실내외 $NO_2$농도 및 $NO_2$개인폭로량과 이들에 영향을 미치는 요인에 관한 연구 -도시지역 주택 및 주부를 대상으로-

전진호,이채언,김준연,정요한,Chun, Jin-Ho,Lee, Chae-Un,Kim, Joon-Youn,Chung, Yo-Han 대한예방의학회 1988 Journal of Preventive Medicine and Public Health Vol.21 No.1

This study was conducted to establish the control program for preventing unfavorable health effects of nitrogen dioxide($NO_2$) exposure in homes by preparing the fundamental data for evaluation of relation-ships between $NO_2$ levels and influencing factors through measurements of indoor-outdoor $NO_2$ levels and personal $NO_2$ exposures for housewives with questionnaire survey on 172 homes in Pusan area from April to June, 1987 $NO_2$ measurements were made by using diffusion tube samplers(Palmes tube $NO_2$ sampler) for one week at 4 sites in homes ; kitchen(KIT), bedroom(BED), living room(LIV), outdoor(OUT) and near the collar of housewives(personal exposure livel, PNO). The details of questionnaire were number of household members(FAM), number of regular smokers (SMOKER), daily number of meals eaten(MEAL), type of housing units(HOUSE), location of house with distance from the heavy traffic roads as walking time(DIST), and of kitchen(KAREA), kind of cooking fuels(FUEL), cooking time of each meal(CTIME), usage of kitchen fan for cooking(FAN), type of heating facilities(HEAT) and so on of subject homes. The Obtained results were as fellows : 1) The mean $NO_2$ level was significantly higher at indoors than outdoors(p<0.01) and the kitchen $NO_2$ level was the highest with $33.7{\pm}13.6ppb$(9.5-81.5ppb). The mean personal exposure level of $NO_2$ for housewives was $20.6{\pm}8.8ppb$(3.1-46.9ppb). 2) The mean indoor $NO_2$ level was significantly higher in the group of household members above 5 than below 4(p<0.05), in detached dwellings than apartments(p<0.001), within 5 minutes of distance than over 5 minutes(p<0.001), in the group of unusing fan(p<0.001), in the group of longer cooking time(p<0.001), and it was in order of coal briquette, gas, electricity and oil by kind of cooking fuels(p<0.05). 3) Variables showing significant correlation(p<0.001) with indoor $NO_2$ level were kitchen $NO_2$ level(r=0.8677), cooking time(r=0.5921), outdoor $NO_2$ level(r=0.5192), personal $NO_2$ exposure level(r=0.4615), usage of kitchen fan(r=0.3573) and location of house(r=-0.2988) 4) As a result of multiple regression analysis, the most significant influencing variable to the kitchen $NO_2$ level was cooking time[KIT=$-0.378{\pm}11.772$(CTIME)+0.298(OUT)+3.102(FAN)], it was kitchen $NO_2$ level to the indoor $NO_2$ level[IND=6.996+0.458(KIT)+0.230(OUT)-1.127(KAREA)], and it was indoor $NO_2$ level to the personal $NO_2$ exposure level[PNO=15.562+0.729(IND)-4.542(DIST)-0.200(KIT)] 5) It was recognized that aritificial ventilation in the kitchen, suppression of unnecessary combustion and replacement of cooking fuel, as much as possible, were effective means for decreasing indoor $NO_2$ levels in homes.

한국인 폐암환자와 대조군의 CYP2D6 유전적 다형성에 관한 연구

전진호,이창희,엄상화,손병철,박준한,정귀옥,손창학,윤혜경,손춘희,김형인,정진숙,Chun, Jin-Ho,Lee, Chang-Hee,Urm, Sang-Hwa,Son, Byung-Chul,Park, Jun-Han,Jung, Kui-Oak,Sohn, Chang-Hak,Yoon, Hye-Kyoung,Son, Choon-Hee,Kim, Hyung-In,Jeong, J 대한예방의학회 1998 Journal of Preventive Medicine and Public Health Vol.31 No.1

