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      • 사무직 근로자의 B형 간염 표면 항원 및 항체 양성률과 간기능 검사와의 관계

        정귀원,정수진,유병철,엄상화,김성준,손병철,김정호,손혜숙,이종태,전진호,이채언,배기택 인제대학교 2000 仁濟醫學 Vol.21 No.2

        Objectives: It is well known that Korea is one of the endemic areas for viral Hepatitis. This study was conducted to measure the positive rates of HBsAg and Anti-HBs and investigate the relationship between hepatitis B viral markers and liver function test among the white collar workers who have been socioeconomically highly active. Methods: From January to December 1998. HBsAg and Anti-HBs were checked by RPHA(Reversed Passive Hemagglutination), and PHA (passive Hemagglutination) techniques and liver function test(AST, ALT) by Olympus EU 500 model in 12,858 white collar workers(male; 10,018, female:2,840). Author analyzed results of above items by student T test, analysis of variance, χ2 test and χ2 test for trend. Results: The positive rate of HBsAg in male was higher(7.6%) than female (4.5%) (p〈 0.01). In both sexes, the positive rates of HBsAg increased gradually as age increacted except those aged 50 and over in male(male: χ2trend=21.888 p〈 0.01, female: χ2trend = 16.188 P〈 0.01). The positive rates of Anti-HBs in both sexes were almost same such as 59.1% in male, 59.2% in female. In male, this rate increased gradually as age increased (χ2trend =20.034 p〈 0.01). In female, although this rate didn't increase gradually as age increased, there was statistical difference among each alee groups (p〈 0.01). The positive rates of HBsAg on abnormal and normal liver function were 12.1%, 6.5% in male(χ2= 18.297. p =0.011. Odds ratio=2.003). 18.0%, 4.2% in female(χ2 = 26.498 p〈 0.01, Odds ratio = 5.005) and positive rates of Anti-HBs on abnormal and normal fiver function were 59.8%, 56.5% in male and 59.3%, 55.7% in female, respectively. Conclusion: The positive rate of HBsAg in male white collar workers was higher than female (1.7 times) and it increased gradually as age increased in both sexes, hest results suggested that society and many companies have to pour effort for control of hepatitis B virus such as hot occurrence of periodic health screening examination relation to hepatitis B more frequently, sanitation and education of public health in white collar workers.

      • 서울 일부 지역 사무직 근로자들의 고혈압 유병률 및 고혈압 근로자들의 정밀 검사에 대한 조사

        정귀원,엄상화,최순석,김정호,이종태,전진호,이채언,배기택 인제대학교 1997 仁濟醫學 Vol.18 No.1

        근로 기준법 및 근로자 건강진단 실시 지침(노동부)에 의거 매년 건강진단을 받아야 하는 서울 일부 지역 근로자 1,480명(남:1.028명, 여:452명)을 조사 대상으로 고혈압의 유병률을 조사한 결과 남녀에서 각 18.8%, 6.0%였으며, 연령별로 구분한 고혈압의 비교 위험도는 40세 이상이 40세 미만보다 약 2배 높았다. 고혈압 정밀 대상자(160명)의 심전도와 안저 검사 이상율은 두항목 모두에서 정상군에 비해 높은 비율을 보였으며, 검사 항목들 간의 상관 관계에서 수축기 혈압은 이완기 혈압과, 혈청 콜레스테롤은 비만도, 중성 지질과 유의한 양(陽)의 상관 관계를 보인반면, 고밀도 지단백질은 중성 지질과 혈청 콜레스테롤과 음(陰)의 관계를 시현하였다. To determine the prevalence rate of hypertension by aging and hypertension-related factors, the authors carried out the survey of the on 1480 clerical employees and the results of detailed clinical examination (Lab data, echocardiography, fundoscopic finding) on 160 persons with hypertension in Seoul area from Jan 1, 1993 through Dec 31, 1993 The results are as follows : 1.The prevalence rate of hypertension among total subjects was 11.9% (male : 18.8%, female:6.0%), and it was gradually increasing with aging in male. 2.A prevalence rate of hypertension in subjects over 40 years old was about two times as large as that under the age of 40. 3.The prevalence rates of hypertension in obesity group(120% and over of standard body weight) and normal group(under 109% of standard body weight) were 14.1% and 6.1%. 4.The mean concentration of total cholesterol, HDL and triglyceride level in the hypertensive group were 223.7 37.1 mg/dl, 42.6 9.7 mg/dl. 197.4 61.0 mg/dl, respectively. 5.The abnormality rate in echocardiographic finding in the hypertensive group was 62.5%, and it was gradually increased as blood pressure increased. 6.The abnormality rate in fundoscopic finding of the hypertensive group was 42.5%, and it was gradually increased as systolic blood pressure increased. 7.The positivity rates of urinary protein in uristix were 1.5%(male:1.3%, female:1.7%) in normal group and 2.6% (male : 2.4%, female : 2.7% ) in hypertensive group. 8.There were positive correlation between systolic blood pressure and diastolic blood pressure; total cholesterol and index of obesity, triglyceride: and negative correlation between HDL and total cholesterol and triglyceride.

