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총수담관 결석의 진단에 있어서 내시경적 역행성 담췌관 조영술과 초음파 내시경의 비교
최윤미(Yun Mee Choi),김해성(Hae Sung Kim),안승익(Seung Ik Ahn),이건영(Keon Young Lee),홍기천(Kee Chun Hong),최선근(Sun Keun Choi),허윤석(Yoon Seok Hur),김세중(Sei Joong Kim),우제홍(Ze Hong Woo),신석환(Seok Hwan Shin),김형길(Hyung Gil 대한외과학회 2003 Annals of Surgical Treatment and Research(ASRT) Vol.64 No.4
박근명,최윤미,김장용,최선근,허윤석,이건영,김세중,조영업,안승익,홍기천,신석환,김경래,서정민,Park, Keun-Myoung,Choe, Yun-Mee,Kim, Jang-Young,Choi, Sun-Keun,Heo, Yoon-Seok,Lee, Keon-Young,Kim, Sei-Joong,Cho, Young-Up,Ahn, Seung-Ik,Hong, Kee-C 대한소아외과학회 2010 소아외과 Vol.16 No.2
남녀의 비는 1.8로 남아가 많았으며, 진단시 나이는 76.9 % 에서 4주 이내 신생아시기에 진단되었다. 임상증상은 복부팽만 84.6 %, 태변 배출지연이 46.1 %, 설사 와 변비가 23.1 % 였다. 무신경절의 범위가 89.7 %에서 직장 및 에스자형 결장에 한정되었으며, 전결장에 침범한 경우가 8 %였다. 69.2 %에서 결장조루술 후 근치적 수술을 시행하였으며, 30.8 %에서 바로 근치적 수술을 시행하였다. 수술 후 6개월 이상 추적은 54 % 였으며, 추적 관찰 환자 중 14.3 %에서 대변 지림을 보였고, 19.0 %에서 변비를 보였다. The aim of this study is to review our clinical experience with patients with Hirschsprung's disease (HD) Medical records of 39 children who underwent definitive surgery for HD at Inha University Hospital from September 1996 to June 2008 were analyzed by age at presentation, sex, gestational age, birth weight, clinical presentation, diagnostic tools, level of aganglionosis, surgical procedures, postoperative complications, and postoperative bowel function. Twenty-five patients (64.1 %) were males and 14 (35.9 %) were females. Thirty patients (76.9 %) were diagnosed and treated in the neonatal period. The transitional zone was at the rectosigmoid region in 89.7 %. Twenty-seven patients (69 %) were treated by preliminary colostomy or ileostomy. Twenty-four patients had the Duhamel operation, 6 patients anorectal myectomy, and 9 patients had transanal endorectal pull-through (TEP). Five of 9 patients who had the TEP procedure did laparoscopic assistance. Postoperatively, seventeen patients (83 %) passed stool once or more times per day and 3 patients had stool soiling. This study demonstrated that the majority of the patients had good results. To determine which treatment is most effective comparative review by operation method would be required.
최소영(So Young Choi),김세중(Sei Joong Kim),조영업(Young Up Cho),박재영(Jae Young Park),박정미(Jeong Mi Park),주영채(Young Chae Chu),최윤미(Yun Mee Choe),최선근(Sun Keun Choi),허윤석(Yoon Seok Heo),이건영(Keon Young Lee),안승익(Seung 대한외과학회 2009 Annals of Surgical Treatment and Research(ASRT) Vol.76 No.5
Purpose: Apocrine carcinoma of the breast is rare and there is confusion about the criteria of its histopathologic diagnosis. The purpose of this study is to investigate the clinical and pathologic characteristics of the disease. Methods: 9 patients diagnosed with apocrine carcinoma or apocrine carcinoma in situ and 1,009 patients diagnosed with non-apocrine carcinoma of the breast from April 1999 to March 2008 were retrospectively analyzed. Results: The mean age of the patients with apocrine carcinoma was 52.3 year. 5 patients (55.6%) among 9 patients with apocrine carcinoma were postmenopausal. There were 2,1 and 6 patients with stage 0, Ⅰ and Ⅱ disease, respectively according the TNM stage. These demographic and clinical differences between the patients with apocrine carcinoma and non-apocrine carcinoma were not significant. Only four patients (44.4%) were preoperatively diagnosed with apocrine carcinoma or apocrine carcinoma in situ. By surgical biopsy, additional 5 patients were diagnosed as apocrine carcinoma. In the immunohistochemical study, Bcl-2 was positive in one (12.5%) of 8 patients. p53 was positive in 4 (44.4%) of 9 patients. Expressions of estrogen and progesterone receptor were positive only in two patients (22.2%) with weakly positive staining. Androgen receptor was positively expressed in all cases (100%) of apocrine carcinoma. Overexpression of c-erb-B2 was detected in four patients. Conclusion: Treatment modality and prognosis of apocrine carcinoma are similar as non-apocrine carcinoma. But its preoperative diagnosis is more difficult than that of non-apocrine carcinoma and it shows different expression of hormone receptor. Further study is needed for the development of new hormonal therapy using androgen.
