's mobility and the number of best effort/QoS data flows. As results, we found that with our proposed method the average data reception rate was increased 16.293%, 15.914%, 17.238% for 300 mobility-stop second case and 4.809%, 4.264%, 2.956% for 300 mobility-stop second case.