      • 요통 환자에서 공기 주입식 요부 콜셋(Disk Dr.^�)의 효용성에 대한 조사 분석

        정귀원,정수진,배기택,김병직 인제대학교 1999 仁濟醫學 Vol.20 No.2

        Analysis of the returned questionnaire after application of the air inflated lumbar corset (Disk DrR) was carried out in 328 patients. Of the 328 patients, 171 patients(52.2%) suffered from low back pain for more than 3years and 201 patients (64.3%) suffered from radicular pain with low back pain. After application of the brace, 301 patients (91.5%) reported some relief of low back pain among them, 4.6% were excellent, 36.2% were good, 21.3% were fair, 28.0% were poor and 8.2% were no effect. The mean duration of application was more than 12 hours in a day in 74.7% of the patients, this means that Disk Dr is comfortable on application relatively and the pain relief is promising. There were some tendency that the pain relief was higher with the increase of the age of the patients. Of the 328 patients, 88.1% of the patients reported that they will recommand the Disk Dr to other person.

      • SCOPUSKCI등재

        복합 유기용제 취급 근로자의 혈액 및 뇨검사 결과 분석

        정귀원,김대환,엄상화,김성준,김정호,문선순,전진호,김용완,Jeong, K.W.,Kim, D.H.,Ohm, S.H.,Kim, S.J.,Kim, J.H.,Moon, S.S.,Chun, J.H.,Kim, Y.W. 대한예방의학회 1991 Journal of Preventive Medicine and Public Health Vol.24 No.3

        To evaluate the effects on health by exposure to mixed organic solvents, the author analyzed some labortory findings of blood (hemoglobin, hematocrit RBC, WBC, SGOT, SGPT) and urine (protein, blood, sugar) that were obtained from 722 workers (male:446, female:276) who worked in plywood, painting and shoes factories in Pusan area from January to December, 1990. The result were as follows ; 1. The mean values of each hematologic findings were all within normal limit but there were significant differences at hematocrit, RBC, WBC, SGOT in male and at WBC, SGPT in female at the comparison of the mean values and the distribution according to the normal criteria by type of work. 2. There were no differences in urinalysis(protein, blood, sugar) by type of work. 3. In stepwise multiple regression, analysis of hematologic findings on age, working duration and type of work, regression coefficients on age and type of work were relatively high in male and female sub1, respectively. As a result of this study, it is considered that the measurement of WBC with morphology is significant in hematologic findings and instead of spot urine and urinstix, 24 hours urine and quantitative analysis is required in urinalysis in screening test for healthy status of workers who deal with the organic solvents.