행위자 네트워크 이론(actornetworktheory)을 기반으로 한교육공학의 학문적 정체성 탐구
류재훈 ( Jae Hoon Ryu ),최윤미 ( Yoon Mee Choi ),김령희 ( Ryeong Hee Kim ),유영만 ( Yeong Mahn You ) 한국교육공학회 2016 교육공학연구 Vol.32 No.1
본 연구의 목적은 인간과 기술의 관계에 급진적 관점을 제시하는 행위자 네트워크 이론(actor-network theory: 이하에서 ANT로 표시)에 비추어 교육공학의 학문적 정체성을 탐색하는 것이다. ANT는 기술을 포함한 비인간 행위자에게 인간과 동등한 지위를 부여함으로써, 그동안 서양철학에 내재되어 있는 주체/객체, 인간/기술 등의 이분법적인 관념의 틀을 탈피하는 대안적 관점을 제시한다. 인간과 기술을 둘러싼 다양한 현상을 여러 행위자들 간의 상호작용을 통한 관계적 효과로 이해하는 ANT의 철학적 입장을 분석함으로써 교육공학의 학문적 정체성을 재조명하는 계기를 마련하고자 한다. 본 연구에서는 우선 ANT의 개념과 원리가 무엇인지를 살펴본다. 이는 ANT에 비추어 교육공학을 바라보는 관점을 확대하고자하는 본 연구의 자연스러운 출발점이 된다. ANT의 개념과 원리를 토대로 ANT를 기반으로 한 교육공학을 상정하고, 이것이 기존(실증주의, 구성주의 기반)의 교육공학과 어떠한 패러다임의 차이가 있는지 존재론적(ontological), 인식론적(epistemological), 가치론적(axiological), 방법론적(methodological) 측면에서 논의한다. ANT에 기반 한 교육공학은 첨단기술이 교육에 유입되어 적극적으로 활용되고 있는 현시점에서 기존 교육공학의 한계를 극복할 수 있는 실마리를 제공한다. The aim of this study is to explore the identity of educational technology in the light of actor-network theory(ANT), which has been considered the most radical theory of the relation of human and technology in the science and technology studies(STS) field. ANT regards artifacts and nonhuman beings like technology, as same agents like humans, and explains how the couple human/non-human should be substituted for the insurmountable dichotomy between subject and object, human and technology, entrenched in western philosophy. ANT refers phenomena surrounding people to the complex networks of heterogeneous agents such as human, nonhuman beings, and artifacts, and with the following review of ANT philosophy this study attempts to present the theoretical explication of the educational technology``s academic identity. In this regard, first, it elucidates ANT conceptual terms. Secondly, it interprets the educational technology in the light of ANT philosophy -the ontological, epistemological, axiological, methodological aspects, by comparing two dominant traditional paradigm in educational technology(positivism and constructionism), with the alternative one.
정인오(In-Oh Jeong),최윤미(Yun-Mee Choe),김장용(Jang Young Kim),최선근(Sun Keun Choi),허윤석(Yoon Seok Heo),이건영(Keon Young Lee),김세중(Sei-Joong Kim),조영업(Young Up Cho),안승익(Seung Ik Ahn),홍기천(Kee Chun Hong),신석환(Seok Hwan 대한외과학회 2009 Annals of Surgical Treatment and Research(ASRT) Vol.77 No.6
Purpose: The mortality of intestinal atresia has decreased remarkably owing to prenatal diagnosis, development of diagnosis method, neonatal intensive care, surgical technique, total parenteral nutrition and performing of early surgery. The clinical consideration of our experience about intestinal atresia would be helpful in the understanding of disease. Methods: We reviewed the clinical presentation, hospital days, diagnosis method, surgical method, postoperative early complication and mortality based on medical records, retrospectively, in 32 cases of intestinal atresia encountered at Inha University Hospital between March 1997 and May 2009. Results: The involved sites were; duodenum (n=11; 34.4%), jejunoileum (n=20; 62.5%), and colon (n=1; 3.1%). The mean postoperative fasting time was 6.38 days. The postoperative morbidity was 9.4% and mortality was 3.1%. Conclusion: Complete recovery from intestinal atresia can be insured by prompt diagnosis, early surgery and careful neonatal intensive care.
