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류마티스 관절염에서 간침범을 동반한 이차성 유전분증 -메토트렉세이트와 저용량 스테로이드에 의해 호전된 증례의 보고-
한윤주 ( Yoon Ju Han ),송찬호 ( Chan Ho Song ),신동혁 ( Dong Hyuk Sheen ),양상석 ( Sang Seok Yang ),이지연 ( Jee Youn Lee ),임용성 ( Yong Seong Lim ),송영욱 ( Yeong Wook Song ) 대한류마티스학회 2000 대한류마티스학회지 Vol.7 No.3
Amyloidosis is a heterogenous group of often fatal disorders characterized by extracellular deposition of a proteinaceous material with a unique fibrillar form in various tissues and organs. Presenting with severe hepatomegaly, a 46 year-old man who has suffered with rheumatoid arthritis lasting more than 12 years was confirmed to have secondary amyloidosis by liver biopsy. After treatment with methotrexate and low dose prednisolone, we have observed clinical improvement in which hepatomegaly was resolved remarkably. This is the first published case report of a patient with rhuematoid arthritis complicated by liver amyloidosis which partially regressed after treatment with methotrexate and prednisolone.
기마사지요법이 고혈압 환자의 생리,심리적 상태에 미치는 효과
한윤주 ( Yoon Ju Han ),강경숙 ( Kyung Sook Kang ) 경희대학교 동서의학연구소 2014 동서간호학연구지 Vol.20 No.2
Purpose: This research aims to identify the physio-psychological effects of applying a qi massage program as an independent complementary intervention for employees with hypertension in a workplace. Methods: A quasi-experimental design was employed using a nonequivalent control group with pre- and post-tests. The study was performed from August 18 to October 10, 2008 on hypertensive employees being treated with a qi massage program in a company. The control group was recruited first to prevent treatment diffusion. The experimental group was subsequently recruited and received individual treatment for 30 minutes. Collected data was analyzed using SPSS16.0 version. χ2-test, Mann-Whitney U test, Wilcoxon signed ranks test, Fisher’s exact test and paired t-test were implemented in order to examine the effects of individual intervention on patients who are treated with the qi massage program. Results: The experimental group showed a greater improvement in systolic blood pressure, diastolic pressure, stress, and quality of life than did the control group. Conclusion: A qi massage program may be implemented as a complementary intervention to effectively treat hypertensive persons.
강병국 ( Byung Kook Kang ),박남선 ( Nam Seon Park ),진대호 ( Dae Ho Jin ),안태홍 ( Tae Hong Ahn ),박민범 ( Min Bom Park ),이기조 ( Key Jo Lee ),한윤주 ( Yoon Ju Han ),박효진 ( Hyo Jin Park ) 대한소화기학회 2008 대한소화기학회지 Vol.52 No.2
Brunner`s gland adenoma is a rare tumor of duodenum. Patients are usually aymptomatic and most are discovered incidentally during the upper gastrointestinal (GI) series or esophagogastroduodenoscopy. These lesions are most commonly located in the duodenal bulb and clinical manifestations are variable. In symptomatic patients, the most common manifestations are GI hemorrhage and duodenal obstruction. On histologic examination, Brunner`s gland adenoma that causes clinical symptoms is composed of hyperplastic Brunner`s glands and contains mostly an admixture of glandular, adipose, and muscular tissues. We report a case of large Brunner`s gland adenoma causing upper gastrointestinal hemorrhage in a 47-year-old woman which was successfully removed by endoscopic resection without complications such as bleeding or perforation. Microscopically, it was entirely composed of variable Brunner`s glands. (Korean J Gastroenterol 2008;52:106-109)
역설적 반응에 의하여 동시에 결핵성 뇌농양 및 결핵성 복막염이 발생한 증례 1예
안태홍 ( Tae Hong Ahn ),박민범 ( Min Bum Park ),이기조 ( Key Jo Lee ),정은호 ( Eun Ho Jung ),김진우 ( Jin Woo Kim ),서상렬 ( Sang Yeol Suh ),강석우 ( Seok Woo Kang ),김은나 ( Eun Na Kim ),한윤주 ( Yoon Ju Han ),조삼권 ( Sam Kwon C 대한결핵 및 호흡기학회 2009 Tuberculosis and Respiratory Diseases Vol.66 No.6