      • 서울지역 사무직 근로자의 혈중 콜레스테롤 및 중성지방치 분석

        정귀원,김성준,정수진,손병철,손혜숙,이종태,전진호 인제대학교 2001 仁濟醫學 Vol.22 No.1

        Objectives: Among the risk factors associated with coronary arteriosclerotic disease, hyperlipidemia is one of the most important factor. In recent years, the incidence of coronary artery disease is increasing in Korean people. Authors evaluated serum total cholesterol and triglyceride level of white-collar workers who are at highly socioeconomic status and one of the high risk group of coronary artery disease. Materials and Methods: This study was carried out on 6.423 white-collar workers(male : 5,003, female : 1,420) to measure levels of serum cholesterol and triglyceride by enzymatic colorimetry method and glycerol kinase peroxidase method and their levels were analyzed in relation to sex, age, degree of obesity, and fatty liver by t-test, X2-test and X2-test for trend. Results: Mean levels of serum cholesterol and triglyceride were 205.3±58.4 mg/dl, 148.1±78.4mg/dl in male white-collar workers and 187.3±52.4mg/dl, 111.2±62.1mg/dl in female white-collar workers and levels of male were significantly higher than those of female white-collar workers(p<0.01). Serum cholesterol and triglyceride were gradually increased with age over 20' in both sexes (p<0.01) and showed significantly elevation with increment of obesity in male(p<0.01) and serum cholesterol was just increased with that in female(p<0.01). Although triglyceride was no tendency of increment with that in female, there was statistical difference between below 110% and over 111% of obesity(p<0.05). Serum cholesterol and triglyceride were gradually increased with grade of fatty liver in male(p<0.01) and serum triglyceride was increased with that in female(p<0.01) but serum cholesterol was statistical different among grades of fatty liver (p<0.05) Conclusions: Serum cholesterol and triglyceride levels of subjects were influenced by age, sex, degree of obesity, and fatty liver. It is impossible to control aging process, but if we make them to improve obesity and fatty liver by taking moderate exercise. reducing body weight, changing dietary life and alcohol drinking habit, we will contribute to health promotion related to coronary arteriosclerotic disease in white-collar workers.

      • 복합유기용제 폭로 근로자와 종합검진 수검자와의 혈액 및 요검사 비교 분석

        정귀원,전진호,김성준,엄상화,김대환,최성용,유영진,이채언 인제대학교 1994 仁濟醫學 Vol.15 No.1

        복합유기용제에 노출되어 있는 산업장의 근로자와 노출된 기왕력이 없는 종합검진 수검자, 총 447명을 대상으로 1990년 1월 1일부터 1년간 부산백병원 건강관리과 및 종합검진센터에서 일반 혈액 검사와 요검사를 조사 ㆍ 분석한 결과 혈색소, 적혈구수 백혈구수 항목에서 두 군에서의 평균치는 모두 정상범위 이내였으나, 기준치 이하의 비정상을 비교에서는 상기 세항목이 두 군사이에 차이를 나타냈고, 폭로군에서 실시한 근무년수와의 상관관계에서도 세 항목 공히 역상관관계를 나타내었다. To evaluate the effects on health by exposure to mixed organic solvents, the authors analyzed some laboratory findings of blood(hemoglobin, RBC, WBC, SGOT, SGPT ) and urine(protein, blood, sugar) between chronic exposed workers of mixed organic solvents(male : 132, female : 64) and clients who received health examination(male : 133, female : 118) in Pusan Paik hospital. The subjects were 477 persons in total and the study period was from Jan. 1, 1990 through Dec. 31, 1990. The results are as follows ; 1.The mean values of each hematologic findings were all within normal limit but there were significant differences at hemoglobin, RBC and WBC except their twenties in male at the comparison of mean value between two groups. 2.There were significant defferences hemoglobin, RBC, WBC in male and hemoglobin, WBC in female at the comparison of distribution according to the clinical normal criteria in two groups. 3.There were no differences in urinalysis(protein, blood, sugar) through two groups. 4.In correlation, there were negative relation between working duration and hemoglobin, RBC and WBC through male and female subject, in exposed group. As a result of this study, it is considered that the measurement of WBC with morphology and differential analysis is significant in hematologic findings and Instead of spot urine and urinstix, microscopic and quantitative analysis with 24 hours urineis required in urinalysis at screening test for healthy status of workers who deal with the organic solvents.