The genetically determined CYP2D6 activity as considered to be associated with cancer susceptibility with inter-individual variation. Genetic polymorphism of CYP2D6(B) and CYP2D6(T) was determined by the two polymerase chain reaction(PCR) and BstN1 and EcoN1 restriction fragment length polymorphisms(RFLP) for 67 lung cancer cases and 95 healthy volunteer controls. The cases were composed of 26 squamous cell carcinoma, 14 small cell carcinoma, 10 adenocarcinoma, 3 large cell undifferentiated carcinoma, and 14 not histologically diagnosed. The results were gained from the 142 subjects (57 cases and 85 controls) who observed successfully in two PCR and BstNl/EcoN1 RELP. Only one and no mutant allele of the CYP2D6(B) and CYP2D6(T) gene was detected, that is, the frequency of mutant allele was very low; 0.7%(1/142) and 0%(0/142), respectively. Detected mutant allele of the CYP2D6(B) was beterozygous type(WM). The odds ratios for lung cancer susceptibility with CYP2D6(B) and CYP2D6(T) genotype were not calculated. These results are similar to the previous understanding that the mutant allele is very rare in Orientals compared to Caucasians, therefore, it considered that CYP2D6(B) and CYP2D6(T) genotypes have maybe no association with lung cancer susceptibility in Koreans. This is the basic data of CYP2D6(B) and CYP2D6(T) genotypes for Koreans. It would be hepful for further study to determine lung cancer susceptibility of Koreans with the data about CYP1A1, CYP2E1, GSTM1 from future study.

홍채 인식 시스템의 응용 프레임워크 구현

전진호 ( Jin-ho Chun ),김재훈 ( Jai-hoon Kim ),한경희 ( Kyung-hee Han ) 한국정보처리학회 2010 한국정보처리학회 학술대회논문집 Vol.17 No.2

홍채 인식 시스템의 응용 프레임워크는 홍채 인식기 모듈을 컴퓨터에 연결할 때 사용되는 USB 호스트 콘트롤러 드라이버와 응용 프로그램 사이에서 둘을 제어하는 스탠다드 라이브러리를 제공한다. 본 논문에서는 스탠다드 라이브러리 설계와 구현을 설명하고 있다. 스탠다드 라이브러리는 표준 호출 규약을 지키므로 응용 프로그램은 다양한 언어로 작성할 수 있다. 또한, 기존의 폴링 방식으로 구현된 스탠다드 라이브러리를 콜백을 이용하여 구현함으로써 네트워크를 통해 많은 사람들이 동시에 홍채 인식기를 사용할 때 리소스 사용을 경감할 수 있는 장점이 있다.

개인수준의 사회적 자본이 우울증에 미치는 영향

이진향(Jin Hyang Lee),박기수(Ki Soo Park),김록범(Rock Bum Kim),김봉조(Bong Jo Kim),전진호(Jin Ho Chun) 한국농촌의학 지역보건학회 2011 농촌의학·지역보건 Vol.36 No.2

본 연구는 개인수준의 사회적 자본과의 연관성을 파악하기 위해 수행되었다. 연구대상자는 2009년 지역사회 건강조사 대상자 18,104명이었다. 연구대상자의 우울증 유병률은 CES-D로 측정한 후 기준점을 16점으로 하였을 때 9.0%였으며 21점을 기준으로 하였을 때 5.7%, 25점을 기준점으로 하였을 때 3.6%였다. 대상자의 인구학적 특성, 건강행태 및 만성질환이환 여부를 통제한 후 사회적 자본과 우울증과의 관련성을 분석한 결과 요인 중 신뢰와 비공식집단 참여여부가 통계적으로 유의하였다. 신뢰하는 집단일 경우 그렇지 않은 집단에 비해 교차비가 0.536(95% CI .419∼.689)이고 비공식집단에 참여하는 집단은 그렇지 않은 집단에 비해 교차비가 0.657(95% CI .516∼.836)로 우울증이 낮았다. 인구학적 특성과 건강행태, 만성질환 이환여부에서는 연령, 결혼상태, 월소득, 흡연, 문제음주 여부, 수면시간, 체질량지수, 아침식사, 관절염 이환여부 등이 유의하게 영향을 미쳤다. 신뢰 수준과 비공식적 집단 활동 참여라는 사회적 자본이 우울증에 예방적 효과를 주므로, 보건사업의 영역에 지역 주민들의 사회적 자본을 높일 수 있는 방안을 고려하여, 이의 향상을 통해 주민들의 우울감을 낮추는 변화가 필요하다. Objectives: This study was performed to investigate the relationship between individual-level social capital and depression. Methods: Data from the 2009 Community Health Survey were analyzed for this study. We used chi-square tests and hierarchical logistic regression analyses to determine the relationship between individual-level social capital and depression. The Korean version of the Center for Epidemiological Studies-Depression Scale was used to measure depression. Results: After controlling for socio-demographic factors such as, health behavior and chronic illness morbidity, that are associated with individual-level social capital, trust and informal participation significantly affected depression. Respondents with "be trust"(0.536, 95% CI 0.419-0.685) and who participate in “informal groups”(0.657, 95% CI 0.516-0.836) had significantly lower odds ratios of depression. Conclusions: Considering and introducing measures to increase the social capital of residents, need reduce depression. It is especially necessary to enhance resident empowerment.