역설적 반응은 감수성 있는 항결핵제를 복용중인 결핵환자에서 치료시작 당시의 병변이 악화되거나 새로운 병변이 생기는 현상이고 이는 치료실패와 감별을 요한다. 일반적으로 역설적 반응은 기존 항결핵 치료로 좋은 결과를 보이므로, 이러한 임상 경과를 잘 이해함으로써 불필요한 검사나 치료약제 변경 등을 하지 않고 적절히 치료할 수 있게 될 것이다. 저자들은 적절한 항결핵제 치료 중에도 역설적 반응으로 결핵성 뇌농양, 결핵성 복막염이 연속적으로 병발한 환자 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. While receiving appropriate treatment, patients with tuberculosis occasionally have unusual, paradoxical reactions, with transient worsening of lesions or the development of new lesions. This report is a case of tuberculosis brain abscess and tuberculosis peritonitis with intra-abdominal abscess that developed during appropriate anti-tuberculosis chemotherapy. A 45-year-old male patient had been diagnosed as with all-drug susceptible pulmonary tuberculosis with pleurisy. Subsequently, the patient underwent standard treatment with anti-tuberculosis therapy; the pulmonary lesions improved. Three months after initial treatment, the patient developed brain abscesses and peritonitis. With the addition of corticosteroid treatment, the patient`s neurologic symptoms were relieved. Exploratory laparotomy with surgical drainage was performed and a diagnosis of tuberculosis peritonitis was confirmed on biopsy. Anti-tuberculosis therapy was continued for 19 months, the patient improved eventually without further complications, although the therapeutic regimen had not been altered. In this case, the paradoxical response to treatment may have been involved in the pathogenesis of disease.
Helicobacter pylori 박멸요법 후 PyloriTek검사의 유용성
김나영,신동혁,구명숙,이계희,임선희,송찬호,이지연,양상석,한윤주,최신은 대한소화기학회 2000 대한소화기학회지 Vol.35 No.2
Background/Aims: PyloriTek test is a new reagent strip rapid urease test which needs only 60 minutes for diagnosing H. pylori infection. Its accuracy is reportedly similar to that of CLO test before eradication therapy. However, the usefulness of PyloriTek test after eradication therapy has not been evaluated yet. The present study was conducted to evaluate the usefulness of PyloriTek test in detecting H. pylori after eradication therapy. Methods: Five different test methods for identifying H. pylori infection were performed for 111 patients with peptic ulcer after H. pylori therapy: PyloriTek test, CLO test, Gram stain, Giemsa stain and culture. Results: The sensitivity and the specificity of each test were as follows: 70.0% and 100% for PyloriTek test; 93.3% and 100% for CLO test; 100% and 100% for Gram stain; 83.3% and 100% for Giemsa stain; 46.6% and 100% for culture. Among these five tests, the sensitivity of PyloriTek test was significantly lower than those of CLO test, Gram stain and Giemsa stain, but significantly higher than that of culture. Conclusions: The sensitivity of PyloriTek test (70.0%) was relatively low after eradication therapy, indicating that the usefulness of PyloriTek test is decreased after eradication therapy.
양대현,김나영,이계희,임선희,송찬호,최신은,임병철,이지연,양상석,한윤주,신동혁,노은진 대한소화기학회 2000 대한소화기학회지 Vol.36 No.4
Solitary splenic metastasis of colon cancer is uncommon and usually occurs with wide spread dissemination of the tumor. Only 8 cases of isolated splenic metastasis from colon cancer are reported in the English literature. A 26-year-old male who had received a right hemicolectomy for right colon cancer on May 1996, was hospitalized for increased carcinoembryonic antigen (CEA) level that was identified on regular follow-up. The abdomimal computed tomography (CT) revealed a 5×4×3.5 cm sized low attenuated lesion in posterior portion of spleen. On sono-guided aspiration, metastastic adenocarcinoma was confirmed. Under the diagnosis of solitary splenic metastasis, a splenectomy was performed on July 1998. We report the case with a review of literature.