      • 근로자 건강진단 결과 분석과 활용 실태 조사

        정귀원,엄상화,최순석,정수진,배기택,이정열 인제대학교 1998 仁濟醫學 Vol.19 No.2

        산업안전보건법(근로자건강진단 실시규정) 및 의료보험법에 의거 1997년 1월 1일 부터 12월까지 서울지역 근로자 516명(남:381명, 여:135명)을 대상으로 일반건강진단시 실시한 각 검사 항목의 평균치는 모두 정상 범위에 있었고, 남녀별 비만도는 여자에서 정상율이 높았으며, 특히 여자 20대에서 93.8%로 가장 높았다. 고혈압의 경우 남녀별 평균 혈압은 116.8/78.3 mmHg, 109.9/71.6 mmHg, 유병율은 수축기 혈압의 기준치에 의하면 6.8%, 5.9%, 이완기 혈압에 의하면 16.0%, 8.9%로 남자에서 모두 높게 나타났다. 혈액검사 기준치에 따른 이상자율은 남녀별로 각각 혈색소 6.2% 5.2%, 적혈구 용적치 1.6%. 10.5%, 적혈구수 1.6%, 10.5%, 백혈구수 4.9%, 10.4%, 혈소판수 5.1%, 10.5%, AST 3.2%, 4.5%, ALT 22.3%, 5.9%, rGTP 8.1%, 12.6%, 총콜레스테롤 6.7%, 8.2%, 트리글리세라이드 22.8%, 14.1%, BUN 3.5%. 14.3%, Creatinine 1.5%, 28.0%, 공복시 혈당치 4.3%, 74%이었으며, B형간염 표면항원 양성율은 남녀별로 5.2%, 3.7%였고, 표면항체 양성율은 67.8%, 69.1%였다. 건강진단 결과에 따른 질병 유소견자들에 대한 사후 관리는 일반 질병 유소견자의 경우 근무중 치료가 60%(18명)로 가장 높았으며. 추적 정밀검사 8명(26.7%), 입원 요양치료 2명(6.7%), 금주, 금연, 식이습관 조절, 규칙적 운동 등 기타 의학적 조치 1명(3.3%)의 순으로 나타났고, 여자의 경우 근무중 치료와 추적 정밀검사가 6명중 각 3명씩 차지하였다. 질환 요주의자의 사후 관리에서는 남녀 모두 추적 정밀검사가 각각 23명(58.9%), 8명(47.0%)으로 가장 많았고, 다음이 근무중 치료 9명(23.0%), 5명(29.4%), 금주, 금연, 식이습관 조절, 규칙적 운동 등 기타 의학적 조치가 7명(20.0%), 4명(23.5%)순이었다. To survey the follow-up services and results of health examination among white collar workers who received health examination at Seoul Paik hospital, the authors analyzed some labaratory findings of blood(hemoglobin, hematocrit, RBC, WBC, platelet, AST ALT. r-GTP, tonal cholesterol. triglyceride, BUN, creatinine, fasting blood sugar), obesity index, blood pressure and follow-up services according to results of health examination of them. The subjects were 516 persons(male 381, female : 135) in total and study period was from Jan 1, 1997 to Dec 31, 1997. 1.Abnormal rates of obesity(120% and over standard body weight) among total subjects were 17.0% in male and 4.7% in female, and prevalence rate of hypertension were 6.8% in male, 5.9% in female by systolic pressure and 16.0% in male, 8.9% in female by diastolic pressure and it was gradually increasing with aging in total subjects. 2.The mean values of hematologic findings were all within normal limit but there were significant differences at WBC, Platelet. r-GTP, Total cholesterol, triglyceride, BUN, fasting blood sugar in male and hematocrit, total cholesterol in female between each age groups.(p<0.05) 3.Positive rate of Hepatitis type B surface Antigen and Antibody were 5.2%, 67.8% in male 3.7%, 69.1% in female each other. 4.Follow-up services of the subjects who were in abnormal conditions by health examination among white collar workers were insufficient to a view of practical management, those were treatment while on duty, putting on protectors and other recuperation, follow up study, a change of working places, shortening of working hours and restriction and prohibition of service.

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