종합검진 수검자의 스트레스 수준과 생활습관, 자각증상 및 임상적 진단의 관련성

박준한,전진호,강장미,손병철,김대환,이창희,정귀원,엄상화,Park, Jun-Han,Chun, Jin-Ho,Kang, Jang-Mi,Son, Byung-Chul,Kim, Dae-Hwan,Lee, Chang-Hee,Jeong, Kui-Won,Urm, Sang-Hwa 대한예방의학회 1998 Journal of Preventive Medicine and Public Health Vol.31 No.4

To improve wellness and quality of life by recognizing the health efforts of stress, the author estimated the relationships between stress, subjective symptoms and clinical diagnosis through a questionnaire and a battery of specified laboratory tests; electrocardiography, blood pressure, cholesterol, aspartate aminotransferase(AST), alanine aminotransferase(ALT), gamma glutamyl transferase$(\gamma-GTP)$, fasting blood sugar, gastro-endoscopy or UGI, abdominal sonography, etc. The data was gathered from 337 clients who were undergoing multiphasic screening program at a University Hospital from January to March 1998. The mean age of subjects was $46.5{\pm}11.2$ years and the mean of body mass index was $24.0{\pm}3.7kg/m^2$. The mean vol of stress was $18.5{\pm}6.0$ expressed as the score out of 40. By general characteristics and lift style among male, mean level of stress was significantly higher in case of lower socioeconomic status, habitual drug use, longer daily working time(>10 hours), no regular exercise, drinkers, irregular meal, skip-ping breakfast(p<0.05). In case of female, that was significantly higher in case of lower education, lowe. socioeconomic status, longer daily working time(>10 hours), no regular exercise, drinkers, smokers, irregular meal, skipping breakfast(p<0.05). Significant correlations were observed between stress and subjective symptoms in all kinds of organ system (p<0.01). Correlation coefficients of stress among male were relatively high with neuro-psychiatric symptom$(\gamma=0.476)$ and cardio-vascular symptom$(\gamma=0.361)$ in order, and correlation coefficients of stress among female was highest with neuro-psychiatric symptom$(\gamma=0.371)$. The prevalence of the diagnosis through the battery of laboratory tests was high in upper gastrointestinal disorders and hypercholesterolemia in order in both sex group. Among male the mean score of stress was significantly high in ulcerative peptic disorder of upper gastrointestine and hepatopathy in order (p<0.05) . Among female that was significantly high in diabetes mellitus. In summary, it is likely that there are associations between stress, subjective symptoms and clinical diagnosis. To promote wellness and quality of life it would be of value that periodic stress evaluation program and stress management including apropriate control of smoking and drinking, regular exercise and meal.