소아의 천공형 충수염에서 복강경 충수절제술 및 개복 충수절제술의 비교
박재영(Jae-Young Park),최윤미(Yun-Mee Choe),윤민영(Min-Young Yun),최선근(Sun Keun Choi),허윤석(Yoon-Seok Hur),이건영(Keon-Young Lee),김세중(Sei-Joong Kim),조영업(Young Up Cho),안승익(Seung-Ik Ahn),홍기천(Kee-Chun Hong),신석환(Seok-Hw 대한외과학회 2008 Annals of Surgical Treatment and Research(ASRT) Vol.75 No.2
Purpose: Appendectomy is the most common emergent surgical operation in children. Laparoscopic appendectomy is currently a popular procedure in children, but pediatric laparoscopic appendectomy is controversial for its efficacy and safety, especially for perforated appendicitis. We compared the efficacy and safety between laparoscopic appendectomy (LA) and open appendectomy (OA) for treating perforated appendicitis of children. Methods: This study involved a total of 69 patients who underwent appendectomy for perforated appendicitis at our institution between March 2005 and September 2007, and these patients were less than 15 years old. There were 41 patients in the LA group and 28 patients in the OA group. The demographic data, operative time, length of the hospital stay, bowel movement, pain control and complications were assessed. Results: There was no significant difference between the LA and OA groups with respect to gender, age, the operation time, the length of the hospital stay, bowel movement and pain control. There was one complication (2.4%) in the LA group and four complications (16.6%) in the OA group, but there was no significant difference (P=0.062). There was no wound infection. Conclusion: Laparoscopic appendectomy for the children with perforated appendicitis is a safe procedure. Yet we need further high quality randomized trials to compare the 2 techniques.
급성 담낭염의 진단에 있어서 <SUP>99m</SUP>Tc-Ciprofloxacin 영상의 유용성
김광(Kwang Kim),안승익(Seung-Ik Ahn),최원식(Wonsick Choe),이건영(Keon-Young Lee),최윤미(Yun Mee Choi),조영업(Young Up Cho),최선근(Sun Keun Choi),허윤석(Yoon Seok Hur),김세중(Sei Joong Kim),홍기천(Kee-Chun Hong),신석환(Seok-Hwan Shin 대한외과학회 2006 Annals of Surgical Treatment and Research(ASRT) Vol.70 No.2
SKF 525A가 흰쥐의 대동맥에서 Sodium nitroprusside, Acetylcholine, Pinacidil에 의한 이완반응에 미치는 효과
박조영(Jo Young Park),김학림(Hak Lim Kim),김주원(Ju Won Kim),신창열(Chang Yell Shin),최윤미(Yoon Mee Choi),김진학(Jin Hak Kim),안형수(Hyung Soo Ahn),손의동(Uy Dong Sohn),허인회(In Hoi Huh) 대한약학회 2000 약학회지 Vol.44 No.1
TEA, glibenclamide, L-NAME and SKF 525A-induced contraction were investigated using acetylcholine, sodium nitroprusside (SNP, NO donor) and pinacidil (ATP sensitive K+ channel opener) in rat abdominal and thoracic aorta. The relaxant effects of acetylcholine, SNP and pinacidil were not different in the abdominal aorta and in the thoracic aorta. Acetylcholine-induced relaxation was dependent on endothelial cell, but pinacidil was independent endothelia cell. In the presence of TEA, glibenclamide, L-NAME,mepacrine and SKF 525A, acetylcholine and SNP did not change, but pinacidil-induced relaxation was significantly reduced in presence of glibenclamide, which is ATP sensitive K+ channel blocker. SKF 525A, which is inhibitor of cytochrome P450 dependent epoxygenase, partially inhibited the pinacidil-induced relaxation. These results indicate that the pinacidil-induced relaxation may be mediated by ATP sensitive K+ channel and partially by EETS, which is produced by cytochrome P450 dependent epoxygenase.