한국인의 자가평가 건강수준 측정도구(KHP 1.0) 개발

양진선,전진호,Yang, Jin-Sun,Chun, Jin-Ho 대한예방의학회 2003 예방의학회지 Vol.36 No.1

Objectives : The 1990s has seen advances in the conceptualization of self-perceived health status which has important roles for individual health and the quality of life. Many types of standardized questionnaires have been developed with the current wide use of SF-36, NHP, andEuroQol. However, the outcomes of these tools may be different with regard to regional, cultural and emotional backgrounds. The purpose of this study was to trial the development of a Korean Health Profile (KHP 1.0) to measure the self-perceived health stati of Koreans. Methods : The KHP 1.0 was designed on the basis of the Medical Outcome Study Form 36 (SF-36), the Nottingham Health Profile (NHP), and the EuroQOL. It was composed of 9 scales; physical functioning, role limitation-physical, pain, general health, energy, social isolation, sleep, role limitation-emotional, and e-motional health. Self-reported chronic disease conditions, and the Zung's Self-Rating Depression Scale (SDS), were also checked for the evaluation of clinical validity. This study was conducted, from December 2000 to January 2001, on 800 middle-aged parents, with four high school students, with 100 retest sets being conducted two weeks later. From the 800 subjects there were 588 complete responses (effective response 73.5%). The reliability of the test-retest results, and the factor analysis on the validity of the KHP 1.0 components, were evaluated using the SPSS (ver 10.0) software. Results : The reliability of the KHP 1.0 was good with Cronbach's alpha (>0.6), test-retest correlation coefficients (>0.5), but with no significant differences from the paired t-test. From the psychometric validity tests, the 9 scales of the KHP 1.0 were divided into two components; physical and mental, and trimmed to the established model with 55% of the total variance, with the exception of role limitation-emotional. The clinical validity on the basis of the comparison for the four characteristic groups; healthy, physical conditions only, mental conditions only, and physical and mental conditions were also good. Conclusions : The KHP 1.0 appears to be a valid measurement tool of self-perceived health stati of Koreans, although there are limitations, i.e. sample size was too small, a limited number of middle-aged subjects, and it was based on unconfirmed diagnoses, etc. Therefore, further study is required to standardize the assessment.

한국인의 자가평가 건강수준 평가 도구 개발을 위한 문헌 고찰

양진선,전진호,Yang, Jin-Sun,Chun, Jin-Ho 대한예방의학회 2003 예방의학회지 Vol.36 No.1

Valid evaluation of self-perceived health status is important for the promotion of individual health and quality of life, In advanced countries, many types of health profile have been developed, and currently, the SF-36, NHP, and EuroQol, etc, are widely used. However, the outcomes of these profiles may vary according to regional, cultural or emotional backgrounds. For these reasons a Korean Health Profile should be developed. In this study, we reviewed the concept of self-perceived health status, and its significance to public health, and reviewed some of the differences between the available profiles in 139 related publications. Based on this review, we are trying to develop a Korean Health Profile in order to measure the self-perceived health stati of Koreans.

C형 간염의 진단을 위한 역전사중합효소연쇄반응과 효소면역측정법의 타당성 평가

손병철,전진호,박영홍,신해림,조규일,김종한,정귀옥,이종태,이채언,백낙환,Son, Byung-Chul,Chun, Jin-Ho,Park, Yeong-Hong,Shin, Hai-Rim,Cho, Kyu-Il,Kim, Jong-Han,Jung, Kui-Oak,Lee, Jong-Tae,Lee, Chae-Un,Paik, Nak-Whan 대한예방의학회 1995 예방의학회지 Vol.28 No.2

This study was conducted to estimate the validity of reverse transcriptase-polymerase chain reaction(RT-PCR) compared to enzyme immunoassay(EIA) for the detection of hepatitis C virus (HCV) infection. EIA for antibody to HCV(anti-HCV) and RT-PCR for HCV was executed on the subjects from Pusan and Kyungnam area with questionnaire survey to collect some relating factors of HCV infection. As the result from 617 cases, the prevalence of HCV infection was 1.5% by EIA and 3.7% by RT-PCR(p<0.05), and the age standardized rate was 1.7% and 3.4% by EIA and RT-PCR, respectively. The prevalence of hepatitis B surface antigen(HBsAg) was 6.8% by enzyme linked immunosorbent assay(ELISA) and the age standardized rate was 7.7%. It was the higher in male group comparing to female group(p<0.01). Both of the prevalence of HCV and HBsAg were higher in elevated asparate aminotransferase(AST) and alanine aminotransferase (ALT) group than in normal AST and ALT group(p<0.01). There was no specific risk factor of HCV infection. Though the degree of agreement of EIA and RT-PCR by gamma statistics was 97.2%, it showed a significant difference between the two methods(p<0.01). For the detection of HCV infection, positive predictive value of EIA was 66.7% and negative predictive value of EIA was 97.2%. This study suggests that negative result to anti-HCV by EIA didn't mean the free state of HCV infection, therefore it would be helpful that further monitoring for HCV infection by RT-PCR in the case of elevated AST and ALT and/or clinically suspected.

유료노인장기요양보호서비스 이용의사 결정요인

유진영,전진호,Yoo, Jin-Yeong,Chun, Jin-Ho 대한예방의학회 2005 예방의학회지 Vol.38 No.1

Objectives : To help develop strategies to cope with the changes arising from the rapid aging process by predicting the determining factors of intention to actual use of the charged long-term care services for elderly as perceived by the middle aged who play the major role of supports. Methods : Subjects were the parents (men 177, women 507) in their 40s of the students selected from a university of Busan city. A questionnaire survey was conducted for 4 weeks in October 2003 about the knowledge for long-term care service, the intention of actual use, and the preferences about the type of service suppliers. Data analysis was performed with frequency, chi-square test, and t-test using SPSS program (ver 10.0K), along with data mining using decision tree of Enterprise Miner V8.2 by SAS. Results : About half of the subjects (53.7%) had the actual experiences of elderly supports. Intentions to use the charged services were relatively high in home visiting nursing care service (40.1%) and long-term care facilities service (40.4%), and were influenced by previous knowledge about the services. The intentions were stronger in women, those with higher education, and those with greater income levels. Actual elderly supports were mostly (80%) done by women, and the perceived burdens for the supports were bigger in women and those of lower socioeconomic level. Desired charges were about 10,000 won for the bath service, 20,000 won for the rests services per day, and about 500,000 won for the long-term care facilities service per month. From the result of decision tree analysis, the job professionalism was the most important determining factor of intention to actual use of the services with validation as $63{\sim}71%$. Health and welfare mixed type facilities were preferred, and the most important consideration was the level of professionalism. Conclusions : Intention to actual use of the charged services was largely determined by the aspects of time and cost. Polices to increase the number of service suppliers and to decrease the burdens perceived by actual supporters were strongly recommended.

자살시도로 응급실에 내원한 환자의 자살 위험성과 양극성 장애 가능성의 연관성

허량,김건형,전진호,박영민,김영훈,이봉주,Huh, Lyang,Kim, Kun Hyung,Chun, Jin Ho,Park, Young Min,Kim, Young Hoon,Lee, Bong Ju 한국정신신체의학회 2015 정신신체의학 Vol.23 No.2

연구목적 본 연구는 자살 시도자를 대상으로 자살 생각의 심각성과 관련된 요인들을 찾아보고자 하였다. 방 법 일 대학병원 응급실에 자살 시도로 내원한 환자 중 50명을 대상으로 임상가가 면담, Columbia Suicide Severity Rating Scale(C-SSRS), Beck Depression Inventory(BDI), Korean Version of Mood Disorder Questionnaire(K-MDQ), Bipolar Spectrum Diagnostic Scale(BSDS)를 시행하였다. 결 과 자살 경향이 높은 고위험군은 C-SSRS의 자살 생각의 심각성 점수와 BDI 점수가 높았고(p<0.001), MDQ에서 양극성 장애 가능성의 양성으로 판정된 자는 자살생각의 심각성 점수가 높았다(p=0.033). 결 론 자살 시도자의 자살 생각의 심각성과 양극성 장애의 가능성은 서로 연관성이 있을 것으로 생각된다. Objectives : The aim of this study was to investigate the factors including possibility of bipolar disorder that are related to intensity of suicidal idea. Methods : The study subjects consisted of 50 patients who did suicidal attempt and treated at the Inje University Haeundae Paik Hospital Emergency Room. All participants underwent psychiatric interview and underwent Columbia Suicide Severity Rating Scale(C-SSRS), Beck Depression Inventory(BDI), Korean Version of Mood Disorder Questionnaire(MDQ) and Bipolar Spectrum Diagnostic Scale(BSDS) to evaluate patient's suicide attempt, severity of depression and possibility of bipolar disorder. Results : Compared to non-high risk group, suicide high risk group showed significantly higher BDI(p<0.001) and intensity of ideation(IOI) in C-SSRS(p<0.001). Also intensity of ideation(IOI) was correlated with Mood Disorder Questionnaire(MDQ) bipolarity positive(p=0.033). Conclusions : The present study indicated that possibility of bipolar disorder plays a significant role in suicide attempters. Assessment of suicide ideation severity and possibility of bipolar disorder should be considered when suicide attempters come to emergency room.